메뉴 건너뛰기




Volumn 280, Issue 9, 2013, Pages 2014-2026

Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression

Author keywords

ORMDL3; p300; STAT6; Th2 cytokines; transcription regulation

Indexed keywords

DNA FRAGMENT; E1A ASSOCIATED P300 PROTEIN; GENOMIC DNA; INTERLEUKIN 13; INTERLEUKIN 4; STAT6 PROTEIN;

EID: 84876909941     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12225     Document Type: Article
Times cited : (26)

References (60)
  • 5
    • 84862772501 scopus 로고    scopus 로고
    • Asthma and bronchodilator responsiveness are associated with polymorphic markers of ARG1, CRHR2 and chromosome 17q21
    • Sy HY, Ko FW, Chu HY, Chan IH, Wong GW, Hui DS, &, Leung TF, (2012) Asthma and bronchodilator responsiveness are associated with polymorphic markers of ARG1, CRHR2 and chromosome 17q21. Pharmacogenet Genomics 22, 517-524.
    • (2012) Pharmacogenet Genomics , vol.22 , pp. 517-524
    • Sy, H.Y.1    Ko, F.W.2    Chu, H.Y.3    Chan, I.H.4    Wong, G.W.5    Hui, D.S.6    Leung, T.F.7
  • 9
    • 41549111983 scopus 로고    scopus 로고
    • A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications
    • DOI 10.1016/j.jaci.2008.01.015, PII S0091674908001462
    • Tavendale R, Macgregor DF, Mukhopadhyay S, &, Palmer CN, (2008) A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol 121, 860-863. (Pubitemid 351471721)
    • (2008) Journal of Allergy and Clinical Immunology , vol.121 , Issue.4 , pp. 860-863
    • Tavendale, R.1    Macgregor, D.F.2    Mukhopadhyay, S.3    Palmer, C.N.A.4
  • 10
    • 62449114842 scopus 로고    scopus 로고
    • Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma
    • Wu H, Romieu I, Sienra-Monge JJ, Li H, del Rio-Navarro BE, &, London SJ, (2009) Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy 64, 629-635.
    • (2009) Allergy , vol.64 , pp. 629-635
    • Wu, H.1    Romieu, I.2    Sienra-Monge, J.J.3    Li, H.4    Del Rio-Navarro, B.E.5    London, S.J.6
  • 15
    • 38949188741 scopus 로고    scopus 로고
    • Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection
    • Madore AM, Tremblay K, Hudson TJ, &, Laprise C, (2008) Replication of an association between 17q21 SNPs and asthma in a French-Canadian familial collection. Hum Genet 123, 93-95.
    • (2008) Hum Genet , vol.123 , pp. 93-95
    • Madore, A.M.1    Tremblay, K.2    Hudson, T.J.3    Laprise, C.4
  • 16
    • 84888130450 scopus 로고    scopus 로고
    • Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma
    • doi: 10.1038/tpj.2012.36
    • Berce V, Kozmus CE, &, Potocnik U, (2012) Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma. Pharmacogenomics J. doi: 10.1038/tpj.2012.36.
    • (2012) Pharmacogenomics J
    • Berce, V.1    Kozmus, C.E.2    Potocnik, U.3
  • 17
    • 80255126299 scopus 로고    scopus 로고
    • Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population
    • Fang Q, Zhao H, Wang A, Gong Y, &, Liu Q, (2011) Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population. BMC Med Genet 12, 133.
    • (2011) BMC Med Genet , vol.12 , pp. 133
    • Fang, Q.1    Zhao, H.2    Wang, A.3    Gong, Y.4    Liu, Q.5
  • 19
    • 84865361745 scopus 로고    scopus 로고
    • GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophIL-mediated bronchial hyperresponsiveness
    • Kang MJ, Yu HS, Seo JH, Kim HY, Jung YH, Kim YJ, Kim HJ, Lee SY, &, Hong SJ, (2012) GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophIL-mediated bronchial hyperresponsiveness. Hum Immunol 73, 954-959.
    • (2012) Hum Immunol , vol.73 , pp. 954-959
    • Kang, M.J.1    Yu, H.S.2    Seo, J.H.3    Kim, H.Y.4    Jung, Y.H.5    Kim, Y.J.6    Kim, H.J.7    Lee, S.Y.8    Hong, S.J.9
  • 20
    • 80052961827 scopus 로고    scopus 로고
    • Relationship between the 17q21 locus and adult asthma in a Czech population
    • Hrdlickova B, &, Holla LI, (2011) Relationship between the 17q21 locus and adult asthma in a Czech population. Hum Immunol 72, 921-925.
    • (2011) Hum Immunol , vol.72 , pp. 921-925
    • Hrdlickova, B.1    Holla, L.I.2
  • 21
    • 84861575931 scopus 로고    scopus 로고
    • 17q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom
