Functionalized mesoporous silica nanoparticles: A possible strategy to target cancer cells reducing peripheral nervous system uptake

Current Medicinal Chemistry

Volumn 20, Issue 20, 2013, Pages 2589-2600

  Ceresa, C ^a   Nicolini, G ^a   Rigolio, R ^a   Bossi, M ^a   Pasqua, L ^b   Cavaletti, G ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Cancer cells; Dorsal root ganglia neurons; Folic acid; Neurotoxicity; Silica nanoparticles

Indexed keywords

CISPLATIN; NANOPARTICLE; SILICA NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; NEUROBLASTOMA CELL; NEWBORN; NONHUMAN; OVARY CARCINOMA; PERIPHERAL NERVOUS SYSTEM; RAT; SYNTHESIS; TARGET CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; CELLS, CULTURED; CISPLATIN; DRUG CARRIERS; FLUORESCEIN-5-ISOTHIOCYANATE; FOLATE RECEPTOR 1; GANGLIA, SPINAL; HUMANS; MICROSCOPY, CONFOCAL; NANOPARTICLES; NEURONS; POROSITY; RATS; RATS, SPRAGUE-DAWLEY; SILICON DIOXIDE;

EID: 84877949924     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311320200007     Document Type: Article

References (33)

1. Cavaletti G.; Marmiroli P. Chemotherapy-induced peripheral neurotoxicity. Expert Opin. Drug Saf. 2004 3 535-546. (Pubitemid 39530207)
2. Quasthoff S.; Hartung H.P. Chemotherapy-induced peripheral neuropathy. J. Neurol. 2002 249 9-17. (Pubitemid 34119018)
3. Stillman M.; Cata J.P. Management of chemotherapy-induced peripheral neuropathy. Curr. Pain Headache Ren. 2006 10 279-287. (Pubitemid 44122751)
4. Cavaletti G.; Nicolini G.; Marmiroli P. Neurotoxic effects of antineoplastic drugs: the lesson of pre-clinical studies. Front Biosci. 2008 13 3506-3524. (Pubitemid 351594700)
5. Gilardini A.; Marmiroli P.; Cavaletti G. Proteasome inhibition: A promising strategy for treating cancer but what about neurotoxicity? Curr. Med. Chem. 2008 15 3025-3035.
6. Slowing I.; Trewyn B.G.; Lin V.S. Effect of surface functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human cancer cells. J. Am. Chem. Soc. 2006 128 14792-14793. (Pubitemid 44851603)
7. Liong M.; Lu J.; Kovochich M.; Xia T.; Ruehm S.G.; Nel A.E.; Tamanoi F.; Zink J.I. Multifunctional inorganic nanoparticles for imaging targeting and drug delivery. ACS Nano 2008 2 889-896.
8. Rosenholm J.M.; Meinander A.; Peuhu E.; Niemi R.; Eriksson J.E.; Sahlgren C.; Linden M. Targeting of porous hybrid silica nanoparticles to cancer cells. ACS Nano 2009 3 197-206.
9. Morelli C.; Maris P.; Sisci D.; Perrotta E.; Brunelli E.; Perrotta I; Panno M.L.; Tagarelli A.; Versace C.; Casula M.F.; Testa F.; Andó S.; Nagy J.B.; Pasqua L. PEG-templated mesoporous silica nanoparticles exclusively target cancer cells. Nanoscale 2011 3 3198-3207.
10. Thompson S.W.; Davis L.E.; Kornfeld M.; Hilgers R.D.; Standefer J.C. Cisplatin neuropathy: clinical electrophysiologic morphologic and toxicologic studies. Cancer 1984 54 1269-1275. (Pubitemid 14003522)
11. McDonald E.S.; Randon K.R.; Knight A.; Windebank A.J. Cisplatin preferentially binds to DNA in dorsal root ganglion neurons in vitro and in vivo: A potential mechanism for neurotoxicity. Neurobiol. Dis. 2005 18 305-313. (Pubitemid 40431114)
12. Ta L.E.; Espeset L.; Podratz J.; Windebank A.J. Neurotoxicity of oxaliplatin and cisplatin for dorsal root ganglion neurons correlates with platinum-DNA binding. Neurotoxicology 2006 27 992-1002. (Pubitemid 44838955)
13. Scuteri A.; Cassetti A.; Tredici G. Adult mesenchymal stem cells rescue dorsal root ganglia neurons from dying. Brain Res. 2006 1116 75-81. (Pubitemid 44485016)
14. Pasqua L.; Testa F.; Aiello R.; Cundari S.; Nagy J.B.Preparation of bifunctional hybrid mesoporous silica potentially useful for drug targeting. Microporous Mesoporous Mater. 2007 103 166-173. (Pubitemid 46810319)
15. Pasqua L.; Morelli C.; Testa F.; Sisci D.; Brunelli E.; Aiello R.; Andó S.; Nagy J.B. Preparation and cell inclusion of fluorescent folic acid functionalized mesoporous silica microspheres potentially useful for drug targeting. Stud. Surf. Sci. Catal. 2007 170 1956-1962.
