HBV core promoter mutations promote cellular proliferation through E2F1-mediated upregulation of S-phase kinase-associated protein 2 transcription

Journal of Hepatology

Volumn 58, Issue 6, 2013, Pages 1068-1073

  Huang, Yuehua ^a   Tai, Andrew W ^a,c   Tong, Shuping ^b   Lok, Anna S F ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b BROWN UNIVERSITY   (United States)

^c Ann Arbor Veterans Administration Health System   (United States)

Author keywords

Cell cycle regulators; HBx gene; Hepatocellular carcinoma

Indexed keywords

S PHASE KINASE ASSOCIATED PROTEIN 2; TRANSCRIPTION FACTOR E2F1; E2F1 PROTEIN, HUMAN; HEPATITIS B VIRUS X PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORE PROMOTER; DOWN REGULATION; GENE MUTATION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; CARCINOMA, HEPATOCELLULAR; GENETIC TRANSCRIPTION; GENETICS; LIVER NEOPLASMS; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; E2F1 TRANSCRIPTION FACTOR; HEPATITIS B VIRUS; HUMANS; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS, GENETIC; S-PHASE KINASE-ASSOCIATED PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84877924950     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.01.014     Document Type: Article

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