Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response.

Molecular medicine (Cambridge, Mass.)

Volumn 18, Issue , 2012, Pages 1346-1355

  Spruss, Astrid ^a   Henkel, Janin ^b   Kanuri, Giridhar ^b   Blank, Daniela ^b   Püschel, Gerhard P ^b   Bischoff, Stephan C ^b   Bergheim, Ina ^b  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; 4-HYDROXY-2-NONENAL; ADIPONECTIN; ADIPONECTIN RECEPTOR; ALDEHYDE; ENDOTOXIN; FRUCTOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; ISOMERASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROSTAGLANDIN E SYNTHASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CALORIC INTAKE; DISEASE PREDISPOSITION; ENZYMOLOGY; FATTY LIVER; FEMALE; HUMAN; INFLAMMATION; LIPID METABOLISM; LIVER; MALE; METABOLISM; MOUSE; NONALCOHOLIC FATTY LIVER; PATHOLOGY; PHOSPHORYLATION; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ADIPONECTIN; ALDEHYDES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DISEASE SUSCEPTIBILITY; ENDOTOXINS; ENERGY INTAKE; FATTY LIVER; FEMALE; FRUCTOSE; HUMANS; INFLAMMATION; INSULIN; INTRAMOLECULAR OXIDOREDUCTASES; LIPID METABOLISM; LIVER; MALE; MICE; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, ADIPONECTIN; SEX CHARACTERISTICS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; WEIGHT GAIN;

MLCS; MLOWN;

EID: 84877264082     PISSN: None     EISSN: 15283658     Source Type: Journal    
DOI: 10.2119/molmed.2012.00223     Document Type: Article

References (0)