Prevalence and incidence of anemia in the German Heinz Nixdorf Recall Study

Annals of Hematology

Volumn 92, Issue 6, 2013, Pages 731-737

  Eisele, Lewin ^a   Dürig, Jan ^a   Broecker Preuss, Martina ^a   Dührsen, Ulrich ^a   Bokhof, Beate ^a   Erbel, Raimund ^a   Moebus, Susanne ^a   Jöckel, Karl Heinz ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Anemia; Biomarker; Incidence; Population based; Prevalence

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; IMMUNOGLOBULIN LIGHT CHAIN;

ADULT; AGE DISTRIBUTION; AGED; ANEMIA; ANEMIA OF CHRONIC DISEASE; ARTICLE; DEATH CERTIFICATE; FEMALE; FOLIC ACID DEFICIENCY; FOLLOW UP; GERMANY; HUMAN; INCIDENCE; IRON DEFICIENCY ANEMIA; MAJOR CLINICAL STUDY; MALE; PERNICIOUS ANEMIA; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; RENAL ANEMIA; SEX RATIO; UNEXPLAINED ANEMIA;

AGE DISTRIBUTION; AGED; ANEMIA; ANEMIA, IRON-DEFICIENCY; ANEMIA, MACROCYTIC; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CHRONIC DISEASE; FEMALE; FOLIC ACID DEFICIENCY; FOLLOW-UP STUDIES; GERMANY; HEMOGLOBINS; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; INCIDENCE; MALE; MIDDLE AGED; PREVALENCE; RISK; SEX DISTRIBUTION; VITAMIN B 12 DEFICIENCY;

EID: 84877734919     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1697-1     Document Type: Article

References (26)

