Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Ohishi, Jun ^a   Aoki, Mikiko ^a   Nabeshima, Kazuki ^a   Suzumiya, Junji ^b   Takeuchi, Tamotsu ^c   Ogose, Akira ^d   Hakozaki, Michiyuki ^e   Yamashita, Yuichi ^a   Iwasaki, Hiroshi ^a  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHIMANE UNIVERSITY HOSPITAL   (Japan)

^c Giju University School of Medicine   (Japan)

^d NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^e FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMATINIB; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CHROMOSOME REARRANGEMENT; COLONY FORMATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; MOUSE; NONHUMAN; PLATELET DERIVED GROWTH FACTOR B GENE; PLATELET DERIVED GROWTH FACTOR RECEPTOR BETA GENE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TUMOR XENOGRAFT;

ANIMALS; BENZAMIDES; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; MUTATION; NEOPLASTIC STEM CELLS; NERVE SHEATH NEOPLASMS; PHOSPHORYLATION; PIPERAZINES; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER;

EID: 84876974448     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-224     Document Type: Article

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