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Volumn 190, Issue 10, 2013, Pages 5102-5109

MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin e2 synthase-2

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA 146A; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E2 SYNTHASE 2; UNCLASSIFIED DRUG;

EID: 84877816217     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202397     Document Type: Article
Times cited : (40)

References (47)
  • 1
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis the plaque and its pathogenesis
    • Frohman, E. M., M. K. Racke, and C. S. Raine. 2006. Multiple sclerosis -the plaque and its pathogenesis. N. Engl. J. Med. 354: 942-955.
    • (2006) N. Engl. J. Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 2
    • 20444430842 scopus 로고    scopus 로고
    • Stem cell and progenitor cell transplantation in multiple sclerosis: The discrepancy between neurobiological attraction and clinical feasibility
    • DOI 10.1016/j.jns.2005.03.007, PII S0022510X05000857, Preserve the Neuron. Brain Atrophy, Axonal Loss, Remyelination and Stem Cells in MS. European Charcot Foundation Symposium
    • Lassmann, H. 2005. Stem cell and progenitor cell transplantation in multiple sclerosis: the discrepancy between neurobiological attraction and clinical feasibility. J. Neurol. Sci. 233: 83-86. (Pubitemid 40804820)
    • (2005) Journal of the Neurological Sciences , vol.233 , Issue.1-2 , pp. 83-86
    • Lassmann, H.1
  • 3
    • 20444423819 scopus 로고    scopus 로고
    • The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders
    • DOI 10.1016/j.jns.2005.03.026, PII S0022510X05000948, Preserve the Neuron. Brain Atrophy, Axonal Loss, Remyelination and Stem Cells in MS. European Charcot Foundation Symposium
    • Pluchino, S., and G. Martino. 2005. The therapeutic use of stem cells for myelin repair in autoimmune demyelinating disorders. J. Neurol. Sci. 233: 117-119. (Pubitemid 40804826)
    • (2005) Journal of the Neurological Sciences , vol.233 , Issue.1-2 , pp. 117-119
    • Pluchino, S.1    Martino, G.2
  • 4
    • 53549100473 scopus 로고    scopus 로고
    • The potential use of stem cells in multiple sclerosis: An overview of the preclinical experience
    • Karussis, D., and I. Kassis. 2008. The potential use of stem cells in multiple sclerosis: an overview of the preclinical experience. Clin. Neurol. Neurosurg. 110: 889-896.
    • (2008) Clin. Neurol. Neurosurg , vol.110 , pp. 889-896
    • Karussis, D.1    Kassis, I.2
  • 5
    • 4544359550 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Isolation and therapeutics
    • DOI 10.1089/scd.2004.13.436
    • Alhadlaq, A., and J. J. Mao. 2004. Mesenchymal stem cells: isolation and therapeutics. Stem Cells Dev. 13: 436-448. (Pubitemid 39223294)
    • (2004) Stem Cells and Development , vol.13 , Issue.4 , pp. 436-448
    • Alhadlaq, A.1    Mao, J.J.2
  • 6
    • 0033818035 scopus 로고    scopus 로고
    • Human bone marrow stromal cell: Coexpression of markers specific for multiple mesenchymal cell lineages
    • Seshi, B., S. Kumar, and D. Sellers. 2000. Human bone marrow stromal cell: coexpression of markers specific for multiple mesenchymal cell lineages. Blood Cells Mol. Dis. 26: 234-246.
    • (2000) Blood Cells Mol. Dis , vol.26 , pp. 234-246
    • Seshi, B.1    Kumar, S.2    Sellers, D.3
  • 7
    • 58149265734 scopus 로고    scopus 로고
    • The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair
    • Arthur, A., A. Zannettino, and S. Gronthos. 2009. The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair. J. Cell. Physiol. 218: 237-245.
    • (2009) J. Cell. Physiol , vol.218 , pp. 237-245
    • Arthur, A.1    Zannettino, A.2    Gronthos, S.3
  • 8
    • 59149093623 scopus 로고    scopus 로고
    • Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program
    • Muruganandan, S., A. A. Roman, and C. J. Sinal. 2009. Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program. Cell. Mol. Life Sci. 66: 236-253.
