메뉴 건너뛰기




Volumn 81, Issue 6, 2013, Pages 2028-2042

Infection with francisella tularensis lvs clpb leads to an altered yet protective immune response

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL VACCINE; GAMMA INTERFERON; INTERLEUKIN 17;

EID: 84877814587     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00207-13     Document Type: Article
Times cited : (28)

References (48)
  • 1
    • 71449102798 scopus 로고    scopus 로고
    • Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development
    • Pechous RD, McCarthy TR, Zahrt TC. 2009. Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development. Microbiol. Mol. Biol. Rev. 73:684-711.
    • (2009) Microbiol. Mol. Biol. Rev. , vol.73 , pp. 684-711
    • Pechous, R.D.1    McCarthy, T.R.2    Zahrt, T.C.3
  • 5
    • 65549117835 scopus 로고    scopus 로고
    • Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model
    • doi:10.1371/journal.pone.0005463
    • Kadzhaev K, Zingmark C, Golovliov I, Bolanowski M, Shen H, Conlan W, Sjostedt A. 2009. Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model. PLoS One 4:e5463. doi:10.1371/journal.pone.0005463.
    • (2009) PLoS One , vol.4
    • Kadzhaev, K.1    Zingmark, C.2    Golovliov, I.3    Bolanowski, M.4    Shen, H.5    Conlan, W.6    Sjostedt, A.7
  • 6
    • 34249868441 scopus 로고    scopus 로고
    • Genomewide identification of Francisella tularensis virulence determinants
    • Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. 2007. Genomewide identification of Francisella tularensis virulence determinants. Infect. Immun. 75:3089-3101.
    • (2007) Infect. Immun. , vol.75 , pp. 3089-3101
    • Su, J.1    Yang, J.2    Zhao, D.3    Kawula, T.H.4    Banas, J.A.5    Zhang, J.R.6
  • 9
    • 0037963150 scopus 로고    scopus 로고
    • Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studies
    • Conlan JW, Chen W, Shen H, Webb A, KuoLee R. 2003. Experimental tularemia in mice challenged by aerosol or intradermally with virulent strains of Francisella tularensis: bacteriologic and histopathologic studies. Microb. Pathog. 34:239-248.
    • (2003) Microb. Pathog. , vol.34 , pp. 239-248
    • Conlan, J.W.1    Chen, W.2    Shen, H.3    Webb, A.4    KuoLee, R.5
  • 10
    • 57349174394 scopus 로고    scopus 로고
    • Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112
    • Hall JD, Woolard MD, Gunn BM, Craven RR, Taft-Benz S, Frelinger JA, Kawula TH. 2008. Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112. Infect. Immun. 76:5843-5852.
    • (2008) Infect. Immun. , vol.76 , pp. 5843-5852
    • Hall, J.D.1    Woolard, M.D.2    Gunn, B.M.3    Craven, R.R.4    Taft-Benz, S.5    Frelinger, J.A.6    Kawula, T.H.7
  • 11
    • 27744547036 scopus 로고    scopus 로고
    • Francisella tularensis induces aberrant activation of pulmonary dendritic cells
    • Bosio CM, Dow SW. 2005. Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J. Immunol. 175:6792-6801.
    • (2005) J. Immunol. , vol.175 , pp. 6792-6801
    • Bosio, C.M.1    Dow, S.W.2
  • 13
    • 33947702199 scopus 로고    scopus 로고
    • Active suppression of the pulmonary immune response by Francisella tularensis Schu4
    • Bosio CM, Bielefeldt-Ohmann H, Belisle JT. 2007. Active suppression of the pulmonary immune response by Francisella tularensis Schu4. J. Immunol. 178:4538-4547.
    • (2007) J. Immunol. , vol.178 , pp. 4538-4547
    • Bosio, C.M.1    Bielefeldt-Ohmann, H.2    Belisle, J.T.3
  • 14
    • 84875308050 scopus 로고    scopus 로고
    • The Francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation
    • doi:10.3389/fmicb.2010.00138
    • Chong A, Celli J. 2010. The Francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation. Front. Microbiol. 1:138. doi:10.3389/fmicb.2010.00138.
