-
1
-
-
33644825856
-
Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line
-
Grothey A, Sargent D. Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. J. Clin. Oncol. 23(36), 9441-9442 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.36
, pp. 9441-9442
-
-
Grothey, A.1
Sargent, D.2
-
2
-
-
36849064682
-
Adjuvant chemotherapy versus observation in patients with colorectal cancer: A randomised study
-
Gray R, Barnwell J, McConkey C, Hills RK, Williams NS, Kerr DJ. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet 370(9604), 2020-2029 (2007).
-
(2007)
Lancet
, vol.370
, Issue.9604
, pp. 2020-2029
-
-
Gray, R.1
Barnwell, J.2
McConkey, C.3
Hills, R.K.4
Williams, N.S.5
Kerr, D.J.6
-
3
-
-
84876821488
-
The efficacy of oxaliplatin (Ox) when added to 5-fluorouracil/leucovorin (FU/L) in stage II colon cancer
-
Chicago, IL, USA, 3-7 June 2011 (Abstract 3507
-
Yothers GA, Allegra CJ, O'Connell MJ et al. The efficacy of oxaliplatin (Ox) when added to 5-fluorouracil/leucovorin (FU/L) in stage II colon cancer. American Society of Clinical Oncology Annual Meeting. Chicago, IL, USA, 3-7 June 2011 (Abstract 3507).
-
American Society of Clinical Oncology Annual Meeting
-
-
Yothers, G.A.1
Allegra, C.J.2
O'Connell, M.J.3
-
4
-
-
77954748953
-
Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracilbased adjuvant therapy in colon cancer
-
Sargent DJ, Marsoni S, Monges G et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracilbased adjuvant therapy in colon cancer. J. Clin. Oncol. 28(20), 3219-3226 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.20
, pp. 3219-3226
-
-
Sargent, D.J.1
Marsoni, S.2
Monges, G.3
-
5
-
-
67650315187
-
Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial
-
André T, Boni C, Navarro M et al. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J. Clin. Oncol. 27(19), 3109-3116 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.19
, pp. 3109-3116
-
-
André, T.1
Boni, C.2
Navarro, M.3
-
6
-
-
70349859888
-
Concordance with NCCN Colorectal Cancer Guidelines and ASCO/NCCN Quality Measures: An NCCN institutional analysis
-
Romanus D, Weiser MR, Skibber JM et al. Concordance with NCCN Colorectal Cancer Guidelines and ASCO/NCCN Quality Measures: an NCCN institutional analysis. J. Natl Compr. Canc. Netw. 7(8), 895-904 (2009).
-
(2009)
J. Natl Compr. Canc. Netw.
, vol.7
, Issue.8
, pp. 895-904
-
-
Romanus, D.1
Weiser, M.R.2
Skibber, J.M.3
-
7
-
-
2542615200
-
Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
André T, Boni C, Mounedji-Boudiaf L et al.; Multicenter International Study of Oxaliplatin/5-Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon Cancer (MOSAIC) Investigators. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N. Engl. J. Med. 350(23), 2343-2351 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, Issue.23
, pp. 2343-2351
-
-
André, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
-
8
-
-
80053619762
-
Oxaliplatin as adjuvant therapy for colon cancer: Updated results of NSABP C-07 trial, including survival and subset analyses
-
Yothers G, O'Connell MJ, Allegra CJ et al. Oxaliplatin as adjuvant therapy for colon cancer: updated results of NSABP C-07 trial, including survival and subset analyses. J. Clin. Oncol. 29(28), 3768-3774 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.28
, pp. 3768-3774
-
-
Yothers, G.1
O'Connell, M.J.2
Allegra, C.J.3
-
9
-
-
79955040540
-
Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer
-
Haller DG, Tabernero J, Maroun J et al. Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer. J. Clin. Oncol. 29(11), 1465-1471 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.11
, pp. 1465-1471
-
-
Haller, D.G.1
Tabernero, J.2
Maroun, J.3
-
10
-
-
84860452474
-
Capecitabine versus 5-fluorouracil/ folinic acid as adjuvant therapy for stage III colon cancer: Final results from the X-ACT trial with analysis by age and preliminary evidence of a pharmacodynamic marker of efficacy
-
Twelves C, Scheithauer W, McKendrick J et al. Capecitabine versus 5-fluorouracil/ folinic acid as adjuvant therapy for stage III colon cancer: final results from the X-ACT trial with analysis by age and preliminary evidence of a pharmacodynamic marker of efficacy. Ann. Oncol. 23(5), 1190-1197 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, Issue.5
, pp. 1190-1197
-
-
Twelves, C.1
Scheithauer, W.2
McKendrick, J.3
-
11
-
-
34548160680
-
Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: Results of CALGB 89803
-
Saltz LB, Niedzwiecki D, Hollis D et al. Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J. Clin. Oncol. 25(23), 3456-3461 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.23
, pp. 3456-3461
-
-
Saltz, L.B.1
Niedzwiecki, D.2
Hollis, D.3
-
12
-
-
67650290547
-
Randomized Phase III trial comparing biweekly infusional fluorouracil/ leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3
-
Van Cutsem E, Labianca R, Bodoky G et al. Randomized Phase III trial comparing biweekly infusional fluorouracil/ leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3. J. Clin. Oncol. 27(19), 3117-3125 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.19
, pp. 3117-3125
-
-
Van Cutsem, E.1
Labianca, R.2
Bodoky, G.3
-
13
-
-
84873328631
-
Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial
-
Allegra CJ, Yothers G, O'Connell MJ et al. Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial. J. Clin. Oncol. 31(3), 359-364 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.3
, pp. 359-364
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
-
14
-
-
84870244259
-
Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): A Phase 3 randomised controlled trial
-
de Gramont A, Van Cutsem E, Schmoll HJ et al. Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a Phase 3 randomised controlled trial. Lancet Oncol. 13(12), 1225-1233 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, Issue.12
, pp. 1225-1233
-
-
De Gramont, A.1
Van Cutsem, E.2
Schmoll, H.J.3
-
15
-
-
79951977298
-
Lessons from the adjuvant bevacizumab trial on colon cancer: What next?
-
Van Cutsem E, Lambrechts D, Prenen H, Jain RK, Carmeliet P. Lessons from the adjuvant bevacizumab trial on colon cancer: what next? J. Clin. Oncol. 29(1), 1-4 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.1
, pp. 1-4
-
-
Van Cutsem, E.1
Lambrechts, D.2
Prenen, H.3
Jain, R.K.4
Carmeliet, P.5
-
16
-
-
79953244361
-
Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
-
Ebos JM, Kerbel RS. Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat. Rev. Clin. Oncol. 8(4), 210-221 (2011).
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, Issue.4
, pp. 210-221
-
-
Ebos, J.M.1
Kerbel, R.S.2
-
17
-
-
84859403854
-
Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: A randomized trial
-
Alberts SR, Sargent DJ, Nair S et al. Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. JAMA 307(13), 1383-1393 (2012).
-
(2012)
JAMA
, vol.307
, Issue.13
, pp. 1383-1393
-
-
Alberts, S.R.1
Sargent, D.J.2
Nair, S.3
-
18
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N. Engl. J. Med. 359(17), 1757-1765 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, Issue.17
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
19
-
-
84869108068
-
Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04
-
Ngan SY, Burmeister B, Fisher RJ et al. Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04. J. Clin. Oncol. 30(31), 3827-3833 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.31
, pp. 3827-3833
-
-
Ngan, S.Y.1
Burmeister, B.2
Fisher, R.J.3
-
20
-
-
84863106037
-
Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: Initial results of the German CAO/ ARO/AIO-04 randomised Phase 3 trial
-
German Rectal Cancer Study Group
-
Rödel C, Liersch T, Becker H et al.; German Rectal Cancer Study Group. Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ ARO/AIO-04 randomised Phase 3 trial. Lancet Oncol. 13(7), 679-687 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, Issue.7
, pp. 679-687
-
-
Rödel, C.1
Liersch, T.2
Becker, H.3
-
21
-
-
84871725058
-
Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer
-
Gérard JP, Azria D, Gourgou-Bourgade S et al. Clinical outcome of the ACCORD 12/0405 PRODIGE 2 randomized trial in rectal cancer. J. Clin. Oncol. 30(36), 4558-4565 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.36
, pp. 4558-4565
-
-
Gérard, J.P.1
Azria, D.2
Gourgou-Bourgade, S.3
-
22
-
-
84864472128
-
A observational study of the efficacy and safety of capecitabine versus bolus infusional 5-fluorouracil in pre-operative chemoradiotherapy for locally advanced rectal cancer
-
Chen CF, Huang MY, Huang CJ et al. A observational study of the efficacy and safety of capecitabine versus bolus infusional 5-fluorouracil in pre-operative chemoradiotherapy for locally advanced rectal cancer. Int. J. Colorectal Dis. 27(6), 727-736 (2012).
