The role of the mTOR pathway during liver regeneration and tumorigenesis

Annales d'Endocrinologie

Volumn 74, Issue 2, 2013, Pages 121-122

  Panasyuk, Ganna ^a   Patitucci, Cecilia ^a   Espeillac, Catherine ^a   Pende, Mario ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEXOKINASE; HEXOKINASE 2; MAMMALIAN TARGET OF RAPAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B BETA; PYRUVATE KINASE; PYRUVATE KINASE M2; S6 KINASE; UNCLASSIFIED DRUG;

ARTICLE; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FATTY LIVER; GLYCOLYSIS; HUMAN; INFLAMMATION; LIVER CELL CARCINOMA; LIVER HYPERPLASIA; LIVER HYPERTROPHY; LIVER REGENERATION; NONHUMAN; OBESITY; OVERNUTRITION; PARTIAL HEPATECTOMY; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RISK FACTOR;

EID: 84877596524     PISSN: 00034266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ando.2013.03.003     Document Type: Article

References (4)

1. Espeillac C., Mitchell C., Celton-Morizur S., Chauvin C., Koka V., Gillet C., et al. S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy. J Clin Invest 2011, 121:2821-2832.
2. Laplante M., Sabatini D.M. mTOR signaling in growth control and disease. Cell 2012, 149:274-293.
3. Panasyuk G., Espeillac C., Chauvin C., Pradelli L.A., Horie Y., Suzuki A., et al. PPARgamma contributes to PKM2 and HK2 expression in fatty liver. Nat Commun 2012, 3:672.
4. Park E.J., Lee J.H., Yu G.Y., He G., Ali S.R., Holzer R.G., et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010, 140:197-208.