Heparin-binding correlates with increased efficiency of AAV1-and AAV6-mediated transduction of striated muscle, but negatively impacts CNS transduction

Gene Therapy

Volumn 20, Issue 5, 2013, Pages 497-503

  Arnett, A L H ^a,b   Beutler, L R ^b   Quintana, A ^a   Allen, J ^a   Finn, E ^a   Palmiter, R D ^a,b   Chamberlain, J S ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARIN;

ARTICLE; CENTRAL NERVOUS SYSTEM; DRUG BINDING; GENE EXPRESSION; GENETIC TRANSDUCTION; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; VIRUS CAPSID;

ANIMALS; CAPSID; DEPENDOVIRUS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HEPARAN SULFATE PROTEOGLYCANS; HEPARIN; HUMANS; MICE; MUSCLE, STRIATED; TRANSDUCTION, GENETIC; TROPISM;

ADENO-ASSOCIATED VIRUS; MIRIDAE;

EID: 84877746944     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2012.60     Document Type: Article

References (0)