Enterococcus faecalis infective endocarditis a pilot study of the relationship between duration of gentamicin treatment and outcome

Circulation

Volumn 127, Issue 17, 2013, Pages 1810-1817

  Dahl, Anders ^a   Rasmussen, Rasmus V ^a   Bundgaard, Henning ^a   Hassager, Christian ^a   Bruun, Louise E ^a   Lauridsen, Trine K ^a   Moser, Claus ^a   Sogaard, Peter ^a   Arpi, Magnus ^a   Bruun, Niels E ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Endocarditis; Enterococcus; Gentamicins; Kidney; Mortality

Indexed keywords

GENTAMICIN;

AGED; ARTICLE; BACTERIAL ENDOCARDITIS; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; CREATININE CLEARANCE; DISEASE PREDISPOSITION; ENTEROCOCCUS FAECALIS; EVENT FREE SURVIVAL; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEART FAILURE; HOSPITALIZATION; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; NONHUMAN; PILOT STUDY; PRIORITY JOURNAL; PROSTHETIC VALVE ENDOCARDITIS; RELAPSE; SURVIVAL RATE; TREATMENT DURATION; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; COHORT STUDIES; DENMARK; ENDOCARDITIS, BACTERIAL; ENTEROCOCCUS FAECALIS; FEMALE; FOLLOW-UP STUDIES; GENTAMICINS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES; REGISTRIES; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84876969167     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.001170     Document Type: Article

References (48)

