Design and validation of bending test method for characterization of miniature pediatric cortical bone specimens

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

Volumn 227, Issue 2, 2013, Pages 105-113

  Albert, Carolyne I ^a,b   Jameson, John ^a   Harris, Gerald ^a,b  

^a Medical College of Wisconsin and Marquette University   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

Bone; Flexural; Material properties; Osteogenesis imperfecta; Pediatric

Indexed keywords

FLEXURAL; FLEXURAL PROPERTIES; LONGITUDINAL MODULUS; MATERIAL PROPERTY; MECHANICAL CHARACTERIZATIONS; OSTEOGENESIS IMPERFECTA; PATIENT POPULATION; THREE-POINT BENDING TEST; GENETIC DISORDERS;

ASPECT RATIO; BENDING STRENGTH; ELASTIC MODULI; MAMMALS; PEDIATRICS; TESTING; BONE; MATERIALS PROPERTIES; STEAM TURBINES;

BONE; STRENGTH OF MATERIALS;

ANIMAL; ARTICLE; BONE; CATTLE; CHILD; COMPRESSIVE STRENGTH; EQUIPMENT; FEMALE; HUMAN; MATERIALS TESTING; MECHANICAL STRESS; METHODOLOGY; OSTEOGENESIS IMPERFECTA; PATHOPHYSIOLOGY; PILOT STUDY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TENSILE STRENGTH; VALIDATION STUDY; YOUNG MODULUS;

ANIMALS; BONE AND BONES; CATTLE; CHILD; COMPRESSIVE STRENGTH; ELASTIC MODULUS; FEMALE; HUMANS; MATERIALS TESTING; OSTEOGENESIS IMPERFECTA; PILOT PROJECTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STRESS, MECHANICAL; TENSILE STRENGTH;

MLCS; MLOWN;

EID: 84877285682     PISSN: 09544119     EISSN: 20413033     Source Type: Journal    
DOI: 10.1177/0954411912463868     Document Type: Article

References (35)