-
(2012)
Int. J. Colorectal Dis.
, vol.27
, Issue.6
, pp. 727-736
-
-
Chen, C.F.1
Huang, M.Y.2
Huang, C.J.3
-
23
-
-
78049523725
-
Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: Final results of the VICTOR trial
-
Midgley RS, McConkey CC, Johnstone EC et al. Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial. J. Clin. Oncol. 28(30), 4575-4580 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.30
, pp. 4575-4580
-
-
Midgley, R.S.1
McConkey, C.C.2
Johnstone, E.C.3
-
24
-
-
42449147798
-
Aspirin helps prevent recurring colorectal adenomas -folic acid does not
-
Lundberg GD. Aspirin helps prevent recurring colorectal adenomas -folic acid does not. Medscape J. Med. 10(3), 69 (2008).
-
(2008)
Medscape J. Med.
, vol.10
, Issue.3
, pp. 69
-
-
Lundberg, G.D.1
-
25
-
-
83355163988
-
The utility of aspirin in Dukes C and high risk Dukes B colorectal cancer -the ASCOLT study: Study protocol for a randomized controlled trial
-
ASCOLT Trial Investigators.
-
Ali R, Toh HC, Chia WK; ASCOLT Trial Investigators. The utility of aspirin in Dukes C and high risk Dukes B colorectal cancer -the ASCOLT study: study protocol for a randomized controlled trial. Trials 12, 261 (2011).
-
(2011)
Trials
, vol.12
, pp. 261
-
-
Ali, R.1
Toh, H.C.2
Chia, W.K.3
-
26
-
-
84867817838
-
Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival
-
Liao X, Lochhead P, Nishihara R et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N. Engl. J. Med. 367(17), 1596-1606 (2012).
-
(2012)
N. Engl. J. Med.
, vol.367
, Issue.17
, pp. 1596-1606
-
-
Liao, X.1
Lochhead, P.2
Nishihara, R.3
-
27
-
-
84867047384
-
Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a Phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
-
Van Cutsem E, Tabernero J, Lakomy R et al. Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a Phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J. Clin. Oncol. 30(28), 3499-3506 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.28
, pp. 3499-3506
-
-
Van Cutsem, E.1
Tabernero, J.2
Lakomy, R.3
-
28
-
-
40749149728
-
Fédération Francophone de Cancérologie Digestive (FFCD) Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial
-
Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO); Australasian Gastro-Intestinal Trials Group (AGITG); EORTC Gastro-Intestinal Tract Cancer Group; Cancer Research UK
-
Nordlinger B, Sorbye H, Glimelius B et al.; EORTC Gastro-Intestinal Tract Cancer Group; Cancer Research UK; Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO); Australasian Gastro-Intestinal Trials Group (AGITG); Fédération Francophone de Cancérologie Digestive (FFCD). Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet 371(9617), 1007-1016 (2008).
-
(2008)
Lancet
, vol.371
, Issue.9617
, pp. 1007-1016
-
-
Nordlinger, B.1
Sorbye, H.2
Glimelius, B.3
-
29
-
-
68949217661
-
The role of preoperative chemotherapy in patients with resectable colorectal liver metastases
-
Benoist S, Nordlinger B. The role of preoperative chemotherapy in patients with resectable colorectal liver metastases. Ann. Surg. Oncol. 16(9), 2385-2390 (2009).