    • Marinho S, Custovic A, Marsden P, Smith JA, &, Simpson A, (2012) 17q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom. Ann Allergy Asthma Immunol 108, 402-411.
    • (2012) Ann Allergy Asthma Immunol , vol.108 , pp. 402-411
    • Marinho, S.1    Custovic, A.2    Marsden, P.3    Smith, J.A.4    Simpson, A.5
  • 22
    • 84874948596 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the ORM1-like 3 gene associated with childhood asthma in a Chinese population
    • Yang FF, Huang Y, Li QB, Dai JH, &, Fu Z, (2012) Single nucleotide polymorphisms in the ORM1-like 3 gene associated with childhood asthma in a Chinese population. Genet Mol Res 11, 4646-4653.
    • (2012) Genet Mol Res , vol.11 , pp. 4646-4653
    • Yang, F.F.1    Huang, Y.2    Li, Q.B.3    Dai, J.H.4    Fu, Z.5
  • 33
    • 77649150074 scopus 로고    scopus 로고
    • The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
    • Cantero-Recasens G, Fandos C, Rubio-Moscardo F, Valverde MA, &, Vicente R, (2010) The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Hum Mol Genet 19, 111-121.
    • (2010) Hum Mol Genet , vol.19 , pp. 111-121
    • Cantero-Recasens, G.1    Fandos, C.2    Rubio-Moscardo, F.3    Valverde, M.A.4    Vicente, R.5
  • 34
    • 79957835071 scopus 로고    scopus 로고
    • Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion
    • Lluis A, Schedel M, Liu J, Illi S, Depner M, von Mutius E, Kabesch M, &, Schaub B, (2011) Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion. J Allergy Clin Immunol 127, 1587-1594.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1587-1594
    • Lluis, A.1    Schedel, M.2    Liu, J.3    Illi, S.4    Depner, M.5    Von Mutius, E.6    Kabesch, M.7    Schaub, B.8
  • 36
    • 0033168958 scopus 로고    scopus 로고
    • P300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6
    • DOI 10.1093/nar/27.13.2722
    • Gingras S, Simard J, Groner B, &, Pfitzner E, (1999) p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6. Nucleic Acids Res 27, 2722-2729. (Pubitemid 29306570)
    • (1999) Nucleic Acids Research , vol.27 , Issue.13 , pp. 2722-2729
    • Gingras, S.1    Simard, J.2    Groner, B.3    Pfitzner, E.4
  • 37
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides H, &, Reich NC, (1993) Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 262, 1265-1267. (Pubitemid 24036092)
    • (1993) Science , vol.262 , Issue.5137 , pp. 1265-1267
    • Kotanides, H.1    Reich, N.C.2
  • 38
    • 79955574671 scopus 로고    scopus 로고
    • Transcriptional regulation by STAT6
    • Goenka S, &, Kaplan MH, (2011) Transcriptional regulation by STAT6. Immunol Res 50, 87-96.
    • (2011) Immunol Res , vol.50 , pp. 87-96
    • Goenka, S.1    Kaplan, M.H.2
  • 39
    • 0027972046 scopus 로고
    • An interleukin-4-induced transcription factor: IL-4 Stat
    • Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, &, McKnight SL, (1994) An interleukin-4-induced transcription factor: IL-4 Stat. Science 265, 1701-1706. (Pubitemid 24314900)
    • (1994) Science , vol.265 , Issue.5179 , pp. 1701-1706
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3    Ho, T.C.4    Brasseur, M.5    McKnight, S.L.6
  • 40
    • 0029057858 scopus 로고
    • Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis
    • Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K, et al,. (1995) Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Mol Cell Biol 15, 3336-3343.
    • (1995) Mol Cell Biol , vol.15 , pp. 3336-3343
    • Quelle, F.W.1    Shimoda, K.2    Thierfelder, W.3    Fischer, C.4    Kim, A.5    Ruben, S.M.6    Cleveland, J.L.7    Pierce, J.H.8    Keegan, A.D.9    Nelms, K.10
  • 41
    • 0033427612 scopus 로고    scopus 로고
    • Ectopic expression of activated Stat6 induces the expression of Th2- specific cytokines and transcription factors in developing Th1 cells
    • Kurata H, Lee HJ, O'Garra A, &, Arai N, (1999) Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells. Immunity 11, 677-688. (Pubitemid 30030707)
    • (1999) Immunity , vol.11 , Issue.6 , pp. 677-688
    • Kurata, H.1    Hyun, J.L.2    O'Garra, A.3    Arai, N.4
  • 42
    • 0034640404 scopus 로고    scopus 로고
    • A gain-of-function mutation in STAT6
