Preformulation study of methazolamide for topical ophthalmic delivery: Physicochemical properties and degradation kinetics in aqueous solutions

International Journal of Pharmaceutics

Volumn 448, Issue 2, 2013, Pages 390-393

  Jiang, Sunmin ^a   Wang, Fengzhen ^a   Zhu, Shuning ^a   Zhang, Xiumei ^a   Guo, Zhigang ^a   Li, Rui ^a   Xu, Qunwei ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Degradation; Methazolamide; Partition coefficient; Solubility; Stability

Indexed keywords

METHAZOLAMIDE; OCTANOL;

AQUEOUS SOLUTION; ARTICLE; CATALYSIS; DRUG DEGRADATION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; HYDROLYSIS; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TEMPERATURE;

ADMINISTRATION, OPHTHALMIC; CARBONIC ANHYDRASE INHIBITORS; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; DRUG STORAGE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; METHAZOLAMIDE; OPHTHALMIC SOLUTIONS; OSMOLAR CONCENTRATION; SOLUBILITY;

EID: 84877579093     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.03.018     Document Type: Article

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