Cyclooxygenase-2 generates the endogenous mutagen trans-4-hydroxy-2-nonenal in Enterococcus faecalis-infected macrophages

Cancer Prevention Research

Volumn 6, Issue 3, 2013, Pages 206-216

  Wang, Xingmin ^a,b   Allen, Toby D ^a,b   Yang, Yonghong ^a,b   Moore, Danny R ^a,b   Huycke, Mark M ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; ALOX 5 PROTEIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLUTATHIONE; INTERLEUKIN 10; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE INHIBITOR; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CHEMICAL PARAMETERS; COLON BIOPSY; COMMENSALISM; CONTROLLED STUDY; DISEASE ASSOCIATION; ENTEROCOCCAL INFECTION; ENTEROCOCCUS FAECALIS; GENE SILENCING; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ADDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA; WESTERN BLOTTING;

ALDEHYDES; ANIMALS; BLOTTING, WESTERN; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; ENTEROCOCCUS FAECALIS; FLUORESCENT ANTIBODY TECHNIQUE; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84877308203     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-12-0350     Document Type: Article

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