    • (2010) Front. Microbiol. , vol.1 , pp. 138
    • Chong, A.1    Celli, J.2
  • 15
    • 0030443350 scopus 로고    scopus 로고
    • Loss of either CD4+ or CD8+T cells does not affect the magnitude of protective immunity to an intracellular pathogen, Francisella tularensis strain LVS
    • Yee D, Rhinehart-Jones TR, Elkins KL. 1996. Loss of either CD4+ or CD8+T cells does not affect the magnitude of protective immunity to an intracellular pathogen, Francisella tularensis strain LVS. J. Immunol. 157: 5042-5048.
    • (1996) J. Immunol. , vol.157 , pp. 5042-5048
    • Yee, D.1    Rhinehart-Jones, T.R.2    Elkins, K.L.3
  • 16
    • 33646472970 scopus 로고    scopus 로고
    • Myeloid differentiation factor-88 (MyD88) is essential for control of primary in vivo Francisella tularensis LVS infection, but not for control of intra-macrophage bacterial replication
    • Collazo CM, Sher A, Meierovics AI, Elkins KL. 2006. Myeloid differentiation factor-88 (MyD88) is essential for control of primary in vivo Francisella tularensis LVS infection, but not for control of intra-macrophage bacterial replication. Microbes Infect. 8:779-790.
    • (2006) Microbes Infect. , vol.8 , pp. 779-790
    • Collazo, C.M.1    Sher, A.2    Meierovics, A.I.3    Elkins, K.L.4
  • 17
    • 0026571327 scopus 로고
    • In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies
    • Leiby DA, Fortier AH, Crawford RM, Schreiber RD, Nacy CA. 1992. In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies. Infect. Immun. 60:84-89.
    • (1992) Infect. Immun. , vol.60 , pp. 84-89
    • Leiby, D.A.1    Fortier, A.H.2    Crawford, R.M.3    Schreiber, R.D.4    Nacy, C.A.5
  • 18
    • 0024933552 scopus 로고
    • The requirement for gamma interferon in resistance of mice to experimental tularemia
    • Anthony LS, Ghadirian E, Nestel FP, Kongshavn PA. 1989. The requirement for gamma interferon in resistance of mice to experimental tularemia. Microb. Pathog. 7:421-428.
    • (1989) Microb. Pathog. , vol.7 , pp. 421-428
    • Anthony, L.S.1    Ghadirian, E.2    Nestel, F.P.3    Kongshavn, P.A.4
  • 19
    • 46249101937 scopus 로고    scopus 로고
    • Respiratory Francisella tularensis live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells
    • Woolard MD, Hensley LL, Kawula TH, Frelinger JA. 2008. Respiratory Francisella tularensis live vaccine strain infection induces Th17 cells and prostaglandin E2, which inhibits generation of gamma interferon-positive T cells. Infect. Immun. 76:2651-2659.
    • (2008) Infect. Immun. , vol.76 , pp. 2651-2659
    • Woolard, M.D.1    Hensley, L.L.2    Kawula, T.H.3    Frelinger, J.A.4
  • 21
    • 77955285620 scopus 로고    scopus 로고
    • The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis
    • doi:10.1371/journal.pone.0011176
    • Markel G, Bar-Haim E, Zahavy E, Cohen H, Cohen O, Shafferman A, Velan B. 2010. The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis. PLoS One 5:e11176. doi:10.1371/journal.pone.0011176.
    • (2010) PLoS One , vol.5
    • Markel, G.1    Bar-Haim, E.2    Zahavy, E.3    Cohen, H.4    Cohen, O.5    Shafferman, A.6    Velan, B.7
  • 23
    • 39849093588 scopus 로고    scopus 로고
    • The heat-shock protein ClpB of Francisella tularensis is involved in stress tolerance and is required for multiplication in target organs of infected mice
    • Meibom KL, Dubail I, Dupuis M, Barel M, Lenco J, Stulik J, Golovliov I, Sjostedt A, Charbit A. 2008. The heat-shock protein ClpB of Francisella tularensis is involved in stress tolerance and is required for multiplication in target organs of infected mice. Mol. Microbiol. 67:1384-1401.
