메뉴 건너뛰기




Volumn 6, Issue 3, 2013, Pages 299-309

Platelet biology and receptor pathways

Author keywords

Aggregation; Coagulation; Membrane receptors; Platelet

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ALX 0081; ANTICOAGULANT AGENT; ATOPAXAR; CLOPIDOGREL; COLLAGEN RECEPTOR ANTAGONIST; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; GLYCOPROTEIN VI ANTAGONIST; GLYCOPROTEINIB ANTIBODY; INTEGRIN; INTEGRIN ALPHA2BETA1 ANTAGONIST; MICRORNA; MONOCLONAL ANTIBODY JAQ1; PLACEBO; PLATELET DERIVED GROWTH FACTOR; PROSTAGLANDIN SYNTHASE; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR ANTAGONIST; PURINERGIC RECEPTOR; THROMBOCYTE RECEPTOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; TIROFIBAN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR ANTIBODY; VORAPAXAR;

EID: 84877742479     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-012-9445-9     Document Type: Article
Times cited : (62)

References (83)
  • 1
    • 25444437966 scopus 로고    scopus 로고
    • Platelets: Physiology and biochemistry
    • 16149014 10.1055/s-2005-916671 1:CAS:528:DC%2BD2MXhtFeis7jP
    • Jurk, K., & Kehrel, B. E. (2005). Platelets: Physiology and biochemistry. Seminars in Thrombosis and Hemostasis, 31(4), 381-392.
    • (2005) Seminars in Thrombosis and Hemostasis , vol.31 , Issue.4 , pp. 381-392
    • Jurk, K.1    Kehrel, B.E.2
  • 2
    • 28344454939 scopus 로고    scopus 로고
    • Mechanisms of thrombopoiesis
    • 16102038 10.1111/j.1538-7836.2005.01426.x 1:CAS:528:DC%2BD2MXpsFKjsr0%3D
    • Schulze, H., & Shivdasani, R. A. (2005). Mechanisms of thrombopoiesis. Journal of Thrombosis and Haemostasis, 3(8), 1717-1724.
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.8 , pp. 1717-1724
    • Schulze, H.1    Shivdasani, R.A.2
  • 3
    • 0034902812 scopus 로고    scopus 로고
    • The platelet release reaction: Granules' constituents, secretion and functions
    • 11487378 10.1080/09537100120068170 1:CAS:528:DC%2BD3MXlslKmu78%3D
    • Rendu, F., & Brohard-Bohn, B. (2001). The platelet release reaction: Granules' constituents, secretion and functions. Platelets, 12, 261-273.
    • (2001) Platelets , vol.12 , pp. 261-273
    • Rendu, F.1    Brohard-Bohn, B.2
  • 4
    • 0025743588 scopus 로고
    • The platelet open canalicular system: A final common pathway
    • 1760557 1:STN:280:DyaK387gtlajsA%3D%3D
    • Escolar, G., & White, J. G. (1991). The platelet open canalicular system: A final common pathway. Blood Cells, 17, 467-485.
    • (1991) Blood Cells , vol.17 , pp. 467-485
    • Escolar, G.1    White, J.G.2
  • 5
    • 0027748236 scopus 로고
    • The platelet cytoskeleton
    • 8165606 1:CAS:528:DyaK2cXisVSru7s%3D
    • Fox, J. E. (1993). The platelet cytoskeleton. Thrombosis and Haemostasis, 70, 884-893.
    • (1993) Thrombosis and Haemostasis , vol.70 , pp. 884-893
    • Fox, J.E.1
  • 6
    • 0033165875 scopus 로고    scopus 로고
    • Platelet dense granules: Structure, function and implications for haemostasis
    • 10403682 10.1016/S0049-3848(99)00015-8 1:CAS:528:DyaK1MXksVSrtLk%3D
    • McNicol, A., & Israels, S. J. (1999). Platelet dense granules: Structure, function and implications for haemostasis. Thrombosis Research, 95, 1-18.
    • (1999) Thrombosis Research , vol.95 , pp. 1-18
    • McNicol, A.1    Israels, S.J.2
  • 7
    • 0032055178 scopus 로고    scopus 로고
    • Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules
    • 9516129 1:CAS:528:DyaK1cXitF2hsrg%3D
    • Heijnen, H. F., Debili, N., Vainchencker, W., Breton-Gorius, J., Geuze, H. J., & Sixma, J. J. (1998). Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules. Blood, 91(7), 2313-2325.
