Validation of minor stroke definitions for thrombolysis decision making

Journal of Stroke and Cerebrovascular Diseases

Volumn 22, Issue 4, 2013, Pages 482-490

  Park, Tai Hwan ^a   Hong, Keun Sik ^b   Choi, Jay Chol ^c   Song, Pamela ^b   Lee, Ji Sung ^d   Lee, Juneyoung ^d   Park, Jong Moo ^e   Kang, Kyusik ^e   Lee, Kyung Bok ^f   Cho, Yong Jin ^b   Saposnik, Gustavo ^g   Han, Moon Ku ^h   Bae, Hee Joon ^h  

^a Seoul Medical Center   (South Korea)

^b Inje University College of Medicine   (South Korea)

^c Jeju National University College of Medicine   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e Eulji General Hospital   (South Korea)

^f Soonchunhyang University College of Medicine   (South Korea)

^g ST MICHAEL'S HOSPITAL   (Canada)

^h Seoul National University Bundang Hospital   (South Korea)

Author keywords

acute ischemic stroke; Minor stroke definition; NINDS TPA trials; outcome; thrombolysis

Indexed keywords

ADULT; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CONSCIOUSNESS; DISEASE CLASSIFICATION; DYSARTHRIA; FACIAL NERVE PARALYSIS; FEMALE; FIBRINOLYTIC THERAPY; GAZE; HUMAN; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; RANKIN SCALE; REFERENCE VALUE; SENSORY DYSFUNCTION; VALIDITY; CLASSIFICATION; CLINICAL TRIAL; COMPLICATION; DECISION SUPPORT SYSTEM; DISABILITY; MIDDLE AGED; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; NOMENCLATURE; PATIENT SELECTION; PREDICTIVE VALUE; REGISTER; REPRODUCIBILITY; RISK; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SOUTH KOREA; STATISTICAL MODEL; STROKE; VALIDATION STUDY;

AGED; DECISION SUPPORT TECHNIQUES; DISABILITY EVALUATION; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REGISTRIES; REPRODUCIBILITY OF RESULTS; REPUBLIC OF KOREA; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE; TERMINOLOGY AS TOPIC; THROMBOLYTIC THERAPY;

EID: 84877010650     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2013.03.006     Document Type: Article

References (22)

1. H.P. Adams Jr., G. del Zoppo, and M.J. Alberts Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists Stroke 38 2007 1655 1711
2. P.A. Barber, J. Zhang, and A.M. Demchuk Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility Neurology 56 2001 1015 1020
3. D. Kleindorfer, B. Kissela, and A. Schneider Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: a population-based study Stroke 35 2004 e27 e29
4. K. Nedeltchev, B. Schwegler, and T. Haefeli Outcome of stroke with mild or rapidly improving symptoms Stroke 38 2007 2531 2535
5. E.E. Smith, G.C. Fonarow, and M.J. Reeves Outcomes in mild or rapidly improving stroke not treated with intravenous recombinant tissue-type plasminogen activator: findings from Get With The Guidelines-Stroke Stroke 42 2011 3110 3115
6. W. Hacke, M. Kaste, and E. Bluhmki Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke N Engl J Med 359 2008 1317 1329
7. W.M. Clark, S. Wissman, and G.W. Albers Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke JAMA 282 1999 2019 2026
8. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group N Engl J Med 333 1995 1581 1587
9. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group Recombinant tissue plasminogen activator for minor strokes: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study experience Ann Emerg Med 46 2005 243 252
10. P. Khatri, D.O. Kleindorfer, and S.D. Yeatts Strokes with minor symptoms: an exploratory analysis of the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials Stroke 41 2010 2581 2586
11. H.P. Adams Jr., B.H. Bendixen, and L.J. Kappelle Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment Stroke 24 1993 35 41
12. A. Agresti, and B.A. Coull Approximate is better than exact for interval estimation of binomial proportions The American Statistician 52 1998 119 126
13. T.J. Ingall, W.M. O'Fallon, and K. Asplund Findings from the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial Stroke 35 2004 2418 2424
14. R.J. Dachs, J.H. Burton, and J. Joslin A user's guide to the NINDS rt-PA stroke trial database PLoS Med 5 2008 e113
15. P. Khatri, M.R. Conaway, and K.C. Johnston Ninety-day outcome rates of a prospective cohort of consecutive patients with mild ischemic stroke Stroke 43 2012 560 562
16. M. Kohrmann, T. Nowe, and H.B. Huttner Safety and outcome after thrombolysis in stroke patients with mild symptoms Cerebrovasc Dis 27 2009 160 166
17. E.C. Leira, B.R. Ludwig, and M.E. Gurol The types of neurological deficits might not justify withholding treatment in patients with low total National Institutes of Health Stroke Scale scores Stroke 43 2012 782 786
18. E.E. Smith, A.R. Abdullah, and I. Petkovska Poor outcomes in patients who do not receive intravenous tissue plasminogen activator because of mild or improving ischemic stroke Stroke 36 2005 2497 2499
19. V. Rajajee, C. Kidwell, and S. Starkman Early MRI and outcomes of untreated patients with mild or improving ischemic stroke Neurology 67 2006 980 984
20. M.S. Dhamoon, Y.P. Moon, and M.C. Paik Long-term functional recovery after first ischemic stroke: the Northern Manhattan Study Stroke 40 2009 2805 2811
21. D. Kleindorfer, J. Broderick, and J. Khoury The unchanging incidence and case-fatality of stroke in the 1990s: a population-based study Stroke 37 2006 2473 2478
22. K.H. Jung, S.H. Lee, and B.J. Kim Secular trends in ischemic stroke characteristics in a rapidly developed country: results from the Korean Stroke Registry Study (Secular Trends in Korean Stroke) Circ Cardiovasc Qual Outcomes 5 2012 327 334