Coexisting primary hyperparathyroidism and sarcoidosis cause increased angiotensin-converting enzyme and decreased parathyroid hormone and phosphate levels

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 5, 2013, Pages 1939-1945

  Lim, Vivien ^a   Clarke, Bart L ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCITRIOL; CALCIUM; DIPEPTIDYL CARBOXYPEPTIDASE; PARATHYROID HORMONE; PHOSPHATE; PREDNISONE; STEROID;

ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM URINE LEVEL; CLINICAL ARTICLE; CLINICAL FEATURE; COMORBIDITY; ENZYME BLOOD LEVEL; FEMALE; HUMAN; HYPERCALCEMIA; LABORATORY TEST; MALE; OBSERVATIONAL STUDY; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SARCOIDOSIS; VITAMIN BLOOD LEVEL;

AGED; CALCIUM; COHORT STUDIES; DOWN-REGULATION; FEMALE; HUMANS; HYPERPARATHYROIDISM, PRIMARY; HYPOPHOSPHATEMIA; MALE; MIDDLE AGED; PARATHYROID HORMONE; PEPTIDYL-DIPEPTIDASE A; PHOSPHORUS; RETROSPECTIVE STUDIES; SARCOIDOSIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS; UP-REGULATION; VITAMIN D;

EID: 84877711256     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-4197     Document Type: Article

References (31)

1. Rybicki BA, Major M, Popovich J Jr, Maliarik MJ, Iannuzzi MC. Racial differences in sarcoidosis incidence: a 5-year study in a health maintenance organization. Am J Epidemiol. 1997;145:234-241.
2. Henke CE, Henke G, Elveback LR, Beard CM, Ballard DJ, Kurland LT. The epidemiology of sarcoidosis in Rochester, MN: a population-based study of incidence and survival. Am J Epidemiol. 1986; 123:840-845.
3. Wermers RA, Khosla S, Atkinson EJ, et al. 2006. Incidence of primary hyperparathyroidism in Rochester, MN, 1993-2001: an update on the changing epidemiology of the disease. J Bone Miner Res. 2006;21:171-177.
4. Snapper I, Yarvis JJ, Freund HR, Goldberg AF. Hyperparathyroidism in identical twins, one of whom suffered concomitantly of Boeck's sarcoidosis. Metabolism. 1958;7:671-680.
5. Fanconi A, Rose GA. The ionized, complexed, and protein-bound fractions of calcium in plasma: an investigation of patients with various diseases which affect calcium metabolism, with an additional study of the role of calcium ions in the prevention of tetany. Q J Med. 1958;27:463-494.
6. Yoshida T, Iwasaki Y, Kagawa T, et al. Coexisting primary hyperparathyroidism and sarcoidosis in a patient with severe hypercalcemia. Endocr J. 2008;55:391-395.
7. Balasanthiran A, Sandler B, Amonoo-Kuofi K, Swamy R, Kaniyur S, Kaplan F. Sarcoid granulomas in the parathyroid gland-a case of dual pathology: hypercalcaemia due to a parathyroid adenoma and coexistent sarcoidosis with granulomas located within the parathyroid adenoma and thyroid gland. Endocr J. 2010;57:603-607.
8. Hassan S, Amer S, Swamy V, Rao S. Sarcoidosis and primary hyperparathyroidism simultaneously occurring in a hypercalcemic patient. Indian J Endocrinol Metab. 2012;16:1062-1063.
9. Dent CE, Watson L. Hyperparathyroidism and sarcoidosis. Br Med J. 1966;1:646-649.
10. Lief PD, Bogartz LJ, Koerner SK, Buchberg AS. Sarcoidosis and primary hyperparathyroidism. An unusual association. Am J Med. 1969;47:825-830.
11. Bilezikian JP. Primary hyperparathyroidism. Endocr Pract. 2012; 18:781-790.
12. Harrell GT, Fisher S. Blood chemical changes in Boeck's sarcoidosis with particular reference to protein, calcium and phosphatase values. J Clin Invest. 1939;18:687-693.
13. Adams JS, Singer FR, Gacad MA, et al. Isolation and structural identification of 1,25-dihydroxyvitamin D3 produced by cultured alveolar macrophages in sarcoidosis. J Clin Endocrinol Metab. 1985;60:960-966.
14. Adams JS. Vitamin D metabolite-mediated hypercalcemia. Endocrinol Metab Clin North Am. 1989;18:765-778.
15. Dent CE. Some problems of hyperparathyroidism. Br Med J. 1956; 2:1419-1425.
16. Albright F, Carroll EL, Dempsey EF, Henneman PH. The cause of hypercalciuria in sarcoidosis and its treatment with cortisone and sodium phytate. J Clin Invest. 1956;35:1229-1242.
17. Burr JM, Farrell JJ, Hills AG. Special usefulness of the cortisone test. N Engl J Med. 1959;17:1271-1275.
18. Gwinup G, Sayle B. Cortisone responsive hypercalcemia in proved hyperparathyroidism. Ann Intern Med. 1961;55:1001-1004.
19. Dent CE. Some problems of hyperparathyroidism. Br Med J. 1962; 2:1495-1500.
20. Zeimer HJ, Greenaway TM, Slavin J, et al. Parathyroid hormonerelated protein in sarcoidosis. Am J Pathol. 1998;152:17-21.
21. Krikorian A, Shah S, Wasman J. Parathyroid hormone-related protein: an unusual mechanism for hypercalcemia in sarcoidosis. Endocr Pract. 2011;17:E84-E86.
22. Endres DB. Investigation of hypercalcemia. Clin Biochem. 2012; 45:954-963.
23. Fraser WD. Hyperparathyroidism. Lancet. 2009;374:145-158.
24. DeRemee RA, Lufkin EG, Rohrbach MS. Serum angiotensin-converting enzyme activity. Its use in the evaluation and management of hypercalcemia associated with sarcoidosis. Arch Intern Med. 1985; 145:677-679.
25. Kinoshita Y, Taguchi M, Takeshita A, Miura D, Tomikawa S, Takeuchi Y. 1,25-Dihydroxyvitam in Dsuppresses circulating levels of parathyroid hormone in a patient with primary hyperparathyroidism and coexistent sarcoidosis. J Clin Endocrinol Metab. 2005; 90:6727-6731.
26. Cushard WG Jr, Simon AB, Canterbury JM, Reiss E. Parathyroid function in sarcoidosis. N Engl J Med. 1972;286:395-398.
27. Falk S, Kratzsch J, Paschke R, Koch C. Hypercalcemia as a result of sarcoidosis with normal serum concentrations of vitamin D. Med Sci Monit. 2007;13:CS133-C136.
28. Unsal A, Basturk T, Koc Y, et al. Renal sarcoidosis with normal serum vitamin D and refractory hypercalcemia. Int Urol Nephrol. 2012 Jul 25. doi: 10.1007/s11255-012-0245-6.
29. Baughman RP, Teirstein AS, Judson MA, et al. Case Control Etiologic Study of Sarcoidosis (ACCESS) Research Group clinical characteristics of patients in a case control study of sarcoidosis. Am J Resp Crit Care Med. 2001;164:1885-1889.
30. James DG, Neville E, Siltzbach LE. A worldwide review of sarcoidosis. Ann NY Acad Sci. 1976;278:321-334.
31. Putkonen T, Hannuksela M, Halme H. Calcium and phosphorus metabolism in sarcoidosis. Acta Med Scand. 1965;177:327-335.