    • (1998) Blood , vol.91 , Issue.7 , pp. 2313-2325
    • Heijnen, H.F.1    Debili, N.2    Vainchencker, W.3    Breton-Gorius, J.4    Geuze, H.J.5    Sixma, J.J.6
  • 8
    • 0027404805 scopus 로고
    • Platelet alpha-granules
    • 8467233 10.1016/0268-960X(93)90024-X 1:STN:280:DyaK3s3it1Ojtg%3D%3D
    • Harrison, P., & Cramer, E. M. (1993). Platelet alpha-granules. Blood Reviews, 7, 52-62.
    • (1993) Blood Reviews , vol.7 , pp. 52-62
    • Harrison, P.1    Cramer, E.M.2
  • 9
    • 79953150620 scopus 로고    scopus 로고
    • Platelets and the immune continuum
    • 21436837 10.1038/nri2956 1:CAS:528:DC%2BC3MXjvVOhu7s%3D
    • Semple, J. W., Italiano, J. E., Jr., & Freedman, J. (2011). Platelets and the immune continuum. Nature Reviews Immunology, 11(4), 264-274.
    • (2011) Nature Reviews Immunology , vol.11 , Issue.4 , pp. 264-274
    • Semple, J.W.1    Italiano, Jr.J.E.2    Freedman, J.3
  • 10
    • 77950635286 scopus 로고    scopus 로고
    • Basic principles of platelet biology and clinical implications
    • 20197627 10.1253/circj.CJ-09-0982 1:CAS:528:DC%2BC3cXls1Sksb0%3D
    • Angiolillo, D. J., Ueno, M., & Goto, S. (2010). Basic principles of platelet biology and clinical implications. Circulation Journal, 74, 597-607.
    • (2010) Circulation Journal , vol.74 , pp. 597-607
    • Angiolillo, D.J.1    Ueno, M.2    Goto, S.3
  • 14
    • 0025732428 scopus 로고
    • The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress
    • 2010539 10.1172/JCI115124 1:CAS:528:DyaK3MXitVCntr8%3D
    • Ikeda, Y., Handa, M., Kawano, K., Kamata, T., Murata, M., Araki, Y., et al. (1991). The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress. The Journal of Clinical Investigation, 87(4), 1234-1240.
    • (1991) The Journal of Clinical Investigation , vol.87 , Issue.4 , pp. 1234-1240
    • Ikeda, Y.1    Handa, M.2    Kawano, K.3    Kamata, T.4    Murata, M.5    Araki, Y.6
  • 15
    • 33845268866 scopus 로고    scopus 로고
    • A single high-affinity binding site for von Willebrand Factor in collagen III, identified using synthetic triple-helical peptides
    • 16912226 10.1182/blood-2006-03-011965 1:CAS:528:DC%2BD28Xht1Kgs7zN
    • Lisman, T., Raynal, N., Groeneveld, D., Maddox, B., Peachey, A. R., Huizinga, E. G., et al. (2006). A single high-affinity binding site for von Willebrand Factor in collagen III, identified using synthetic triple-helical peptides. Blood, 108, 3753-3756.
    • (2006) Blood , vol.108 , pp. 3753-3756
    • Lisman, T.1    Raynal, N.2    Groeneveld, D.3    Maddox, B.4    Peachey, A.R.5    Huizinga, E.G.6
  • 16
    • 0345412698 scopus 로고    scopus 로고
    • Kinetics of GPIb alpha-vWF-A1 tether bond under flow: Effect of GPIb alpha mutations on the association and dissociation rates
    • 14645097 10.1016/S0006-3495(03)74822-X 1:CAS:528:DC%2BD3sXpvVamtrk%3D
    • Kumar, R. A., Dong, J. F., Thaggard, J. A., Cruz, M. A., Lopez, J. A., & McIntire, L. V. (2003). Kinetics of GPIb alpha-vWF-A1 tether bond under flow: Effect of GPIb alpha mutations on the association and dissociation rates. Biophysical Journal, 85, 4099-4109.
    • (2003) Biophysical Journal , vol.85 , pp. 4099-4109
    • Kumar, R.A.1    Dong, J.F.2    Thaggard, J.A.3    Cruz, M.A.4    Lopez, J.A.5    McIntire, L.V.6
  • 17
    • 0032483550 scopus 로고    scopus 로고
    • Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
    • 9741630 10.1016/S0092-8674(00)81607-4 1:CAS:528:DyaK1cXmtVWksrg%3D
    • Savage, B., Almus-Jacobs, F., & Ruggeri, Z. M. (1998). Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. Cell, 94, 657-666.
