Differential Expression Profiles in the Midgut of Triatoma infestans Infected with Trypanosoma cruzi

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Buarque, Diego S ^a   Braz, Glória R C ^b   Martins, Rafael M ^c   Tanaka Azevedo, Anita M ^d   Gomes, Cícera M ^d   Oliveira, Felipe A A ^a   Schenkman, Sergio ^a   Tanaka, Aparecida S ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c INSTITUT PASTEUR   (France)

^d INSTITUTO BUTANTAN   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; DEFENSIN; HORMONE BINDING PROTEIN; JUVENILE HORMONE BINDING PROTEIN; LIPOCALIN; LYSOZYME; RNA; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; GENETIC TRANSCRIPTION; MIDGUT; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE VECTOR; TRIATOMA INFESTANS; TRYPANOSOMA CRUZI; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; GENE EXPRESSION PROFILING; HOST-PARASITE INTERACTIONS; INTESTINES; RNA, MESSENGER; TRIATOMA; TRYPANOSOMA CRUZI; UP-REGULATION;

HEXAPODA; PROTOZOA; TRIATOMA INFESTANS; TRIATOMINAE; TRYPANOSOMA CRUZI;

EID: 84877071530     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061203     Document Type: Article

References (51)

1. Ursic-Bedoya R, Buchhop J, Joy JB, Durvasula R, Lowenberger C, (2011) Prolixicin: a novel antimicrobial peptide isolated from Rhodnius prolixus with differential activity against bacteria and Trypanosoma cruzi. Insect Mol Biol 20 (6) (): 775-786.
2. Bussacos ACM, Nakayasu ES, Hecht MM, Assumpção TCF, Parente JA, et al. (2011) Redundancy of proteins in salivary glands of Panstrongylus megistus secures prolonged procurement for blood meal. J proteom 74: 1693-1700.
3. Rassi A Jr, Rassi A, Marin-Neto JA, (2010) Chagas disease. Lancet 375: 1388-1402.
4. Ursic-Bedoya RJ, Lowenberger CA, (2007) Rhodnius prolixus: Identification of immune-related genes up-regulated in response to pathogens and parasites using suppressive subtractive hybridization. Dev Comp Immunol 31: 109-120.
5. Mesquita RD, Carneiro AB, Bafica A, Gazos-Lopes L, Takiya CM, et al. (2008) Trypanosoma cruzi infection is enhanced by vector saliva through immunosupressant mechanisms mediated by lysophosphatydilcholine. Infect Immun 76 (12) (): 5543-5552.
6. Kavanagh K, Reeves EP, (2007) Insect and mammalian innate immune responses are much alike. Microbe 2: 596-599.
7. Araujo CAC, Waniek PJ, Stock P, Mayer C, Jansen AM, et al. (2006) Sequence characterization and expression patterns of defensin and lysozyme encoding genes from the gut of the reduviid bug Triatoma brasiliensis. Insect Biochem Mol Biol 36: 547-560.
8. Ursic-Bedoya RJ, Nazzari H, Cooper D, Triana O, Wolff M, et al. (2008) Identification and characterization of two novel lysozymes from Rhodnius prolixus, a vector of Chagas disease. J insect Physiol 54: 593-603.
9. Waniek PJ, Jansen AM, Araújo CAC, (2011) Trypanosoma cruzi infection modulates the expression of Triatoma brasiliensis def1 in the midgut. Vec Born Zoonot Dis 11 (7) (): 845-847.
10. Whitten S, Sun F, Tew I, Schaub G, Soukou C, et al. (2007) Differential modulation of Rhodnius prolixus nitric oxide activity following challenge with Trypanosoma rangeli, T. cruzi and bacterial cell wall components. Insect Biochem Mol Biol 37 (5) (): 440-452.
11. Avila ML, Tekiel V, Moretti G, Nicosia S, Bua J, et al. (2011) Gene Discovery in Triatoma infestans. Parasit Vec 4: 39.
