-
1
-
-
1542608515
-
In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype
-
Ramakers-van Woerden NL, Beverloo HB, Veerman AJ, Camitta BM, Loonen AH, van Wering ER et al. In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype. Leukemia 2004; 18: 521-529.
-
(2004)
Leukemia
, vol.18
, pp. 521-529
-
-
Ramakers-Van Woerden, N.L.1
Beverloo, H.B.2
Veerman, A.J.3
Camitta, B.M.4
Loonen, A.H.5
Van Wering, E.R.6
-
2
-
-
0031717981
-
Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia-implications for treatment of infants
-
Pieters R, den Boer ML, Durian M, Janka G, Schmiegelow K, Kaspers GJ et al. Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia-implications for treatment of infants. Leukemia 1998; 12: 1344-1348.
-
(1998)
Leukemia
, vol.12
, pp. 1344-1348
-
-
Pieters, R.1
Den Boer, M.L.2
Durian, M.3
Janka, G.4
Schmiegelow, K.5
Kaspers, G.J.6
-
3
-
-
0344246893
-
Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia
-
Dordelmann M, Reiter A, Borkhardt A, Ludwig WD, Gotz N, Viehmann S et al. Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia. Blood 1999; 94: 1209-1217.
-
(1999)
Blood
, vol.94
, pp. 1209-1217
-
-
Dordelmann, M.1
Reiter, A.2
Borkhardt, A.3
Ludwig, W.D.4
Gotz, N.5
Viehmann, S.6
-
4
-
-
34447519040
-
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): An observational study and a multicentre randomised trial
-
Pieters R, Schrappe M, De Lorenzo P, Hann I, De Rossi G, Felice M et al. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial. Lancet 2007; 370: 240-250.
-
(2007)
Lancet
, vol.370
, pp. 240-250
-
-
Pieters, R.1
Schrappe, M.2
De Lorenzo, P.3
Hann, I.4
De Rossi, G.5
Felice, M.6
-
5
-
-
0141799965
-
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia
-
Den Boer ML, Harms DO, Pieters R, Kazemier KM, Gobel U, Korholz D et al. Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol 2003; 21: 3262-3268.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3262-3268
-
-
Den Boer, M.L.1
Harms, D.O.2
Pieters, R.3
Kazemier, K.M.4
Gobel, U.5
Korholz, D.6
-
6
-
-
0032126675
-
Prednisolone resistance in childhood acute lymphoblastic leukemia: Vitro-vivo correlations and cross-resistance to other drugs
-
Kaspers GJ, Pieters R, Van Zantwijk CH, Van Wering ER, Van Der Does-Van Den Berg A, Veerman AJ. Prednisolone resistance in childhood acute lymphoblastic leukemia: vitro-vivo correlations and cross-resistance to other drugs. Blood 1998; 92: 259-266.
-
(1998)
Blood
, vol.92
, pp. 259-266
-
-
Kaspers, G.J.1
Pieters, R.2
Van Zantwijk, C.H.3
Van Wering, E.R.4
Van Der Does-Van Den Berg, A.5
Veerman, A.J.6
-
7
-
-
77649213702
-
Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia
-
Stam RW, Den Boer ML, Schneider P, de Boer J, Hagelstein J, Valsecchi MG et al. Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia. Blood 2010; 115: 1018-1025.
-
(2010)
Blood
, vol.115
, pp. 1018-1025
-
-
Stam, R.W.1
Den Boer, M.L.2
Schneider, P.3
De Boer, J.4
Hagelstein, J.5
Valsecchi, M.G.6
-
8
-
-
70350569248
-
Overexpression of Annexin II affects the proliferation, apoptosis, invasion and production of proangiogenic factors in multiple myeloma
-
Bao H, Jiang M, Zhu M, Sheng F, Ruan J, Ruan C. Overexpression of Annexin II affects the proliferation, apoptosis, invasion and production of proangiogenic factors in multiple myeloma. Int J Hematol 2009; 90: 177-185.