16. Forster M.D.; Ormerod M.G.; Agarwal R.; Kaye S.B.; Jackman A.L. Flow cytometric method for determining folate receptor expression on ovarian carcinoma cells. Cytometry 2007 71 945-950. (Pubitemid 350076858)
17. Sudimack J.; Lee R.J. Targeted drug delivery via the folate receptor. Adv. Drug Deliv. Rev. 2000 41 147-62. (Pubitemid 30122955)
18. Rosenholm J.M.; Peuhu E.; Eriksson J.E.; Sahlgren C.; Lindén M. Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems. Nano Lett. 2009 9 3308-3311.
19. Gu J.; Fan W.; Shimojima A.; Okubo T. Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands. Small 2007 3 1740-1744. (Pubitemid 47560691)
20. Tsai C.P.; Chen C.Y; Hung Y.; Chang FH.; Mou C.Y. Monoclonal antibody-functionalized mesoporous silica nanoparticles (MSN) for selective targeting breast cancer cells. J. Mater. Chem. 2009 19 5737-5743.
21. Zhu C.L.; Song X.Y.; Zhou W.H.; Yang H.H.; Wen Y.H.; Wang X.R. An efficient cell-targeting and intracellular controlledrelease drug delivery system based on MSN-PEM-Aptamer conjugates. J. Mater. Chem. 2009 19 7765-7770.
22. Rosenholm J.M.; Peuhu E.; Bate-Eya L.T.; Eriksson J.E.; Sahlgren C.; Lindén M. Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors. Small 2010 6 1234-1241.
23. Biedler J.L.; Helson L.; Spengler B.A. Morphology and growth tumorigenicity and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 1973 33 2643-2652.
24. Nicolini G.; Miloso M.; Zoia C.; Di Silvestro A.; Cavaletti G.; Tredici G. Retinoic acid differentiated SH-SY5Y human neuroblastoma cells: An in vitro model to assess drug neurotoxicity. Anticancer Res. 1998 18 2477-2481. (Pubitemid 28386536)
25. Shapero K.; Fenaroli F.; Lynch I.; Cottell D.C.; Salvati A.; Dawson K.A. Time and space resolved uptake study of silica nanoparticles by human cells. Mol Biosyst. 2011 7 371-378.
26. Lebret V.; Raehm L.; Durand J.O.; Smaihi M.; Werts M.H.V.; Blanchard-Desce M.; Methy-Gonnod D.; Dubernet C. Folic Acid-Targeted Mesoporous Silica Nanoparticles for Two-Photon Fluorescence. J. Biomed. Nanotechnol. 2010 6 176-180.
27. Lin Y.S.; Tsai C.P.; Huang H.Y.; Kuo C.T.; Hung Y.; Huang D.M.; Chen Y.C.; Mou C.Y. Well-ordered mesoporous silica nanoparticles as cell markers. Chem. Mater. 2005 17 4570-4573. (Pubitemid 41362484)
28. Trewyn B.G.; Nieweg J.A.; Zhao Y.; Lin V.S.Y. Biocompatible mesoporous silica nanoparticles with different morphologies for animal cell membrane penetration. Chemical Engineering Journal 2008 137 23-29. (Pubitemid 351226642)
29. Huang D.M.; Hung Y.; Ko B.S.; Hsu S.C.; Chen W.H.; Chien C.L.; Tsai C.P.; Kuo C.T.; Kang J.C.; Yang C.S.; Mou C.Y.; Chen Y.C. Highly efficient cellular labeling of mesoporous nanoparticles in human mesenchymal stem cells: implication for stem cell tracking. FASEB J. 2005 19 2014-2016. (Pubitemid 41759749)
30. Fisichella M.; Dabboue H.; Bhattacharyya S.; Lelong G.; Saboungi M.L.; Warmont F.; Midoux P.; Pichon C.; Guérin M.; Hevor T.; Salvetat J.P. Uptake of functionalized mesoporous silica nanoparticles by human cancer cells. J Nanosci Nanotechnol. 2010 10 2314-2324.
31. Brevet D.; Gary-Bobo M.; Raehm L.; Richeter S.; Hocine O.; Amro K.; Loock B.; Couleaud P.; Frochot C.; Morére A.; Maillard P.; Garcia M.; Durand J.O. Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. Chem. Commun. 2009 12 1475-1477.
32. Galbiati F.; Volonte D.; Gil O.; Zanazzi G.; Salzer J.L.; Sargiacomo M.; Scherer P.E.; Engelman J.A.; Schlegel A.; Parenti M.; Okamoto T.; Lisanti M.P. Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. Proc. Natl. Acad. Sci. USA 1998 95 10257-10262.
33. Martín-Montañez E.; Acevedo M.J.; López-Téllez J.F.; Duncan R.S.; Mateos A.G.; Pavía J.; Koulen P.; Khan Z.U. Regulator of G-protein signaling 14 protein modulates Ca+ influx through Cav1 channels. Neuroreport. 2010 21 1034-1039.