-
(2009)
Ann. Surg. Oncol.
, vol.16
, Issue.9
, pp. 2385-2390
-
-
Benoist, S.1
Nordlinger, B.2
-
30
-
-
4644320061
-
Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: A model to predict long-term survival
-
discussion 657
-
Adam R, Delvart V, Pascal G et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann. Surg. 240(4), 644-657; discussion 657 (2004).
-
(2004)
Ann. Surg.
, vol.240
, Issue.4
, pp. 644-657
-
-
Adam, R.1
Delvart, V.2
Pascal, G.3
-
31
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, André T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J. Clin. Oncol. 22(2), 229-237 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.2
, pp. 229-237
-
-
Tournigand, C.1
André, T.2
Achille, E.3
-
32
-
-
33846404530
-
The continuum of care: A paradigm for the management of metastatic colorectal cancer
-
Goldberg RM, Rothenberg ML, Van Cutsem E et al. The continuum of care: a paradigm for the management of metastatic colorectal cancer. Oncologist 12(1), 38-50 (2007).
-
(2007)
Oncologist
, vol.12
, Issue.1
, pp. 38-50
-
-
Goldberg, R.M.1
Rothenberg, M.L.2
Van Cutsem, E.3
-
33
-
-
34447255724
-
Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
-
FOCUS Trial Investigators; National Cancer. Research Institute Colorectal Clinical Studies Group
-
Seymour MT, Maughan TS, Ledermann JA et al.; FOCUS Trial Investigators; National Cancer Research Institute Colorectal Clinical Studies Group. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. Lancet 370(9582), 143-152 (2007).
-
(2007)
Lancet
, vol.370
, Issue.9582
, pp. 143-152
-
-
Seymour, M.T.1
Maughan, T.S.2
Ledermann, J.A.3
-
34
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Meridionale
-
Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G et al.; Gruppo Oncologico Dell'Italia Meridionale. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J. Clin. Oncol. 23(22), 4866-4875 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.22
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
-
35
-
-
84861198824
-
Biologic therapies in the metastatic colorectal cancer treatment continuum -applying current evidence to clinical practice
-
Peeters M, Price T. Biologic therapies in the metastatic colorectal cancer treatment continuum -applying current evidence to clinical practice. Cancer Treat. Rev. 38(5), 397-406 (2012).
-
(2012)
Cancer Treat. Rev.
, vol.38
, Issue.5
, pp. 397-406
-
-
Peeters, M.1
Price, T.2
-
36
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
-
Gruppo Oncologico Nord Ovest
-
Falcone A, Ricci S, Brunetti I et al.; Gruppo Oncologico Nord Ovest. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J. Clin. Oncol. 25(13), 1670-1676 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.13
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti, I.3
-
37
-
-
33645309877
-
FOLFOXIRI (folinic acid, 5-fluoro-uracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised Phase III trial from the Hellenic Oncology Research Group (HORG)
-
Souglakos J, Androulakis N, Syrigos K et al. FOLFOXIRI (folinic acid, 5-fluoro-uracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised Phase III trial from the Hellenic Oncology Research Group (HORG). Br. J. Cancer 94(6), 798-805 (2006).
-
(2006)
Br. J. Cancer
, vol.94
, Issue.6
, pp. 798-805
-
-
Souglakos, J.1
Androulakis, N.2
Syrigos, K.3
-
38
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized Phase III study
-
Saltz LB, Clarke S, Díaz-Rubio E et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized Phase III study. J. Clin. Oncol. 26(12), 2013-2019 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.12
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Díaz-Rubio, E.3
-
39
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350(23), 2335-2342 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
40
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
-
Eastern Cooperative Oncology Group Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ et al.; Eastern Cooperative Oncology Group Study E3200. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J. Clin. Oncol. 25(12), 1539-1544 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
41
-
-
77049088724
-
Targeted therapies in the management of colorectal carcinoma: Role of bevacizumab
-
Puthillath A, Patel A, Fakih MG. Targeted therapies in the management of colorectal carcinoma: role of bevacizumab. Onco. Targets. Ther. 2, 1-15 (2009).
