Medication complexity, prescription behaviour and patient adherence at the interface between ambulatory and stationary medical care

European Journal of Clinical Pharmacology

Volumn 69, Issue 3, 2013, Pages 573-580

  Stange, Dorit ^a   Kriston, Levente ^a   Von Wolff, Alessa ^a   Baehr, Michael ^a   Dartsch, Dorothee C ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Adherence; Ambulatory stationary interface; Complexity; Continuity of patient care; Hospitalization

Indexed keywords

ADULT; AGED; AMBULATORY CARE; ARTICLE; CLINICAL PRACTICE; CONTROLLED STUDY; FEMALE; GENERAL PRACTITIONER; HEALTH PERSONNEL ATTITUDE; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; INTERNAL MEDICINE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEDICATION THERAPY MANAGEMENT; OBSERVATIONAL STUDY; PATIENT ATTITUDE; PATIENT COMPLIANCE; PATIENT TRANSPORT; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUESTIONNAIRE; SCORING SYSTEM; UROLOGY;

ADULT; AGED; AGED, 80 AND OVER; AMBULATORY CARE; ATTITUDE OF HEALTH PERSONNEL; BUDGETS; CHI-SQUARE DISTRIBUTION; CONTINUITY OF PATIENT CARE; DRUG COSTS; DRUG PRESCRIPTIONS; FEMALE; GENERAL PRACTITIONERS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT ADMISSION; PATIENT DISCHARGE; PHYSICIAN'S PRACTICE PATTERNS; POLYPHARMACY; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 84877111699     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1342-2     Document Type: Article

References (37)

