Age, gender, and earlier opioid requirement associations with the rate of dose escalation in long-term opioid therapy

Journal of Opioid Management

Volumn 9, Issue 2, 2013, Pages 129-138

  Han, Huijun ^a,b   Kass, Philip H ^c   Wilsey, Barth L ^d   Li, Chin Shang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Drug tolerance; Epidemiology; Opioids; Substance abuse

Indexed keywords

MORPHINE;

ADULT; AGE; AGED; ARTICLE; ASSOCIATION; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DOSE ESCALATION; FEMALE; GENDER; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; RETROSPECTIVE STUDY; RISK FACTOR;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; CALIFORNIA; CHRONIC PAIN; DRUG DOSAGE CALCULATIONS; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84877841942     PISSN: 15517489     EISSN: None     Source Type: Journal    
DOI: 10.5055/jom.2012.0154     Document Type: Article

References (53)

1. American Academy of Pain Medicine and American Pain Society: The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society. Clin J Pain. 1997; 13(1): 6-8.
2. American Society of Anesthesiologists: Practice guidelines for chronic pain management. A report by the American Society of Anesthesiologists Task Force on Pain Management, Chronic Pain Section. Anesthesiology. 1997; 86(4): 995-1004.
3. Boudreau D, Von Korff M, Rutter CM, et al.: Trends in long-term opioid therapy for chronic non-cancer pain. Pharmacoepidemiol Drug Saf. 2009; 18(12): 1166-1175.
4. Caudill-Slosberg MA, Schwartz LM, Woloshin S: Office visits and analgesic prescriptions for musculoskeletal pain in US: 1980 vs. 2000. Pain. 2004; 109(3): 514-519. (Pubitemid 38638730)
5. Campbell CI, Weisner C, Leresche L, et al.: Age and gender trends in long-term opioid analgesic use for noncancer pain. Am J Public Health. 2010; 100(12): 2541-2547.
6. Thielke SM, Simoni-Wastila L, Edlund MJ, et al.: Age and sex trends in long-term opioid use in two large American health systems between 2000 and 2005. Pain Med. 2010; 11(2): 248-256.
7. Stewart BL: Myth-Representations of Opioids & Their Risks. 2011. Available at http://updates.pain-topics.org/2011/09/myth-representations-of- opioids-their.html. Accessed November 28, 2011.
8. Breivik H, Collett B, Ventafridda V, et al.: Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment. Eur J Pain. 2006; 10(4): 287-333.
9. Portenoy RK, Foley KM: Chronic use of opioid analgesics in non-malignant pain: Report of 38 cases. Pain. 1986; 25(2): 171-186. (Pubitemid 16121641)
10. Tennant F: Opioid treatment 10-year longevity survey. Final report. Pract Pain Manag. 2010; 10(1): 47-48.
11. Tennant F: A 10-year evaluation of chronic pain patients treated with opioids. Heroin Addict Relat Clin Probl. 2009; 11(1): 31-34.
12. Jensen MK, Thomsen AB, Hojsted J: 10-Year follow-up of chronic non-malignant pain patients: Opioid use, health related quality of life and health care utilization. Eur J Pain. 2006; 10(5): 423-433. (Pubitemid 43786449)
13. Zenz M, Strumpf M, Tryba M: Long-term oral opioid therapy in patients with chronic nonmalignant pain. J Pain Symptom Manage. 1992; 7(2): 69-77.
14. Paice JA, Penn RD, Shott S: Intraspinal morphine for chronic pain: A retrospective, multicenter study. J Pain Symptom Manage. 1996; 11(2): 71-80. (Pubitemid 26073492)
15. Mystakidou K, Parpa E, Tsilika E, et al.: Long-term management of noncancer pain with transdermal therapeutic system-fentanyl. J Pain. 2003; 4(6): 298-306. (Pubitemid 37013020)