    • (2009) Cell. Mol. Life Sci , vol.66 , pp. 236-253
    • Muruganandan, S.1    Roman, A.A.2    Sinal, C.J.3
  • 10
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • DOI 10.1126/science.290.5497.1775
    • Brazelton, T. R., F. M. Rossi, G. I. Keshet, and H. M. Blau. 2000. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 290: 1775-1779. (Pubitemid 32004810)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.V.2    Keshet, G.I.3    Blau, H.M.4
  • 11
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • DOI 10.1073/pnas.96.19.10711
    • Kopen, G. C., D. J. Prockop, and D. G. Phinney. 1999. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc. Natl. Acad. Sci. USA 96: 10711-10716. (Pubitemid 29442209)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.19 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 12
    • 51949107296 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
    • Yoo, S.W., S. S. Kim, S. Y. Lee, H. S. Lee, H. S. Kim, Y. D. Lee, and H. Suh-Kim. 2008. Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model. Exp. Mol. Med. 40: 387-397.
    • (2008) Exp. Mol. Med , vol.40 , pp. 387-397
    • Yoo, S.W.1    Kim, S.S.2    Lee, S.Y.3    Lee, H.S.4    Kim, H.S.5    Lee, Y.D.6    Eldar-Finkelman, H.7
  • 13
    • 47249117877 scopus 로고    scopus 로고
    • The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target t cell proliferation but not its effector function
    • Ramasamy, R., C. K. Tong, H. F. Seow, S. Vidyadaran, and F. Dazzi. 2008. The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function. Cell. Immunol. 251: 131-136.
    • (2008) Cell. Immunol , vol.251 , pp. 131-136
    • Ramasamy, R.1    Tong, C.K.2    Seow, H.F.3    Vidyadaran, S.4    Dazzi, F.5
  • 15
    • 37349075167 scopus 로고    scopus 로고
    • Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation
    • DOI 10.1016/j.imlet.2007.10.002, PII S016524780700257X
    • English, K., F. P. Barry, and B. P. Mahon. 2008. Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation. Immunol. Lett. 115: 50-58. (Pubitemid 350298590)
    • (2008) Immunology Letters , vol.115 , Issue.1 , pp. 50-58
    • English, K.1    Barry, F.P.2    Mahon, B.P.3
  • 16
    • 34347371299 scopus 로고    scopus 로고
    • Identification of IL-10 and TGF-β transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human mesenchymal stem cells
    • Nasef, A., A. Chapel, C. Mazurier, S. Bouchet, M. Lopez, N. Mathieu, L. Sensebé, Y. Zhang, N. C. Gorin, D. Thierry, and L. Fouillard. 2007. Identification of IL-10 and TGF-beta transcripts involved in the inhibition of Tlymphocyte proliferation during cell contact with human mesenchymal stem cells. Gene Expr. 13: 217-226. (Pubitemid 47024153)
    • (2007) Gene Expression , vol.13 , Issue.4-5 , pp. 217-226
    • Nasef, A.1    Chapel, A.2    Mazurier, C.3    Bouchet, S.4    Lopez, M.5    Mathieu, N.6    Sensebe, L.7    Zhang, Y.8    Gorin, N.-C.9    Thierry, D.10    Fouillard, L.11
  • 18
    • 49649119417 scopus 로고    scopus 로고
    • Mesenchymal stem cells for graft-versushost disease: Close encounters with t cells
    • Dazzi, F., and F. M. Marelli-Berg. 2008. Mesenchymal stem cells for graft-versushost disease: close encounters with T cells. Eur. J. Immunol. 38: 1479-1482.
    • (2008) Eur J. Immunol , vol.38 , pp. 1479-1482
    • Dazzi, F.1    Marelli-Berg, F.M.2
  • 19
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • DOI 10.1182/blood-2004-04-1559
    • Aggarwal, S., and M. F. Pittenger. 2005. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105: 1815-1822. (Pubitemid 40223708)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 21
    • 77958087116 scopus 로고    scopus 로고
    • Prostaglandin e2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells
    • Yanez, R., A. Oviedo, M. Aldea, J. A. Bueren, and M. L. Lamana. 2010. Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells. Exp. Cell Res. 316: 3109-3123.
