Annual cost of hospitalization, inpatient rehabilitation, and sick leave for head and neck cancers in Germany

ClinicoEconomics and Outcomes Research

Volumn 5, Issue 1, 2013, Pages 203-213

  Klussmann, Jens P ^a   Schädlich, Peter K ^b   Chen, Xiaoyu ^b   Rémy, Vanessa ^c  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b IGES Institut   (Germany)

^c SANOFI PASTEUR   (France)

Author keywords

2008; Cost of illness; Economic burden; HPV; Human papillomavirus

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; COST OF ILLNESS; CROSS-SECTIONAL STUDY; DRUG COST; FEMALE; GERMANY; HEAD AND NECK CANCER; HEALTH CARE UTILIZATION; HOSPITAL CARE; HOSPITALIZATION COST; HUMAN; LARYNX CANCER; MAJOR CLINICAL STUDY; MALE; MEDICAL LEAVE; MOUTH CANCER; NUTRITIONAL COUNSELING; OROPHARYNX CANCER; PAPILLOMAVIRUS INFECTION; PHARYNX CANCER; PSYCHOSOCIAL CARE; REHABILITATION CARE; RETROSPECTIVE STUDY; SEX DIFFERENCE; SPEECH REHABILITATION; WART VIRUS;

EID: 84877984863     PISSN: None     EISSN: 11786981     Source Type: Journal    
DOI: 10.2147/CEOR.S43393     Document Type: Article

References (41)

