Alpha1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor

Biochemical and Biophysical Research Communications

Volumn 433, Issue 2, 2013, Pages 188-193

  O Uchi, Jin ^a,b   Komukai, Kimiaki ^b   Kusakari, Yoichiro ^b   Morimoto, Satoshi ^b   Kawai, Makoto ^b   Jhun, Bong Sook ^a   Hurst, Stephen ^a   Hongo, Kenichi ^b   Sheu, Shey Shing ^a   Kurihara, Satoshi ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adrenergic receptor; CAMP; G protein

Indexed keywords

ADENYLATE CYCLASE; ALPHA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR; CALCIUM ION; CYCLIC AMP; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; PHENYLEPHRINE; PROPANOLAMINE DERIVATIVE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVATION; EXCITATION CONTRACTION COUPLING; HEART CONTRACTION; HEART MUSCLE CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CALCIUM SIGNALING; CYTOSOL; DRUG EFFECT; HEART PAPILLARY MUSCLE; HEART VENTRICLE; HUMAN; METABOLISM; PATCH CLAMP; PHOSPHORYLATION; PHYSIOLOGY;

ADENYLATE CYCLASE; ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CALCIUM SIGNALING; CYTOSOL; EXCITATION CONTRACTION COUPLING; HEART VENTRICLES; HUMANS; ISOPROTERENOL; MYOCYTES, CARDIAC; PAPILLARY MUSCLES; PATCH-CLAMP TECHNIQUES; PHENYLEPHRINE; PHOSPHORYLATION; PROPANOLAMINES; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA-1; TYROSINE;

MLCS; MLOWN;

EID: 84877669148     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.02.072     Document Type: Article

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