    • (2010) Exp. Cell Res , Issue.316 , pp. 3109-3123
    • Yanez, R.1    Oviedo, A.2    Aldea, M.3    Bueren, J.A.4    Lamana, M.L.5
  • 22
    • 0347444723 scopus 로고    scopus 로고
    • Micrornas: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. 2004. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 23
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • DOI 10.1126/science.1064921
    • Lagos-Quintana, M., R. Rauhut, W. Lendeckel, and T. Tuschl. 2001. Identification of novel genes coding for small expressed RNAs. Science 294: 853-858. (Pubitemid 33032103)
    • (2001) Science , vol.294 , Issue.5543 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 24
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-Directed Cleavage of HOXB8 mRNA
    • DOI 10.1126/science.1097434
    • Yekta, S., I. H. Shih, and D. P. Bartel. 2004. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304: 594-596. (Pubitemid 38541919)
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.-H.2    Bartel, D.P.3
  • 25
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • DOI 10.1016/0092-8674(93)90530-4
    • Wightman, B., I. Ha, and G. Ruvkun. 1993. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862. (Pubitemid 24014543)
    • (1993) Cell , vol.75 , Issue.5 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 26
    • 33645119514 scopus 로고    scopus 로고
    • Micrornas direct rapid deadenylation of mrna
    • Wu, L., J. Fan, and J. G. Belasco. 2006. MicroRNAs direct rapid deadenylation of mRNA. Proc. Natl. Acad. Sci. USA 103: 4034-4039.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 4034-4039
    • Wu, L.1    Fan, J.2    Belasco, J.G.3
  • 27
    • 40949114603 scopus 로고    scopus 로고
    • Concise review: MicroRNA expression in multipotent mesenchymal stromal cells
    • DOI 10.1634/stemcells.2007-0625
    • Lakshmipathy, U., and R. P. Hart. 2008. Concise review: microRNA expression in multipotent mesenchymal stromal cells. Stem Cells 26: 356-363. (Pubitemid 351413595)
    • (2008) Stem Cells , vol.26 , Issue.2 , pp. 356-363
    • Lakshmipathy, U.1    Hart, R.P.2
  • 28
    • 67349149082 scopus 로고    scopus 로고
    • Microrna-145 regulates oct4, sox2, and klf4 and represses pluripotency in human embryonic stem cells
    • Xu, N., T. Papagiannakopoulos, G. Pan, J. A. Thomson, and K. S. Kosik. 2009. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137: 647-658.
    • (2009) Cell , vol.137 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 29
    • 0043071544 scopus 로고    scopus 로고
    • Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection
    • DOI 10.1002/jcb.10594
    • Baddoo, M., K. Hill, R. Wilkinson, D. Gaupp, C. Hughes, G. C. Kopen, and D. G. Phinney. 2003. Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection. J. Cell. Biochem. 89: 1235-1249. (Pubitemid 36959389)
    • (2003) Journal of Cellular Biochemistry , vol.89 , Issue.6 , pp. 1235-1249
    • Baddoo, M.1    Hill, K.2    Wilkinson, R.3    Gaupp, D.4    Hughes, C.5    Kopen, G.C.6    Phinney, D.G.7
  • 30
    • 34547120690 scopus 로고    scopus 로고
    • Concise review: Stem cell antigen-1: Expression, function, and enigma
    • DOI 10.1634/stemcells.2006-0644
    • Holmes, C., and W. L. Stanford. 2007. Concise review: stem cell antigen-1: expression, function, and enigma. Stem Cells 25: 1339-1347. (Pubitemid 47106000)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1339-1347
    • Holmes, C.1    Stanford, W.L.2
  • 31
    • 77649274469 scopus 로고    scopus 로고
    • Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development
    • Grajales, L., J. García, K. Banach, and D. L. Geenen. 2010. Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development. J. Mol. Cell. Cardiol. 48: 735-745.
    • (2010) J. Mol. Cell. Cardiol , Issue.48 , pp. 735-745
    • Grajales, L.1    García, J.2    Banach, K.3    Geenen, D.L.4
  • 32
    • 84934438320 scopus 로고    scopus 로고
    • Isolation of mesenchymal stem cells from murine bone marrow by immunodepletion
    • Phinney, D. G. 2008. Isolation of mesenchymal stem cells from murine bone marrow by immunodepletion. Methods Mol. Biol. 449: 171-186.
