Is stereotactic body radiation therapy an attractive option for unresectable liver metastases? A preliminary report from a phase 2 trial

International Journal of Radiation Oncology Biology Physics

Volumn 86, Issue 2, 2013, Pages 336-342

  Scorsetti, Marta ^a   Arcangeli, Stefano ^a   Tozzi, Angelo ^a   Comito, Tiziana ^a   Alongi, Filippo ^a   Navarria, Pierina ^a   Mancosu, Pietro ^a   Reggiori, Giacomo ^a   Fogliata, Antonella ^b   Torzilli, Guido ^a   Tomatis, Stefano ^a   Cozzi, Luca ^b  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOSE PRESCRIPTION; KARNOFSKY PERFORMANCE STATUS; LIVER METASTASIS; METHODS AND MATERIALS; OVERALL SURVIVAL RATES; RADIATION-INDUCED LIVER DISEASE; STEREOTACTIC BODY RADIATION THERAPY; VOLUMETRIC MODULATED ARC THERAPY;

NONINVASIVE MEDICAL PROCEDURES; POINT CONTACTS; RADIOTHERAPY; TOXICITY;

PATHOLOGY;

ACUTE TOXICITY; ADULT; AGED; ARTICLE; BREAST CANCER; CANCER LOCALIZATION; CANCER SURVIVAL; CLINICAL EVALUATION; COLORECTAL CANCER; FATIGUE; FEASIBILITY STUDY; FEMALE; HUMAN; KARNOFSKY PERFORMANCE STATUS; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PATIENT SAFETY; PHASE 2 CLINICAL TRIAL; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; STEREOTACTIC BODY RADIATION THERAPY; THORAX PAIN; TREATMENT RESPONSE; TUMOR VOLUME;

ADULT; AGED; AGED, 80 AND OVER; FEASIBILITY STUDIES; FEMALE; HUMANS; KARNOFSKY PERFORMANCE STATUS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RADIOSURGERY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED; TUMOR BURDEN;

EID: 84877583726     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.12.021     Document Type: Article

References (21)

1. S.A. Shah, R. Bromberg, and A. Coates Survival after liver resection for metastatic colorectal carcinoma in a large population J Am Coll Surg 205 2007 676 683
2. S. Garrean, J. Hering, A. Saied, W.S. Helton, and N.J. Espat Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature Am J Surg 195 2008 508 520
3. L.A. Dawson, D. Normolle, and J.M. Balter Analysis of radiation-induced liver disease using the Lyman NTCP model Int J Radiat Oncol Biol Phys 53 2002 810 821
4. R.D. Timmerman, B.D. Kavanagh, and L.C. Cho Stereotactic body radiation therapy in multiple organ sites J Clin Oncol 25 2007 947 952
5. T.E. Schefter, and B.D. Kavanagh Radiation therapy for liver metastases Semin Radiat Oncol 21 2011 264 270 Review Erratum in: Semin Radiat Oncol 2012;22(1):86.
6. E. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumors: revised RECIST guideline (version 1.1) Eur J Cancer 45 2009 228 247
7. D.T. Chang, A. Swaminath, and M. Kozak Stereotactic body radiotherapy for colorectal liver metastases: a pooled analysis Cancer 117 2011 4060 4069
8. K.K. Herfarth, J. Debus, and M. Wannenmacher Stereotactic radiation therapy of liver metastases: Update of the initial phase-I/ II trial Front Radiat Ther Oncol 38 2004 100 105
9. M.T. Lee, J.J. Kim, and R. Dinniwell Phase I study of individualized stereotactic body radiotherapy of liver metastases J Clin Oncol 27 2009 1585 1591
10. K.A. Goodman, E.A. Wiegner, and K.E. Maturen Dose-escalation study of single-fraction stereotactic body radiotherapy for liver malignancies Int J Radiat Oncol Biol Phys 78 2010 486 493
11. K.E. Rusthoven, B.D. Kavanagh, and H. Cardenes Multi-institutional phase I/II trial of stereotactic body radiation therapy for liver metastases J Clin Oncol 27 2009 1572 1578
12. G. Ambrosino, F. Polistina, and G. Costantin Image-guided robotic stereotactic radiosurgery for unresectable liver metastases: Preliminary results Anticancer Res 29 2009 3381 3384
13. F. Alongi, S. Arcangeli, and A.R. Filippi Review and uses of stereotactic body radiation therapy for oligometastases Oncologist 17 2012 1100 1107
14. Radiofrequency Ablation Versus Stereotactic Radiotherapy in Colorectal Liver Metastases (RAS01). ClinicalTrials.gov NCT01233544. Last Updated: March 20, 2012.
15. Z. Fuks, and R. Kolesnick Engaging the vascular component of the tumor response Cancer Cell 8 2005 89 91
16. D.W. Kim, J. Huamani, and K.J. Niermann Noninvasive assessment of tumor vasculature response to radiation-mediated, vasculature-targeted therapy using quantified power Doppler sonography: Implications for improvement of therapy schedules J Ultrasound Med 25 2006 1507 1517
17. G. Kragl, F. Baier, and S. Lutz flattening filter free beams in SBRT and IMRT: dosimetric assessment of peripheral doses Med Phys 21 2011 91 101
18. N. Dunlap, G. Biederman, and W. Yang Chest wall volume receiving more than 30 Gy predicts risk of severe pain and/or rib fracture after lung SBRT Int J Radiat Oncol Biol Phys 72 Suppl 36 2008 796 801
19. Sorafenib-RT Treatment for Liver Metastasis (SLIM). ClinicalTrials.gov NCT00892424. Last Updated: February 11, 2011.
20. A. Mendez Romero, W. Wunderink, and R.M. van Os Quality of life after stereotactic body radiation therapy for primary and metastatic liver tumors Int J Radiat Oncol Biol Phys 70 2008 1447 1452
21. M. Hoyer, H. Roed, and H.A. Traberg Phase II study on stereotactic body radiotherapy of colorectal metastases Acta Oncol 45 2006 823 830