Prolactin Expression in the Cochlea of Aged BALB/c Mice Is Gender Biased and Correlates to Loss of Bone Mineral Density and Hearing Loss

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Marano, Robert J ^a,b   Tickner, Jennifer ^b   Redmond, Sharon L ^a,b  

^a EAR SCIENCE INSTITUTE AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CALCITONIN A; GROWTH HORMONE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROLACTIN; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE EXAMINATION; COCHLEA; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENDER BIAS; GENE EXPRESSION; HEARING IMPAIRMENT; HEARING TEST; HISTOPATHOLOGY; HORMONE DETERMINATION; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSTEOLYSIS; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

ACID PHOSPHATASE; AGING; ANIMALS; AUDITORY THRESHOLD; BONE AND BONES; BONE DENSITY; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; GENE EXPRESSION REGULATION; HEARING LOSS; ISOENZYMES; MALE; MICE; MICE, INBRED BALB C; OSTEOPROTEGERIN; PROLACTIN; RANK LIGAND; SEX CHARACTERISTICS;

EID: 84877153087     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063952     Document Type: Article

References (38)

1. Riddle O, Bates RW, Dykshorn SW, (1933) The preparation, identification and assay of prolactin - a hormone of the anterior pituitary. American Journal of Physiology 105: 191-216.
2. Ben-Jonathan N, Mershon JL, Allen DL, Steinmetz RW, (1996) Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. Endocr Rev 17: 639-669.
3. Ben-Jonathan N, LaPensee CR, LaPensee EW, (2008) What can we learn from rodents about prolactin in humans? Endocr Rev 29: 1-41.
4. Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA, (1998) Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19: 225-268.
5. Brandebourg T, Hugo E, Ben-Jonathan N, (2007) Adipocyte prolactin: regulation of release and putative functions. Diabetes Obes Metab 9: 464-476.
6. Egli M, Leeners B, Kruger TH, (2010) Prolactin secretion patterns: basic mechanisms and clinical implications for reproduction. Reproduction 140: 643-654.
7. Freeman ME, Kanyicska B, Lerant A, Nagy G, (2000) Prolactin: structure, function, and regulation of secretion. Physiol Rev 80: 1523-1631.
8. Emanuele NV, Jurgens JK, Halloran MM, Tentler JJ, Lawrence AM, et al. (1992) The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA. Mol Endocrinol 6: 35-42.
9. Ramesh R, Kuenzel WJ, Buntin JD, Proudman JA, (2000) Identification of growth-hormone- and prolactin-containing neurons within the avian brain. Cell Tissue Res 299: 371-383.
10. Roselli CE, Bocklandt S, Stadelman HL, Wadsworth T, Vilain E, et al. (2008) Prolactin expression in the sheep brain. Neuroendocrinology 87: 206-215.
11. Torner L, Maloumby R, Nava G, Aranda J, Clapp C, et al. (2004) In vivo release and gene upregulation of brain prolactin in response to physiological stimuli. Eur J Neurosci 19: 1601-1608.
12. Charoenphandhu N, Teerapornpuntakit J, Methawasin M, Wongdee K, Thongchote K, et al. (2008) Prolactin decreases expression of Runx2, osteoprotegerin, and RANKL in primary osteoblasts derived from tibiae of adult female rats. Can J Physiol Pharmacol 86: 240-248.
13. Seriwatanachai D, Thongchote K, Charoenphandhu N, Pandaranandaka J, Tudpor K, et al. (2008) Prolactin directly enhances bone turnover by raising osteoblast-expressed receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio. Bone 42: 535-546.
14. Horner KC, Cazals Y, Guieu R, Lenoir M, Sauze N, (2007) Experimental estrogen-induced hyperprolactinemia results in bone-related hearing loss in the guinea pig. Am J Physiol Endocrinol Metab 293: E1224-32.
15. Marano RJ, Tickner J, Redmond SL, (2012) Age related changes in gene expression within the cochlea of C57BL/6J mice. Aging Clin Exp Res 24: 603-611.