1. Currey J. What determines the bending strength of compact bone? J Exp Biol 1999; 202: 2495-2503. (Pubitemid 29490142)
2. Draper ER and Goodship AE. A novel technique for four-point bending of small bone samples with semiautomatic analysis. J Biomech 2003; 36: 1497-1502. (Pubitemid 37117356)
3. Kemper N, Davison N, Fitzpatrick D, et al. Characterization of the mechanical properties of bovine cortical bone treated with a novel tissue sterilization process. Cell Tissue Bank 2010; 12: 273-279.
4. Reilly DT and Burstein AH. The elastic and ultimate properties of compact bone tissue. J Biomech 1975; 8: 393-405.
5. Zioupos P and Currey JD. Changes in the stiffness, strength, and toughness of human cortical bone with age. Bone 1998; 22: 57-66. (Pubitemid 28033654)
6. Currey JD and Butler G. The mechanical properties of bone tissue in children. J Bone Joint Surg Am1975; 57: 810-814.
7. Ohman C, Baleani M, Pani C, et al. Compressive behaviour of child and adult cortical bone. Bone 2011; 49: 769-776.
8. Fritz JM, Guan Y, Wang M, et al. A fracture risk assessment model of the femur in children with osteogenesis imperfecta (OI) during gait. Med Eng Phys 2009; 31: 1043-1048.
9. Fritz JM, Guan Y, Wang M, et al. Muscle force sensitivity of a finite element fracture risk assessment model in osteogenesis imperfecta - biomed 2009. Biomed Sci Instrum 2009; 45: 316-321.
10. Fan Z, Smith PA, Eckstein EC, et al. Mechanical properties of OI type III bone tissue measured by nanoindentation. J Biomed Mater Res A 2006; 79: 71-77. (Pubitemid 44452856)
11. Fan Z, Smith PA, Harris GF, et al. Comparison of nanoindentation measurements between osteogenesis imperfecta Type III and Type IV and between different anatomic locations (femur/tibia vs. iliac crest). Connect Tissue Res 2007; 48: 70-75. (Pubitemid 46680958)
12. Fan Z, Smith PA, Rauch F, et al. Nanoindentation as a means for distinguishing clinical type of osteogenesis imperfecta. Compos Part B: Eng 2007; 38: 411-415. (Pubitemid 46149465)
13. Weber M, Roschger P, Fratzl-Zelman N, et al. Pamidronate does not adversely affect bone intrinsic material properties in children with osteogenesis imperfecta. Bone 2006; 39: 616-622. (Pubitemid 44164641)
14. Kuhn JL, Goldstein SA, Choi K, et al. Comparison of the trabecular and cortical tissue moduli from human iliac crests. J Orthop Res 1989; 7: 876-884. (Pubitemid 19271861)
15. Choi K and Goldstein SA. A comparison of the fatigue behavior of human trabecular and cortical bone tissue. J Biomech 1992; 25: 1371-1381.
16. Choi K, Kuhn JL, Ciarelli MJ, et al. The elastic moduli of human subchondral, trabecular, and cortical bone tissue and the size-dependency of cortical bone modulus. J Biomech 1990; 23: 1103-1113.
17. Guo XE and Goldstein SA. Vertebral trabecular bone microscopic tissue elastic modulus and hardness do not change in ovariectomized rats. J Orthop Res 2000; 18: 333-336. (Pubitemid 30304765)
18. Albert C, Jameson J, Toth J, et al. Intrinsic modulus of bone in osteogenesis imperfecta - a nanoindentation study. In: 17th Biennial Canadian Society for Biomechanics Conference, CSB-SCB 2012 Presentations Program, Simon Fraser University website (http://ocs.sfu.ca/csb-scb/index.php/csb-scb/2012), Burnaby, BC, Canada, June 6-9, 2012.
19. Hoffler CE, Guo XE, Zysset PK, et al. An application of nanoindentation technique to measure bone tissue lamellae properties. J Biomech Eng 2005; 127: 1046-1053. (Pubitemid 43067259)
20. Rho JY and Pharr GM. Effects of drying on the mechanical properties of bovine femur measured by nanoindentation. J Mater Sci Mater Med 1999; 10: 485-488. (Pubitemid 29401641)
21. Rho JY, Zioupos P, Currey JD, et al. Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation. J Biomech 2002; 35: 189-198. (Pubitemid 34037094)
22. Currey JD. Mechanical properties of vertebrate hard tissues. Proc IMechE, Part H: J Engineering in Medicine 1998; 212: 399-411. (Pubitemid 128775831)
23. Wang X, Bank RA, TeKoppele JM, et al. The role of collagen in determining bone mechanical properties. J Orthop Res 2001; 19: 1021-1026. (Pubitemid 33150177)
24. Nyman JS, Roy A, Shen X, et al. The influence of water removal on the strength and toughness of cortical bone. J Biomech 2006; 39: 931-938. (Pubitemid 43243781)
25. Martin RB and Boardman DL. The effects of collagen fiber orientation, porosity, density, and mineralization on bovine cortical bone bending properties. J Biomech 1993; 26: 1047-1054. (Pubitemid 23235562)
26. Burstein AH, Currey JD, Frankel VH, et al. The ultimate properties of bone tissue: the effects of yielding. J Biomech 1972; 5: 35-44.
27. Currey J. Bones: structure and mechanics. 2nd ed. Princeton, NJ: Princeton University Press, 2002.
28. ASTM-D790-07. Standard methods for flexural properties of unreinforced and reinforced plastics and electrical insulating materials. West Conshohocken, PA: ASTM International, 2006.
29. Young WC and Budynas RG. Roark's formulas for stress and strain. 7th ed. McGraw-Hill, New York, NY, 2002.
30. ASTM-C674-88. Standard test methods for flexural properties of ceramic whiteware materials. West Conshohocken, PA: ASTM International, 2006.
31. Spatz HC, O'Leary EJ and Vincent JF. Young's moduli and shear moduli in cortical bone. Proc Biol Sci 1996; 263: 287-294. (Pubitemid 26100975)
32. Schriefer JL, Robling AG, Warden SJ, et al. A comparison of mechanical properties derived from multiple skeletal sites in mice. J Biomech 2005; 38: 467-475. (Pubitemid 40126457)
33. McCrum NG, Buckley CP and Bucknall CB. Principles of polymer engineering. 2nd ed. Oxford University Press, New York, NY, 1997.
34. Turner CH and Burr DB. Basic biomechanical measurements of bone: a tutorial. Bone 1993; 14: 595-608. (Pubitemid 23198821)
35. Rauch F, Travers R, Parfitt AM, et al. Static and dynamic bone histomorphometry in children with osteogenesis imperfecta. Bone 2000; 26: 581-589. (Pubitemid 30301650)