Motion interplay as a function of patient parameters and spot size in spot scanning proton therapy for lung cancer

International Journal of Radiation Oncology Biology Physics

Volumn 86, Issue 2, 2013, Pages 380-386

  Grassberger, Clemens ^a,b   Dowdell, Stephen ^a   Lomax, Antony ^b   Sharp, Greg ^a   Shackleford, James ^a   Choi, Noah ^a   Willers, Henning ^a   Paganetti, Harald ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CONVENTIONAL FRACTIONATIONS; DOSE DISTRIBUTIONS; METHODS AND MATERIALS; MONTE CARLO SIMULATIONS; MOTION AMPLITUDES; PATIENT PARAMETERS; RESPIRATORY MOTIONS; SIGNIFICANT DETERIORATIONS;

DETERIORATION; MONTE CARLO METHODS; NORMAL DISTRIBUTION; PROTON BEAMS; RESPIRATORY MECHANICS; TUMORS;

BIOLOGICAL ORGANS;

ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SIZE; CLINICAL ARTICLE; HUMAN; LUNG CANCER; MONTE CARLO METHOD; PRIORITY JOURNAL; PROTON THERAPY; RADIATION DOSE DISTRIBUTION; RADIATION DOSE FRACTIONATION;

DOSE FRACTIONATION; HUMANS; LUNG; LUNG NEOPLASMS; MONTE CARLO METHOD; MOVEMENT; PROTON THERAPY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RELATIVE BIOLOGICAL EFFECTIVENESS; RESPIRATION; RETROSPECTIVE STUDIES; TIME FACTORS; TUMOR BURDEN;

EID: 84877579543     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.01.024     Document Type: Article

References (15)

1. R. Timmerman, R. Paulus, and J. Galvin Stereotactic body radiation therapy for inoperable early stage lung cancer JAMA 303 2010 1070 1076
2. A. Jemal, R. Siegel, and E. Ward Cancer Statistics, 2008 Cancer 58 2008 71 96
3. J.Y. Chang, R. Komaki, and H.Y. Wen Toxicity and patterns of failure of adaptive/ablative proton therapy for early-stage, medically inoperable non-small cell lung cancer Int J Radiat Oncol Biol Phys 80 2011 1350 1357
4. J.Y. Chang, R. Komaki, and C. Lu Phase 2 study of high-dose proton therapy with concurrent chemotherapy for unresectable stage III nonsmall cell lung cancer Cancer 117 2011 4707 4713
5. X. Zhang, Y. Li, and X. Pan Intensity-modulated proton therapy reduces the dose to normal tissue compared with intensity-modulated radiation therapy or passive scattering proton therapy and enables individualized radical radiotherapy for extensive stage IIIB non-small-cell lung cancer: A virtual clinical study Int J Radiat Oncol Biol Phys 77 2010 357 366
6. A.-C. Knopf, T.S. Hong, and A. Lomax Scanned proton radiotherapy for mobile targets-the effectiveness of re-scanning in the context of different treatment planning approaches and for different motion characteristics Phys Med Biol 56 2011 7257 7271
7. C. Bert, S.O. Grozinger, and E. Rietzel Quantification of interplay effects of scanned particle beams and moving targets Phys Med Biol 53 2008 2253 2265
8. K.M. Kraus, E. Heath, and U. Oelfke Dosimetric consequences of tumour motion due to respiration for a scanned proton beam Phys Med Biol 56 2011 6563 6581
9. Y. Kang, X. Zhang, and J.Y. Chang 4D Proton treatment planning strategy for mobile lung tumors Int J Radiat Oncol Biol Phys 67 2007 906 914
10. H.M. Kooy, B.M. Clasie, and H.-M. Lu A case study in proton pencil-beam scanning delivery Int J Radiat Oncol Biol Phys 76 2010 624 630
11. L.B. Marks, S.M. Bentzen, and J.O. Deasy Radiation dose-volume effects in the lung Int J Radiat Oncol Biol Phys 76 2010 S70 S76
12. E. Pedroni, D. Meer, and C. Bula Pencil beam characteristics of the next-generation proton scanning gantry of PSI: Design issues and initial commissioning results Eur Phys J Plus 126 2011 1 27
13. J. Perl, J. Shin, and J. Schümann TOPAS: An innovative proton Monte Carlo platform for research and clinical applications Med Phys 39 2012 6818 6837
14. K. Murphy, B. van Ginneken, and J.M. Reinhardt Evaluation of registration methods on thoracic CT: The EMPIRE10 challenge IEEE Trans Med Imaging 30 2011 1901 1920
15. J. Willner, K. Baier, and E. Caragiani Dose, volume, and tumor control prediction in primary radiotherapy of non-small-cell lung cancer Int J Radiat Oncol Biol Phys 52 2002 382 389