Treatment of constipation in older people

CMAJ. Canadian Medical Association Journal

Volumn 185, Issue 8, 2013, Pages 663-670

  Gandell, Dov ^a   Straus, Sharon E ^b   Bundookwala, Maria ^c   Tsui, Vincent ^d   Alibhai, Shabbir M H ^c  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d ST JOSEPH S HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAQUINONE; ANTIHISTAMINIC AGENT; BISACODYL; BULKING AGENT; CASCARA; DIGESTIVE TRACT AGENT; DOCUSATE CALCIUM; DOCUSATE SODIUM; GALACTOSE OLIGOSACCHARIDE; GLYCEROL; ISPAGULA; LACTITOL; LACTULOSE; LAXATIVE; MACROGOL; MAGNESIUM HYDROXIDE; MAGNESIUM OXIDE; METHYLCELLULOSE; NARCOTIC ANALGESIC AGENT; OSMOTIC AGENT; PLACEBO; POLYCARBOPHIL; PROKINETIC AGENT; PRUCALOPRIDE; SENNA EXTRACT; SENNOSIDE; SODIUM DIHYDROGEN PHOSPHATE; SORBITOL; STOOL SOFTENER; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ABDOMINAL CRAMP; ABDOMINAL PAIN; AGE; AGED; BLOATING; CONSTIPATION; DIARRHEA; DRUG HYPERSENSITIVITY; ELECTROLYTE DISTURBANCE; FEEDBACK SYSTEM; FLATULENCE; FLUID INTAKE; HEADACHE; HUMAN; HYPERMAGNESEMIA; HYPERNATREMIA; HYPERPHOSPHATEMIA; HYPERPIGMENTATION; HYPOCALCEMIA; HYPOKALEMIA; INTESTINE OBSTRUCTION; META ANALYSIS (TOPIC); NAUSEA; PIGMENT DISORDER; PREVALENCE; PSEUDOMELANOSIS COLI; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW (TOPIC); VOMITING;

EID: 84877891208     PISSN: 08203946     EISSN: 14882329     Source Type: Journal    
DOI: 10.1503/cmaj.120819     Document Type: Review

References (45)