12. Lopez L, Morales G, Ursic R, Wolff M, Lowenberger CA, (2003) Isolation and characterization of a novel insect defensin from Rhodnius prolixus, a vector of Chagas disease. Insect Biochem Mol Biol 33: 439-447.
13. Santos A, Ribeiro JMC, Lehane MJ, Gontijo NF, Veloso AB, et al. (2007) The sialotranscriptome of the blood-sucking bug Triatoma brasiliensis (Hemiptera, Triatominae). Insect Biochem Mol Biol 37: 702-712.
14. Assumpção TCF, Francischetti IBM, Andersen JF Schwarz A, Santana JM, et al. (2008) An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease. Insect Biochem Mol Biol 38: 213-232.
15. Kato H, Jochim RC, Gomez EA, Sakoda R, Iwata H, et al. (2010) Repertoire of dominant transcripts from the salivary glands of the blood-sucking bug, Triatoma dimidiata, a vector of Chagas disease. Infect Genet Evol 10: 184-191.
16. Medeiros MN, Logullo R, Ramos IB, Sorgine MHF, Paiva-Silva GO, et al. (2011) Transcriptome and gene expression profile of ovarian follicule tissue of the triatomine bug Rhodnius prolixus. Insect Biochem Mol Biol 41: 823-831.
17. Etebari K, Palfreyman RW, Schlipalius D, Nielsen LK, Glatz RV, et al. (2011) Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum. BMC Genomics 12: 446.
18. Wommack KE, Bhavsar J, Ravel J, (2008) Metagenomics: read length matters. Appl Environ Microbiol 74 (5) (): 1453-1463.
19. International_Aphid_Genome_Consortium: Genome sequence of the pea aphid Acyrthosiphon pisum (2010) PLoS Biol 8: e1000313.
20. Graça-Souza AV, Maya Monteiro AV, Paiva-Silva GO, Braz GRC, Paes MC, et al. (2006) Adaptations against heme toxicity in blood-feeding athropods. Insect Biochem Mol Biol 36: 322-335.
21. Paes MC, Consentino-Gomes D, de Souza CV, Nogueira NP, Meyer-Fernandes JR, (2011) The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi. J Parasitol Res 174614.
22. Ascenzi P, Gradoni L, (2002) Nitric oxide limits parasite development in vectors and in invertebrate intermediate hosts. IBMB Life 53 (2) (): 121-123.
23. Piacenza L, Peluffo G, Alvarez MN, Martinez A, Radi R, (2012) Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease. Antioxid Redox Signal In press.
24. Kollien AH, Fechner S, Waniek PJ, Schaub GA, (2003) Isolation and characterization of a cDNA encoding for a lysozyme from the gut of the Reduviidae bug Triatoma infestans. Arch Insect Biochem Physiol 53 (3) (): 134-145.
25. Mello CB, Garcia ES, Ratcliffe NA, Azambuja P, (1995) Trypanosoma cruzi and Trypanosoma rangeli: interplay with hemolimph components of Rhodnius prolixus. J Invertebr Pathol 65 (3) (): 261-268.
26. Balczun C, Siemanowski J, Pausch JK, Helling S, Marcus K, et al. (2012) Intestinal aspartate proteases TiCatD and TiCatD2 of the haematophagous bug Triatoma infestans (Reduviidae): Sequence characterisation, expression pattern and characterisation of proteolytic activity. Insect Biochem Mol Biol 42 (4) (): 240-250.
27. Borges EC, Machado EMM, Garcia ES, Azambuja P, (2006) Trypanosoma cruzi: effects of infection in cathepsin D activity in the midgut of Rhodnius prolixus. Exp Parasitol 112: 110-133.
28. Turk V, Stoka V, Turk D, (2008) Cystatins: biochemical and structural properties, and medical relevance. Front Biosci 13: 5406-5420.
29. Buarque DS, Spindola LM, Martins RM, Braz GR, Tanaka AS, (2011) Tigutcystatin, a cysteine protease inhibitor from Triatoma infestans midgut expressed in response to Trypanosoma cruzi. Biochem Biophys Res Commun 413 (2) (): 241-247.
30. Scharfstein J, Lima APCA, (2008) Roles of Naturally Occurring Protease Inhibitors in the modulation of Host Cell Signaling and Cellular Invasion by Trypanosoma cruzi. Subcell Biochem 47: 140-154.