1. Olaison L, Schadewitz K. Enterococcal endocarditis in Sweden, 1995-1999: can shorter therapy with aminoglycosides be used?. Clin. Infect. Dis. 2002; 34:159-166.
2. McDonald JR, Olaison L, Anderson D.J., Hoen B., Miro JM, Eykyn S, Abrutyn E, Fowler VG Jr, Habib G, Selton-Suty C, Pappas PA, Cabell C.H., Corey GR, Marco F, Sexton DJ. Enterococcal endocarditis: 107 cases from the International Collaboration on Endocarditis merged database. Am J Med. 2005;118:759-766.
3. Martínez-Marcos F.J., Lomas-Cabezas JM, Hidalgo-Tenorio C, de la Torre-Lima J, Plata-Ciézar A, Reguera-Iglesias JM, Ruiz-Morales J, Márquez-Solero M, Gálvez-Acebal J, de Alarcón- González A; Grupo para el Estudio de las Infecciones Cardiovasculares de la Sociedad Andaluza de Enfermedades Infecciosas. Enterococcal endocarditis: a multicenter study of 76 cases [in Spanish]. Enferm Infecc Microbiol Clin. 2009;27:571-579.
4. Hill EE, Herijgers P, Claus P., Vanderschueren S, Herregods MC, Peetermans WE Infective endocarditis: changing epidemiology and predictors of 6-month mortality: a prospective cohort study. Eur Heart J. 2007;28:196-203.
5. Sy RW, Kritharides L. Health care exposure and age in infective endocarditis: results of a contemporary population-based profile of 1536 patients in Australia. Eur Heart J. 2010;31:1890-1897.
6. Di Salvo G., Thuny F, Rosenberg V., Pergola V, Belliard O, Derumeaux G., Cohen A, Iarussi D, Giorgi R., Casalta JP, Caso P, Habib G. Endocarditis in the elderly: clinical, echocardiographic, and prognostic features. Eur Heart J. 2003;24:1576-1583.
7. Rice LB, Calderwood SB, Eliopoulos G.M., Farber BF, Karchmer AW Enterococcal endocarditis: a comparison of prosthetic and native valve disease. Rev Infect Dis. 1991;13:1-7.
8. Fisher K, Phillips C. The ecology, epidemiology and virulence of Enterococcus. Microbiology. 2009;155(pt 6):1749-1757.
9. Weber SG, Gold HS Enterococcus: an emerging pathogen in hospitals. Semin Respir Crit Care Med. 2003;24:49-60.
10. Megran DW. Enterococcal endocarditis. Clin Infect Dis. 1992;15:63-71.
11. Moreillon P, Que YA Infective endocarditis. Lancet. 2004;363:139-149.
12. Fernández Guerrero ML, Goyenechea A, Verdejo C, Roblas RF, de Górgolas M. Enterococcal endocarditis on native and prosthetic valves: a review of clinical and prognostic factors with emphasis on hospital-acquired infections as a major determinant of outcome. Medicine (Baltimore). 2007;86:363-377.
13. Baddour LM, Wilson WR, Bayer A.S., Fowler VG Jr, Bolger AF, Levison ME, Ferrieri P, Gerber M.A., Tani LY, Gewitz MH, Tong DC, Steckelberg J.M., Baltimore RS, Shulman ST, Burns JC, Falace DA, Newburger JW, Pallasch TJ, Takahashi M, Taubert KA. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation. 2005; 111:e394-e434.
14. Habib G, Hoen B, Tornos P., Thuny F, Prendergast B, Vilacosta I., Moreillon P, De Jesus Antunes M, Thilen U, Lekakis J, Lengyel M, Müller L, Naber CK, Nihoyannopoulos P, Moritz A, Zamorano JL. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC): endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009;30:2369-2413.
15. Murray BE. Vancomycin-resistant enterococcal infections. N Engl J Med. 2000;342:710-721.
16. Moellering Jr. RC Emergence of Enterococcus as a significant pathogen. Clin Infect Dis. 1992;14:1173-1176.
17. Wilson WR, Karchmer AW, Dajani A.S., Taubert KA, Bayer A, Kaye D, Bisno A.L., Ferrieri P., Shulman ST, Durack DT Antibiotic treatment of adults with infective endocarditis due to streptococci, enterococci, staph-ylococci, and HACEK microorganisms: American Heart Association. JAMA. 1995;274:1706-1713.
18. Eliopoulos GM, Eliopoulos CT Therapy of enterococcal infections. Eur J Clin Microbiol Infect Dis. 1990;9:118-126.
19. Graham JC, Gould FK Role of aminoglycosides in the treatment of bacterial endocarditis. J Antimicrob Chemother. 2002;49:437-444.
20. Moellering RC J.r., Watson BK, Kunz LJ Endocarditis due to group D streptococci: comparison of disease caused by Streptococcus bovis with that produced by the enterococci. Am J Med. 1974;57:239-250.
21. Buchholtz K, Larsen CT, Hassager C, Bruun NE Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a prospective observational cohort study of 373 patients. Clin Infect Dis. 2009;48:65-71.
22. Buchholtz K, Larsen CT, Hassager C, Bruun NE Infective endocarditis: long-term reversibility of kidney function impairment: a 1-y postdischarge follow-up study. Scand J Infect Dis. 2010;42:484-490.
23. Baciewicz AM, Sokos DR, Cowan RI Aminoglycoside-associated neph-rotoxicity in the elderly. Ann Pharmacother. 2003;37:182-186.
24. Paterson DL, Robson JM, Wagener MM Risk factors for toxicity in elderly patients given aminoglycosides once daily. J Gen Intern Med. 1998;13:735-739.
