Cell uptake enhancement of folate targeted polymer coated magnetic nanoparticles

Journal of Biomedical Nanotechnology

Volumn 9, Issue 6, 2013, Pages 949-964

  Licciardi, Mariano ^a   Scialabba, Cinzia ^a   Cavallaro, Gennara ^a   Sangregorio, Claudio ^b,c   Fantechi, Elvira ^c   Giammona, Gaetano ^a,b  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cell uptake; Ferrozine assay; Folate targeting; Magnetic nanoparticles; Polymer coating

Indexed keywords

CELL UPTAKE; FERROZINE; FOLATE TARGETING; MAGNETIC NANO-PARTICLES; POLYMER COATING;

CELL CULTURE; CELLS; CONJUGATED POLYMERS; DRUG DELIVERY; IRON OXIDES; NANOPARTICLES; ORGANIC ACIDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; SUPERPARAMAGNETISM; TUMORS;

PLASTIC COATINGS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; FOLIC ACID; IRON OXIDE; MACROGOL; MACROGOL 2000; MAGNETIC NANOPARTICLE; POLY[N (2 HYDROXYETHYL)ASPARTAMIDE]; POLYLACTIC ACID; POLYMER;

ARTICLE; CELL STRAIN MCF 7; CELL TRANSPORT; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; DYNAMIC LIGHT SCATTERING; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTERNALIZATION; LIGHT SCATTERING; MAGNETIC FIELD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; POLYMERIZATION; SCANNING ELECTRON MICROSCOPY; TUMOR CELL;

CELL LINE, TUMOR; COATED MATERIALS, BIOCOMPATIBLE; FOLIC ACID; HUMANS; MAGNETITE NANOPARTICLES; MATERIALS TESTING; MCF-7 CELLS; MOLECULAR TARGETED THERAPY; NEOPLASMS, EXPERIMENTAL; POLYMERS; TREATMENT OUTCOME;

EID: 84877847325     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1606     Document Type: Article

References (32)