-
(2009)
Int J Hematol
, vol.90
, pp. 177-185
-
-
Bao, H.1
Jiang, M.2
Zhu, M.3
Sheng, F.4
Ruan, J.5
Ruan, C.6
-
9
-
-
70449433807
-
Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells
-
Zhang F, Zhang L, Zhang B, Wei X, Yang Y, Qi RZ et al. Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. J Proteome Res 2009; 8: 5041-5047.
-
(2009)
J Proteome Res
, vol.8
, pp. 5041-5047
-
-
Zhang, F.1
Zhang, L.2
Zhang, B.3
Wei, X.4
Yang, Y.5
Qi, R.Z.6
-
10
-
-
67549130802
-
Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth
-
Braden AR, Kafka MT, Cunningham L, Jones H, Vishwanatha JK. Polymeric nanoparticles for sustained down-regulation of annexin A2 inhibit prostate tumor growth. J Nanosci Nanotechnol 2009; 9: 2856-2865.
-
(2009)
J Nanosci Nanotechnol
, vol.9
, pp. 2856-2865
-
-
Braden, A.R.1
Kafka, M.T.2
Cunningham, L.3
Jones, H.4
Vishwanatha, J.K.5
-
11
-
-
79955775515
-
Tyrosine 23 phosphorylation- dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer
-
Zheng L, Foley K, Huang L, Leubner A, Mo G, Olino K et al. Tyrosine 23 phosphorylation- dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS One 2011; 6: e19390.
-
(2011)
PLoS One
, vol.6
-
-
Zheng, L.1
Foley, K.2
Huang, L.3
Leubner, A.4
Mo, G.5
Olino, K.6
-
12
-
-
65649136205
-
Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation
-
Hayes MJ, Moss SE. Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation. J Biol Chem 2009; 284: 10202-10210.
-
(2009)
J Biol Chem
, vol.284
, pp. 10202-10210
-
-
Hayes, M.J.1
Moss, S.E.2
-
13
-
-
50349088997
-
Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11
-
He KL, Deora AB, Xiong H, Ling Q, Weksler BB, Niesvizky R et al. Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. J Biol Chem 2008; 283: 19192-19200.
-
(2008)
J Biol Chem
, vol.283
, pp. 19192-19200
-
-
He, K.L.1
Deora, A.B.2
Xiong, H.3
Ling, Q.4
Weksler, B.B.5
Niesvizky, R.6
-
14
-
-
77149148713
-
The endothelial cell annexin A2 system and vascular fibrinolysis
-
Spec No Focus F20-F28
-
Dassah M, Deora AB, He K, Hajjar KA. The endothelial cell annexin A2 system and vascular fibrinolysis. Gen Physiol Biophys 2009; 28: Spec No Focus F20-F28.
-
(2009)
Gen Physiol Biophys
, vol.28
-
-
Dassah, M.1
Deora, A.B.2
He, K.3
Hajjar, K.A.4
-
15
-
-
0028032922
-
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay
-
Kaspers GJ, Veerman AJ, Pieters R, Broekema GJ, Huismans DR, Kazemier KM et al. Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay. Br J Cancer 1994; 70: 1047-1052.
-
(1994)
Br J Cancer
, vol.70
, pp. 1047-1052
-
-
Kaspers, G.J.1
Veerman, A.J.2
Pieters, R.3
Broekema, G.J.4
Huismans, D.R.5
Kazemier, K.M.6
-
16
-
-
0025201303
-
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions
-
Pieters R, Loonen AH, Huismans DR, Broekema GJ, Dirven MW, Heyenbrok MW et al. In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions. Blood 1990; 76: 2327-2336.