    • (1998) Cell , vol.94 , pp. 657-666
    • Savage, B.1    Almus-Jacobs, F.2    Ruggeri, Z.M.3
  • 18
    • 27744564167 scopus 로고    scopus 로고
    • Two functional active conformations of the integrin alpha 2 beta 1, depending on activation condition and cell type
    • 16103112 10.1074/jbc.M508148200
    • Van de Walle, G. R., Vanhoorelbeke, K., Majer, Z., Illyes, E., Baert, J., Pareyn, I., et al. (2005). Two functional active conformations of the integrin alpha 2 beta 1, depending on activation condition and cell type. Journal of Biological Chemistry, 280, 36873-36882.
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 36873-36882
    • Van De Walle, G.R.1    Vanhoorelbeke, K.2    Majer, Z.3    Illyes, E.4    Baert, J.5    Pareyn, I.6
  • 19
    • 0038494921 scopus 로고    scopus 로고
    • Platelet-collagen interaction: Is GPVI the central receptor?
    • 12649139 10.1182/blood-2002-12-3882 1:CAS:528:DC%2BD3sXlslGitrw%3D
    • Nieswandt, B., & Watson, S. P. (2003). Platelet-collagen interaction: Is GPVI the central receptor? Blood, 102, 449-461.
    • (2003) Blood , vol.102 , pp. 449-461
    • Nieswandt, B.1    Watson, S.P.2
  • 20
    • 0037050027 scopus 로고    scopus 로고
    • Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface
    • 11805836 10.1038/415175a 1:CAS:528:DC%2BD38XmsVOlsw%3D%3D
    • Dale, G. L., Friese, P., Batar, P., et al. (2002). Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surface. Nature, 415, 175-179.
    • (2002) Nature , vol.415 , pp. 175-179
    • Dale, G.L.1    Friese, P.2    Batar, P.3
  • 21
    • 0025821449 scopus 로고
    • Monoclonal antibodies to platelet glycoprotein IIb/IIIa as antithrombotic agents
    • 2024884 10.1111/j.1749-6632.1991.tb43703.x 1:CAS:528:DyaK3MXmsFensbY%3D
    • Coller, B. S., Scudder, L. E., Beer, J., Gold, H. K., Folts, J. D., Cavagnaro, J., et al. (1991). Monoclonal antibodies to platelet glycoprotein IIb/IIIa as antithrombotic agents. Annals of the New York Academy of Sciences, 614, 193-213.
    • (1991) Annals of the New York Academy of Sciences , vol.614 , pp. 193-213
    • Coller, B.S.1    Scudder, L.E.2    Beer, J.3    Gold, H.K.4    Folts, J.D.5    Cavagnaro, J.6
  • 22
    • 0032497918 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa integrin blockade
    • 9843473 10.1161/01.CIR.98.23.2629 1:CAS:528:DyaK1MXlvVCi
    • Madan, M., Berkowitz, S. D., & Tcheng, J. E. (1998). Glycoprotein IIb/IIIa integrin blockade. Circulation, 98, 2629-2635.
    • (1998) Circulation , vol.98 , pp. 2629-2635
    • Madan, M.1    Berkowitz, S.D.2    Tcheng, J.E.3
  • 24
    • 20244385431 scopus 로고    scopus 로고
    • Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention
    • 11419888 10.1016/S0735-1097(01)01290-6 1:CAS:528:DC%2BD3MXltFamu7w%3D
    • Anderson, K. M., Califf, R. M., Stone, G. W., Nemann, F.-J., Montalescot, G., Miller, D. P., et al. (2001). Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention. Journal of the American College of Cardiology, 37, 2059-2065.
    • (2001) Journal of the American College of Cardiology , vol.37 , pp. 2059-2065
    • Anderson, K.M.1    Califf, R.M.2    Stone, G.W.3    Nemann, F.-J.4    Montalescot, G.5    Miller, D.P.6
  • 25
    • 33845606632 scopus 로고    scopus 로고
    • Activation of platelet function through G protein coupled receptors
    • 17158345 10.1161/01.RES.0000251742.71301.16 1:CAS:528:DC%2BD28Xht1Ohu77F
    • Offermanns, S. (2006). Activation of platelet function through G protein coupled receptors. Circulation Research, 99, 1293-1304.
    • (2006) Circulation Research , vol.99 , pp. 1293-1304
    • Offermanns, S.1
  • 26
    • 33745742679 scopus 로고    scopus 로고
    • International Union of Pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy
    • 16968944 10.1124/pr.58.3.3 1:CAS:528:DC%2BD28XhtVOhtLbF
    • Abbracchio, M. P., Burnstock, G., Boeynaems, J. M., Barnard, E. A., Boyer, J. L., Kennedy, C., et al. (2006). International Union of Pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy. Pharmacological Reviews, 58, 281-341.
