Spray dried inhalable ciprofloxacin powder with improved aerosolisation and antimicrobial activity

International Journal of Pharmaceutics

Volumn 449, Issue 1-2, 2013, Pages 44-58

  Osman, Rihab ^a,b   Kan, Pei Lee ^a   Awad, Gehanne ^b   Mortada, Nahed ^b   El Shamy, Abd Elhameed ^b   Alpar, Oya ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b African Union Organization St Abbassia   (Egypt)

Author keywords

Antibacterial activity; Dextran; Inhalable microparticles; Spray drying; Surface modifiers

Indexed keywords

ACETIC ACID; CHITOSAN; CIPROFLOXACIN; DEXTRAN; HYDROCHLORIC ACID;

ACIDITY; AEROSOL; ALKALINITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CELL VIABILITY; DRUG CYTOTOXICITY; DRUG FORMULATION; DRUG RELEASE; DRUG SAFETY; HYDROGEN BOND; INFRARED SPECTROSCOPY; LUNG ALVEOLUS EPITHELIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SPRAY DRYING; THERMAL ANALYSIS; THERMOSTABILITY; VAPOR PRESSURE;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ADMINISTRATION, INHALATION; AEROSOLS; ANTI-BACTERIAL AGENTS; CELL LINE; CHITOSAN; CIPROFLOXACIN; DEXTRANS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; EXCIPIENTS; HUMANS; HYDROGEN-ION CONCENTRATION; LUNG; MICROSPHERES; POLYETHYLENE GLYCOLS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 84877693370     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.009     Document Type: Article

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