16. Hayek SM, Veizi IE, Narouze SN, et al.: Age-dependent intrathecal opioid escalation in chronic noncancer pain patients. Pain Med. 2011; 12(8): 1179-1189.
17. Buntin-Mushock C, Phillip L, Moriyama K, et al.: Age-dependent opioid escalation in chronic pain patients. Anesth Analg. 2005; 100(6): 1740-1745. (Pubitemid 40712733)
18. Dominguez E, Sahinler B, Bassam D, et al.: Predictive value of intrathecal narcotic trials for long-term therapy with implantable drug administration systems in chronic non-cancer pain patients. Pain Pract. 2002; 2(4): 315-325.
19. Cifuentes M, Webster B, Genevay S, et al.: The course of opioid prescribing for a new episode of disabling low back pain: Opioid features and dose escalation. Pain. 2010; 151(1): 22-29.
20. Wilsey BL, Fishman SM, Gilson AM, et al.: Profiling multiple provider prescribing of opioids, benzodiazepines, stimulants, and anorectics. Drug Alcohol Depend. 2010; 112(1-2): 99-106.
21. Streiner DL: The case of the missing data: Methods of dealing with dropouts and other research vagaries. Can J Psychiatry. 2002; 47(1): 68-75.
22. Mallinckrodt CH, Clark WS, David SR: Accounting for dropout bias using mixed-effects models. J Biopharm Stat. 2001; 11(1-2): 9-21. (Pubitemid 32642825)
23. Korff MV, Saunders K, Thomas Ray G, et al.: De facto long-term opioid therapy for noncancer pain. Clin J Pain. 2008; 24(6): 521-527.
24. Weisner CM, Campbell CI, Ray GT, et al.: Trends in prescribed opioid therapy for non-cancer pain for individuals with prior substance use disorders. Pain. 2009; 145(3): 287-293.
25. Herper M: America's most popular drugs: A narcotic painkiller tops Forbes' list of the most prescribed medicines. 2010. Available at: www.forbes.com/2010/05/11/narcotic-painkiller-vicodin-business-healthcare- popular-drugs.html. Accessed August 23, 2012.
26. USFDA: Joint meeting of the Drug Safety and Risk Management Advisory Committee with the Anesthetic and Life Support Drugs Advisory Committee and the Nonprescription Drugs Advisory Committee: Meeting announcement. 2009. Available at: http://www.fda.gov/AdvisoryCommittees/Calendar/ucm143083.htm. Accessed November 15, 2010.
27. USFDA: Organ-specific warnings: internal analgesic, antipyretic, and antirheumatic drug products for over-the-counter human use. 2009. Available at: http://edocket.access.gpo.gov/2009/pdf/E9-9684.pdf. Accessed November 15, 2010.
28. Dunn KM, Saunders KW, Rutter CM, et al.: Opioid prescriptions for chronic pain and overdose: A cohort study. Ann Intern Med. 2010; 152(2): 85-92.
29. Bercovitch M, Adunsky A: Patterns of high-dose morphine use in a home-care hospice service: Should we be afraid of it? Cancer. 2004; 101(6): 1473-1477. (Pubitemid 39180404)
30. Cepeda MS, Etropolski M, Weinstein R, et al.: Dose patterns in commercially insured subjects chronically exposed to opioids: A large cohort study in the United States. BMC Palliat Care. 2010; 9: 14.
31. Akaike H: A new look at the statistical model identification. IEEE Trans Automat Contr. 1974; 19(6): 716-723.
32. Twycross RG: Clinical experience with diamorphine in advanced malignant disease. Int J Clin Pharmacol. 1974; 7(3): 184-198.
33. Collin E, Poulain P, Gauvain-Piquard A, et al.: Is disease progression the major factor in morphine 'tolerance' in cancer pain treatment? Pain. 1993; 55(3): 319-326. (Pubitemid 23350577)