    • (2006) Pharmacological Reviews , vol.58 , pp. 281-341
    • Abbracchio, M.P.1    Burnstock, G.2    Boeynaems, J.M.3    Barnard, E.A.4    Boyer, J.L.5    Kennedy, C.6
  • 27
    • 77955271870 scopus 로고    scopus 로고
    • Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba- 2′-deoxyadenosine-3′,5′-bisphosphate ([(125)I]MRS2500)
    • 20594939 10.1016/j.phrs.2010.05.007 1:CAS:528:DC%2BC3cXpvVKnu7o%3D
    • Ohlmann, P., Castro, S., Brown, G. G., Jr., Gachet, C., Jacobson, K. A., & Harden, T. K. (2010). Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2′-deoxyadenosine-3′, 5′-bisphosphate ([(125)I]MRS2500). Pharmacological Research, 62(4), 344-351.
    • (2010) Pharmacological Research , vol.62 , Issue.4 , pp. 344-351
    • Ohlmann, P.1    Castro, S.2    Brown, Jr.G.G.3    Gachet, C.4    Jacobson, K.A.5    Harden, T.K.6
  • 28
    • 0031916728 scopus 로고    scopus 로고
    • 1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets
    • 9442040 10.1074/jbc.273.4.2030 1:CAS:528:DyaK1cXnsVCrsg%3D%3D
    • 1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. Journal of Biological Chemistry, 273(4), 2030-2034.
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.4 , pp. 2030-2034
    • Jin, J.1    Daniel, J.L.2    Kunapuli, S.P.3
  • 31
    • 4444257333 scopus 로고    scopus 로고
    • 12 receptors at the level of calcium signaling in human platelets
    • 15187029 10.1182/blood-2004-02-0534 1:CAS:528:DC%2BD2cXns1Oktb0%3D
    • 12 receptors at the level of calcium signaling in human platelets. Blood, 104(6), 1745-1752.
    • (2004) Blood , vol.104 , Issue.6 , pp. 1745-1752
    • Hardy, A.R.1    Jones, M.L.2    Mundell, S.J.3    Poole, A.W.4
  • 32
    • 0037195456 scopus 로고    scopus 로고
    • Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors
    • 12297509 10.1074/jbc.M208519200 1:CAS:528:DC%2BD3sXivV2q
    • Yang, J., Wu, J., Jiang, H., Mortensen, R., Austin, S., Manning, D. R., et al. (2002). Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors. Journal of Biological Chemistry, 277(48), 46035-46042.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.48 , pp. 46035-46042
    • Yang, J.1    Wu, J.2    Jiang, H.3    Mortensen, R.4    Austin, S.5    Manning, D.R.6
  • 33
    • 77950423041 scopus 로고    scopus 로고
    • Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
    • 20065293 10.1182/blood-2009-04-217224 1:CAS:528:DC%2BC3cXhtFensbbF
    • Martin, V., Guillermet-Guibert, J., Chicanne, G., Cabou, C., Jandrot-Perrus, M., Plantavid, M., et al. (2010). Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo. Blood, 115(10), 2008-2013.
    • (2010) Blood , vol.115 , Issue.10 , pp. 2008-2013
    • Martin, V.1    Guillermet-Guibert, J.2    Chicanne, G.3    Cabou, C.4    Jandrot-Perrus, M.5    Plantavid, M.6
  • 34
    • 0035464192 scopus 로고    scopus 로고
    • Resistance to thromboembolism in PI3Kgamma-deficient mice
    • 1:CAS:528:DC%2BD3MXntlGkur0%3D
    • Hirsch, E., Bosco, O., Tropel, P., Laffargue, M., Calvez, R., Altruda, F., et al. (2001). Resistance to thromboembolism in PI3Kgamma-deficient mice. The FASEB Journal, 15(11), 2019-2021.
    • (2001) The FASEB Journal , vol.15 , Issue.11 , pp. 2019-2021
    • Hirsch, E.1    Bosco, O.2    Tropel, P.3    Laffargue, M.4    Calvez, R.5    Altruda, F.6
  • 35
    • 0032493295 scopus 로고    scopus 로고
    • Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation
    • 10.1073/pnas.95.14.8070 1:CAS:528:DyaK1cXks1Sktr0%3D
    • Jin, J., & Kunapuli, S. P. (1998). Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. Proceedings National Academy Science USA, 95(14), 8070-8074.
    • (1998) Proceedings National Academy Science USA , vol.95 , Issue.14 , pp. 8070-8074
    • Jin, J.1    Kunapuli, S.P.2
  • 37
    • 0026052859 scopus 로고
    • Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists
    • 1892057 10.1016/0002-9149(91)90379-Y 1:STN:280:DyaK3MzmvVKquw%3D%3D
    • FitzGerald, G. A. (1991). Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists. The American Journal of Cardiology, 68, 11B-15B.
