Early local swelling and tenderness are associated with large-joint damage after 8 years of treatment to target in patients with recent-onset rheumatoid arthritis

Journal of Rheumatology

Volumn 40, Issue 5, 2013, Pages 624-629

  Van Den Broek, Marianne ^a   Dirven, Linda ^a   Kroon, Herman M ^a   Kloppenburg, Margreet ^a   Ronday, H Karel ^b   Peeters, André J ^c   Kerstens, Pit J S M ^d   Huizinga, Tom W J ^a   Lems, Willem F ^d,e   Allaart, Cornelia F ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b HAGA HOSPITAL   (Netherlands)

^c Haga Hospital ^*  (Netherlands)

^d Jan Van Breemen Research Institute   (Netherlands)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Large joint damage; Larsen score; Rheumatoid arthritis; Synovitis; Treat to target

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; INFLIXIMAB; PREDNISONE;

ADULT; AGE DISTRIBUTION; ANKLE; ARTHROPATHY; ARTICLE; ATTRIBUTABLE RISK; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DRUG EFFICACY; ELBOW; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FUNCTIONAL DISEASE; HEALTH ASSESSMENT QUESTIONNAIRE; HUMAN; JOINT SWELLING; JOINT TENDERNESS; KNEE; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SHOULDER; TREATMENT RESPONSE; WRIST;

LARGE-JOINT DAMAGE; LARSEN SCORE; RHEUMATOID ARTHRITIS; SYNOVITIS; TREAT TO TARGET;

ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISABILITY EVALUATION; DRUG THERAPY, COMBINATION; EDEMA; FEMALE; HEALTH STATUS; HUMANS; JOINTS; MALE; METHOTREXATE; MIDDLE AGED; PREDNISOLONE; QUESTIONNAIRES; RECOVERY OF FUNCTION; SEVERITY OF ILLNESS INDEX;

EID: 84876909228     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.121248     Document Type: Article

References (17)

1. Boers M, Kostense PJ, Verhoeven AC, van der Linden S. Inflammation and damage in an individual joint predict further damage in that joint in patients with early rheumatoid arthritis. Arthritis Rheum 2001;44:2242-6. (Pubitemid 32977491)
2. Klarenbeek NB, Guler-Yuksel M, van der Heijde DM, Hulsmans HM, Kerstens PJ, Molenaar TH, et al. Clinical synovitis in a particular joint is associated with progression of erosions and joint space narrowing in that same joint, but not in patients initially treated with infliximab. Ann Rheum Dis 2010;69:2107-13.
3. Linn-Rasker SP, van der Helm-van Mil AH, Breedveld FC, Huizinga TW. Arthritis of the large joints - in particular, the knee - at first presentation is predictive for a high level of radiological destruction of the small joints in rheumatoid arthritis. Ann Rheum Dis 2007;66:646-50. (Pubitemid 46707134)
4. Drossaers-Bakker KW, Kroon HM, Zwinderman AH, Breedveld FC, Hazes JM. Radiographic damage of large joints in long-term rheumatoid arthritis and its relation to function. Rheumatology 2000;39:998-1003.
5. Kuper HH, van Leeuwen MA, van Riel PL, Prevoo ML, Houtman PM, Lolkema WF, et al. Radiographic damage in large joints in early rheumatoid arthritis: Relationship with radiographic damage in hands and feet, disease activity, and physical disability. Br J Rheumatol 1997;36:855-60.
6. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24. (Pubitemid 18091653)
7. Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, van Zeben D, Kerstens PJ, Hazes JM, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial. Arthritis Rheum 2008;58 Suppl:S126-S135.
8. Dirven L, van den Broek M, Kroon HM, Grillet BA, Han KH, Kerstens PJ, et al. Large-joint damage in patients with early rheumatoid arthritis and its association with treatment strategy and damage of the small joints. Rheumatology 2012;51:2262-8.
9. Larsen A. A radiological method for grading the severity of rheumatoid arthritis. Scand J Rheumatol 1975;4:225-33.
10. Bruce B, Fries JF. The Health Assessment Questionnaire (HAQ). Clin Exp Rheumatol 2005;23 Suppl 39:S14-8. (Pubitemid 46657507)
11. Conaghan PG, O'Connor P, McGonagle D, Astin P, Wakefield RJ, Gibbon WW, et al. Elucidation of the relationship between synovitis and bone damage: A randomized magnetic resonance imaging study of individual joints in patients with early rheumatoid arthritis. Arthritis Rheum 2003;48:64-71. (Pubitemid 36091649)
12. De Rycke L, Peene I, Hoffman IE, Kruithof E, Union A, Meheus L, et al. Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: Diagnostic value, associations with radiological progression rate, and extra-articular manifestations. Ann Rheum Dis 2004;63:1587-93. (Pubitemid 39573686)
13. van den Broek M, Dirven L, Klarenbeek N, Molenaar T, Han K, Kerstens P, et al. The association of treatment response and joint damage with ACPA-status in recent-onset RA: A subanalysis of the 8-year follow-up of the BeSt study. Ann Rheum Dis 2012;71:245-8.
14. Pope JE, Khanna D, Norrie D, Ouimet JM. The minimally important difference for the Health Assessment Questionnaire in rheumatoid arthritis clinical practice is smaller than in randomized controlled trials. J Rheumatol 2009;36:254-9.
15. Drossaers-Bakker KW, de Buck M, van Zeben D, Zwinderman AH, Breedveld FC, Hazes JM. Long-term course and outcome of functional capacity in rheumatoid arthritis: The effect of disease activity and radiologic damage over time. Arthritis Rheum 1999;42:1854-60. (Pubitemid 30257749)
16. Mottonen TT. Prediction of erosiveness and rate of development of new erosions in early rheumatoid arthritis. Ann Rheum Dis 1988;47:648-53.
17. Scott DL, Coulton BL, Popert AJ. Long term progression of joint damage in rheumatoid arthritis. Ann Rheum Dis 1986;45:373-8. (Pubitemid 16121712)