-
(2009)
Onco. Targets. Ther.
, vol.2
, pp. 1-15
-
-
Puthillath, A.1
Patel, A.2
Fakih, M.G.3
-
42
-
-
84872600269
-
Overview of biomarkers in metastatic colorectal cancer: Tumour, blood and patient-related factors
-
Clarke SJ, Karapetis CS, Gibbs P et al. Overview of biomarkers in metastatic colorectal cancer: tumour, blood and patient-related factors. Crit. Rev. Oncol. Hematol. 85(2), 121-135 (2013).
-
(2013)
Crit. Rev. Oncol. Hematol.
, vol.85
, Issue.2
, pp. 121-135
-
-
Clarke, S.J.1
Karapetis, C.S.2
Gibbs, P.3
-
43
-
-
44249111440
-
EPIC: Phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
-
Sobrero AF, Maurel J, Fehrenbacher L et al. EPIC: Phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J. Clin. Oncol. 26(14), 2311-2319 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.14
, pp. 2311-2319
-
-
Sobrero, A.F.1
Maurel, J.2
Fehrenbacher, L.3
-
44
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N. Engl. J. Med. 360(14), 1408-1417 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.14
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
45
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J. Clin. Oncol. 26(10), 1626-1634 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.10
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
46
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J. Clin. Oncol. 27(5), 663-671 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.5
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
47
-
-
78149239651
-
Randomized Phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
-
Peeters M, Price TJ, Cervantes A et al. Randomized Phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J. Clin. Oncol. 28(31), 4706-4713 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.31
, pp. 4706-4713
-
-
Peeters, M.1
Price, T.J.2
Cervantes, A.3
-
48
-
-
78049341541
-
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
-
De Roock W, Jonker DJ, Di Nicolantonio F et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA 304(16), 1812-1820 (2010).
-
(2010)
JAMA
, vol.304
, Issue.16
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.J.2
Di Nicolantonio, F.3
-
49
-
-
84867117207
-
Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab
-
Tejpar S, Celik I, Schlichting M, Sartorius U, Bokemeyer C, Van Cutsem E. Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab. J. Clin. Oncol. 30(29), 3570-3577 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.29
, pp. 3570-3577
-
-
Tejpar, S.1
Celik, I.2
Schlichting, M.3
Sartorius, U.4
Bokemeyer, C.5
Van Cutsem, E.6
-
50
-
-
0034548712
-
K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon mutation or proto-oncogene overexpression
-
Guerrero S, Casanova I, Farré L, Mazo A, Capellà G, Mangues R. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon mutation or proto-oncogene overexpression. Cancer Res. 60(23), 6750-6756 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.23
, pp. 6750-6756
-
-
Guerrero, S.1
Casanova, I.2
Farré, L.3
Mazo, A.4
Capellà, G.5
Mangues, R.6
-
51
-
-
84887262713
-
KRAS mutations in colorectal trials using panitumumab
-
Peeters M. KRAS mutations in colorectal trials using panitumumab. Ann. Oncol. (2011).
-
(2011)
Ann. Oncol.
-
-
Peeters, M.1
-
52
-
-
79957523828
-
KRAS, BRAF, PIK3CA, and PTEN mutations: Implications for targeted therapies in metastatic colorectal cancer
-
De Roock W, De Vriendt V, Normanno N, Ciardiello F, Tejpar S. KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer. Lancet Oncol. 12(6), 594-603 (2011).
-
(2011)
Lancet Oncol.
, vol.12
, Issue.6
, pp. 594-603
-
-
De Roock, W.1
De Vriendt, V.2
Normanno, N.3
Ciardiello, F.4
-
53
-
-
79959337678
-
MRC COIN Trial Investigators. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised Phase 3 MRC COIN trial
-
Maughan TS, Adams RA, Smith CG et al.; MRC COIN Trial Investigators. Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised Phase 3 MRC COIN trial. Lancet 377(9783), 2103-2114 (2011).