1. X. Wang, F. Wei, A. Liu, L. Wang, J. C. Wang, L. Ren, W. Liu, Q. Tu, L. Li, and J. Wang, Cancer stem cell labeling using poly(l-lysine)-modified iron oxide nanoparticles. Biomaterials 33, 3719 (2012).
2. M. Guo, C. Que, C. Wang, X. Liu, H. Yan, and K. Liu, Multi-funtional suparparamagnetic nanocarriers with folate-mediated and Ph-responsive targeting properties for anticancer drug delivery. Biomaterials 32, 185 (2011). Delivered by Publishing T
3. S. S. R. K. Challa and M. Faruq, Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv. drug Deliv. Rev. 63, 789 (2010).
4. R. Rastogi, N. Gulati, R. K. Kotnala, U. Sharma, R. Jayasundar, and V. Koul, Evaluation of folate conjugated pegylated thermosensitive magnetic nanocomposites for tumor imaging and therapy, Colloids Surf., B 82, 160 (2011).
5. N. Lewinski, V. Colvin, and R. Drezek, Cytotoxicity of nanoparticles. Small 4, 26 (2008).
6. J. H. Ke, J. J. Lin, J. R. Carey, J. S. Chen, C. Y. Chen, and L. F. Wang, A specific tumor-targeting magnetofluorescent nanoprobe for dual-modality molecular imaging, Biomaterials 31, 1707 (2009).
7. M. Lattuada and T. A. Hatton, Functionalization of monodisperse magnetic nanoparticles, Langmuir 23, 2158 (2007).
8. A. K. Gupta, and M. Gupta, Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications, Biomaterials 26, 3995 (2005).
9. W. Niu, L. Zhang, M. Pan, and Y. Chen, Preparation of dextran modified superparamagnetic iron oxide nanoparticles based immunoprobes, Appl. Mech. Mat. 138-189, 1089 (2012).
10. H. Arami, Z. Stephen, O. Veiseh, M. Zhang, Chitosan-coated iron oxide nanoparticles for molecular imaging and drug delivery, Adv. Polym. Sci. 243, 163 (2011).
11. B. Gaihre, M. S. Khil, and H. Y. Kim, In vitro anticancer activity of doxorubicin-loaded gelatin-coated magnetic iron oxide nanoparticles, J. Microencapsul. 28, 286 (2011).
12. J. Gautier, E. Munnier, A. Paillard, K. Hervé, L. Douziech-Eyrolles, M. Soucé, P. Dubois, and I. Chourpa, A pharmaceutical study of doxorubicin-loaded PEGylated nanoparticles for magnetic drug targeting, Int. J. Pharm. 423, 16 (2012).
13. Y. H. Ma, S. Y. Wu, T. Wu, Y. J. Chang, M. Y. Hua, and J. P. Chen, Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles, Biomaterials 30, 3343 (2009).
14. P. Zou, Y. Yu, Y. A. Wang, Y. Zhong, A. Welton, C. Galbán, S. Wang, and D. Sun, Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release, Mol. Pharmac. 7, 1974 (2010).
15. 4 nanoparticles-loaded PEG-PLA polymeric vesicles as labels for ultrasensitive immunosensors, Biomaterials 31, 7332 (2010).
16. X. Yang, H. Hong, J.J. Grailer, I.J. Rowland, A. Javadi, and S.A. Hurley, cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging, Biomaterials 32, 4151 (2011).
17. D. B. Geoffrey, L. Alline, C. Yanjin, S. Kyle, EA. Linnea, and A. S. Matthew, Multicomponent folate-targeted magnetoliposomes: Design, characterization, and cellular uptake. Nanomedicine: Nanotechnol. Biol. Med. 7, 797 (2011).
18. X. X. Ying, Y Z. Du, L. H. Hong, H. Yuan, and F. Q. Hu, Magnetic lipid nanoparticles loading doxorubicin for intracellular delivery: Preparation and characteristics. J. Magn. Magn. Mat. 323, 1088 (2011).
19. H. Chi, T. Zhaomin, Z. Yangbo, Z. Xiaofeng, J. Yong, L. Dan, Y Ying, and Z. Shaobing, Magnetic micelles as a potential platform for dual targeted drug delivery in cancer therapy. Int. J. Pharm. 429, 113 (2012).
20. G. Cavallaro, M. Licciardi, G. Pitarresi, and G. Giammona, Folate-Mediated Targeting of Polymers as Components of Colloidal Drug Delivery Systems in Handbook of Drug Targeting and Monitoring, edited by B. Andreev, V. Egorov, Nova Science Publishers, Inc. NY (2010) Ch. 6, pp. 165-178.
21. J. A. Reddy and P. S. Low, Folate-mediated targeting of therapeutic and imaging agents to cancers. Crit. Rev. Ther. Drug Carrier Systems 15, 39 (1998).
22. G. Giammona, B. Carlisi, and S. Palazzo, Reaction of α, β-poly(N-2-hydroxyethyl)-DL aspartamide with derivatives of carboxylic acids. J. Polym. Sci. Pol. Chem. 25, 2813 (1987).
23. R. Mendichi, G. Giammona, G. Cavallaro, and A. S. Giacometti, Molecular characterization of alpha,beta-poly(N-hydroxyethyl)-DL-aspartamide by light scattering and viscometry studies. Polymer 41, 649 (2000).
24. J. Riemer, H. H. Hepken, H. Czerwinska, S. R. Robinson, and R. Dringen, Colorimetric ferrozine-based assay for the quantitation of iron in culture cells. Anal. Biochem. 331, 370 (2004).
25. E. F. Craparo, G. Teresi, M. C. Ognibene, M. P. Casaletto, M. L. Bondì, and G. Cavallaro, Nanoparticles based on novel amphiphilic polyaspartamide copolymers. J. Nanopart. Res. 12, 2629 (2010).
26. G. Cavallaro, S. Scirè, M. Licciardi, M. Ogris, E. Wagner, and G. Giammona, Polyhydroxyethylaspartamide-spermine copolymers: Efficient vectors for gene delivery. J. Control. Release 131, 54 (2008).
27. N. A. Ochekpe, P. O. Olorunfemi, and N. C. Ngwuluka, Nanotechnology and drug delivery part 1: Background and applications. Trop. J. Pharmac. Res. 8, 265 (2009).
28. L. Néel, Théorie du traînage magnétique des ferromagnétiques en grains fins avec applications aux terres cuites. Ann. Geophys. 5, 99 (1949).
29. Q. Song and Z. J. Zhang, Correlation between spin-orbital coupling and the superparamagnetic properties in magnetite and cobalt ferrite spinel nanocrystals. J. Phys. Chem. B 110, 11205 (2006).
30. 3 films. Phys. Rev. B 9, 3891 (1974).
31. M. M. Schieber, Iron oxides and their compounds, In Experimental Magnetochemistry, edited by E. P. Wohlfarth, North-Holland Publishing Company, Amsterdam (1967).
32. A. Palma, L. A. Alvarez, D. Scholz, D. O. Frimannsson, M. Grossi, S.J. Quinn, and D.F. O'Shea, Cellular uptake mediated off/on responsive near-infrared fluorescent nanoparticles. J. Am. Chem. Soc. 133, 19618 (2011).