25. Li JS, Sexton DJ, Mick N, Nettles R., Fowler VG Jr, Ryan T, Bashore T, Corey GR Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30:633-638.
26. Infective endocarditis: diagnosis and treatment: Danish Society of Cardiology guidelines 2007 [in Danish]. http://cardio.dk/component/docman/doc- download/129-infektios-endokardit?Itemid=247. Accessed April 12, 2012.
27. Siersbaek-Nielsen K., Hansen JM, Kampmann J, Kristensen M. Rapid evaluation of creatinine clearance. Lancet. 1971;1:1133-1134.
28. Kampmann J, Siersbaek-Nielsen K, Kristensen M., Hansen JM Rapid evaluation of creatinine clearance. Acta Med Scand. 1974;196:517-520.
29. Hunter TH. Use of streptomycin in the treatment of bacterial endocarditis. Am J Med. 1947;2:436-442.
30. Jawetz E, Gunnison JB, Coleman VR The combined action of penicillin with streptomycin or chloromycetin on enterococci in vitro. Science. 1950;111:254-256.
31. Henry NK, Wilson WR, Geraci JE Treatment of streptomycin-susceptible en-terococcal experimental endocarditis with combinations of penicillin and low-or high-dose streptomycin. Antimicrob Agents Chemother. 1986;30:725-728.
32. Geraci JE, Martin WJ Antibiotic therapy of bacterial endocarditis, VI: subacute enterococcal endocarditis; clinical, pathologic and therapeutic consideration of 33 cases. Circulation. 1954;10:173-194.
33. Jawetz E, Sonne M. Penicillin-streptomycin treatment of enterococcal endocarditis: a re-evaluation. N Engl J Med. 1966;274:710-715.
34. Wilson WR, Wilkowske CJ, Wright A.J., Sande MA, Geraci JE Treatment of streptomycin-susceptible and streptomycin-resistant enterococcal endocarditis. Ann Intern Med. 1984;100:816-823.
35. Anderson DJ, Olaison L, McDonald J.R., Miro JM, Hoen B, Selton-Suty C, Doco-Lecompte T, Abrutyn E., Habib G, Eykyn S, Pappas P.A., Fowler VG, Sexton DJ, Almela M, Corey GR, Cabell CH. Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database. Eur J Clin Microbiol Infect Dis. 2005;24:665-670.
36. Mandell GL, Kaye D, Levison M.E., Hook EW Enterococcal endocarditis: an analysis of 38 patients observed at the New York Hospital-Cornell Medical Center. Arch Intern Med. 1970;125:258-264.
37. Gavaldà J, Len O, Miró JM, Muñoz P, Montejo M, Alarcón A, de la Torre-Cisneros J, Peña C, Martínez-Lacasa X, Sarria C, Bou G, Aguado JM, Navas E, Romeu J, Marco F, Torres C, Tornos P, Planes A, Falcó V, Almirante B, Pahissa A. Brief communication: treatment of Enterococcus faecalis endocarditis with ampicillin plus ceftriaxone. Ann Intern Med. 2007;146:574-579.
38. Herzstein J, Ryan JL, Mangi R.J., Greco TP, Andriole VT Optimal therapy for enterococcal endocarditis. Am J Med. 1984;76:186-191.
39. Cosgrove SE, Vigliani GA, Fowler VG Jr, Abrutyn E, Corey GR, Levine D.P., Rupp ME, Chambers HF, Karchmer AW, Boucher HW Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic. Clin Infect Dis. 2009;48:713-721.
40. Majumdar A, Chowdhary S, Ferreira M.A., Hammond LA, Howie AJ, Lipkin GW, Littler WA Renal pathological findings in infective endocarditis. Nephrol Dial Transplant. 2000;15:1782-1787.
41. McLean AJ, IoannidesDemos LL, Li S.C., Bastone EB, Spicer WJ Bactericidal effect of gentamicin peak concentration provides a rationale for administration of bolus doses. J Antimicrob Chemother. 1993;32:301-305.
42. Moore RD, Lietman PS, Smith CR Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis. 1987;155:93-99.
43. Buchholtz K, Larsen CT, Schaadt B, Hassager C., Bruun NE Once versus twice daily gentamicin dosing for infective endocarditis: a randomized clinical trial. Cardiology. 2011;119:65-71.
44. Buchholtz K, Larsen CT, Hassager C, Bruun NE In infectious endocarditis patients mortality is highly related to kidney function at time of diagnosis: a prospective observational cohort study of 231 cases. Eur J Intern Med. 2009;20:407-410.
45. Netzer RO, Altwegg SC, Zollinger E, Täuber M, Carrel T., Seiler C. Infective endocarditis: determinants of long term outcome. Heart. 2002;88:61-66.
46. Sy RW, Chawantanpipat C, Richmond D.R., Kritharides L. Development and validation of a time-dependent risk model for predicting mortality in infective endocarditis. Eur Heart J. 2011;32:2016-2026.
47. Khan NA, Ma I, Thompson C.R., Humphries K., Salem DN, Sarnak MJ, Levin A. Kidney function and mortality among patients with left ventricular systolic dysfunction. J Am Soc Nephrol. 2006;17:244-253.
48. Johnson AP, Warner M, Woodford N., Speller DC, Livermore DM Antibiotic resistance among enterococci causing endocarditis in the UK: analysis of isolates referred to a reference laboratory. BMJ. 1998;317:629-630.