Is pre-pregnancy weight a risk factor for intellectual disability?

Expert Review of Obstetrics and Gynecology

Volumn 8, Issue 3, 2013, Pages 197-199

  Mann, Joshua R ^a   Deroche, Chelsea B ^b   Spiryda, Lisa B ^a   McDermott, Suzanne ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

intellectual disability; obesity; pregnancy

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6;

ADVERSE OUTCOME; AUTISM; BODY MASS; DEVELOPMENTAL DISORDER; EPIDEMIC; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INTELLECTUAL IMPAIRMENT; MACROSOMIA; MATERNAL OBESITY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OBESITY; PREVALENCE; REVIEW; WEIGHT GAIN;

EID: 84877257796     PISSN: 17474108     EISSN: 17474116     Source Type: Journal    
DOI: 10.1586/eog.13.10     Document Type: Review

References (23)

1. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of Obesity in the United States, 2009-2010. NCHS Data Brief, No 82. National Center for Health Statistics, MD, USA (2012).
2. Institute of Medicine (US) and National Research Council (US) Committee to Reexamine IOM Pregnancy Weight Guidelines; Rasmussen KM, Yaktine AL. Weight Gain During Pregnancy: Reexamining the Guidelines. National Academies Press, Washington, DC, USA (2009).
3. Galtier-Dereure F, Boegner C, Bringer J. Obesity and pregnancy: complications and cost. Am. J. Clin. Nutr. 71, 1242S-1248S (2000).
4. Hedderson MM, Weiss NS, Sacks DA et al. Pregnancy weight gain and risk of neonatal complications: macrosomia, hypoglycemia, and hyperbilirubinemia. Obstet. Gynecol. 108(5), 1153-1161 (2006).
5. Blomberg MI, Källén B. Maternal obesity and morbid obesity: the risk for birth defects in the offspring. Birth Defects Res. Part A Clin. Mol. Teratol. 88(1), 35-40 (2010).
6. Dodds L, Fell DB, Shea S, Armson BA, Allen AC, Bryson S. The role of prenatal, obstetric and neonatal factors in the development of autism. J. Autism Dev. Disord. 41(7), 891-902 (2011).
7. Heikura U, Taanila A, Hartikainen AL et al. Variations in prenatal sociodemographic factors associated with intellectual disability: a study of the 20-year interval between two birth cohorts in northern Finland. Am. J. Epidemiol. 167(2), 169-177 (2008).
8. Neggers YH, Goldenberg RL, Ramey SL, Cliver SP. Maternal prepregnancy body mass index and psychomotor development in children. Acta Obstet. Gynecol. Scand. 82(3), 235-240 (2003).
9. Krakowiak P, Walker CK, Bremer AA et al. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics 129(5), e1121-e1128 (2012).
10. Brion MJ, Zeegers M, Jaddoe V et al. Intrauterine effects of maternal prepregnancy overweight on child cognition and behavior in 2 cohorts. Pediatrics 127(1), e202-e211 (2011).
11. Mann JR, McDermott SW, Hardin J, Pan C, Zhang Z. Pre-pregnancy body mass index, weight change during pregnancy, and risk of intellectual disability in children. BJOG 120(3), 309-319 (2013).
12. Power ML, Schulkin J. Maternal obesity, metabolic disease, and allostatic load. Physiol. Behav. 106(1), 22-28 (2012).
13. Basu S, Haghiac M, Surace P et al. Pregravid obesity associates with increased maternal endotoxemia and metabolic inflammation. Obesity (Silver Spring) 19(3), 476-482 (2011).
14. Challier JC, Basu S, Bintein T et al. Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta. Placenta 29(3), 274-281 (2008).
15. Leibowitz KL, Moore RH, Ahima RS et al. Maternal obesity associated with inflammation in their children. World J. Pediatr. 8(1), 76-79 (2012).
16. Huleihel M, Golan H, Hallak M. Intrauterine infection/inflammation during pregnancy and offspring brain damages: possible mechanisms involved. Reprod. Biol. Endocrinol. 2, 17 (2004).
17. Luzzo KM, Wang Q, Purcell SH et al. High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects. PLoS ONE 7(11), e49217 (2012).
18. Stachowiak EK, Oommen S, Vasu VT et al. Maternal obesity affects gene expression and cellular development in fetal brains. Nutr. Neurosci. doi:10.1071/RD12037 (2012) (Epub ahead of print).
19. Cerf ME, Williams K, van Rooyen J, Esterhuyse AJ, Muller CJ, Louw J. Gestational 30% and 40% fat diets increase brain GLUT2 and neuropeptide Y immunoreactivity in neonatal Wistar rats. Int. J. Dev. Neurosci. 28(7), 625-630 (2010).
20. Sullivan EL, Grayson B, Takahashi D et al. Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring. J. Neurosci. 30(10), 3826-3830 (2010).
21. Niculescu MD, Lupu DS. High fat diet-induced maternal obesity alters fetal hippocampal development. Int. J. Dev. Neurosci. 27(7), 627-633 (2009).
22. Jonakait GM. The effects of maternal inflammation on neuronal development: possible mechanisms. Int. J. Dev. Neurosci. 25(7), 415-425 (2007).
23. Tozuka Y, Kumon M, Wada E, Onodera M, Mochizuki H, Wada K. Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring. Neurochem. Int. 57(3), 235-247 (2010).