Challenges with serum protein electrophoresis in assessing progression and clinical response in patients with waldenström macroglobulinemia

Clinical Lymphoma, Myeloma and Leukemia

Volumn 13, Issue 2, 2013, Pages 247-249

  Uljon, Sacha N ^a   Treon, Steven P ^b   Tripsas, Christina K ^b   Lindeman, Neal I ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN MU CHAIN; PARAPROTEIN; PLASMA PROTEIN;

CLINICAL EVALUATION; CLINICAL LABORATORY; CONFERENCE PAPER; CRYOGLOBULINEMIA; DISEASE COURSE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; NEPHELOMETRY; PROTEIN DETERMINATION; PROTEIN ELECTROPHORESIS; SPIKE; TREATMENT RESPONSE; TUMOR VOLUME; WALDENSTROEM MACROGLOBULINEMIA;

DISEASE PROGRESSION; ELECTROPHORESIS; HUMANS; IMMUNOGLOBULIN M; PARAPROTEINS; PROGNOSIS; PROTEIN MULTIMERIZATION; WALDENSTROM MACROGLOBULINEMIA;

EID: 84877346142     PISSN: 21522650     EISSN: 21522669     Source Type: Journal    
DOI: 10.1016/j.clml.2013.03.001     Document Type: Conference Paper

References (11)

1. R.G. Owen, R.A. Kyle, M.J. Stone Response assessment in Waldenstrom macroglobulinaemia: update from the VIth International Workshop Br J Haematol 160 2013 171 176
2. S.V. Rajkumar, J.L. Harousseau, B. Durie Consensus recommendations for the uniform reporting of clinical trials: report of the international myeloma workshop consensus Panel Blood 1 2011 117 4691-5
3. D.L. Murray, E. Ryu, M.R. Snyder Quantitation of serum monoclonal proteins: relationship between agarose gel electrophoresis and immunonephelometry Clin Chem 55 2009 1523 1529
4. C.K. Tripsas, C.J. Patterson, S. Uljon Comparative response assessment by serum IgM M-protein and total serum IgM following treatment of patients with Waldenström's macroglobulinemia Clin Lymphoma Myeloma Leuk 13 2013 250-2
5. A.R. Bradwell, H.D. Carr-Smith, G.P. Mead Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine Clin Chem 47 2001 673 680 (Pubitemid 32275810)
6. M. Drayson, L.X. Tang, R. Drew Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma Blood 97 2001 2900 2902
7. S. Mori, B.S. Crawford, J.V. Roddy Serum free light chains in myeloma patients with an intact M protein by immunofixation: potential roles for response assessment and prognosis during induction therapy with novel agents Hematol Oncol 30 2012 156 162
8. S.N. Uljon, P.G. Richardson, P.H. Schur Serial serum free light chain measurements do not detect changes in disease status earlier than electrophoretic M-spike measurements in patients with intact immunoglobulin myeloma Clin Chim Acta 412 2011 562 568
9. X. Leleu, E. Koulieris, D. Maltezas Novel M-component based biomarkers in Waldenstrom's macroglobulinemia Clin Lymphoma Myeloma Leuk 11 2011 164 167
10. R.J. Pattenden, K.L. Davidson, P.R. Wenham The value of serum free light chains in a case of Waldenstrom's macroglobulinaemia that produces a type I cryoglobulinaemia Ann Clin Biochem 46 2009 531 532
11. D.F. Keren, R. Gulbranson, J.L. Carey 2-mercaptoethanol treatment improves measurement of an IgMkappa M-protein by capillary electrophoresis Clin Chem 47 2001 1326 1327 (Pubitemid 32579130)