1. Gray SL, Mahoney JE, Blough DK (2001) Medication adherence in elderly patients receiving home health services following hospital discharge. Ann Pharmacother 35:539-545
2. Col N, Fanale JE, Kronholm P (1990) The role of medication noncompliance and adverse drug reactions in hospitalizations of the elderly. Arch Intern Med 150:841-845
3. Osterberg L, Blaschke T (2005) Adherence to medication. N Engl J Med 353:487-497
4. De Geest S, Sabate E (2003) Adherence to long-term therapies: evidence for action. Eur J Cardiovasc Nurs 2:323
5. Stephenson J (1999) Noncompliance may cause half of antihypertensive drug "failures". JAMA 282:313-314
6. Sokol MC, McGuigan KA, Verbrugge RR, Epstein RS (2005) Impact of medication adherence on hospitalization risk and healthcare cost. Med Care 43:521-530
7. Vlasnik JJ, Aliotta SL, DeLor B (2005) Medication adherence: factors influencing compliance with prescribed medication plans. Case Manager 16:47-51
8. Beers MH, Dang J, Hasegawa J, Tamai IY (1989) Influence of hospitalization on drug therapy in the elderly. J Am Geriatr Soc 37:679-683
9. Himmel W, Kochen MM, Sorns U, Hummers-Pradier E (2004) Drug changes at the interface between primary and secondary care. Int J Clin Pharmacol Ther 42:103-109
10. Schnurrer JU, Stichtenoth DO, Troost R, Frolich JC (2001) Drug expenditure in hospitals: what do German ward physicians know? Br J Clin Pharmacol 51:342-344
11. Mant A, Rotem WC, Kehoe L, Kaye KI (2001) Compliance with guidelines for continuity of care in therapeutics from hospital to community. Med J Aust 174:277-280
12. Williams EI, Fitton F (1990) General practitioner response to elderly patients discharged from hospital. Br Med J 300:159-161
13. Claxton AJ, Cramer J, Pierce C (2001) A systematic review of the associations between dose regimens and medication compliance. Clin Ther 23:1296-1310
14. Kripalani S, Yao X, Haynes RB (2007) Interventions to enhance medication adherence in chronic medical conditions: a systematic review. Arch Intern Med 167:540-550
15. Bangalore S, Kamalakkannan G, Parkar S, Messerli FH (2007) Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 120:713-719
16. Choudhry NK, Fischer MA, Avorn J, et al (2011) The implications of therapeutic complexity on adherence to cardiovascular medications. Arch Intern Med. 171:814-822
17. Mansur N, Weiss A, Hoffman A, Gruenewald T, Beloosesky Y (2008) Continuity and adherence to long-term drug treatment by geriatric patients after hospital discharge: a prospective cohort study. Drugs Aging 25:861-870
18. Mahler C, Hermann K, Horne R, et al (2010) Assessing reported adherence to pharmacological treatment recommendations. Translation and evaluation of the Medication Adherence Report Scale (MARS) in Germany. J Eval Clin Pract 16:574-579
19. Horne R, Weinman J (1999) Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 47:555-567
20. George J, Kong DC, Thoman R, Stewart K (2005) Factors associated with medication nonadherence in patients with COPD. Chest 128:3198-3204
21. Stange D, Kriston L, Langebrake C, et al (2012) Development and psychometric evaluation of the German version of the Medication Regimen Complexity Index (MRCI-D). J Eval Clin Pract 18(3):515-522
22. George J, Phun YT, Bailey MJ, Kong DC, Stewart K (2004) Development and validation of the medication regimen complexity index. Ann Pharmacother 38:1369-1376
23. Correr CJ, Melchiors AC, Fernandez-Llimos F, Pontarolo R (2011) Effects of a pharmacotherapy follow-up in community pharmacies on type 2 diabetes patients in Brazil. Int J Clin Pharm 33(2):273-280
24. Melchiors AC, Correr CJ, Fernandez-Llimos F (2007) Translation and validation into Portuguese language of the medication regimen complexity index. Arq Bras Cardiol 89:210-218
25. Cardone KE, Manley HJ, Grabe DW, Meola S, Hoy CD, Bailie GR (2011) Quantifying home medication regimen changes and quality of life in patients receiving nocturnal home hemodialysis. Hemodial Int 15:234-242
26. Himmel W, Tabache M, Kochen MM (1996) What happens to long-term medication when general practice patients are referred to hospital? Eur J Clin Pharmacol 50:253-257
27. Unroe KT, Pfeiffenberger T, Riegelhaupt S, Jastrzembski J, Lokhnygina Y, Colon-Emeric C (2010) Inpatient medication reconciliation at admission and discharge: A retrospective cohort study of age and other risk factors for medication discrepancies. Am J Geriatr Pharmacother 8:115-126
28. van Eijken M, Tsang S, Wensing M, de Smet PA, Grol RP (2003) Interventions to improve medication compliance in older patients living in the community: a systematic review of the literature. Drugs Aging 20:229-240
29. Elzubier AG, Husain AA, Suleiman IA, Hamid ZA (2000) Drug compliance among hypertensive patients in Kassala, eastern Sudan. East Mediterr Health J 6:100-105
30. Vrijens B, Vincze G, Kristanto P, Urquhart J, Burnier M (2008) Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories. Br Med J 336:1114-1117
31. Garber MC, Nau DP, Erickson SR, Aikens JE, Lawrence JB (2004) The concordance of self-report with other measures of medication adherence: a summary of the literature. Med Care 42:649-652
32. van de Steeg N, Sielk M, Pentzek M, Bakx C, Altiner A (2009) Drug-adherence questionnaires not valid for patients taking blood-pressure- lowering drugs in a primary health care setting. J Eval Clin Pract 15:468-472
33. Nieuwenhuis MM, Jaarsma T, van Veldhuisen DJ, van der Wal MH (2012) Self-reported versus 'true' adherence in heart failure patients: a study using the Medication Event Monitoring System. Neth Heart J [Epub ahead of print]
34. Cook CL, Wade WE, Martin BC, Perri M 3rd (2005) Concordance among three self-reported measures of medication adherence and pharmacy refill records. J Am Pharmacists Assoc 45:151-159
35. Haynes RB, Taylor DW, Sackett DL, Gibson ES, Bernholz CD, Mukherjee J (1980) Can simple clinical measurements detect patient noncompliance? Hypertension 2:757-764
36. Webb DG, Horne R, Pinching AJ (2001) Treatment-related empowerment: preliminary evaluation of a new measure in patients with advanced HIV disease. Int J STD AIDS 12:103-107
37. Foddy W (1993) Constructing questions for interviews and questionnaires: theory and practice in social research. Cambridge University Press, Cambridge