Genomic abnormalities of waldenström macroglobulinemia and related low-grade B-cell lymphomas

Clinical Lymphoma, Myeloma and Leukemia

Volumn 13, Issue 2, 2013, Pages 198-201

  Braggio, Esteban ^a   Fonseca, Rafael ^a  

^a MAYO CLINIC   (United States)

Author keywords

Array based comparative genomic hybridization; Low grade B cell lymphomas; Nuclear factor kappa B signaling pathway; Waldenstr m macroglobulinemia

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN M; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88;

BONE MARROW BIOPSY; CHROMOSOME ABERRATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONFERENCE PAPER; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; MARGINAL ZONE LYMPHOMA; MONOCLONAL IMMUNOGLOBULINEMIA; PARTIAL TRISOMY 4; SIGNAL TRANSDUCTION; WALDENSTROEM MACROGLOBULINEMIA;

CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; DNA COPY NUMBER VARIATIONS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; LYMPHOMA, B-CELL; WALDENSTROM MACROGLOBULINEMIA;

EID: 84877603050     PISSN: 21522650     EISSN: 21522669     Source Type: Journal    
DOI: 10.1016/j.clml.2013.02.015     Document Type: Conference Paper

References (23)

1. E. Braggio, J.J. Keats, X. Leleu Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia Cancer Res 69 2009 3579 3588
2. E. Braggio, J.J. Keats, X. Leleu High-resolution genomic analysis in Waldenström's macroglobulinemia identifies disease-specific and common abnormalities with marginal zone lymphomas Clin Lymphoma Myeloma 9 2009 39 42
3. F. Nguyen-Khac, J. Lejeune, E. Chapiro Cytogenetic abnormalities in a cohort of 171 patients with Waldenström macroglobulinemia before treatment: clinical and biological correlations Blood (ASH annual meeting abstracts) 116 2010 Abstract 801
4. R.F. Schop, S.M. Jalal, S.A. Van Wier Deletions of 17p13.1 and 13q14 are uncommon in Waldenström macroglobulinemia clonal cells and mostly seen at the time of disease progression Cancer Genet Cytogenet 132 2002 55 60 (Pubitemid 34136052)
5. R.F. Schop, W.M. Kuehl, S.A. Van Wier Waldenström macroglobulinemia neoplastic cells lack immunoglobulin heavy chain locus translocations but have frequent 6q deletions Blood 100 2002 2996 3001
6. C. Terré, F. Nguyen-Khac, C. Barin Trisomy 4, a new chromosomal abnormality in Waldenström's macroglobulinemia: a study of 39 cases Leukemia 20 2006 1634 1636 (Pubitemid 44264115)
7. S.P. Treon, L. Xu, G. Yang MYD88 L265P somatic mutation in Waldenström's macroglobulinemia N Engl J Med 367 2012 826 833
8. W.J. Chng, R.F. Schop, T. Price-Troska Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma Blood 108 2006 2755 2763
9. N.C. Gutiérrez, E.M. Ocio, J. de las Rivas Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals Leukemia 21 2007 541 549
10. R.G. Owen, S.P. Treon, A. Al-Katib Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia Semin Oncol 30 2003 110 115 (Pubitemid 36506291)
11. E. Braggio, A. Dogan, J.J. Keats Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities Mod Pathol 25 2012 651 660
12. B.I. Ferreira, J.F. García, J. Suela Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasia Haematologica 93 2008 670 679 (Pubitemid 351669306)
13. M. Compagno, W.K. Lim, A. Grunn Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma Nature 459 2009 717 721
14. E. Chanudet, H. Ye, J. Ferry A20 deletion is associated with copy number gain at the TNFA/B/C locus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands J Pathol 217 2009 420 430
15. K. Honma, S. Tsuzuki, M. Nakagawa TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas Blood 114 2009 2467 2475
16. R. Schmitz, M.L. Hansmann, V. Bohle TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma J Exp Med 206 2009 981 989
17. M. Kato, M. Sanada, I. Kato Frequent inactivation of A20 in B-cell lymphomas Nature 459 2009 712 716
18. G.A. Calin, C.D. Dumitru, M. Shimizu Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia Proc Natl Acad Sci U S A 99 2002 15524 15529 (Pubitemid 35403967)
19. J.J. Keats, R. Fonseca, M. Chesi Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma Cancer Cell 12 2007 131 144 (Pubitemid 47208626)
20. C.M. Annunziata, R.E. Davis, Y. Demchenko Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma Cancer Cell 12 2007 115 130 (Pubitemid 47199123)
21. M.L. McMaster, L.R. Goldin, Y. Bai Genomewide linkage screen for Waldenstrom macroglobulinemia susceptibility loci in high-risk families Am J Hum Genet 79 2006 695 701 (Pubitemid 44452746)
22. C. Largo, B. Saéz, S. Alvarez Multiple myeloma primary cells show a highly rearranged unbalanced genome with amplifications and homozygous deletions irrespective of the presence of immunoglobulin-related chromosome translocations Haematologica 92 2007 795 802 (Pubitemid 350155305)
23. E.M. Hartmann, E. Campo, G. Wright Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling Blood 116 2010 953 961