Prevalence, overlap, and predictors of functional somatic syndromes in a student sample

International Journal of Behavioral Medicine

Volumn 20, Issue 2, 2013, Pages 184-193

  Fischer, Susanne ^a   Gaab, Jens ^b   Ehlert, Ulrike ^c   Nater, Urs M ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Comorbidity; Functional somatic syndromes; Predictors; Prevalence; Symptom overlap

Indexed keywords

ADULT; ANXIETY DISORDERS; COMORBIDITY; DAILY LIFE ACTIVITY; DEPRESSIVE DISORDER, MAJOR; FEMALE; HEALTH SURVEY; HUMAN; MALE; MENTAL DISORDERS; PREVALENCE; PROSPECTIVE STUDY; PSYCHOLOGY; QUESTIONNAIRE; RISK FACTOR; SOMATOFORM DISORDERS; STUDENT; SWITZERLAND; SYNDROME; YOUNG ADULT; ANXIETY DISORDER; ARTICLE; MAJOR DEPRESSION; MENTAL DISEASE; PSYCHOLOGICAL ASPECT; SOMATOFORM DISORDER;

ACTIVITIES OF DAILY LIVING; ADULT; ANXIETY DISORDERS; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; FEMALE; HEALTH SURVEYS; HUMANS; MALE; MENTAL DISORDERS; PREVALENCE; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; SOMATOFORM DISORDERS; STUDENTS; SWITZERLAND; SYNDROME; YOUNG ADULT;

EID: 84877928144     PISSN: 10705503     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12529-012-9266-x     Document Type: Article

References (83)