1. Blomberg M, Nielsen A, Munk C, Kjaer SK. Trends in head and neck cancer incidence in Denmark, 1978-2007: focus on human papillomavirus associated sites. Int J Cancer. 2011;129(3):733-741.
2. St Guily JL, Borget I, Vainchtock A, Rémy V, Takizawa C. Head and neck cancers in France: an analysis of the hospital medical information system (PMSI) database. Head Neck Oncol. 2010;2:22.
3. Menzin J, Lines LM, Manning LN. The economics of squamous cell carcinoma of the head and neck. Curr Opin Otolaryngol Head Neck Surg. 2007;15(2):68-73.
4. Parkin DM, Bray F.Chapter 2: The burden of HPV-related cancers. Vaccine. 2006;24 Suppl 3:S3/11-25.
5. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM.GLOBO- CAN 2008 v 1.2, cancer incidence and mortalityworldwide in 2008: IARC CancerBase No 10 [web page on the Internet]. Lyon: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr. Accessed April 27, 2012.
6. World Health Organization (WHO). International Classification of Diseases. 10th revision. Geneva: WHO; 1990.
7. Robert Koch Institute, Society of Cancer Registries in Germany. Krebs in Deutschland 2007/2008 [Cancer in Germany 2007/2008]. Berlin: Robert Koch Institute, Society of Cancer Registries in Germany; 2012. German.
8. Klussmann JP, Weissenborn SJ, Wieland U, et al. Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas. Cancer. 2001;92(11):2875-2884.
9. Kreimer AR, Clifford GM, Boyle P, Franceschi S. Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev. 2005;14(2): 467-475.
10. Guntinas-Lichius O, Wendt T, Buentzel J, et al; Thuringian Head and Neck Cancer Study Group. Head and neck in situ carcinoma: survival analysis of the Thuringian cancer registration database. Oral Oncol. 2010;46(4):e5-e9.
11. Guntinas-Lichius O, Wendt T, Buentzel J, et al. Head and neck cancer in Germany: a site-specific analysis of survival of the Thuringian cancer registration database. J Cancer Res Clin Oncol. 2010;136(1): 55-63.
12. Lee JM, Turini M, Botteman MF, Stephens JM, Pashos CL.,Economic burden of head and neck cancer. A literature review. Eur J Health Econ. 2004;5(1):70-80.
13. Peterman A, Cella D, Glandon G, Dobrez D, Yount S.Mucositis in head and neck cancer: economic and quality-of-life outcomes. J Natl Cancer Inst Monogr. 2001;(29):45-51.
14. van Agthoven M, van Ineveld BM, de Boer MF et al. The costs of head and neck oncology: primary tumours, recurrent tumours and long-term follow-up. Eur J Cancer. 2001;37(17):2204-2211.
15. Ekwueme DU, Chesson HW, Zhang KB, Balamurugan A. Years of potential life lost and productivity costs because of cancer mortality and for specific cancer sites where human papillomavirus may be a risk factor for carcinogenesis-United States, 2003. Cancer. 2008;113(Suppl 10):2936-2945.
16. Hu D, Goldie SJ.The economic burden of noncervical human papillomavirus disease in the United States. Am J Obstet Gynecol. 2008;198(5): 500. e1-e7.
17. Federal Statistical Office Germany. Tiefgegliederte Diagnosedaten der Krankenhauspatientinnen und -patienten 2008 [Deeply structured diagnostic data of hospital patients 2008]. Federal Statistical Office Germany. Wiesbaden, Germany. 2009. Available from: https://www-ec.destatis.de. Accessed January 4, 2011. German.
18. Institute for the Hospital Remuneration System in Germany. GDRG- Browser_2008_Par21_100202.zip (G-DRG V2009 Daten 2008 gem. § 21 KHEntgG - G-DRG Browser) 2010. Editor Institute for the Hospital Remuneration System in Germany. Siegburg, Germany. 2010. Available from: http://www-g-drg.de. Accessed March 15, 2010. German.
19. German Public Pension Insurance. Statistik der Deutschen Rentenversicherung. Band 174. Rehabilitation 2008 [Statistics of the German Public Pension Insurance. Volume 174. Rehabilitation 2008]. Berlin: German Public Pension Insurance; 2009. German.
20. Federal Health Monitoring Germany. Arbeitsunfähigkeit bei AOK-Mitgliedern ohne Rentner. Jahr 2008: Arbeitsunfähigkeitsfälle, Arbeitsunfähigkeitstage, Tage je Fall (Gliederungsmerkmale: Jahre, Deutschland, Geschlecht, ICD-10) [Inability to work of compulsory members of the Local Statutory Health Insurance (AOK) without pensioners (cases and days of inability to work, days of inability to work per 100,000 compulsory members, days per case). Classification: years, Germany, sex, ICD-10]. Federal Health Monitoring Germany; 2008. Editor Federal Statistical Office Germany, Branch Bonn. Bonn, Germany. 2010. Available from: http://www.gbe-bund.de/oowa921-install/servlet/oowa/aw92/dboowasys921.xwdevkit/xwd_init?gbe.isgbetol/xs_start_neu/&p_aid=3&p_aid=91546134&nummer=683&p_sprache=D&p_indsp=-&p_aid=70513394. Accessed December 7, 2010. German.
21. German Federal Ministry of Health. Mitgliederstatistik KM6 2008 [Membership statistics KM6 2008]. German Federal Ministry of Health; 2008. Bonn. Available from: http://www.bmg.bund.de/fileadmin/redaktion/excel_statistiken/krankenversicherung/KM6-juli-08.xls. Accessed January 11, 2011. German.