34. Nozaki M, Akera T, Lee CY, et al.: The effects of age on the development of tolerance to and physical dependence on morphine in rats. J Pharmacol Exp Ther. 1975; 192(3): 506-512.
35. Wang Y, Mitchell J, Moriyama K, et al.: Age-dependent morphine tolerance development in the rat. Anesth Analg. 2005; 100(6): 1733-1739. (Pubitemid 40712732)
36. Huidobro JP, Huidobro F: Acute morphine tolerance in new born and young rats. Psychopharmacologia. 1973; 28(1): 27-34.
37. Nicak A, Kohut A: Development of tolerance to morphine and pethidine in rats in dependence on age. Act Nerv Super (Praha). 1978; 20(3): 231-235. (Pubitemid 9082237)
38. Ingram SL, Fossum EN, Morgan MM: Behavioral and electrophysiological evidence for opioid tolerance in adolescent rats. Neuropsychopharmacology. 2007; 32(3): 600-606.
39. Fine PG: Pharmacological management of persistent pain in older patients. Clin J Pain. 2004; 20(4): 220-226.
40. Craft RM, Stratmann JA, Bartok RE, et al.: Sex differences in development of morphine tolerance and dependence in the rat. Psychopharmacology (Berl). 1999; 143(1): 1-7. (Pubitemid 29189987)
41. Baamonde AI, Hidalgo A, Andres-Trelles F: Sex-related differences in the effects of morphine and stress on visceral pain. Neuropharmacology. 1989; 28(9): 967-970. (Pubitemid 19224341)
42. Lipa SM, Kavaliers M: Sex differences in the inhibitory effects of the NMDA antagonist, MK-801, on morphine and stress-induced analgesia. Brain Res Bull. 1990; 24(4): 627-630. (Pubitemid 20161527)
43. Candido J, Lutfy K, Billings B, et al.: Effect of adrenal and sex hormones on opioid analgesia and opioid receptor regulation. Pharmacol Biochem Behav. 1992; 42(4): 685-692.
44. Thornton SR, Wang AF, Smith FL: Characterization of neonatal rat morphine tolerance and dependence. Eur J Pharmacol. 1997; 340(2-3): 161-167. (Pubitemid 28022637)
45. Kasson BG, George R: Endocrine influences on the actions of morphine: IV. Effects of sex and strain. Life Sci. 1984; 34(17): 1627-1634. (Pubitemid 14167891)
46. Thornton SR, Smith FL: Characterization of neonatal rat fentanyl tolerance and dependence. J Pharmacol Exp Ther. 1997; 281(1): 514-521. (Pubitemid 27203110)
47. Back SE, Payne RL, Simpson AN, et al.: Gender and prescription opioids: Findings from the National Survey on Drug Use and Health. Addict Behav. 2010; 35(11): 1001-1007.
48. Bohnert AS, Valenstein M, Bair MJ, et al.: Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA. 2011; 305(13): 1315-1321.
49. Becker WC, Sullivan LE, Tetrault JM, et al.: Non-medical use, abuse and dependence on prescription opioids among U.S. adults: Psychiatric, medical and substance use correlates. Drug Alcohol Depend. 2008; 94(1-3): 38-47.
50. Toblin RL, Mack KA, Perveen G, et al.: A population-based survey of chronic pain and its treatment with prescription drugs. Pain. 2011; 152(6): 1249-1255.
51. Edlund MJ, Steffick D, Hudson T, et al.: Risk factors for clinically recognized opioid abuse and dependence among veterans using opioids for chronic non-cancer pain. Pain. 2007; 129(3): 355-362. (Pubitemid 46754578)
52. Edlund MJ, Martin BC, Fan MY, et al.: Risks for opioid abuse and dependence among recipients of chronic opioid therapy: Results from the TROUP study. Drug Alcohol Depend. 2010; 112(1-2): 90-98.
53. Hall AJ, Logan JE, Toblin RL, et al.: Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA. 2008; 300(22): 2613-2620.