31. Campos IT, Amino R, Sampaio CA, Auerswald EA, Friedrich T, et al. (2002) Infestin, a thrombin inhibitor presents in Triatoma infestans midgut, a Chagas' disease vector: gene cloning, expression and characterization of the inhibitor. Insect Biochem Mol Biol 32: 991-997.
32. Campos IT, Tanaka-Azevedo AM, Tanaka AS, (2004) Identification and characterization of a novel fator XIIa inhibitor in the hematophagous insect Triatoma infestans (Hemiptera: Reduviidae). FEBS Lett 577 (3) (): 512-516.
33. Araujo RN, Campos ITN, Tanaka AS, Santos A, Gontijo NF, et al. (2007) Brasiliensin, A novel intestinal thrombin inhibitor from Triatoma brasiliensis (Hemiptera: Reduviidae) with an important role in blood intake. Int J Parasitol 37: 1351-1358.
34. Lovato DV, Amino R, Gonzalez Y, Miranda A, Schenkman S, et al. (2011) Infestin 1R, an intestinal subtilisin inhibitor from Triatoma infestans able to impair mammalian cell invasion by Trypanosoma cruzi. Exp Parasitol 129 (4) (): 362-367.
35. Flower DR, North AC, Sansom CE, (2000) The lipocalin protein family: structural and sequence overview. Biochim Biophys Acta 1482: 9-24.
36. Mans BJ, Ribeiro JMC, (2008) Function, mechanism and evolution of the moubatin-clade of soft tick lipocalins. Insect biochem Mol Biol 38: 841-852.
37. Fuentes-Prior P, Noeske-Jungblut C, Donner P, Schleuning WD, Huber R, et al. (1997) Structure of thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug. Proc Natl Acad Sci 94: 11845-11850.
38. Raj PA, Dentino AR, (2002) Current status of defensins and their role in innate and adaptive immunity. FEMS Microbiol Lett 206: 9-18.
39. Kollien AH, Schaub GA, (1998) Trypanosoma cruzi in the rectum of the bug Triatoma infestans: effects of blood ingestion by the starved vector. Am J Trop Med Hyg 59 (1) (): 166-170.
40. Sambrook J (1989) Molecular cloning: a laboratory manual, second ed. Edited by Fritsch F, Maniatis T.
41. Altschul SF, Gish W, (1996) Local alignment statistics. Methods Enzymol 266: 460-480.
42. Huang X, Madan A, (1999) CAP3: a DNA sequence assembly program. Gen Res 9: 868-877.
43. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acid Res 25: 3389-3402.
44. Guo Y, Ribeiro JM, Anderson JM, Bour S, (2009) dCAS: a desktop application for cDNA sequence annotation. Bioinf 25 (9) (): 1195-1196.
45. Marchler-Bauer A, Panchenko AR, Shoemaker BA, Thiessen PA, Geer LY, et al. (2002) CDD: a database of conserved domain alignments with links to domain three-dimensional structure. Nucleic Acid Res 30: 281-283.
46. Bateman A, Birney E, Durbin R, Eddy SR, Howe KL, et al. (2000) The Pfam protein families database. Nucleic Acids Res 28: 263-266.
47. Tatusov RL, Fedorova ND, Jackson JD, Jacobs AR, Kiryutin B, et al. (2003) The COG database: an updated version includes eukaryotes. BMC Bioinformatics 4: 41.
48. Letunic I, Goodstadt L, Dickens NJ, Doerks T, Schultz J, et al. (2002) Recent improvements to the SMART domain-based sequence annotation resource. Nucleic Acid Res 30: 242-244.
49. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
50. Blanco E, Parra G, Guigó R (2002) Using geneid to Identify Genes. In: Baxevanis, A. (Eds.), Current Protocols in Bioinformatics. Unit 4.3. John Wiley & Sons Inc., New York.
51. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real time quantitative PCR and the 2-[Delta][Delta]CT method. Methods 25: 402-408.