-
(1990)
Blood
, vol.76
, pp. 2327-2336
-
-
Pieters, R.1
Loonen, A.H.2
Huismans, D.R.3
Broekema, G.J.4
Dirven, M.W.5
Heyenbrok, M.W.6
-
17
-
-
84862009683
-
Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia
-
Spijkers-Hagelstein JA, Schneider P, Hulleman E, de Boer J, Williams O, Pieters R et al. Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia. Leukemia 2012; 26: 1255-1265.
-
(2012)
Leukemia
, vol.26
, pp. 1255-1265
-
-
Spijkers-Hagelstein, J.A.1
Schneider, P.2
Hulleman, E.3
De Boer, J.4
Williams, O.5
Pieters, R.6
-
18
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc Ser B. 1995; 57: 289-300.
-
(1995)
J Roy Stat Soc ser B.
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
-
19
-
-
33646361583
-
GenePattern 2.0
-
Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP. GenePattern 2.0. Nat Genet 2006; 38: 500-501.
-
(2006)
Nat Genet
, vol.38
, pp. 500-501
-
-
Reich, M.1
Liefeld, T.2
Gould, J.3
Lerner, J.4
Tamayo, P.5
Mesirov, J.P.6
-
20
-
-
27144499798
-
Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia
-
Stam RW, den Boer ML, Schneider P, Nollau P, Horstmann M, Beverloo HB et al. Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia. Blood 2005; 106: 2484-2490.
-
(2005)
Blood
, vol.106
, pp. 2484-2490
-
-
Stam, R.W.1
Den Boer, M.L.2
Schneider, P.3
Nollau, P.4
Horstmann, M.5
Beverloo, H.B.6
-
21
-
-
0033200390
-
Structural basis for selective inhibition of Src family kinases by PP1
-
Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J et al. Structural basis for selective inhibition of Src family kinases by PP1. Chem Biol 1999; 6: 671-678.
-
(1999)
Chem Biol
, vol.6
, pp. 671-678
-
-
Liu, Y.1
Bishop, A.2
Witucki, L.3
Kraybill, B.4
Shimizu, E.5
Tsien, J.6
-
22
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
-
Hanke JH, Gardner JP, Dow RL, Changelian PS, Brissette WH, Weringer EJ et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem1996; 271: 695-701.
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
-
23
-
-
1542269021
-
Tyrosine kinase inhibitors: A new approach for asthma
-
Wong WS, Leong KP. Tyrosine kinase inhibitors: a new approach for asthma. Biochim Biophys Acta 2004; 1697: 53-69.
-
(2004)
Biochim Biophys Acta
, vol.1697
, pp. 53-69
-
-
Wong, W.S.1
Leong, K.P.2
-
25
-
-
79952749162
-
Dasatinib: An anti-tumour agent via Src inhibition
-
Gnoni A, Marech I, Silvestris N, Vacca A, Lorusso V. Dasatinib: an anti-tumour agent via Src inhibition. Curr Drug Targets 2011; 12: 563-578.
-
(2011)
Curr Drug Targets
, vol.12
, pp. 563-578
-
-
Gnoni, A.1
Marech, I.2
Silvestris, N.3
Vacca, A.4
Lorusso, V.5
-
26
-
-
77950966577
-
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants
-
Stam RW, Schneider P, Hagelstein JA, van der Linden MH, Stumpel DJ, de Menezes RX et al. Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants. Blood 2010; 115: 2835-2844.
-
(2010)
Blood
, vol.115
, pp. 2835-2844
-
-
Stam, R.W.1
Schneider, P.2
Hagelstein, J.A.3
Van Der Linden, M.H.4
Stumpel, D.J.5
De Menezes, R.X.6
-
27
-
-
33847210356
-
Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD
-
Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A et al. Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. Leukemia 2007; 21: 403-410.