    • (1991) The American Journal of Cardiology , vol.68
    • Fitzgerald, G.A.1
  • 39
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: Contribution to physiology and disease
    • 15044683 10.1152/physrev.00028.2003 1:CAS:528:DC%2BD2cXjtlCktLY%3D
    • Ossovskaya, V. S., & Bunnett, N. W. (2004). Protease-activated receptors: Contribution to physiology and disease. Physiological Reviews, 84, 579-621.
    • (2004) Physiological Reviews , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 40
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • 1672265 10.1016/0092-8674(91)90261-V 1:CAS:528:DyaK3MXlsFehu7w%3D
    • Vu, T. K., Hung, D. T., Wheaton, VI, & Coughlin, S. R. (1991). Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell, 64, 1057-1068.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 41
    • 0035952643 scopus 로고    scopus 로고
    • Protease activated receptors: Theme and variations
    • 11313904 10.1038/sj.onc.1204194
    • O'Brien, P. J., Molino, M., Kahn, M., & Brass, L. F. (2001). Protease activated receptors: Theme and variations. Oncogene, 20, 1570-1581.
    • (2001) Oncogene , vol.20 , pp. 1570-1581
    • O'Brien, P.J.1    Molino, M.2    Kahn, M.3    Brass, L.F.4
  • 43
    • 13444249470 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response
    • 15689571 10.1210/er.2003-0025 1:CAS:528:DC%2BD2MXitFyktrc%3D
    • Steinhoff, M., Buddenkotte, J., Shpacovitch, V., Rattenholl, A., Moormann, C., Vergnolle, N., et al. (2005). Proteinase-activated receptors: Transducers of proteinase-mediated signaling in inflammation and immune response. Endocrine Reviews, 26, 1-43.
    • (2005) Endocrine Reviews , vol.26 , pp. 1-43
    • Steinhoff, M.1    Buddenkotte, J.2    Shpacovitch, V.3    Rattenholl, A.4    Moormann, C.5    Vergnolle, N.6
  • 44
    • 0034682810 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin
    • 10837487 10.1074/jbc.M004589200 1:CAS:528:DC%2BD3cXmtVeiu78%3D
    • Shapiro, M. J., Weiss, E. J., Faruqi, T. R., & Coughlin, S. R. (2000). Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin. Journal of Biological Chemistry, 275, 25216-25221.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 25216-25221
    • Shapiro, M.J.1    Weiss, E.J.2    Faruqi, T.R.3    Coughlin, S.R.4
  • 45
    • 0023762799 scopus 로고
    • Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction
    • 3403726 10.1172/JCI113656 1:CAS:528:DyaL1cXlsVGktr8%3D
    • Newman, P. J., Gorski, J., & White, G. C., 2nd. (1988). Enzymatic amplification of platelet-specific messenger RNA using the polymerase chain reaction. The Journal of Clinical Investigation, 82, 739-743.
    • (1988) The Journal of Clinical Investigation , vol.82 , pp. 739-743
    • Newman, P.J.1    Gorski, J.2    White, I.I.G.C.3
  • 46
    • 0037443545 scopus 로고    scopus 로고
    • Transcript profiling of human platelets using microarray and serial analysis of gene expression
    • 12433680 10.1182/blood-2002-09-2797 1:CAS:528:DC%2BD3sXit1egsbY%3D
    • Gnatenko, D. V., Dunn, J. J., & McCorkle, S. R. (2003). Transcript profiling of human platelets using microarray and serial analysis of gene expression. Blood, 101, 2285-2293.
    • (2003) Blood , vol.101 , pp. 2285-2293
    • Gnatenko, D.V.1    Dunn, J.J.2    McCorkle, S.R.3
  • 47
    • 0023120571 scopus 로고
    • Biosynthesis of major platelet proteins in human blood platelets
    • 3830180 10.1111/j.1432-1033.1987.tb11010.x 1:CAS:528:DyaL2sXhsFersro%3D
    • Kieffer, N., Guichard, J., & Farcet, J. P. (1987). Biosynthesis of major platelet proteins in human blood platelets. European Journal of Biochemistry, 164, 189-195.
    • (1987) European Journal of Biochemistry , vol.164 , pp. 189-195
    • Kieffer, N.1    Guichard, J.2    Farcet, J.P.3
  • 48
    • 4444303858 scopus 로고    scopus 로고
    • Change in protein phenotype without a nucleus: Translational control in platelets
    • 15354270 10.1055/s-2004-833484 1:CAS:528:DC%2BD2MXotFyrtA%3D%3D
    • Weyrich, A. S., Lindemann, S., & Tolley, N. D. (2004). Change in protein phenotype without a nucleus: Translational control in platelets. Seminars in Thrombosis and Hemostasis, 30, 491-498.