    • (2008) Mol. Microbiol. , vol.67 , pp. 1384-1401
    • Meibom, K.L.1    Dubail, I.2    Dupuis, M.3    Barel, M.4    Lenco, J.5    Stulik, J.6    Golovliov, I.7    Sjostedt, A.8    Charbit, A.9
  • 24
    • 75249102515 scopus 로고    scopus 로고
    • Differential ability of novel attenuated targeted deletion mutants of Francisella tularensis subspecies tularensis strain SCHU S4 to protect mice against aerosol challenge with virulent bacteria: effects of host background and route of immunization
    • Conlan JW, Shen H, Golovliov I, Zingmark C, Oyston PC, Chen W, House RV, Sjostedt A. 2010. Differential ability of novel attenuated targeted deletion mutants of Francisella tularensis subspecies tularensis strain SCHU S4 to protect mice against aerosol challenge with virulent bacteria: effects of host background and route of immunization. Vaccine 28:1824-1831.
    • (2010) Vaccine , vol.28 , pp. 1824-1831
    • Conlan, J.W.1    Shen, H.2    Golovliov, I.3    Zingmark, C.4    Oyston, P.C.5    Chen, W.6    House, R.V.7    Sjostedt, A.8
  • 25
    • 84860999978 scopus 로고    scopus 로고
    • BALB/c mice, but not C57BL/6 mice immunized with a DeltaclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: association of protection with post-vaccination and post-challenge immune responses
    • Twine S, Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W. 2012. BALB/c mice, but not C57BL/6 mice immunized with a DeltaclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: association of protection with post-vaccination and post-challenge immune responses. Vaccine 30: 3634-3645.
    • (2012) Vaccine , vol.30 , pp. 3634-3645
    • Twine, S.1    Shen, H.2    Harris, G.3    Chen, W.4    Sjostedt, A.5    Ryden, P.6    Conlan, W.7
  • 26
    • 0000695637 scopus 로고
    • Evaluation of live tularemia vaccine prepared in a chemically defined medium
    • Chamberlain RE. 1965. Evaluation of live tularemia vaccine prepared in a chemically defined medium. Appl. Microbiol. 13:232-235.
    • (1965) Appl. Microbiol. , vol.13 , pp. 232-235
    • Chamberlain, R.E.1
  • 28
    • 33846928937 scopus 로고    scopus 로고
    • Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response
    • Woolard MD, Wilson JE, Hensley LL, Jania LA, Kawula TH, Drake JR, Frelinger JA. 2007. Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response. J. Immunol. 178:2065-2074.
    • (2007) J. Immunol. , vol.178 , pp. 2065-2074
    • Woolard, M.D.1    Wilson, J.E.2    Hensley, L.L.3    Jania, L.A.4    Kawula, T.H.5    Drake, J.R.6    Frelinger, J.A.7
  • 29
    • 33644763937 scopus 로고    scopus 로고
    • The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display
    • Porter BB, Harty JT. 2006. The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display. Infect. Immun. 74:1528-1536.
    • (2006) Infect. Immun. , vol.74 , pp. 1528-1536
    • Porter, B.B.1    Harty, J.T.2
  • 30
    • 9144224291 scopus 로고    scopus 로고
    • Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells
    • Williams MA, Bevan MJ. 2004. Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells. J. Immunol. 173:6694-6702.
    • (2004) J. Immunol. , vol.173 , pp. 6694-6702
    • Williams, M.A.1    Bevan, M.J.2
  • 31
    • 0035873191 scopus 로고    scopus 로고
    • Cutting edge: antigen-independent CD8 T cell proliferation
    • Wong P, Pamer EG. 2001. Cutting edge: antigen-independent CD8 T cell proliferation. J. Immunol. 166:5864-5868.
