A fatal case of Naegleria fowleri meningoencephalitis in Taiwan

Korean Journal of Parasitology

Volumn 51, Issue 2, 2013, Pages 203-206

  Su, Mei Yu ^a   Lee, Ming Shih ^a,b   Shyu, Ling Yuh ^b   Lin, Wei Chen ^c   Hsiao, Pei Ching ^a   Wang, Chi Ping ^a,b   Ji, Dar Der ^c,d   Chen, Ke Min ^b   Lai, Shih Chan ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CENTER FOR DISEASE CONTROL   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Amphotericin B; Fatal case; Meningoencephalitis; Naegleria fowleri; Taiwan

Indexed keywords

AMPHOTERICIN B; C REACTIVE PROTEIN; GLUCOSE; NITROGEN; PROTOZOAL DNA; UREA;

AGED; ARTICLE; CASE REPORT; CAUSE OF DEATH; CEREBROSPINAL FLUID CULTURE; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONSCIOUSNESS DISORDER; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CONVULSION; DISEASE SEVERITY; FATALITY; GENE SEQUENCE; GLUCOSE BLOOD LEVEL; HUMAN; LEUKOCYTE COUNT; LIMB WEAKNESS; MULTIPLE ORGAN FAILURE; NAEGLERIA FOWLERI; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARASITE IDENTIFICATION; POLYMERASE CHAIN REACTION; PRIMARY AMEBIC MENINGOENCEPHALITIS; PSEUDOPODIUM; TAIWAN; THERMAL SPRING; THROMBOCYTE COUNT; TROPHOZOITE;

AMPHOTERICIN B; FATAL CASE; MENINGOENCEPHALITIS; NAEGLERIA FOWLERI; TAIWAN;

AGED; AMEBIASIS; CENTRAL NERVOUS SYSTEM PROTOZOAL INFECTIONS; CEREBROSPINAL FLUID; DNA, PROTOZOAN; FATAL OUTCOME; HUMANS; MALE; MICROSCOPY; NAEGLERIA FOWLERI; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TAIWAN;

EID: 84877587980     PISSN: 00234001     EISSN: 17380006     Source Type: Journal    
DOI: 10.3347/kjp.2013.51.2.203     Document Type: Article

References (13)

1. Schuster FL, Visvesvara GS. Free-living amoebae as opportunistic and non-opportunistic pathogens of humans and animals. Int J Parasitol 2004; 34: 1001-1027.
2. Visvesvara GS, Moura H, Schuster FL. Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 2007; 50: 1-26.
3. da Rocha-Azevedo B, Tanowitz HB, Marciano-Cabral F. Diagnosis of infections caused by pathogenic free-living amoebae. Interdiscip Perspect Infect Dis 2009; 251406: 1-14.
4. Heggie TW. Swimming with death: Naegleria fowleri infections in recreational waters. Travel Med Infect Dis 2010; 8: 201-206.
5. Martinez AJ, Visvesvara GS. Free-living, amphizoic and opportunistic amebas. Brain Pathol 1997; 7: 583-598.
6. Schild M, Gianinazzi C, Gottstein B, Müller N. PCR-based diagnosis of Naegleria sp. infection in formalin-fixed and paraffinembedded brain sections. J Clin Microbiol 2007; 45: 564-567.
7. Qvarnstrom Y, Visvesvara GS, Sriram R, da Silva AJ. Multiplex real-time PCR assay for simultaneous detection of Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri. J Clin Microbiol 2006; 44: 3589-3595.
8. de Jonckheere J, Voorde H. The distribution of Naegleria fowleri in man-made thermal waters. Am J Trop Med Hyg 1977; 26: 10-15.
9. Tyndall RL, Ironside KS, Metler PL, Tan EL, Hazen TC, Fliermans CB. Effect of thermal additions on the density and distribution of thermophilic amoebae and pathogenic Naegleria fowleri in a newly created cooling lake. Appl Environ Microbiol 1989; 55: 722-732.
10. Kidney DD, Kim SH. CNS infections with free-living amebas: neuroimaging findings. AJR Am J Roentgenol 1998; 171: 809-812.
11. Schumacher DJ, Tien RD, Lane K. Neuroimaging findings in rare amebic infections of the central nervous system. AJNR Am J Neuroradiol 1995; 16: 930-935.
12. Carter RF. Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis. J Clin Pathol 1969; 22: 470-474.
13. Vargas-Zepeda J, Gómez-Alcalá AV, Vásquez-Morales JA, Licea-Amaya L, De Jonckheere JF, Lares-Villa F. Successful treatment of Naegleria fowleri meningoencephalitis by using intravenous amphotericin B, fluconazole and rifampicin. Arch Med Res 2005; 36: 83-86.