16. Carpinelli MR, Wise AK, Burt RA, (2011) Vitamin D-deficient diet rescues hearing loss in Klotho mice. Hear Res 275: 105-109.
17. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
18. Willott JF, Turner JG, Carlson S, Ding D, Seegers Bross L, et al. (1998) The BALB/c mouse as an animal model for progressive sensorineural hearing loss. Hear Res 115: 162-174.
19. Ohlemiller KK, (2009) Mechanisms and genes in human strial presbycusis from animal models. Brain Res 1277: 70-83.
20. Johnson KR, Erway LC, Cook SA, Willott JF, Zheng QY, (1997) A major gene affecting age-related hearing loss in C57BL/6J mice. Hear Res 114: 83-92.
21. Johnson KR, Zheng QY, Erway LC, (2000) A major gene affecting age-related hearing loss is common to at least ten inbred strains of mice. Genomics 70: 171-180.
22. Liu XZ, Yan D, (2007) Ageing and hearing loss. J Pathol 211: 188-197.
23. Fetoni AR, Picciotti PM, Paludetti G, Troiani D, (2011) Pathogenesis of presbycusis in animal models: a review. Exp Gerontol 46: 413-425.
24. Colao A, Di Somma C, Loche S, Di Sarno A, Klain M, et al. (2000) Prolactinomas in adolescents: persistent bone loss after 2 years of prolactin normalization. Clin Endocrinol (Oxf) 52: 319-327.
25. Meaney AM, O'Keane V, (2003) Reduced bone mineral density in patients with schizophrenia receiving prolactin raising anti-psychotic medication. J Psychopharmacol 17: 455-458.
26. Seriwatanachai D, Charoenphandhu N, Suthiphongchai T, Krishnamra N, (2008) Prolactin decreases the expression ratio of receptor activator of nuclear factor kappaB ligand/osteoprotegerin in human fetal osteoblast cells. Cell Biol Int 32: 1126-1135.
27. Berwaer M, Martial JA, Davis JR, (1994) Characterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene. Mol Endocrinol 8: 635-642.
28. Nelson EG, Hinojosa R, (2006) Presbycusis: a human temporal bone study of individuals with downward sloping audiometric patterns of hearing loss and review of the literature. Laryngoscope 116: 1-12.
29. Sharashenidze N, Schacht J, Kevanishvili Z (2007) Age-related hearing loss: gender differences. Georgian Med News 14-18.
30. Abraham G, Paing WW, Kaminski J, Joseph A, Kohegyi E, et al. (2003) Effects of elevated serum prolactin on bone mineral density and bone metabolism in female patients with schizophrenia: a prospective study. Am J Psychiatry 160: 1618-1620.
31. Misra M, Papakostas GI, Klibanski A (2004) Effects of psychiatric disorders and psychotropic medications on prolactin and bone metabolism. J Clin Psychiatry 65: 1607-18; quiz 1590, 1760-1.
32. Stenberg AE, Wang H, Fish Jr, Schrott-Fischer A, Sahlin L, et al. (2001) Estrogen receptors in the normal adult and developing human inner ear and in Turner's syndrome. Hear Res 157: 87-92.
33. Simonoska R, Stenberg AE, Duan M, Yakimchuk K, Fridberger A, et al. (2009) Inner ear pathology and loss of hearing in estrogen receptor-beta deficient mice. J Endocrinol 201: 397-406.
34. Adamson AD, Friedrichsen S, Semprini S, Harper CV, Mullins JJ, et al. (2008) Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling. Endocrinology 149: 687-694.
35. Duan R, Ginsburg E, Vonderhaar BK, (2008) Estrogen stimulates transcription from the human prolactin distal promoter through AP1 and estrogen responsive elements in T47D human breast cancer cells. Mol Cell Endocrinol 281: 9-18.
36. Horiguchi K, Naito J, Ishida M, Harigaya T, (2007) The effect of estrogen on phosphorylation of prolactin in the mouse pituitary gland. J Reprod Dev 53: 515-523.
37. Atkins GJ, Findlay DM, (2012) Osteocyte regulation of bone mineral: a little give and take. Osteoporos Int 23: 2067-2079.
38. Qing H, Bonewald LF, (2009) Osteocyte remodeling of the perilacunar and pericanalicular matrix. Int J Oral Sci 1: 59-65.