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Volumn 9, Issue 6, 2013, Pages 1489-1497

Gossypol induces apoptosis in ovarian cancer cells through oxidative stress

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CARRIER PROTEIN; CHAPERONIN 60; DISULFIDE; FLAVINE ADENINE NUCLEOTIDE; GLUTATHIONE; GOSSYPOL; HSPD1 PROTEIN, HUMAN; MALE CONTRACEPTIVE AGENT; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; PROTEOME; THIOL DERIVATIVE; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS; THYROID HORMONE BINDING PROTEINS;

EID: 84877730312     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/c3mb25461e     Document Type: Article
Times cited : (43)

References (51)
  • 2
    • 66849114911 scopus 로고    scopus 로고
    • Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: A study of the Gynecologic Oncology Group
    • D. S. Miller J. A. Blessing C. N. Krasner R. S. Mannel P. Hanjani M. L. Pearl et al., Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group J. Clin. Oncol. 2009 27 2686 2691
    • (2009) J. Clin. Oncol. , vol.27 , pp. 2686-2691
    • Miller, D.S.1    Blessing, J.A.2    Krasner, C.N.3    Mannel, R.S.4    Hanjani, P.5    Pearl, M.L.6
  • 4
    • 77950965840 scopus 로고    scopus 로고
    • Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
    • A. A. Ahmed D. Etemadmoghadam J. Temple A. G. Lynch M. Riad R. Sharma et al., Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary J. Pathol. 2010 221 49 56
    • (2010) J. Pathol. , vol.221 , pp. 49-56
    • Ahmed, A.A.1    Etemadmoghadam, D.2    Temple, J.3    Lynch, A.G.4    Riad, M.5    Sharma, R.6
  • 8
    • 0030614915 scopus 로고    scopus 로고
    • Structure of Bcl-xL-Bak peptide complex: Recognition between regulators of apoptosis
    • M. Sattler H. Liang D. Nettesheim R. P. Meadows J. E. Harlan M. Eberstadt et al., Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis Science 1997 275 983 986
    • (1997) Science , vol.275 , pp. 983-986
    • Sattler, M.1    Liang, H.2    Nettesheim, D.3    Meadows, R.P.4    Harlan, J.E.5    Eberstadt, M.6
  • 9
    • 17744396094 scopus 로고    scopus 로고
    • Rationale for Bcl-XL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies
    • A. M. Petros D. G. Nettesheim Y. Wang E. T. Olejniczak R. P. Meadows J. Mack et al., Rationale for Bcl-XL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies Protein Sci. 2000 9 2528 2534
    • (2000) Protein Sci. , vol.9 , pp. 2528-2534
    • Petros, A.M.1    Nettesheim, D.G.2    Wang, Y.3    Olejniczak, E.T.4    Meadows, R.P.5    MacK, J.6
  • 10
    • 0034691130 scopus 로고    scopus 로고
    • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
    • J. L. Wang D. Liu Z. J. Zhang S. Shan X. Han S. M. Srinivasula et al., Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells Proc. Natl. Acad. Sci. U. S. A. 2000 97 7124 7129
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 7124-7129
    • Wang, J.L.1    Liu, D.2    Zhang, Z.J.3    Shan, S.4    Han, X.5    Srinivasula, S.M.6
  • 11
    • 0035150803 scopus 로고    scopus 로고
    • Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
    • A. Degterev A. Lugovskoy M. Cardone B. Mulley G. Wagner T. Mitchison et al., Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL Nat. Cell Biol. 2001 3 173 182
    • (2001) Nat. Cell Biol. , vol.3 , pp. 173-182
    • Degterev, A.1    Lugovskoy, A.2    Cardone, M.3    Mulley, B.4    Wagner, G.5    Mitchison, T.6
  • 13
    • 33750112776 scopus 로고    scopus 로고
    • Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins
    • G. Wang Z. Nikolovska-Coleska C. Y. Yang R. Wang G. Tang J. Guo et al., Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins J. Med. Chem. 2006 49 6139 6142
    • (2006) J. Med. Chem. , vol.49 , pp. 6139-6142
    • Wang, G.1    Nikolovska-Coleska, Z.2    Yang, C.Y.3    Wang, R.4    Tang, G.5    Guo, J.6