1. Higgins PD, Johanson JF. Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol 2004;99:750-9. (Pubitemid 38612817)
2. Campbell AJ, Busby WJ, Horwath CC. Factors associated with constipation in a community based sample of people aged 70 years and over. J Epidemiol Community Health 1993;47:23-6. (Pubitemid 23078242)
3. Kinnunen O. Study of constipation in a geriatric hospital, day hospital, old people's home and at home. Aging (Milano) 1991;3:161-70.
4. Towers AL, Burgio KL, Locher JL, et al. Constipation in the elderly: influence of dietary, psychological, and physiological factors. J Am Geriatr Soc 1994;42:701-6. (Pubitemid 24213188)
5. Stewart RB, Moore MT, Marks RG, et al. Correlates of constipation in an ambulatory elderly population. Am J Gastroenterol 1992;87:859-64.
6. Young RW. The problem of fecal impaction in the aged. J Am Geriatr Soc 1973;21:383.
7. Wrenn K. Fecal impaction. N Engl J Med 1989;321:658-62.
8. Ouaïssi M, Sielezneff I, Benoist S, et al. Lethal fecaloma. J Am Geriatr Soc 2007;55:965-7.
9. Frank L, Schmier J, Kleinman L, et al. Time and economic cost of constipation care in nursing homes. J Am Med Dir Assoc 2002;3:215-23.
10. Harari D, Gurwitz JH, Avorn J, et al. How do older persons define constipation? Implications for therapeutic management. J Gen Intern Med 1997;12:63-6.
11. Ashraf W, Park F, Lof J, et al. An examination of the reliability of reported stool frequency in the diagnosis of idiopathic constipation. Am J Gastroenterol 1996;91:26-32. (Pubitemid 26026032)
12. Rome III diagnostic criteria for functional gastrointestinal disorders. Raleigh (NC): Rome Foundation; 2006. Available: www.romecriteria.org/assets/pdf/ 19-RomeIII- apA-885-898.pdf (accessed 2012 Dec. 7).
13. Camilleri M, Lee JS, Viramontes B, et al. Insights into the pathophysiology and mechanisms of constipation, irritable bowel syndrome, and diverticulosis in older people. J Am Geriatr Soc 2000;48:1142-50.
14. Gallagher P, O'Mahony D. Constipation in old age. Best Pract Res Clin Gastroenterol 2009;23:875-87.
15. Sanders JF. Lactulose syrup assessed in a double-blind study of elderly constipated patients. J Am Geriatr Soc 1978;26:236-9. (Pubitemid 8344254)
16. Vanderdonckt J, Coulon J, Denys W, et al. Study of the laxative effect of lactitol (Importal) in an elderly institutionalized, but not bedridden, population suffering from chronic constipation. J Clinical and Exp Gerontol 1990;21:171-89.
17. Wesselius-De Casparis A, Braadbaart S, Bergh-Bohlken GE, et al. Treatment of chronic constipation with lactulose syrup: results of a double-blind study. Gut 1968;9:84-6.
18. Zangaglia R, Martignoni E, Glorioso M, et al. Macrogol for the treatment of constipation in Parkinson's disease. A randomized placebo-controlled study. Mov Disord 2007;22:1239-44. (Pubitemid 47325029)
19. Cheskin LJ, Kamal N, Crowell MD, et al. Mechanisms of constipation in older persons and effects of fiber compared with placebo. J Am Geriatr Soc 1995;43:666-9.
20. Ewerth S, Ahlberg J, Holmstrom B, et al. Influence on symptoms and transit-time of Vi-SiblinR in diverticular disease. Acta Chir Scand Suppl 1980;500:49-50. (Pubitemid 11214516)
21. Rajala SA, Salminen SJ, Seppanen JH, et al. Treatment of chronic constipation with lactitol sweetened yoghurt supplemented with guar gum and wheat bran in elderly hospital inpatients. Compr Gerontol [A] 1988;2:83-6.
22. Sairanen U, Piirainen L, Nevala R, et al. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Eur J Clin Nutr 2007;61:1423-8. (Pubitemid 350245917)
23. Snustad D, Lee V, Abraham I, et al. Dietary fiber in hospitalized geriatric patients: Too soft a solution for too hard a problem? J Nutr Elder 1991;10(2):49-63.
24. Teuri U, Korpela R. Galacto-oligosaccharides relieve constipation in elderly people. Ann Nutr Metab 1998;42:319-27. (Pubitemid 29046028)
25. Surakka A, Kajander K, Rajilic-Stojanovic M. Yoghurt containing galactooligosaccharides facilitates defecation among elderly subjects and selectively increases the number of bifidobacteria. Int J Probiotics Prebiotics 2009;4:65-74.
26. Bub S, Brinckmann J, Cicconetti G, et al. Efficacy of an herbal dietary supplement (Smooth Move) in the management of constipation in nursing home residents: a randomized, double-blind, placebo-controlled study. J Am Med Dir Assoc 2006;7:556-61. (Pubitemid 44661080)
27. Huang C, Su Y, Li T, et al. Treatment of constipation in long-term care with Chinese herbal formula: a randomized, double-blind placebo-controlled trial. J Altern Complement Med 2011;17:639-46.
28. Hyland CM, Foran JD. Dioctyl sodium sulphosuccinate as a laxative in the elderly. Practitioner 1968;200:698-9.
29. Müller-Lissner S, Rykx A, Kerstens R, et al. A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation. Neurogastroenterol Motil 2010;22:991-8.
30. Simón MA, Bueno AM. Behavioural treatment of the dyssynergic defecation in chronically constipated elderly patients: a randomized controlled trial. Appl Psychophysiol Biofeedback 2009;34:273-7.
31. Xing JH, Soffer EE. Adverse effects of laxatives. Dis Colon Rectum 2001;44:1201-9. (Pubitemid 32758279)
32. Pérez-Piqueras J, Silva C, Jaqueti J. Endoscopic diagnosis and treatment of an esophageal bezoar resulting from bulk laxative ingestion. Endoscopy 1994;26:710. (Pubitemid 24361220)
33. Moss AJ. The long and short of a constipation-reducing medication. N Engl J Med 2008;358:2402-3. (Pubitemid 351749168)
34. Chassagne P, Jego A, Gloc P, et al. Does treatment of constipation improve faecal incontinence in institutionalized elderly patients? Age Ageing 2000;29:159-64. (Pubitemid 30193153)
35. Lindeman RD, Romero LJ, Liang HC, et al. Do elderly persons need to be encouraged to drink more fluids? J Gerontol A Biol Sci Med Sci 2000;55:M361-5. (Pubitemid 30439458)
36. Robson KM, Kiely DK, Lembo T. Development of constipation in nursing home residents. Dis Colon Rectum 2000;43:940-3. (Pubitemid 30464063)
37. Chin A Paw MJ, van Poppel MN, van Mechelen W. Effects of resistance and functional-skills training on habitual activity and constipation among older adults living in long-term care facilities: a randomized controlled trial. BMC Geriatr 2006;6:9.
38. Bassotti G, Chistolini F, Sietchiping-Nzepa F, et al. Biofeedback for pelvic floor dysfunction in constipation. BMJ 2004;328:393-6. (Pubitemid 38241192)
39. Brandt LJ, Prather CM, Quigley EM, et al. Systematic review on the management of chronic constipation in North America. Am J Gastroenterol 2005;100(Suppl 1):S5-21.
40. Ford AC, Suares NC. Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis. Gut 2011;60:209-18.
41. Lacy BE, Chey WD. Lubiprostone: chronic constipation and irritable bowel syndrome with constipation. Expert Opin Pharmacother 2009;10:143-52.
42. Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8.
43. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control Clin Trials 1996;17:1-12. (Pubitemid 26120810)
44. Corazziari E, Badiali D, Bazzocchi G, et al. Long term efficacy, safety, and tolerabilitity of low daily doses of isosmotic polyethylene glycol electrolyte balanced solution (PMF-100) in the treatment of functional chronic constipation. Gut 2000;46:522-6. (Pubitemid 30305817)
45. Attar A, Lemann M, Ferguson A, et al. Comparison of a low dose polyethylene glycol electrolyte solution with lactulose for treatment of chronic constipation. Gut 1999;44:226-30. (Pubitemid 29119366)