    • (2004) Seminars in Thrombosis and Hemostasis , vol.30 , pp. 491-498
    • Weyrich, A.S.1    Lindemann, S.2    Tolley, N.D.3
  • 49
    • 33744997382 scopus 로고    scopus 로고
    • Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events
    • 16682612 10.1161/CIRCULATIONAHA.105.607333 1:CAS:528:DC%2BD28XktlSjt74%3D
    • Healy, A. M., Pickard, M. D., & Pradhan, A. D. (2006). Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation, 113, 2278-2284.
    • (2006) Circulation , vol.113 , pp. 2278-2284
    • Healy, A.M.1    Pickard, M.D.2    Pradhan, A.D.3
  • 50
    • 23744515307 scopus 로고    scopus 로고
    • Escaping the nuclear confines: Signal-dependent pre-mRNA splicing in anucleate platelets
    • 16096058 10.1016/j.cell.2005.06.015 1:CAS:528:DC%2BD2MXovV2qsrY%3D
    • Denis, M. M., Tolley, N. D., & Bunting, M. (2005). Escaping the nuclear confines: Signal-dependent pre-mRNA splicing in anucleate platelets. Cell, 122, 379-391.
    • (2005) Cell , vol.122 , pp. 379-391
    • Denis, M.M.1    Tolley, N.D.2    Bunting, M.3
  • 51
    • 33750517555 scopus 로고    scopus 로고
    • Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets
    • 17060476 10.1084/jem.20061302 1:CAS:528:DC%2BD28XhtFGqtL7M
    • Schwertz, H., Tolley, N. D., & Foulks, J. M. (2006). Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. The Journal of Experimental Medicine, 203, 2433-2440.
    • (2006) The Journal of Experimental Medicine , vol.203 , pp. 2433-2440
    • Schwertz, H.1    Tolley, N.D.2    Foulks, J.M.3
  • 52
    • 49949116902 scopus 로고    scopus 로고
    • 18668037 10.1038/nature07242 1:CAS:528:DC%2BD1cXhtVKrsbjF
    • Baek, D., Villen, J., & Shin, C. (2008). Nature, 455, 64-71.
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1    Villen, J.2    Shin, C.3
  • 53
    • 77649253288 scopus 로고    scopus 로고
    • MicroRNAs add a new dimension to cardiovascular disease
    • Small, E.M., Frost, R.J., Olson, E.N. (2010). MicroRNAs add a new dimension to cardiovascular disease. Circulation, 121, 1022-1032.
    • (2010) Circulation , vol.121 , pp. 1022-1032
    • Small, E.M.1    Frost, R.J.2    Olson, E.N.3
  • 54
    • 69949124465 scopus 로고    scopus 로고
    • Existence of a microRNA pathway in anucleate platelets
    • 19668211 10.1038/nsmb.1651 1:CAS:528:DC%2BD1MXps1ahtbc%3D
    • Landry, P., Plante, I., & Ouellet, D. L. (2009). Existence of a microRNA pathway in anucleate platelets. Nature Structural and Molecular Biology, 16(9), 961-966.
    • (2009) Nature Structural and Molecular Biology , vol.16 , Issue.9 , pp. 961-966
    • Landry, P.1    Plante, I.2    Ouellet, D.L.3
  • 57
    • 65949110335 scopus 로고    scopus 로고
    • TP receptor antagonism: A new concept in atherothrombosis and stroke prevention
    • 19439937 10.1159/000209262 1:CAS:528:DC%2BD1MXmtFekt7k%3D Epub 2009 May 14
    • Chamorro, A. (2009). TP receptor antagonism: A new concept in atherothrombosis and stroke prevention. Cerebrovascular Diseases, 27(Suppl 3), 20-27. Epub 2009 May 14.
    • (2009) Cerebrovascular Diseases , vol.27 , Issue.SUPPL. 3 , pp. 20-27
    • Chamorro, A.1
  • 59
    • 34247398257 scopus 로고    scopus 로고
    • The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats
    • 17322098 10.1161/ATVBAHA.107.140590 1:CAS:528:DC%2BD2sXktFagtLc%3D
    • Li, H., Lockyer, S., Concepcion, A., Gong, X., Takizawa, H., Guertin, M., et al. (2007). The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats. Arteriosclerosis, Thrombosis, and Vascular Biology, 27, 1199-1205.
