Biological dosimetry by automated dicentric scoring in a simulated emergency

Radiation Research

Volumn 179, Issue 5, 2013, Pages 557-569

  Gruel, Gaetan ^a   Grégoire, Eric ^a   Lecas, Sarah ^a   Martin, Cécile ^a   Roch Lefevre, Sandrine ^a   Vaurijoux, Aurélie ^a   Voisin, Pascale ^a   Voisin, Philippe ^a   Barquinero, Joan Francesc ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOMATIC DICENTRIC SCORING; AUTOMATION; BLOOD SAMPLING; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DOSIMETRY; EMERGENCY CARE; EMERGENCY HEALTH SERVICE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; PARTIAL BODY RADIATION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; SCORING SYSTEM; WHOLE BODY RADIATION;

AUTOMATION; CELL COUNT; CHROMOSOME ABERRATIONS; DOSE-RESPONSE RELATIONSHIP, RADIATION; EMERGENCIES; HUMANS; RADIOMETRY; TIME FACTORS; TRIAGE; WHOLE-BODY IRRADIATION;

EID: 84876963636     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR3196.1     Document Type: Article

References (13)

1. Agency IAE. Cytogenetic dosimetry: Applications in preparedness for and response to radiation emergencies. Vienna: IAEA; 2011.
2. Schunck C, Johannes T, Varga D, Lorch T, Plesch A. New developments in automated cytogenetic imaging: unattended scoring of dicentric chromosomes, micronuclei, single cell gel electrophoresis, and fluorescence signals. Cytogenet Genome Res. 2004; 104:383-9. (Pubitemid 38721107)
3. Lloyd DC, Edwards AA, Moquet JE, Guerrero-Carbajal YC. The role of cytogenetics in early triage of radiation casualties. Appl Radiat Isot. 2000; 52:1107-12. (Pubitemid 30209982)
4. Voisin P, Benderitter M, Claraz M, Chambrette V, Sorokine-Durm I, Delbos M, et al. The cytogenetic dosimetry of recent accidental overexposure. Cell Mol Biol (Noisy-le-grand). 2001; 47:557-64.
5. Miller SM, Ferrarotto CL, Vlahovich S, Wilkins RC, Boreham DR, Dolling JA. Canadian Cytogenetic Emergency network (CEN) for biological dosimetry following radiological/nuclear accidents. Int J Radiat Biol. 2007; 83:471-7. (Pubitemid 46854839)
6. Romm H, Wilkins RC, Coleman CN, Lillis-Hearne PK, Pellmar TC, Livingston GK, et al. Biological dosimetry by the triage dicentric chromosome assay: potential implications for treatment of acute radiation syndrome in radiological mass casualties. Radiat Res. 2011; 175:397-404.
7. Prasanna PG, Moroni M, Pellmar TC. Triage dose assessment for partial-body exposure: dicentric analysis. Health Phys. 2010; 98:244-51.
8. Vaurijoux A, Gruel G, Pouzoulet F, Gregoire E, Martin C, Roch-Lefevre S, et al. Strategy for population triage based on dicentric analysis. Radiat Res. 2009; 171:541-8.
9. Vaurijoux A, Gregoire E, Roch-Lefevre S, Voisin P, Martin C, Roy L, et al. Detection of partial-body exposure to ionizing radiation by the automatic detection of dicentrics. Radiat Res. 2012; 178:357-64.
10. Di Giorgio M, Barquinero JF, Vallerga MB, Radl A, Taja MR, Seoane A, et al. Biological dosimetry intercomparison exercise: an evaluation of triage and routine mode results by robust methods. Radiat Res. 2011;175(5):638-49.
11. Waselenko JK, MacVittie TJ, Blakely WF, Pesik N, Wiley AL, Dickerson WE, et al. Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group. Ann Intern Med. 2004; 140:1037-51.
12. Standardization IOf. General requirements for the competence of testing and calibration laboratories. Geneva: ISO; 2005.
13. Barquinero JF, Barrios L, Caballin MR, Miro R, Ribas M, Egozcue J. Biological dosimetry in simulated in vitro partial irradiations. Int J Radiat Biol. 1997; 71:435-40. (Pubitemid 27187400)