Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration

International Journal of Neuropsychopharmacology

Volumn 16, Issue 5, 2013, Pages 1165-1167

  Shen, Haowei ^a   Kalivas, Peter W ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Heroin; long term plasticity; nucleus accumbens; prefrontal cortex

Indexed keywords

DIAMORPHINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SELF ADMINISTRATION; HEROIN DEPENDENCE; IN VIVO STUDY; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NERVE STIMULATION; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SYNAPSE;

ANALYSIS OF VARIANCE; ANIMALS; BIOPHYSICS; ELECTRIC STIMULATION; HEROIN; LONG-TERM POTENTIATION; LONG-TERM SYNAPTIC DEPRESSION; MALE; NARCOTICS; NEURAL PATHWAYS; NEURONAL PLASTICITY; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION; SYNAPSES;

EID: 84877959832     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145712001071     Document Type: Article

References (13)

1. Badiani A, Belin D, Epstein D, Calu D, et al. (2011). Opiate vs. psychostimulant addiction: the differences do matter. Nature Reviews Neuroscience 12, 685-700.
2. Goldstein RZ, Volkow ND (2011). Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nature Reviews Neuroscience 12, 652-669.
3. Huang C-C, Yeh C-M, Wu M-Y, Chang A, et al. (2011). Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens. Journal of Neuroscience 31, 4194-4203.
4. Kasanetz F, Deroche-Gamonet V, Berson N, Balado E, et al. (2010). Transition to addiction is associated with a persistent impairment in synaptic plasticity. Science 328, 1709-1712.
5. Knackstedt LA, Moussawi K, Lalumiere R, Schwendt M, et al. (2010). Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. Journal of Neuroscience 30, 7984-7992.
6. Martin M, Chen BT, Hopf FW, Bowers MS, et al. (2006). Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens. Nature Neuroscience 9, 868-869.
7. Moussawi K, Pacchioni A, Moran M, Olive MF, et al. (2009). N-acetylcysteine reverses cocaine-induced metaplasticity. Nature Neuroscience 12, 182-189.
8. Robinson TE, Kolb B (2004). Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology 47 (Suppl. 1), 33-46.
9. Shen H, Moussawi K, Zhou W, Toda S, et al. (2011). Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors. Proceedings of the National Academy of Sciences USA 108, 19407-19412.
10. van den Oever MC, Goriounova NA, Li KW, Van der Schors RC, et al. (2008). Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking. Nature Neuroscience 11, 1053-1058.
11. van den Oever MC, Lubbers BR, Goriounova NA, Li KW, et al. (2010). Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. Neuropsychopharmacology 35, 2120-2133.
12. Wolf ME (2010). The Bermuda Triangle of cocaine-induced neuroadaptations. Trends in Neurosciences 33, 391-398.
13. Yin HH, Ostlund SB, Balleine BW (2008). Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks. European Journal of Neuroscience 28, 1437-1448.