The use of imputed sibling genotypes in sibship-based association analysis: On modeling alternatives, power and model misspecification

Behavior Genetics

Volumn 43, Issue 3, 2013, Pages 254-266

  Minicǎ, Camelia C ^a   Dolan, Conor V ^a,b   Hottenga, Jouke Jan ^a   Willemsen, Gonneke ^a   Vink, Jacqueline M ^a   Boomsma, Dorret I ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Dosage model; Family based imputation; Mixture model; Robustness

Indexed keywords

ACCURACY; ARTICLE; COVARIANCE; FAMILY RELATION; FAMILY STUDY; GENE DOSAGE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC MODEL; GENETIC TRAIT; GENOTYPE; LINEAR SYSTEM; MATHEMATICAL COMPUTING; PHENOTYPE; SIBLING; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STATISTICAL PARAMETERS;

GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SIBLINGS;

EID: 84877831322     PISSN: 00018244     EISSN: 15733297     Source Type: Journal    
DOI: 10.1007/s10519-013-9590-1     Document Type: Article

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