1. Jackson JL, Kroenke K. Prevalence, impact, and prognosis of multisomatoform disorder in primary care: a 5-year follow-up study. Psychosom Med. 2008;70:430-4.
2. de Waal MW, Arnold IA, Eekhof JA, van Hemert AM. Somatoform disorders in general practice: prevalence, functional impairment and comorbidity with anxiety and depressive disorders. Br J Psychiatry. 2004;184:470-6.
3. Nimnuan C, Hotopf M, Wessely S. Medically unexplained symptoms: an epidemiological study in seven specialities. J Psychosom Res. 2001;51:361-7.
4. Fink P, Steen Hansen M, Sondergaard L. Somatoform disorders among first-time referrals to a neurology service. Psychosomatics. 2005;46:540-8.
5. Harris AM, Orav EJ, Bates DW, Barsky AJ. Somatization increases disability independent of comorbidity. J Gen Intern Med. 2009;24:155-61.
6. Barsky AJ, Orav EJ, Bates DW. Somatization increases medical utilization and costs independent of psychiatric and medical comorbidity. Arch Gen Psychiatry. 2005;62:903-10.
7. Reyes M, Nisenbaum R, Hoaglin DC, Unger ER, Emmons C, Randall B, et al. Prevalence and incidence of chronic fatigue syndrome in Wichita, Kansas. Arch Intern Med. 2003;163:1530-6.
8. Jason LA, Richman JA, Rademaker AW, Jordan KM, Plioplys AV, Taylor RR, et al. A community-based study of chronic fatigue syndrome. Arch Intern Med. 1999;159:2129-37.
9. Perrot S, Vicaut E, Servant D, Ravaud P. Prevalence of fibromyalgia in France: a multi-step study research combining national screening and clinical confirmation: the DEFI study (determination of epidemiology of fibromyalgia). BMC Musculoskelet Disord. 2011;12:224.
10. Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum. 1995;38:19-28.
11. Drossman DA, Li Z, Andruzzi E, Temple RD, Talley NJ, Thompson WG, et al. U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci. 1993;38:1569-80.
12. Koloski NA, Talley NJ, Boyce PM. Epidemiology and health care seeking in the functional GI disorders: a population-based study. Am J Gastroenterol. 2002;97:2290-9.
13. Barsky AJ, Peekna HM, Borus JF. Somatic symptom reporting in women and men. J Gen Intern Med. 2001;16:266-75.
14. Kroenke K, Spitzer RL. Gender differences in the reporting of physical and somatoform symptoms. Psychosom Med. 1998;60:150-5.
15. Aaron LA, Buchwald D. A review of the evidence for overlap among unexplained clinical conditions. Ann Intern Med. 2001;134:868-81.
16. Kanaan RA, Lepine JP, Wessely SC. The association or otherwise of the functional somatic syndromes. Psychosom Med. 2007;69:855-9.
17. Nater UM, Fischer S, Ehlert U. Stress as a pathophysiological factor in functional somatic syndromes. Curr Psych Rev. 2011;7:152-69.
18. Yunus MB. Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes. Semin Arthritis Rheum. 2007;36:339-56.
19. Tak LM, Rosmalen JG. Dysfunction of stress responsive systems as a risk factor for functional somatic syndromes. J Psychosom Res. 2010;68:461-8.
20. Wessely S, Nimnuan C, Sharpe M. Functional somatic syndromes: one or many? Lancet. 1999;354:936-9.
21. Aggarwal VR, McBeth J, Zakrzewska JM, Lunt M, Macfarlane GJ. The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors? Int J Epidemiol. 2006;35:468-76.
22. Schur EA, Afari N, Furberg H, Olarte M, Goldberg J, Sullivan PF, et al. Feeling bad in more ways than one: comorbidity patterns of medically unexplained and psychiatric conditions. J Gen Intern Med. 2007;22:818-21.
23. Dansie EJ, Furberg H, Afari N, Buchwald D, Edwards K, Goldberg J, et al. Conditions comorbid with chronic fatigue in a population-based sample. Psychosomatics. 2012;53:44-50.
24. Lieb R, Meinlschmidt G, Araya R. Epidemiology of the association between somatoform disorders and anxiety and depressive disorders: an update. Psychosom Med. 2007;69:860-3.
25. Henningsen P, Zimmermann T, Sattel H. Medically unexplained physical symptoms, anxiety, and depression: a meta-analytic review. Psychosom Med. 2003;65:528-33.
26. Harvey SB, Wadsworth M, Wessely S, Hotopf M. The relationship between prior psychiatric disorder and chronic fatigue: evidence from a national birth cohort study. Psychol Med. 2008;38:933-40.
27. Goodwin L, White PD, Hotopf M, Stansfeld SA, Clark C. Psychopathology and physical activity as predictors of chronic fatigue syndrome in the 1958 British birth cohort: a replication study of the 1946 and 1970 birth cohorts. Ann Epidemiol. 2011;21:343-50.
28. Nicholl BI, Halder SL, Macfarlane GJ, Thompson DG, O'Brien S, Musleh M, et al. Psychosocial risk markers for new onset irritable bowel syndrome - results of a large prospective population-based study. Pain. 2008;137:147-55.