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 1199-1205
    • Li, H.1    Lockyer, S.2    Concepcion, A.3    Gong, X.4    Takizawa, H.5    Guertin, M.6
  • 60
    • 1442290149 scopus 로고    scopus 로고
    • Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo
    • 1:CAS:528:DC%2BD2cXht1GjtLg%3D
    • Massberg, S., Konrad, I., Bültmann, A., Schulz, C., Münch, G., Peluso, M., et al. (2004). Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. The FASEB Journal, 18, 397-399.
    • (2004) The FASEB Journal , vol.18 , pp. 397-399
    • Massberg, S.1    Konrad, I.2    Bültmann, A.3    Schulz, C.4    Münch, G.5    Peluso, M.6
  • 61
    • 85027958733 scopus 로고    scopus 로고
    • Novel antiplatelet drug revacept (dimeric glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans
    • 21502572 10.1161/CIRCULATIONAHA.110.980623 1:CAS:528:DC%2BC3MXlsVyntrk%3D
    • Ungerer, M., Rosport, K., Bültmann, A., Piechatzek, R., Uhland, K., Schlieper, P., et al. (2011). Novel antiplatelet drug revacept (dimeric glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans. Circulation, 123, 1891-1899.
    • (2011) Circulation , vol.123 , pp. 1891-1899
    • Ungerer, M.1    Rosport, K.2    Bültmann, A.3    Piechatzek, R.4    Uhland, K.5    Schlieper, P.6
  • 65
    • 83655177669 scopus 로고    scopus 로고
    • Thrombin-receptor antagonist vorapaxar in acute coronary syndromes
    • 22077816 10.1056/NEJMoa1109719 1:CAS:528:DC%2BC38XhtVKit7c%3D Epub 2011 Nov 13
    • Tricoci, P., Huang, Z., Held, C., Moliterno, D. J., Armstrong, P. W., Van de Werf, F., et al. (2012). Thrombin-receptor antagonist vorapaxar in acute coronary syndromes. The New England Journal of Medicine, 366(1), 20-33. Epub 2011 Nov 13.
    • (2012) The New England Journal of Medicine , vol.366 , Issue.1 , pp. 20-33
    • Tricoci, P.1    Huang, Z.2    Held, C.3    Moliterno, D.J.4    Armstrong, P.W.5    Van De Werf, F.6
  • 67
    • 68949156886 scopus 로고    scopus 로고
    • Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2 degrees P)-TIMI 50 trial
    • Morrow, D. A., Scirica, B. M., Fox, K. A., Berman, G., Strony, J., Veltri, E., et al. (2009). Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the Thrombin-Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2 degrees P)-TIMI 50 trial. American Heart Journal, 158(335-341), e333.
    • (2009) American Heart Journal , vol.158 , Issue.335-341 , pp. 333
    • Morrow, D.A.1    Scirica, B.M.2    Fox, K.A.3    Berman, G.4    Strony, J.5    Veltri, E.6
  • 68
    • 2142695733 scopus 로고    scopus 로고
    • Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic
    • 10.1096/fj.03-0645rev 1:CAS:528:DC%2BD2cXjvVOntrs%3D
    • Warner, T. D., & Mitchell, J. A. (2004). Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic. The FASEB Journal, 18, 790-804.
    • (2004) The FASEB Journal , vol.18 , pp. 790-804
    • Warner, T.D.1    Mitchell, J.A.2
  • 69
    • 0034971264 scopus 로고    scopus 로고
    • Why there are two cyclooxygenase isozymes
    • 11413152 10.1172/JCI13271 1:CAS:528:DC%2BD3MXksFeqsL4%3D
    • Smith, W. L., & Langenbach, R. (2001). Why there are two cyclooxygenase isozymes. The Journal of Clinical Investigation, 107(12), 1491-1495.
    • (2001) The Journal of Clinical Investigation , vol.107 , Issue.12 , pp. 1491-1495
    • Smith, W.L.1    Langenbach, R.2
  • 73
    • 0029040041 scopus 로고
    • Biochemistry of prostaglandin endoperoxide H synthase and their differential susceptibility to nonsteroidal anti-inflammatory drugs
    • 7631045 1:CAS:528:DyaK2MXmslGrtLc%3D
    • Smith, W. L., & DeWitt, D. L. (1995). Biochemistry of prostaglandin endoperoxide H synthase and their differential susceptibility to nonsteroidal anti-inflammatory drugs. Seminars in Nephrology, 15, 179-194.
    • (1995) Seminars in Nephrology , vol.15 , pp. 179-194
    • Smith, W.L.1    Dewitt, D.L.2
  • 74
    • 0028810964 scopus 로고
    • Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2
    • 7592599 10.1074/jbc.270.18.10503 1:CAS:528:DyaK2MXovVSgtr0%3D
    • Kulmacz, R. J., & Wang, L. H. (1995). Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2. Journal of Biological Chemistry, 270, 24019.