  • 14
    • 13944262237 scopus 로고    scopus 로고
    • (-)-Gossypol acts directly on the mitochondria to overcome Bcl-2-and Bcl-XL-mediated apoptosis resistance
    • C. L. Oliver M. B. Miranda S. Shangary S. Land S. Wang D. E. Johnson (-)-Gossypol acts directly on the mitochondria to overcome Bcl-2-and Bcl-XL-mediated apoptosis resistance Mol. Cancer Ther. 2005 4 23 31
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 23-31
    • Oliver, C.L.1    Miranda, M.B.2    Shangary, S.3    Land, S.4    Wang, S.5    Johnson, D.E.6
  • 16
    • 78650170269 scopus 로고    scopus 로고
    • A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum
    • J. Lian X. Wu F. He D. Karnak W. Tang Y. Meng et al., A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum Cell Death Differ. 2010 18 60 71
    • (2010) Cell Death Differ. , vol.18 , pp. 60-71
    • Lian, J.1    Wu, X.2    He, F.3    Karnak, D.4    Tang, W.5    Meng, Y.6
  • 17
    • 51049106854 scopus 로고    scopus 로고
    • Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa
    • Y. Meng W. Tang Y. Dai X. Wu M. Liu Q. Ji et al., Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa Mol. Cancer Ther. 2008 7 2192 2202
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 2192-2202
    • Meng, Y.1    Tang, W.2    Dai, Y.3    Wu, X.4    Liu, M.5    Ji, Q.6
  • 20
    • 84863661689 scopus 로고    scopus 로고
    • Therapeutic targets in cancer cell metabolism and autophagy
    • H. Cheong C. Lu T. Lindsten C. B. Thompson Therapeutic targets in cancer cell metabolism and autophagy Nat. Biotechnol. 2012 30 671 678
    • (2012) Nat. Biotechnol. , vol.30 , pp. 671-678
    • Cheong, H.1    Lu, C.2    Lindsten, T.3    Thompson, C.B.4
  • 22
    • 67649559317 scopus 로고    scopus 로고
    • Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling
    • J. Jiang W. Ye Y. C. Lin Gossypol inhibits the growth of MAT-LyLu prostate cancer cells by modulation of TGFbeta/Akt signaling Int. J. Mol. Med. 2009 24 69 75
    • (2009) Int. J. Mol. Med. , vol.24 , pp. 69-75
    • Jiang, J.1    Ye, W.2    Lin, Y.C.3
  • 23
    • 76649113100 scopus 로고    scopus 로고
    • Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells and Prostate Tumor-Initiating Cells
    • S. R. Volate B. T. Kawasaki E. M. Hurt J. A. Milner Y. S. Kim J. White et al., Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells and Prostate Tumor-Initiating Cells Mol. Cancer Ther. 2010 9 461 470
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 461-470
    • Volate, S.R.1    Kawasaki, B.T.2    Hurt, E.M.3    Milner, J.A.4    Kim, Y.S.5    White, J.6
  • 24
    • 70450285202 scopus 로고    scopus 로고
    • AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis
    • S. F. Zerp R. Stoter G. Kuipers D. Yang M. E. Lippman W. J. Van Blitterswijk et al., AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis Radiat. Oncol. 2009 4 1 10
    • (2009) Radiat. Oncol. , vol.4 , pp. 1-10
    • Zerp, S.F.1    Stoter, R.2    Kuipers, G.3    Yang, D.4    Lippman, M.E.5    Van Blitterswijk, W.J.6
  • 25
    • 70350113625 scopus 로고    scopus 로고
    • ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway
    • Z. Y. Hu J. Sun X. F. Zhu D. Yang Y. X. Zeng ApoG2 induces cell cycle arrest of nasopharyngeal carcinoma cells by suppressing the c-Myc signaling pathway J. Transl. Med. 2009 7 74
    • (2009) J. Transl. Med. , vol.7 , pp. 74
    • Hu, Z.Y.1    Sun, J.2    Zhu, X.F.3    Yang, D.4    Zeng, Y.X.5
  • 26
    • 42749083872 scopus 로고    scopus 로고
    • Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells
    • D. O. Moon M. O. Kim J. D. Lee G. Y. Kim Gossypol suppresses NF-kappaB activity and NF-kappaB-related gene expression in human leukemia U937 cells Cancer Lett. 2008 264 192 200
    • (2008) Cancer Lett. , vol.264 , pp. 192-200