    • (2001) J. Immunol. , vol.166 , pp. 5864-5868
    • Wong, P.1    Pamer, E.G.2
  • 32
    • 84859724534 scopus 로고    scopus 로고
    • DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity
    • doi:10.1371/journal .pone.0034639
    • Broms JE, Meyer L, Lavander M, Larsson P, Sjostedt A. 2012. DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity. PLoS One 7:e34639. doi:10.1371/journal .pone.0034639.
    • (2012) PLoS One , vol.7
    • Broms, J.E.1    Meyer, L.2    Lavander, M.3    Larsson, P.4    Sjostedt, A.5
  • 33
    • 0242334128 scopus 로고    scopus 로고
    • Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen: protection varies depending on pathogen virulence, route of exposure, and host genetic background
    • Chen W, Shen H, Webb A, KuoLee R, Conlan JW. 2003. Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen: protection varies depending on pathogen virulence, route of exposure, and host genetic background. Vaccine 21:3690-3700.
    • (2003) Vaccine , vol.21 , pp. 3690-3700
    • Chen, W.1    Shen, H.2    Webb, A.3    KuoLee, R.4    Conlan, J.W.5
  • 34
    • 84857065835 scopus 로고    scopus 로고
    • A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy
    • doi:10.1371/journal.pone.0031172
    • Schmitt DM, O'Dee DM, Horzempa J, Carlson PE, Jr, Russo BC, Bales JM, Brown MJ, Nau GJ. 2012. A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy. PLoS One 7:e31172. doi:10.1371/journal.pone.0031172.
    • (2012) PLoS One , vol.7
    • Schmitt, D.M.1    O'Dee, D.M.2    Horzempa, J.3    Carlson Jr., P.E.4    Russo, B.C.5    Bales, J.M.6    Brown, M.J.7    Nau, G.J.8
  • 35
    • 84875891706 scopus 로고    scopus 로고
    • Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages
    • doi:10.3389/fmicb.2013.00016
    • Woolard MD, Barrigan LM, Fuller JR, Buntzman AS, Bryan J, Manoil C, Kawula TH, Frelinger JA. 2013. Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages. Front. Microbiol. 4:16. doi:10.3389/fmicb.2013.00016.
    • (2013) Front. Microbiol. , vol.4 , pp. 16
    • Woolard, M.D.1    Barrigan, L.M.2    Fuller, J.R.3    Buntzman, A.S.4    Bryan, J.5    Manoil, C.6    Kawula, T.H.7    Frelinger, J.A.8
  • 37
    • 0037167471 scopus 로고    scopus 로고
    • The identification of five genetic loci of Francisella novicida associated with intracellular growth
    • Gray CG, Cowley SC, Cheung KK, Nano FE. 2002. The identification of five genetic loci of Francisella novicida associated with intracellular growth. FEMS Microbiol. Lett. 215:53-56.
    • (2002) FEMS Microbiol. Lett. , vol.215 , pp. 53-56
    • Gray, C.G.1    Cowley, S.C.2    Cheung, K.K.3    Nano, F.E.4
  • 38
    • 33748028835 scopus 로고    scopus 로고
    • Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge
    • Tempel R, Lai XH, Crosa L, Kozlowicz B, Heffron F. 2006. Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge. Infect. Immun. 74:5095-5105.
    • (2006) Infect. Immun. , vol.74 , pp. 5095-5105
    • Tempel, R.1    Lai, X.H.2    Crosa, L.3    Kozlowicz, B.4    Heffron, F.5
  • 39
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL- 12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • Kalinski P, Vieira PL, Schuitemaker JH, de Jong EC, Kapsenberg ML. 2001. Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL- 12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 97:3466-3469.
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.3    de Jong, E.C.4    Kapsenberg, M.L.5
  • 40
    • 13544251389 scopus 로고    scopus 로고
    • Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway
    • Schnurr M, Toy T, Shin A, Wagner M, Cebon J, Maraskovsky E. 2005. Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. Blood 105:1582-1589.
    • (2005) Blood , vol.105 , pp. 1582-1589
    • Schnurr, M.1    Toy, T.2    Shin, A.3    Wagner, M.4    Cebon, J.5    Maraskovsky, E.6
  • 41
    • 9444244401 scopus 로고    scopus 로고
    • Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells
    • Sheibanie AF, Tadmori I, Jing H, Vassiliou E, Ganea D. 2004. Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 18:1318-1320.