29. Gupta A, Silman AJ, Ray D, Morriss R, Dickens C, MacFarlane GJ, et al. The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology (Oxford). 2007;46:666-71.
30. Moss-Morris R, Spence MJ, Hou R. The pathway from glandular fever to chronic fatigue syndrome: can the cognitive behavioural model provide the map? Psychol Med. 2011;41:1099-107.
31. Thabane M, Simunovic M, Akhtar-Danesh N, Marshall JK. Development and validation of a risk score for post-infectious irritable bowel syndrome. Am J Gastroenterol. 2009;104:2267-74.
32. Forseth KO, Husby G, Gran JT, Forre O. Prognostic factors for the development of fibromyalgia in women with self-reported musculoskeletal pain. A prospective study. J Rheumatol. 1999;26:2458-67.
33. McBeth J, Macfarlane GJ, Benjamin S, Silman AJ. Features of somatization predict the onset of chronic widespread pain: results of a large population-based study. Arthritis Rheum. 2001;44:940-6.
34. Nater UM, Fischer S, Latanzio S, Ruoss D, Gaab J. FFSS - Fragebogen zur Erfassung funktioneller somatischer Syndrome [FFSS - Questionnaire on Functional Somatic Syndromes]. Verhaltenstherapie. 2011;21:263-5.
35. IHS. The International Classification of Headache Disorders: 2nd ed. Cephalalgia. 2004;24 Suppl 1:9-160.
36. Dworkin SF, LeResche L. Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. J Craniomandib Disord. 1992;6:301-55.
37. Galmiche JP, Clouse RE, Balint A, Cook IJ, Kahrilas PJ, Paterson WG, et al. Functional esophageal disorders. Gastroenterology. 2006;130:1459-65.
38. Tack J, Talley NJ, Camilleri M, Holtmann G, Hu P, Malagelada JR, et al. Functional gastroduodenal disorders. Gastroenterology. 2006;130:1466-79.
39. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130:1480-91.
40. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum. 1990;33:160-72.
41. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group. Ann Intern Med. 1994;121:953-9.
42. Bartha L, Baumzweiger W, Buscher DS, Callender T, Dahl KA, Davidoff A, et al. Multiple chemical sensitivity: a 1999 consensus. Arch Environ Health. 1999;54:147-9.
43. Nickel JC, Nyberg LM, Hennenfent M. Research guidelines for chronic prostatitis: consensus report from the first National Institutes of Health International Prostatitis Collaborative Network. Urology. 1999;54:229-33.
44. WHO. The ICD-10 Classification of Mental and Behavioural Disorders - Clinical Descriptions and Diagnostic Guidelines. Geneva: World Health Organization; 1992.
45. APA. Diagnostic and Statistical Manual of Mental Disorders. (4th ed, Text Revision). Washington D.C.: APA; 2000.
46. van Dixhoorn J, Duivenvoorden HJ. Efficacy of Nijmegen Questionnaire in recognition of the hyperventilation syndrome. J Psychosom Res. 1985;29:199-206.
47. Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999;282:1737-44.
48. Löwe BLSR, Zipfel S, Herzog W. PHQ-D. Gesundheitsfragebogen für Patienten. Manual Komplettversion und Kurzform. 2nd ed. Karlsruhe: Pfizer; 2002.
49. Derogatis LR. SCL-90-R. Administration, scoring and procedures manual-I for the R (evised) version. Baltimore: School of Medicine, Johns Hopkins University; 1977.
50. Franke GH. SCL-90-R. Symptom-Checkliste von L. R. Derogatis. 2nd ed. Goettingen: Beltz Test GmbH; 2002.
51. Lipowski ZJ. Somatization: the concept and its clinical application. Am J Psychiatry. 1988;145:1358-68.
52. Bigal ME, Bigal JM, Betti M, Bordini CA, Speciali JG. Evaluation of the impact of migraine and episodic tension-type headache on the quality of life and performance of a university student population. Headache. 2001;41:710-9.
53. da Costa MZ, Soares CB, Heinisch LM, Heinisch RH. Frequency of headache in the medical students of Santa Catarina's Federal University. Headache. 2000;40:740-4.
54. Sanvito WL, Monzillo PH, Peres MF, Martinelli MO, Fera MP, Gouveia DA, et al. The epidemiology of migraine in medical students. Headache. 1996;36:316-9.
55. Mitsikostas DD, Gatzonis S, Thomas A, Kalfakis II NA, Papageoergiou C. An epidemiological study of headaches among medical students in Athens. Headache. 1996;36:561-4.
56. Kurt S, Kaplan Y. Epidemiological and clinical characteristics of headache in university students. Clin Neurol Neurosurg. 2008;110:46-50.
57. Deleu D, Khan MA, Humaidan H, Al Mantheri Z, Al Hashami S. Prevalence and clinical characteristics of headache in medical students in Oman. Headache. 2001;41:798-804.
58. Ho KH, Ong BK, Chong PN. Headache characteristics in university undergraduates presenting to medical attention. Singapore Med J. 1996;37:583-4.
