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Volumn 3, Issue 21, 2013, Pages 7739-7742

Lithium tert-butoxide mediated α-alkylation of ketones with primary alcohols under transition-metal-free conditions

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION REACTIONS; PRIMARY ALCOHOLS; TERT-BUTOXIDE; TRANSITION METAL CATALYSTS;

EID: 84877708693     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c3ra23221b     Document Type: Article
Times cited : (50)

References (57)
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    • D. Caine, in Comprehensive Organic Chemistry, ed., B. M. Trost, I. Fleming, and, G. Pattenden, Pergamon, Oxford, 1991, vol. 3, pp. 1-63
    • (1991) Comprehensive Organic Chemistry , vol.3 , pp. 1-63
    • Caine, D.1
  • 34
    • 84858987236 scopus 로고    scopus 로고
    • The contents of Ru, Ir, Pd, Ni, Ti, and Ag in the sublimed LiOtBu were all <0.1 ppm (ICP). On the other hand, different sources of LiOtBu were used with new glassware, almost the same results were obtained. These results amply indicated that this ketone-alcohol coupling is promoted by LiOtBu itself rather than catalyzed by the presence of trace metal impurities
    • Q. Li S. Fan Q. Sun H. Tian X. Yu Q. Xu Org. Biomol. Chem. 2012 10 2966
    • (2012) Org. Biomol. Chem. , vol.10 , pp. 2966
    • Li, Q.1    Fan, S.2    Sun, Q.3    Tian, H.4    Yu, X.5    Xu, Q.6
  • 47
    • 58049208387 scopus 로고    scopus 로고
    • For selected examples of base promoted reactions of ketones or alcohols under transition-metal-free conditions, see
    • R. Martínez D. J. Ramón M. Yus J. Org. Chem. 2008 73 9778
    • (2008) J. Org. Chem. , vol.73 , pp. 9778
    • Martínez, R.1    Ramón, D.J.2    Yus, M.3
  • 53
    • 65949102989 scopus 로고    scopus 로고
    • ref. 19 For selected examples of MOtBu promoted reactions under transition-metal-free conditions, see
    • J. Sedelmeier S. V. Ley I. R. Baxendale Green Chem. 2009 11 683
    • (2009) Green Chem. , vol.11 , pp. 683
    • Sedelmeier, J.1    Ley, S.V.2    Baxendale, I.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.