22. Platzer H. Zukünftige Vergütungsstrukturen der Krankenhäuser [Future remuneration structures of hospitals]. Munich: AOK Bavaria; 2008. Available from: http://www.oberender-online.de/fileadmin/oberender/pdf/Platzer_ExpertentagungUniBayreuth_08052008.pdf. Accessed December 12, 2010. German.
23. Von der Schulenburg JM, Prenzler A, Schurer W. Cancer management and reimbursement aspects in Germany: an overview demonstrated by the case of colorectal cancer. Eur J Health Econ. 2010;10 Suppl 1: S21-S26.
24. Graf von der Schulenburg JM, Greiner W, Jost F, et al; Hanover Consensus Group. German recommendations on health economic evaluation: third and updated version of the Hanover Consensus. Value Health. 2008;11(4):539-544.
25. Federal Statistical Office Germany. Statistical Yearbook 2010 for the Federal Republic of Germany including International Tables. Wiesbaden: Federal Statistical Office Germany; 2010. German.
26. Schnee M.Sozioökonomische Strukturen und Morbidität in den gesetzlichen Krankenkassen [Socioeconomic structures and morbidity in the Statutory Health Insurance funds]. In: Böcken J, Braun B, Amhof R, editors. Gesundheitsmonitor 2008 [Health monitor 2008]. Gütersloh: Verlag Bertelsmann Stiftung; 2008:88-104. German.
27. Federal Health Monitoring Germany. Arbeitsunfähigkeit bei AOK- Mitgliedern ohne Rentner. Jahr 2008: Arbeitsunfähigkeitstage, Arbeitsunfähigkeitsfälle, Tage je Fall (Gliederungsmerkmale: Jahre, Kassenart, Versichertengruppe) [Disability at AOK members excluding pensioners. 2008: lost work days, disability cases, days per case (Classification: years, statutory health insurance group)]. Federal Health Monitoring Germany; 2008. Editor Federal Statistical Office Germany, Branch Bonn. Bonn, Germany. 2010. Available from: http://www.gbe-bund.de. Accessed January 22, 2011. German.
28. Federal Health Monitoring Germany. Arbeitsunfähigkeit bei Mitgliedern der gesetzlichen Krankenkassen insgesamt ohne Rentner. Jahr 2008: Arbeitsunfähigkeitstage, Arbeitsunfähigkeitsfälle, Tage je Fall (Gliederungsmerkmale: Jahre, Kassenart, Versichertengruppe) [Inability to work: days and cases of inability to work of the members of the Statutory Health Insurance (number and rate). Classification: years, sex, type of statutory health insurance organization, group of people insured]. Federal Health Monitoring Germany; 2008. Editor Federal Statistical Office Germany, Branch Bonn. Bonn, Germany. 2010. Available from: http://www.gbe-bund.de/oowa921-install/servlet/oowa/aw92/dboowasys921.xwdevkit/xwd_init?gbe.isgbetol/xs_start_neu/&p_aid=i&p_aid=60283303&nummer=267&p_sprache=D&p_indsp=-&p_aid=86537257. Accessed January 22, 2011. German.
29. German Public Pension Insurance. Statistik der Deutschen Rentenversicherung. Band 173. Rentenzugang 2008 [Statistics of the German Public Pension Insurance. Volume 173. Retirement 2008]. Berlin: German Public Pension Insurance; 2009. German.
30. Brecht JG, Poldrugo F, Schädlich PK. Alcoholism. The cost of illness in the Federal Republic of Germany. Pharmacoeconomics. 1996;10(5): 484-493.
31. Brecht JG, Schädlich PK. Burden of illness imposed by osteoporosis in Germany. Eur J Health Econ. 2000;1(1):26-32.
32. Schädlich PK, Brecht JG. Burden of illness imposed by venous thromboembolism as an original disease in Germany. Perfusion. 2003;16: 250-256.
33. Franz D, Roeder N, Hörmann K, Alberty J.ENT medicine and head and neck surgery in the G-DRG system 2008. HNO. 2008;56(9):874-880. German.
34. Sculpher MJ, Sargeant IR, Loizou LA, Thorpe SM, Spencer GM, Bown SG. A cost analysis of Nd:YAG laser ablation versus endoscopic intubation for the palliation of malignant dysphagia. Eur J Cancer. 1995;31A(10):1640-1646.
35. Goon PK, Stanley MA, Ebmeyer J, et al. HPV and head and neck cancer: a descriptive update. Head Neck Oncol. 2009;1:36.
36. Näsman A, Attner P, Hammarstedt L, et al. Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer. 2009;125(2): 362-366.
37. Chaturvedi AK, Engels EA, Anderson WF, Gillison ML. Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol. 2008;26(4): 612-619.
38. AOK-Health Partner. Germany-wide average base rate in 2011. Editor AOK-Bundesverband, Berlin. Available from: http://www.aokgesundheitspartner.de/bund/krankenhaus/lbfw/bfw/index_09446.html. Accessed March 6, 2013. German.
39. German Public Pension Insurance. Statistik der Deutschen Rentenversicherung. Band 189. Rehabilitation 2011 [Statistics of the German Public Pension Insurance. Volume 189. Rehabilitation 2011]. Berlin: German Public Pension Insurance; 2012. German.
40. Federal Statistical Office Germany. Statistical Yearbook Germany and International 2012. Wiesbaden: Federal Statistical Office Germany; 2012. German.
41. Giuliano AR, Palefsky JM, Goldstone S, et al. Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males. N Engl J Med. 2011;364(5):401-411.