    • (1995) Journal of Biological Chemistry , vol.270 , pp. 24019
    • Kulmacz, R.J.1    Wang, L.H.2
  • 76
    • 84867391556 scopus 로고    scopus 로고
    • Crosstalk between platelets and the immune system: Old systems with new discoveries
    • 23008717 10.1155/2012/384685 Epub 2012 Sep 12
    • Li, C., Li, J., Li, Y., Lang, S., Yougbare, I., Zhu, G., et al. (2012). Crosstalk between platelets and the immune system: Old systems with new discoveries. Advances in Hematology, 2012, 384685. Epub 2012 Sep 12.
    • (2012) Advances in Hematology , vol.2012 , pp. 384685
    • Li, C.1    Li, J.2    Li, Y.3    Lang, S.4    Yougbare, I.5    Zhu, G.6
  • 77
    • 30444436765 scopus 로고    scopus 로고
    • Platelet Toll-like receptor expression modulates lipopolysaccharide- induced thrombocytopenia and tumor necrosis factor-α production in vivo
    • 16179373 10.1182/blood-2005-06-2202 1:CAS:528:DC%2BD28Xms1ektA%3D%3D
    • Aslam, R., Speck, E. R., Kim, M., et al. (2006). Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo. Blood, 107(2), 637-641.
    • (2006) Blood , vol.107 , Issue.2 , pp. 637-641
    • Aslam, R.1    Speck, E.R.2    Kim, M.3
  • 78
    • 77950349016 scopus 로고    scopus 로고
    • Th17 and regulatory T cells in mediating and restraining inflammation
    • 20303875 10.1016/j.cell.2010.02.021 1:CAS:528:DC%2BC3cXlsVSgu70%3D
    • Littman, D. R., & Rudensky, A. Y. (2010). Th17 and regulatory T cells in mediating and restraining inflammation. Cell, 140(6), 845-858.
    • (2010) Cell , vol.140 , Issue.6 , pp. 845-858
    • Littman, D.R.1    Rudensky, A.Y.2
  • 79
    • 0031012138 scopus 로고    scopus 로고
    • P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues
    • 8985251 10.1038/385081a0 1:CAS:528:DyaK2sXivVSnug%3D%3D
    • Austrup, F., Vestweber, D., Borges, E., et al. (1997). P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature, 385(6611), 81-83.
    • (1997) Nature , vol.385 , Issue.6611 , pp. 81-83
    • Austrup, F.1    Vestweber, D.2    Borges, E.3
  • 80
    • 0038445960 scopus 로고    scopus 로고
    • Platelet-mediated modulation of adaptive immunity: A communication link between innate and adaptive immune compartments
    • 12871635 10.1016/S1074-7613(03)00177-8 1:CAS:528:DC%2BD3sXlvVOrsrw%3D
    • Elzey, B. D., Tian, J., Jensen, R. J., et al. (2003). Platelet-mediated modulation of adaptive immunity: A communication link between innate and adaptive immune compartments. Immunity, 19(1), 9-19.
    • (2003) Immunity , vol.19 , Issue.1 , pp. 9-19
    • Elzey, B.D.1    Tian, J.2    Jensen, R.J.3
  • 81
    • 70350244537 scopus 로고    scopus 로고
    • Platelet-derived transforming growth factor-β down-regulates NKG2D thereby inhibiting natural killer cell antitumor reactivity
    • 19738039 10.1158/0008-5472.CAN-09-2123 1:CAS:528:DC%2BD1MXht1Skt7nP
    • Kopp, H. G., Placke, T., & Salih, H. R. (2009). Platelet-derived transforming growth factor-β down-regulates NKG2D thereby inhibiting natural killer cell antitumor reactivity. Cancer Research, 69(19), 7775-7783.
    • (2009) Cancer Research , vol.69 , Issue.19 , pp. 7775-7783
    • Kopp, H.G.1    Placke, T.2    Salih, H.R.3
  • 83
    • 12344320716 scopus 로고    scopus 로고
    • Thrombospondin-1 is a major activator of TGF-β1 in vivo
    • 9657149 10.1016/S0092-8674(00)81460-9 1:CAS:528:DyaK1cXksVSqs7c%3D
    • Crawford, S. E., Stellmach, V., Murphy-Ullrich, J. E., et al. (1998). Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell, 93(7), 1159-1170.
    • (1998) Cell , vol.93 , Issue.7 , pp. 1159-1170
    • Crawford, S.E.1    Stellmach, V.2    Murphy-Ullrich, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.