    • (2008) Methods Mol. Biol , vol.449 , pp. 171-186
    • Phinney, D.G.1
  • 33
    • 33646178285 scopus 로고    scopus 로고
    • A sensitive array for microrna expression profiling (michip) based on locked nucleic acids (lna)
    • Castoldi, M., S. Schmidt, V. Benes, M. Noerholm, A. E. Kulozik, M. W. Hentze, and M. U. Muckenthaler. 2006. A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA). RNA 12: 913-920.
    • (2006) RNA , vol.12 , pp. 913-920
    • Castoldi, M.1    Schmidt, S.2    Benes, V.3    Noerholm, M.4    Kulozik, A.E.5    Hentze, M.W.6    Muckenthaler, M.U.7
  • 34
    • 79953295109 scopus 로고    scopus 로고
    • Immunoregulatory function of bone marrow mesenchymal stem cells in eae depends on their differentiation state and secretion of pge2
    • Matysiak, M., W. Orlowski, M. Fortak-Michalska, A. Jurewicz, and K. Selmaj. 2011. Immunoregulatory function of bone marrow mesenchymal stem cells in EAE depends on their differentiation state and secretion of PGE2. J. Neuroimmunol. 233: 106-111.
    • (2011) J. Neuroimmunol , Issue.233 , pp. 106-111
    • Matysiak, M.1    Orlowski, W.2    Dominguez-Villar, M.3    Jurewicz, A.4    Selmaj, K.5
  • 36
    • 33749059160 scopus 로고    scopus 로고
    • Mirbase: The microrna sequence database
    • Griffiths-Jones, S. 2006. miRBase: the microRNA sequence database. Methods Mol. Biol. 342: 129-138.
    • (2006) Methods Mol. Biol , vol.342 , pp. 129-138
    • Griffiths-Jones, S.1
  • 37
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • Grimson, A., K. K. Farh, W. K. Johnston, P. Garrett-Engele, L. P. Lim, and D. P. Bartel. 2007. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell 27: 91-105. (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 38
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mrnas are conserved targets of micrornas
    • Friedman, R. C., K. K. Farh, C. B. Burge, and D. P. Bartel. 2009. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19: 92-105.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 39
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.org resource: Targets and expression
    • DOI 10.1093/nar/gkm995
    • Betel D., M. Wilson, A. Gabow, D. Marks, and C. Sander. 2008. microRNA target predictions: the microRNA.org resource: targets and expression. Nucleic Acids Res. 36(Database Issue): D149-D153. (Pubitemid 351149712)
    • (2008) Nucleic Acids Research , vol.36 , Issue.SUPPL. 1
    • Betel, D.1    Wilson, M.2    Gabow, A.3    Marks, D.S.4    Sander, C.5
  • 45
    • 0034693050 scopus 로고    scopus 로고
    • Molecular identification of cytosolic prostaglandin e2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin e2 biosynthesis
    • Tanioka, T., Y. Nakatani, N. Semmyo, M. Murakami, and I. Kudo. 2000. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J. Biol. Chem. 275: 32775-32782.
    • (2000) J. Biol. Chem , vol.275 , pp. 32775-32782
    • Tanioka, T.1    Nakatani, Y.2    Semmyo, N.3    Murakami, M.4    Kudo, I.5
  • 47
    • 0034692689 scopus 로고    scopus 로고
    • Regulation of prostaglandin e2 biosynthesis by inducible membrane-Associated prostaglandin e2 synthase that acts in concert with cyclooxygenase-2
    • Murakami, M., H. Naraba, T. Tanioka, N. Semmyo, Y. Nakatani, F. Kojima, T. Ikeda, M. Fueki, A. Ueno, S. Oh, and I. Kudo. 2000. Regulation of prostaglandin E2 biosynthesis by inducible membrane-Associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J. Biol. Chem. 275: 32783-32792.
    • (2000) J. Biol. Chem , vol.275 , pp. 32783-32792
    • Murakami, M.1    Naraba, H.2    Tanioka, T.3    Semmyo, N.4    Nakatani, Y.5    Kojima, F.6    Ikeda, T.7    Fueki, M.8    Ueno, A.9    Oh, S.10    Kudo, I.11


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