Prevalence and factors associated with probable HIV dementia in an African population: A cross-sectional study of an HIV/AIDS clinic population

BMC Psychiatry

Volumn 13, Issue , 2013, Pages

  Nakku, Juliet ^a   Kinyanda, Eugene ^b   Hoskins, Susan ^c  

^a MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES   (Uganda)

^b MRC/UVRI Uganda Research Unit   (Uganda)

^c MRC CLINICAL TRIALS UNIT   (United Kingdom)

Author keywords

Africa; HIV dementia; HIV AIDS; Neuro cognitive impairment; Stress

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AFRICA SOUTH OF THE SAHARA; AFRICAN AMERICAN; AGE DISTRIBUTION; ALCOHOLISM; ARTICLE; BODY MASS; CD4 LYMPHOCYTE COUNT; CLINICAL ASSESSMENT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMOGRAPHY; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEALTH; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERNATIONAL DEMENTIA SCALE; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; MENTAL STRESS; PREVALENCE; PROBABILITY; PSYCHOLOGIC ASSESSMENT; PSYCHOSOCIAL CARE; RATING SCALE; SOCIAL ASPECT; UGANDA; AIDS DEMENTIA COMPLEX; EPIDEMIOLOGY; HEALTH SURVEY; HIV INFECTIONS; MIDDLE AGED; PSYCHOLOGY; RISK FACTOR; YOUNG ADULT;

ADULT; AIDS DEMENTIA COMPLEX; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CROSS-SECTIONAL STUDIES; FEMALE; HEALTH SURVEYS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PREVALENCE; RISK FACTORS; UGANDA; YOUNG ADULT;

EID: 84876962437     PISSN: None     EISSN: 1471244X     Source Type: Journal    
DOI: 10.1186/1471-244X-13-126     Document Type: Article

References (20)

1. UNAIDS Global Report: UNAIDS Report on the Global AIDS Epidemic 2010, http://www.unaids.org/documents/20101123_globalreport_em.pdf, UNAIDS.
2. Chandler G, Himelhoch S, Moore RD. Substance Abuse and Psychiatric Disorders in HIV-positive patients: epidemiology and impact on antiretroviral therapy. Drugs 2006, 66(6):769-789. 10.2165/00003495-200666060-00004, 16706551.
3. Wilkie FL, Goodkin K, Eisdorfer C, Feaster D, Morgan R, Fletcher MA, Blaney N, Baum M, Szapocznik J. Mild Cognitive impairment and risk of mortality in HIV-1 infection. J Neuropsychiatry Clin Neuroscience 1998, 10(2):125-132.
4. Antinori A, Arendt G, Becker JT. Updated research nosology for HIV associated neurocognitive disorders. Neurology 69:1789-1799.
5. Sacktor NC, Wong M, Nakasujja N, Skolasky RL, Selnes OA, Musisi S, Robertson K, McArthur JC, Ronald A, Katabira ET. The International HIV Dementia Scale: A new rapid screening test for HIV dementia. AIDS 2005, 19(13):1367-1374.
6. Sheehan D, Lucrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, Herqueta T, Baker R, Dunbar GC. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSMIV and ICD-10. J Clin Psychiatry 1998, 59(suppl 20):22-33.
7. Kinyanda E, Hoskins S, Nakku J, Nawaz S, Patel V. Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda. BMC Psychiatry 2011, 11:205. 10.1186/1471-244X-11-205, 3260105, 22208452.
8. Singh D, Sunpath H, John S, Eastham L, Gouden R. The utility of a rapid screening tool for depression and HIV dementia amongst patients with low CD4 counts- a preliminary report. Afr J Psychiatry 2008, 11(4):282-286.
9. Watson M, Greer S, Young J, Inayat Q, Burgess C, Robertson B. The development of a questionnaire measure of adjustment to cancer: the MAC. Psychol Med 1988, 18(1):203-209. 10.1017/S0033291700002026, 3363039.
10. Kerkhof AJFM, Bernasco W, Bille-Brahe U, Platt S, Schmidtke A. A WHO/EURO Multicentre study on parasuicide. European Parasuicide study interview schedule. EPSIS I version 6.2 1989, The Netherlands: Department of Clinical and Health Psychology, University of Leiden, Schiødt H, Aagaard B.
11. Kinyanda E, Hjelmeland H, Musisi S. Life events in deliberate self-harm as seen in African population in Uganda. Crisis 2005, 26(1):4-11.
12. Wong MH, Robertson K, Nakasujja N, Skolasky R, Musisi S, Katabira E, McArthur J, Ronald A, Sacktor N. Frequency of and risk factors for HIV dementia in an HIV clinic in Sub-Saharan Africa. Neurology 2007, 68:350-355. 10.1212/01.wnl.0000252811.48891.6d, 17261681.
13. Childs EA, Lyles RH, Selnes OA, Chen B, Miller EN, Cohen BA, Becker JT, Mellors J, McArthur JC. Plasma viral load and CD4 lymphocytes predict HIV-associated dementia and sensory neuropathy. Neurology 1999, 52:607-613. 10.1212/WNL.52.3.607, 10025796.
14. Becker JT, Lopez OL, Dew MA, Aizestein HJ. Prevalence of cognitive disorders differs as a function of age in HIV virus infection. AIDS 18(1):11-18.
15. Nakasujja N, Skolasky LR, Musisi S, Allebeck P, Robertson K, Ronald A, Katabira ET, Clifford DB, Sacktor N. Depression Symptoms and Cognitive function among individuals with advanced HIV infection initiating HAART in Uganda. BMC Psychiatry 2010, 10:44. 10.1186/1471-244X-10-44, 2901316, 20537129.
16. Tozzi V, Balestra P, Lorenzini P, Bellagamba R, Galgani S, Corpolongo A, Vlassi C, Larussa D, Zaccarelli M, Noto P, Visco-Comandini U, Giulianelli M, Ippolito G, Antinori A, Narciso P. Prevalence and risk factors for human immunodeficiency virus associated neurocognitive impairment, 1996 to 2002: Results from an urban observational cohort. J Neurovirol 2005, 11:265-273. 10.1080/13550280590952790, 16036806.
17. Diagnostic and statistical manual of mental disorders 1994, Washington DC: American Psychiatric Association, Fourth, Diagnostic and statistical manual of mental disorders.
18. Starace F, Bartoli L, Aloisi M. Cognitive and affective disorders associated to HIV infection in the HAART era: Findings from the NeuroICONA study. Acta Psychiatr Scand 2002, 106(1):20-26. 10.1034/j.1600-0447.2002.02289.x, 12100344.
19. Ironson HG, Hayward H. Do positive psychosocial factors predict disease progression in HIV-1? A review of evidence. Psychosom Med 2008 June, 70(5):546-554.
20. Pukay-Martin DN, Cristiani AS, Saveanu R, Bornstein AR. The relationship between stressful life events and cognitive function in HIV-infected men. Journal of Neuropsychiatry Clinical Neuroscience 2000, 15(4):436-440.