-
(2007)
Leukemia
, vol.21
, pp. 403-410
-
-
Okamoto, M.1
Hayakawa, F.2
Miyata, Y.3
Watamoto, K.4
Emi, N.5
Abe, A.6
-
28
-
-
84855748821
-
Phase II trial of saracatinib (AZD0530), an oral src-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer
-
Gucalp A, Sparano JA, Caravelli J, Santamauro J, Patil S, Abbruzzi A et al. Phase II trial of saracatinib (AZD0530), an oral src-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. Clin Breast Cancer 2011; 11: 306-311.
-
(2011)
Clin Breast Cancer
, vol.11
, pp. 306-311
-
-
Gucalp, A.1
Sparano, J.A.2
Caravelli, J.3
Santamauro, J.4
Patil, S.5
Abbruzzi, A.6
-
29
-
-
84863792706
-
A phase II trial of the Src kinase inhibitor saracatinib (AZD0530) in patients with metastatic or locally advanced gastric or gastro esophageal junction (GEJ) adenocarcinoma: A trial of the PMH phase II consortium
-
Mackay HJ, Au HJ, McWhirter E, Alcindor T, Jarvi A, Macalpine K et al. A phase II trial of the Src kinase inhibitor saracatinib (AZD0530) in patients with metastatic or locally advanced gastric or gastro esophageal junction (GEJ) adenocarcinoma: a trial of the PMH phase II consortium. Invest New Drugs 2012; 30: 1158-1163.
-
(2012)
Invest New Drugs
, vol.30
, pp. 1158-1163
-
-
Mackay, H.J.1
Au, H.J.2
McWhirter, E.3
Alcindor, T.4
Jarvi, A.5
Macalpine, K.6
-
30
-
-
79851495693
-
Phase II study of saracatinib (AZD0530) for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)
-
Fury MG, Baxi S, Shen R, Kelly KW, Lipson BL, Carlson D et al. Phase II study of saracatinib (AZD0530) for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). Anticancer Res 2011; 31: 249-253.
-
(2011)
Anticancer Res
, vol.31
, pp. 249-253
-
-
Fury, M.G.1
Baxi, S.2
Shen, R.3
Kelly, K.W.4
Lipson, B.L.5
Carlson, D.6
-
31
-
-
84862018553
-
A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer
-
Renouf DJ, Moore MJ, Hedley D, Gill S, Jonker D, Chen E et al. A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer. Invest New Drugs 2012; 30: 779-786.
-
(2012)
Invest New Drugs
, vol.30
, pp. 779-786
-
-
Renouf, D.J.1
Moore, M.J.2
Hedley, D.3
Gill, S.4
Jonker, D.5
Chen, E.6
-
32
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, Buchdunger E, Warmuth M, Fabbro D et al. Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 2004; 36: 453-461.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
Buchdunger, E.4
Warmuth, M.5
Fabbro, D.6
-
33
-
-
29144464371
-
Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia
-
Manley PW, Cowan-Jacob SW, Mestan J. Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia. Biochim Biophys Acta 2005; 1754: 3-13.
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 3-13
-
-
Manley, P.W.1
Cowan-Jacob, S.W.2
Mestan, J.3
-
34
-
-
54549083228
-
H3K79 methylation profiles define murine and human MLL-AF4 leukemias
-
Krivtsov AV, Feng Z, Lemieux ME, Faber J, Vempati S, Sinha AU et al. H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer Cell 2008; 14: 355-368.
-
(2008)
Cancer Cell
, vol.14
, pp. 355-368
-
-
Krivtsov, A.V.1
Feng, Z.2
Lemieux, M.E.3
Faber, J.4
Vempati, S.5
Sinha, A.U.6
-
35
-
-
79953793973
-
Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5- phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction
-
Reddy TR, Li C, Guo X, Myrvang HK, Fischer PM, Dekker LV. Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5- phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction. J Med Chem 2011; 54: 2080-2094.
-
(2011)
J Med Chem
, vol.54
, pp. 2080-2094
-
-
Reddy, T.R.1
Li, C.2
Guo, X.3
Myrvang, H.K.4
Fischer, P.M.5
Dekker, L.V.6
|