    • (2004) FASEB J. , vol.18 , pp. 1318-1320
    • Sheibanie, A.F.1    Tadmori, I.2    Jing, H.3    Vassiliou, E.4    Ganea, D.5
  • 42
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • Hunter CA. 2005. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 5:521-531.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 521-531
    • Hunter, C.A.1
  • 43
    • 33747058216 scopus 로고    scopus 로고
    • A camel passes through the eye of a needle: protein unfolding activity of Clp ATPases
    • Zolkiewski M. 2006. A camel passes through the eye of a needle: protein unfolding activity of Clp ATPases. Mol. Microbiol. 61:1094-1100.
    • (2006) Mol. Microbiol. , vol.61 , pp. 1094-1100
    • Zolkiewski, M.1
  • 44
    • 1142298585 scopus 로고    scopus 로고
    • clpB, a novel member of the Listeria monocytogenes CtsR regulon, is involved in virulence but not in general stress tolerance
    • Chastanet A, Derre I, Nair S, Msadek T. 2004. clpB, a novel member of the Listeria monocytogenes CtsR regulon, is involved in virulence but not in general stress tolerance. J. Bacteriol. 186:1165-1174.
    • (2004) J. Bacteriol. , vol.186 , pp. 1165-1174
    • Chastanet, A.1    Derre, I.2    Nair, S.3    Msadek, T.4
  • 45
    • 80052307960 scopus 로고    scopus 로고
    • Inactivation of clpB in the pathogen Leptospira interrogans reduces virulence and resistance to stress conditions
    • Lourdault K, Cerqueira GM, Wunder EA, Jr, Picardeau M. 2011. Inactivation of clpB in the pathogen Leptospira interrogans reduces virulence and resistance to stress conditions. Infect. Immun. 79:3711-3717.
    • (2011) Infect. Immun. , vol.79 , pp. 3711-3717
    • Lourdault, K.1    Cerqueira, G.M.2    Wunder Jr., E.A.3    Picardeau, M.4
  • 46
    • 38949159752 scopus 로고    scopus 로고
    • Role of the Clp system in stress tolerance, biofilm formation, and intracellular invasion in Porphyromonas gingivalis
    • Capestany CA, Tribble GD, Maeda K, Demuth DR, Lamont RJ. 2008. Role of the Clp system in stress tolerance, biofilm formation, and intracellular invasion in Porphyromonas gingivalis. J. Bacteriol. 190:1436-1446.
    • (2008) J. Bacteriol. , vol.190 , pp. 1436-1446
    • Capestany, C.A.1    Tribble, G.D.2    Maeda, K.3    Demuth, D.R.4    Lamont, R.J.5
  • 47
    • 55849145095 scopus 로고    scopus 로고
    • Characterization of a unique ClpB protein of Mycoplasma pneumoniae and its impact on growth
    • Kannan TR, Musatovova O, Gowda P, Baseman JB. 2008. Characterization of a unique ClpB protein of Mycoplasma pneumoniae and its impact on growth. Infect. Immun. 76:5082-5092.
    • (2008) Infect. Immun. , vol.76 , pp. 5082-5092
    • Kannan, T.R.1    Musatovova, O.2    Gowda, P.3    Baseman, J.B.4
  • 48
    • 0031900977 scopus 로고    scopus 로고
    • Identification of Salmonella typhimurium genes required for colonization of the chicken alimentary tract and for virulence in newly hatched chicks
    • Turner AK, Lovell MA, Hulme SD, Zhang-Barber L, Barrow PA. 1998. Identification of Salmonella typhimurium genes required for colonization of the chicken alimentary tract and for virulence in newly hatched chicks. Infect. Immun. 66:2099-2106.
    • (1998) Infect. Immun. , vol.66 , pp. 2099-2106
    • Turner, A.K.1    Lovell, M.A.2    Hulme, S.D.3    Zhang-Barber, L.4    Barrow, P.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.