    • Daniel C, Salvekar A, &, Schindler U, (2000) A gain-of-function mutation in STAT6. J Biol Chem 275, 14255-14259.
    • (2000) J Biol Chem , vol.275 , pp. 14255-14259
    • Daniel, C.1    Salvekar, A.2    Schindler, U.3
  • 43
    • 0032934156 scopus 로고    scopus 로고
    • Functional roles of STAT family proteins: Lessons from knockout mice
    • Akira S, (1999) Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells 17, 138-146. (Pubitemid 29226664)
    • (1999) Stem Cells , vol.17 , Issue.3 , pp. 138-146
    • Akira, S.1
  • 46
  • 51
    • 84857054959 scopus 로고    scopus 로고
    • IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1,2/Stat6 signal transduction pathway: Implication for atopic dermatitis
    • Bao L, Shi VY, &, Chan LS, (2012) IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1,2/Stat6 signal transduction pathway: implication for atopic dermatitis. Mol Immunol 50, 91-97.
    • (2012) Mol Immunol , vol.50 , pp. 91-97
    • Bao, L.1    Shi, V.Y.2    Chan, L.S.3
  • 52
    • 77956587592 scopus 로고    scopus 로고
    • IL-13 upregulates GPIIb expression in megakaryocytic cell lines via STAT6
    • Shi X, Cai W, Zhou Y, Zhang X, Xiong L, Li R, Yu X, &, Li W, (2010) IL-13 upregulates GPIIb expression in megakaryocytic cell lines via STAT6. Anat Rec (Hoboken) 293, 1470-1476.
    • (2010) Anat Rec (Hoboken) , vol.293 , pp. 1470-1476
    • Shi, X.1    Cai, W.2    Zhou, Y.3    Zhang, X.4    Xiong, L.5    Li, R.6    Yu, X.7    Li, W.8
  • 53
    • 77951234171 scopus 로고    scopus 로고
    • Identification and characterization of rat RhoA gene promoter
    • Chiba Y, Goto K, Matsusue K, Kimura S, &, Misawa M, (2010) Identification and characterization of rat RhoA gene promoter. J Pharmacol Sci 112, 467-472.
    • (2010) J Pharmacol Sci , vol.112 , pp. 467-472
    • Chiba, Y.1    Goto, K.2    Matsusue, K.3    Kimura, S.4    Misawa, M.5
  • 55
    • 80052030946 scopus 로고    scopus 로고
    • Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: Characterisation and selection of candidates for pre-clinical development
    • Healey GD, Zinnen S, Lockridge JA, Richards I, Evans N, &, Walker W, (2010) Identification of small interfering RNA targeting Signal Transducer and Activator of Transcription 6: characterisation and selection of candidates for pre-clinical development. J RNAi Gene Silencing 6, 401-410.
    • (2010) J RNAi Gene Silencing , vol.6 , pp. 401-410
    • Healey, G.D.1    Zinnen, S.2    Lockridge, J.A.3    Richards, I.4    Evans, N.5    Walker, W.6
  • 57
    • 0028222522 scopus 로고
    • The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms
    • Immenschuh S, Nagae Y, Satoh H, Baumann H, &, Muller-Eberhard U, (1994) The rat and human hemopexin genes contain an identical interleukin-6 response element that is not a target of CAAT enhancer-binding protein isoforms. J Biol Chem 269, 12654-12661. (Pubitemid 24202055)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.17 , pp. 12654-12661
    • Immenschuh, S.1    Nagael, Y.2    Satoh, H.3    Baumann, H.4    Muller-Eberhard, U.5
  • 58
    • 0028211553 scopus 로고
    • The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements
    • Yuan J, Wegenka UM, Lutticken C, Buschmann J, Decker T, Schindler C, Heinrich PC, &, Horn F, (1994) The signalling pathways of interleukin-6 and gamma interferon converge by the activation of different transcription factors which bind to common responsive DNA elements. Mol Cell Biol 14, 1657-1668. (Pubitemid 24074561)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.3 , pp. 1657-1668
    • Yuan, J.1    Wegenka, U.M.2    Lutticken, C.3    Buschmann, J.4    Decker, T.5    Schindler, C.6    Heinrich, P.C.7    Horn, F.8
  • 60
    • 68749108259 scopus 로고    scopus 로고
    • LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
    • Wang Y, Zhang H, Chen Y, Sun Y, Yang F, Yu W, Liang J, Sun L, Yang X, Shi L, et al,. (2009) LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 138, 660-672.
    • (2009) Cell , vol.138 , pp. 660-672
    • Wang, Y.1    Zhang, H.2    Chen, Y.3    Sun, Y.4    Yang, F.5    Yu, W.6    Liang, J.7    Sun, L.8    Yang, X.9    Shi, L.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.