    • Moon, D.O.1    Kim, M.O.2    Lee, J.D.3    Kim, G.Y.4
  • 27
    • 79956046608 scopus 로고    scopus 로고
    • (-)-Gossypol Suppresses the Growth of Human Prostate Cancer Xenografts via Modulating VEGF Signaling-Mediated Angiogenesis
    • X. Pang Y. Wu B. Lu J. Chen J. Wang Z. Yi et al., (-)-Gossypol Suppresses the Growth of Human Prostate Cancer Xenografts via Modulating VEGF Signaling-Mediated Angiogenesis Mol. Cancer Ther. 2011 10 795 805
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 795-805
    • Pang, X.1    Wu, Y.2    Lu, B.3    Chen, J.4    Wang, J.5    Yi, Z.6
  • 28
    • 75149145509 scopus 로고    scopus 로고
    • The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: A preliminary molecular framework for gossypol enantiomers
    • U. Varol B. Karaca D. Tunali M. Degirmenci Y. Cirak D. Purcu et al., The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers Exp. Oncol. 2009 31 220 225
    • (2009) Exp. Oncol. , vol.31 , pp. 220-225
    • Varol, U.1    Karaca, B.2    Tunali, D.3    Degirmenci, M.4    Cirak, Y.5    Purcu, D.6
  • 29
    • 34548680503 scopus 로고    scopus 로고
    • Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells
    • C. H. Ko S. C. Shen L. Y. Yang C. W. Lin Y. C. Chen Gossypol reduction of tumor growth through ROS-dependent mitochondria pathway in human colorectal carcinoma cells Int. J. Cancer 2007 121 1670 1679
    • (2007) Int. J. Cancer , vol.121 , pp. 1670-1679
    • Ko, C.H.1    Shen, S.C.2    Yang, L.Y.3    Lin, C.W.4    Chen, Y.C.5
  • 30
    • 78149256773 scopus 로고    scopus 로고
    • Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to trail
    • B. Sung J. Ravindran S. Prasad M. K. Pandey B. B. Aggarwal Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to trail J. Biol. Chem. 2010 285 35418 35427
    • (2010) J. Biol. Chem. , vol.285 , pp. 35418-35427
    • Sung, B.1    Ravindran, J.2    Prasad, S.3    Pandey, M.K.4    Aggarwal, B.B.5
  • 32
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • D. Trachootham J. Alexandre P. Huang Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discovery 2009 8 579 591
    • (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 33
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • H. Pelicano D. Carney P. Huang ROS stress in cancer cells and therapeutic implications Drug Resist. Updates 2004 7 97 110
    • (2004) Drug Resist. Updates , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 34
    • 64549108112 scopus 로고    scopus 로고
    • Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies
    • J. Chandra Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies Antioxid. Redox Signaling 2009 11 1123 1137
    • (2009) Antioxid. Redox Signaling , vol.11 , pp. 1123-1137
    • Chandra, J.1
  • 35
    • 79851510345 scopus 로고    scopus 로고
    • Chemical 'omics' approaches for understanding protein cysteine oxidation in biology
    • S. E. Leonard K. S. Carroll Chemical 'omics' approaches for understanding protein cysteine oxidation in biology Curr. Opin. Chem. Biol. 2011 15 88 102
    • (2011) Curr. Opin. Chem. Biol. , vol.15 , pp. 88-102
    • Leonard, S.E.1    Carroll, K.S.2
  • 38
    • 84857607634 scopus 로고    scopus 로고
    • Proteomic Profile of Reversible Protein Oxidation Using PROP, Purification of Reversibly Oxidized Proteins
    • K. G. Victor J. M. Rady J. V. Cross D. J. Templeton Proteomic Profile of Reversible Protein Oxidation Using PROP, Purification of Reversibly Oxidized Proteins PLoS One 2012 7 e32527
    • (2012) PLoS One , vol.7 , pp. 32527
    • Victor, K.G.1    Rady, J.M.2    Cross, J.V.3    Templeton, D.J.4
  • 39
    • 79957441981 scopus 로고    scopus 로고
    • The disulfide proteome and other reactive cysteine proteomes: Analysis and functional significance
