Tacrolimus-induced severe cholestasis complicating renal transplantation

Renal Failure

Volumn 35, Issue 5, 2013, Pages 735-737

  Yadav, Dinesh K ^a   Gera, Dinesh N ^a   Gumber, Manoj R ^a   Kute, Vivek B ^a   Patel, Mohan P ^a   Vanikar, Aruna V ^b   Trivedi, Hargovind L ^a  

^a Dr HL Trivedi Institute of Transplantation Sciences IKDRC ITS   (India)

^b IKDRC ITS   (India)

Author keywords

Hepatotoxicity; Renal transplant; Tacrolimus

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; COTRIMOXAZOLE; CREATININE; EVEROLIMUS; FLUCONAZOLE; GAMMA GLUTAMYLTRANSFERASE; GANCICLOVIR; HEPATITIS B VACCINE; IMMUNOGLOBULIN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; PREDNISOLONE; RITUXIMAB; TACROLIMUS; URSODEOXYCHOLIC ACID;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANOREXIA; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CASE REPORT; CHOLESTASIS; CREATININE BLOOD LEVEL; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG INDUCED DISEASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ENZYME BLOOD LEVEL; EYE DISEASE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEMODIALYSIS; HUMAN; HUMAN TISSUE; INFECTION PREVENTION; INTERSTITIAL NEPHRITIS; INTRAHEPATIC CHOLESTASIS; KIDNEY BIOPSY; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVER FUNCTION TEST; MALE; PATIENT ASSESSMENT; PRIORITY JOURNAL; PRURITUS;

ADULT; CHOLESTASIS, INTRAHEPATIC; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; TACROLIMUS;

EID: 84877849417     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2013.780621     Document Type: Article

References (8)

1. Ganschow R, Albani J, Grabhorn E, Richter A, Burdelski M. Tacrolimus-induced cholestatic syndrome following pediatric liver transplantation and steroid-resistant graft rejection. Pediatr Transplant. 2006;10(2):220-224
2. Taniai N, Akimaru K, Ishikawa Y, et al. Hepatotoxicity caused by both tacrolimus and cyclosporine after living donor liver transplantation. J Nippon Med Sch. 2008;75(3):187-191 (Pubitemid 351845554)
3. Sacher VY, Bejarano PA, Pham SM. Tacrolimus induced hepatotoxicity in a patient with bilateral lung transplant. Transpl Int. 2012;25(10):e111-e1112. doi:10.1111/j.1432-2277.2012.01546.x
4. Vallet-Pichard A, Rerolle JP, Fontaine H, et al. Veno-occlusive disease of the liver in renal transplant patients. Nephrol Dial Transplant. 2003;18(8):1663-1666 (Pubitemid 36939646)
5. Soresi M, Sparacino V, Pisciotta G, et al. Effects of cyclosporin A on various indices of cholestasis in kidney transplant recipients. Minerva Urol Nefrol. 1995;47(2):65-69
6. Lorber MI, Van Buren CT, Flechner SM, Williams C, Kahan BD. Hepatobiliary complications of cyclosporine therapy following renal transplantation. Transplant Proc. 1987;19(1 Pt 2):1808-1810 (Pubitemid 17027020)
7. Yuan QS, Zheng FL, Sun Y, Yu Y, Li Y. Rescue therapy with tacrolimus in renal graft patients with cyclosporine A-induced hepatotoxicity: A preliminary study. Transplant Proc. 2000;32 (7):1694-1695
8. Sanchez-Campos S, Lopez-Acebo R, Gonzales P, Culebras JM, Tuñon MJ, Gonzalez-Gallego J. Cholestasis and alterations of glutathione metabolism induced by tacrolimus (FK506) in the rat. Transplantation. 1998;66(1):84-88 (Pubitemid 28341172)