Enhanced sialylation and in vivo efficacy of recombinant human α-galactosidase through in vitro glycosylation

BMB Reports

Volumn 46, Issue 3, 2013, Pages 157-162

  Sohn, Youngsoo ^a,c   Lee, Jung Mi ^b   Park, Heung Rok ^c   Jung, Sung Chul ^d   Park, Tai Hyun ^a   Oh, Doo Byoung ^b  

^a Seoul National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Isu Abxis Co Ltd   (South Korea)

^d Ewha Womans University School of Medicine   (South Korea)

Author keywords

Alpha galactosidase A; Enzyme replacement therapy; Fabry disease; In vitro glycosylation; Sialic acid

Indexed keywords

ALPHA GALACTOSIDASE; N ACETYLNEURAMINIC ACID; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CHO CELL; GLYCOSYLATION; HAMSTER; HUMAN; IN VITRO STUDY; ISOELECTRIC POINT; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ALPHA-GALACTOSIDASE; ANIMALS; CHO CELLS; CRICETINAE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSYLATION; HUMANS; ISOELECTRIC POINT; N-ACETYLNEURAMINIC ACID; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS; MUS;

EID: 84876861105     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2013.46.3.192     Document Type: Article

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