    • M. Lindahl A. Mata-Cabana T. Kieselbach The disulfide proteome and other reactive cysteine proteomes: analysis and functional significance Antioxid. Redox Signaling 2011 14 2581 2642
    • (2011) Antioxid. Redox Signaling , vol.14 , pp. 2581-2642
    • Lindahl, M.1    Mata-Cabana, A.2    Kieselbach, T.3
  • 40
    • 0027232299 scopus 로고
    • Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins
    • H. Morimoto S. Yonehara B. Bonavida Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins Cancer Res. 1993 53 2591 2596
    • (1993) Cancer Res. , vol.53 , pp. 2591-2596
    • Morimoto, H.1    Yonehara, S.2    Bonavida, B.3
  • 41
    • 0026001496 scopus 로고
    • Synergistic effect of tumor necrosis factor-alpha-and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines
    • H. Morimoto J. T. Safrit B. Bonavida Synergistic effect of tumor necrosis factor-alpha-and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines J. Immunol. 1991 147 2609 2616
    • (1991) J. Immunol. , vol.147 , pp. 2609-2616
    • Morimoto, H.1    Safrit, J.T.2    Bonavida, B.3
  • 43
    • 16644389632 scopus 로고    scopus 로고
    • Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis
    • Y. Higuchi Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis J. Cell. Mol. Med. 2004 8 455 464
    • (2004) J. Cell. Mol. Med. , vol.8 , pp. 455-464
    • Higuchi, Y.1
  • 44
    • 79953715374 scopus 로고    scopus 로고
    • Glutathione in cancer cell death
    • A. L. Ortega S. Mena J. M. Estrela Glutathione in cancer cell death Cancers 2011 3 1285 1310
    • (2011) Cancers , vol.3 , pp. 1285-1310
    • Ortega, A.L.1    Mena, S.2    Estrela, J.M.3
  • 46
    • 18844397363 scopus 로고    scopus 로고
    • Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity
    • Y. Nagumo H. Kakeya M. Shoji Y. Hayashi N. Dohmae H. Osada Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity Biochem. J. 2005 387 835 840
    • (2005) Biochem. J. , vol.387 , pp. 835-840
    • Nagumo, Y.1    Kakeya, H.2    Shoji, M.3    Hayashi, Y.4    Dohmae, N.5    Osada, H.6
  • 47
    • 82755166890 scopus 로고    scopus 로고
    • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
    • D. Anastasiou G. Poulogiannis J. M. Asara M. B. Boxer J. Jiang M. Shen et al., Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses Sci. Signaling 2011 334 1278 1283
    • (2011) Sci. Signaling , vol.334 , pp. 1278-1283
    • Anastasiou, D.1    Poulogiannis, G.2    Asara, J.M.3    Boxer, M.B.4    Jiang, J.5    Shen, M.6
  • 48
    • 82755165163 scopus 로고    scopus 로고
    • Warburg effect and redox balance
    • R. B. Hamanaka N. S. Chandel Warburg effect and redox balance Sci. Signaling 2011 334 1219 1220
    • (2011) Sci. Signaling , vol.334 , pp. 1219-1220
    • Hamanaka, R.B.1    Chandel, N.S.2
  • 50
    • 34347329257 scopus 로고    scopus 로고
    • Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress
    • C. S. Velu S. K. Niture C. E. Doneanu N. Pattabiraman K. S. Srivenugopal Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress Biochemistry 2007 46 7765 7780
    • (2007) Biochemistry , vol.46 , pp. 7765-7780
    • Velu, C.S.1    Niture, S.K.2    Doneanu, C.E.3    Pattabiraman, N.4    Srivenugopal, K.S.5
  • 51
    • 84876732283 scopus 로고    scopus 로고
    • Redox Regulation of Tumour Suppressor Protein p53: Identification of the Sites of Hydrogen Peroxide Oxidation and Glutathionylation
    • J. Scotcher D. Clarke L. Mackay T. Hupp P. J. Sadler P. Langridge-Smith Redox Regulation of Tumour Suppressor Protein p53: Identification of the Sites of Hydrogen Peroxide Oxidation and Glutathionylation Chem. Sci. 2013 4 1257 1269
    • (2013) Chem. Sci. , vol.4 , pp. 1257-1269
    • Scotcher, J.1    Clarke, D.2    MacKay, L.3    Hupp, T.4    Sadler, P.J.5    Langridge-Smith, P.6


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