1. Merchant AA, Roy CN (2012) Not so benign haematology: anaemia of the elderly. Br J Haematol 156(2):173-185
2. Gaskell H, Derry S, Andrew Moore R, McQuay HJ (2008) Prevalence of anaemia in older persons: systematic review. BMC Geriatr 8:1. doi: 10.1186/1471-2318-8-1
3. Ferrucci L, Maggio M, Bandinelli S, Basaria S, Lauretani F, Ble A, Valenti G, Ershler WB, Guralnik JM, Longo DL (2006) Low testosterone levels and the risk of anemia in older men and women. Arch Intern Med 166(13):1380-1388
4. Ershler WB, Sheng S, McKelvey J, Artz AS, Denduluri N, Tecson J, Taub DD, Brant LJ, Ferrucci L, Longo DL (2005) Serum erythropoietin and aging: a longitudinal analysis. J Am Geriatr Soc 53(8):1360-1365
5. Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC (2004) Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood 104(8):2263-2268
6. Bradwell AR, Carr-Smith HD, Mead GP, Tang LX, Showell PJ, Drayson MT, Drew R (2001) Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine. Clin Chem 47(4):673-680
7. Hutchison CA, Basnayake K, Cockwell P (2009) Serum free light chain assessment in monoclonal gammopathy and kidney disease. Nat Rev Nephrol 5(11):621-628
8. Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, Palumbo A, Jagannath S, Blade J, Lonial S, Dimopoulos M, Comenzo R, Einsele H, Barlogie B, Anderson K, Gertz M, Harousseau JL, Attal M, Tosi P, Sonneveld P, Boccadoro M, Morgan G, Richardson P, Sezer O, Mateos MV, Cavo M, Joshua D, Turesson I, Chen W, Shimizu K, Powles R, Rajkumar SV, Durie BG (2009) International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 23(2):215-224
9. Hutchison CA, Landgren O (2011) Polyclonal immunoglobulin free light chains as a potential biomarker of immune stimulation and inflammation. Clin Chem 57(10):1387-1389
10. Schmermund A, Möhlenkamp S, Stang A, Grönemeyer D, Seibel R, Hirche H, Mann K, Siffert W, Lauterbach K, Siegrist J, Jöckel KH, Erbel R (2002) Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf RECALL Study. Risk Factors, Evaluation of Coronary Calcium and Lifestyle. Am Heart J 144(2):212-218
11. Eisele L, Dürig J, Hüttmann A, Dührsen U, Assert R, Bokhof B, Erbel R, Mann K, Jöckel KH, Moebus S (2012) Prevalence and progression of monoclonal gammopathy of undetermined significance and light-chain MGUS in Germany. Ann Hematol 91(2):243-248
12. Stang A, Moebus S, Dragano N, Beck EM, Möhlenkamp S, Schmermund A, Siegrist J, Erbel R, Jöckel KH (2005) Baseline recruitment and analyses of nonresponse of the Heinz Nixdorf Recall Study: identifiability of phone numbers as the major determinant of response. Eur J Epidemiol 20(6):489-496
13. Katzmann JA, Clark RJ, Abraham RS, Bryant S, Lymp JF, Bradwell AR, Kyle RA (2002) Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 48(9):1437-1444
14. Dürig J, Eisele L, Hüttmann A, Dührsen U, Führer A, Kieruzel S, Bokhof B, Erbel R, Mann K, Jöckel K-H, Moebus S (2010) Polyclonal free light chain elevation and mortality in the German Heinz Nixdorf Recall study. Hematol Rep 2:13
15. Endres HG, Wedding U, Pittrow D, Thiem U, Trampisch HJ, Diehm C (2009) Prevalence of anemia in elderly patients in primary care: impact on 5-year mortality risk and differences between men and women. Curr Med Res and Opin 25(5):1143-1158
16. Tettamanti M, Lucca U, Gandini F, Recchia A, Mosconi P, Apolone G, Nobili A, Tallone MV, Detoma P, Giacomin A, Clerico M, Tempia P, Savoia L, Fasolo G, Ponchio L, Della Porta MG, Riva E (2010) Prevalence, incidence and types of mild anemia in the elderly: the «Health and Anemia» population-based study. Haematologica 95(11):1849-1856
17. Coad J, Conlon C (2011) Iron deficiency in women: assessment, causes and consequences. Curr Opin Clin Nutr Metab Care 14(6):625-634
18. Ferrucci L, Guralnik JM, Woodman RC, Bandinelli S, Lauretani F, Corsi AM, Chaves PH, Ershler WB, Longo DL (2005) Proinflammatory state and circulating erythropoietin in persons with and without anemia. Am J Med 118(11):1288
19. Grundy SM (2001) Coronary calcium as a risk factor: role in global risk assessment. J Am Coll Cardiol 37(6):1512-1515
20. Hamirani YS, Pandey S, Rivera JJ, Ndumele C, Budoff MJ, Blumenthal RS, Nasir K (2008) Markers of inflammation and coronary artery calcification: a systematic review. Atherosclerosis 201(1):1-7
21. Hutchison CA, Harding S, Hewins P, Mead GP, Townsend J, Bradwell AR, Cockwell P (2008) Quantitative assessment of serum and urinary polyclonal free light chains in patients with chronic kidney disease. Clin J Am Soc Nephrology: CJASN 3(6):1684-1690
22. Pardanani A, Lasho TL, Finke CM, Rajkumar SV, Singh PP, Ketterling RP, Hanson CA, Katzmann JA, Tefferi A (2012) Polyclonal immunoglobulin free light chain levels predict survival in myeloid neoplasms. J Clin Oncol 30(10):1087-1094
23. Weiss G, Goodnough LT (2005) Anemia of chronic disease. N Engl J Med 352(10):1011-1023
24. Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL (2010) Proinflammatory state, hepcidin, and anemia in older persons. Blood 115(18):3810-3816
25. Waalen J, von Lohneysen K, Lee P, Xu X, Friedman JS (2011) Erythropoietin, GDF15, IL6, hepcidin and testosterone levels in a large cohort of elderly individuals with anaemia of known and unknown cause. Eur J Haematol 87(2):107-116
26. Artz AS, Thirman MJ (2011) Unexplained anemia predominates despite an intensive evaluation in a racially diverse cohort of older adults from a referral anemia clinic. J Gerontol A Biol Sci Med Sci 66(8):925-932