59. Adewuya AO, Loto OM, Adewumi TA. Pattern and correlates of premenstrual symptomatology amongst Nigerian University students. J Psychosom Obstet Gynaecol. 2009;30:127-32.
60. Balaha MH, Abd El Monem Amr M, Saleh Al Moghannum M, Saab Al Muhaidab N. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study. Pan Afr Med J. 2010;5:4.
61. Bakhshani NM, Mousavi MN, Khodabandeh G. Prevalence and severity of premenstrual symptoms among Iranian female university students. J Pak Med Assoc. 2009;59:205-8.
62. Tabassum S, Afridi B, Aman Z, Tabassum W, Durrani R. Premenstrual syndrome: frequency and severity in young college girls. J Pak Med Assoc. 2005;55:546-9.
63. Teng CT, Filho AH, Artes R, Gorenstein C, Andrade LH, Wang YP. Premenstrual dysphoric symptoms amongst Brazilian college students: factor structure and methodological appraisal. Eur Arch Psychiatry Clin Neurosci. 2005;255:51-6.
64. Adewuya AO, Loto OM, Adewumi TA. Premenstrual dysphoric disorder amongst Nigerian university students: prevalence, comorbid conditions, and correlates. Arch Womens Ment Health. 2008;11:13-8.
65. Issa BA, Yussuf AD, Olatinwo AW, Ighodalo M. Premenstrual dysphoric disorder among medical students of a Nigerian University. Ann Afr Med. 2010;9:118-22.
66. Omu FE, Al-Marzouk R, Delles H, Oranye NO, Omu AE. Premenstrual dysphoric disorder: prevalence and effects on nursing students' academic performance and clinical training in Kuwait. J Clin Nurs. 2011;20:2915-23.
67. Marklund S, Wanman A. Incidence and prevalence of myofascial pain in the jaw-face region. A one-year prospective study on dental students. Acta Odontol Scand. 2008;66:113-21.
68. Eyigor S, Ozdedeli S, Durmaz B. The prevalence of generalized soft tissue rheumatic conditions in Turkish medical students. J Clin Rheumatol. 2008;14:65-8.
69. Gulewitsch MD, Enck P, Hautzinger M, Schlarb AA. Irritable bowel syndrome symptoms among German students: prevalence, characteristics, and associations to somatic complaints, sleep, quality of life, and childhood abdominal pain. Eur J Gastroenterol Hepatol. 2011;23:311-6.
70. Suarez K, Mayer C, Ehlert U, Nater UM. Psychological stress and self-reported functional gastrointestinal disorders. J Nerv Ment Dis. 2010;198:226-9.
71. Jason LA, Taylor RR, Kennedy CL. Chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities in a community-based sample of persons with chronic fatigue syndrome-like symptoms. Psychosom Med. 2000;62:655-63.
72. White KP, Speechley M, Harth M, Ostbye T. Co-existence of chronic fatigue syndrome with fibromyalgia syndrome in the general population. A controlled study. Scand J Rheumatol. 2000;29:44-51.
73. Zondervan KT, Yudkin PL, Vessey MP, Jenkinson CP, Dawes MG, Barlow DH, et al. Chronic pelvic pain in the community - symptoms, investigations, and diagnoses. Am J Obstet Gynecol. 2001;184:1149-55.
74. Kato K, Sullivan PF, Pedersen NL. Latent class analysis of functional somatic symptoms in a population-based sample of twins. J Psychosom Res. 2010;68:447-53.
75. Janssens KA, Oldehinkel AJ, Verhulst FC, Hunfeld JA, Ormel J, Rosmalen JG. Symptom-specific associations between low cortisol responses and functional somatic symptoms: the TRAILS study. Psychoneuroendocrinology. 2012;37:332-40.
76. Kato K, Sullivan PF, Evengard B, Pedersen NL. Chronic widespread pain and its comorbidities: a population-based study. Arch Intern Med. 2006;166:1649-54.
77. Mykletun A, Jacka F, Williams L, Pasco J, Henry M, Nicholson GC, et al. Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women. BMC Gastroenterol. 2010;10:88.
78. Nater UM, Lin JM, Maloney EM, Jones JF, Tian H, Boneva RS, et al. Psychiatric comorbidity in persons with chronic fatigue syndrome identified from the Georgia population. Psychosom Med. 2009;71:557-65.
79. Rief W, Mewes R, Martin A, Glaesmer H, Brahler E. Evaluating new proposals for the psychiatric classification of patients with multiple somatic symptoms. Psychosom Med. 2011;73:760-8.
80. Lowe B, Spitzer RL, Williams JB, Mussell M, Schellberg D, Kroenke K. Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment. Gen Hosp Psychiatry. 2008;30:191-9.
81. Kato K, Sullivan PF, Evengard B, Pedersen NL. A population-based twin study of functional somatic syndromes. Psychol Med. 2009;39:497-505.
82. Leone SS, Huibers MJ, Kant I, Van Schayck CP, Bleijenberg G, Andre Knottnerus J. Long-term predictors of outcome in fatigued employees on sick leave: a 4-year follow-up study. Psychol Med. 2006;36:1293-300.
83. Thabane M, Kottachchi DT, Marshall JK. Systematic review and meta-analysis: the incidence and prognosis of post-infectious irritable bowel syndrome. Aliment Pharmacol Ther. 2007;26:535-44.