-
(2011)
Lancet
, vol.377
, Issue.9783
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
-
54
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
Van Cutsem E, Köhne CH, Láng I et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J. Clin. Oncol. 29(15), 2011-2019 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.15
, pp. 2011-2019
-
-
Van Cutsem, E.1
Köhne, C.H.2
Láng, I.3
-
55
-
-
84861432557
-
Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDICVII study
-
Tveit KM, Guren T, Glimelius B et al. Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDICVII study. J. Clin. Oncol. 30(15), 1755-1762 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.15
, pp. 1755-1762
-
-
Tveit, K.M.1
Guren, T.2
Glimelius, B.3
-
56
-
-
78149250536
-
Randomized, Phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J et al. Randomized, Phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J. Clin. Oncol. 28(31), 4697-4705 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.31
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
57
-
-
80054738165
-
Addition of panitumumab to irinotecan: Results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC)
-
Seymour MT, Brown SR, Richman S et al. Addition of panitumumab to irinotecan: results of PICCOLO, a randomized controlled trial in advanced colorectal cancer (aCRC). J. Clin. Oncol. 29, Abstract 3523 (2011).
-
(2011)
J. Clin. Oncol. 29, Abstract
, vol.3523
-
-
Seymour, M.T.1
Brown, S.R.2
Richman, S.3
-
58
-
-
58749087713
-
Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience
-
Adams RA, Meade AM, Madi A et al. Toxicity associated with combination oxaliplatin plus fluoropyrimidine with or without cetuximab in the MRC COIN trial experience. Br. J. Cancer 100(2), 251-258 (2009).
-
(2009)
Br. J. Cancer
, vol.100
, Issue.2
, pp. 251-258
-
-
Adams, R.A.1
Meade, A.M.2
Madi, A.3
-
59
-
-
84863993927
-
Explaining the unexplainable: EGFR antibodies in colorectal cancer
-
Grothey A, Lenz HJ, Cats A et al. Explaining the unexplainable: EGFR antibodies in colorectal cancer. J. Clin. Oncol. 30(15), 1735-1737 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.15
, pp. 1735-1737
-
-
Grothey, A.1
Lenz, H.J.2
Cats, A.3
-
60
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
Tol J, Koopman M, Cats A et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N. Engl. J. Med. 360(6), 563-572 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.6
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
-
61
-
-
59949102930
-
A randomized Phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
Hecht JR, Mitchell E, Chidiac T et al. A randomized Phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J. Clin. Oncol. 27(5), 672-680 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.5
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
-
62
-
-
70350002279
-
Adverse effects of anticancer agents that target the VEGF pathway
-
Chen HX, Cleck JN. Adverse effects of anticancer agents that target the VEGF pathway. Nat. Rev. Clin. Oncol. 6(8), 465-477 (2009).
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, Issue.8
, pp. 465-477
-
-
Chen, H.X.1
Cleck, J.N.2
-
63
-
-
84989617477
-
Colorectal metastases to the liver: Present results and future strategies
-
Lise M, Da Pian PP, Nitti D, Pilati PL. Colorectal metastases to the liver: present results and future strategies. J. Surg. Oncol. Suppl. 2, 69-73 (1991).
-
(1991)
J. Surg. Oncol. Suppl.
, vol.2
, pp. 69-73
-
-
Lise, M.1
Da Pian, P.P.2
Nitti, D.3
Pilati, P.L.4
-
64
-
-
0029927548
-
Re-resection for colorectal liver metastasis
-
Bismuth H, Adam R, Navarro F, Castaing D, Engerran L, Abascal A. Re-resection for colorectal liver metastasis. Surg. Oncol. Clin. N. Am. 5(2), 353-364 (1996).
-
(1996)
Surg. Oncol. Clin. N. Am.
, vol.5
, Issue.2
, pp. 353-364
-
-
Bismuth, H.1
Adam, R.2
Navarro, F.3
Castaing, D.4
Engerran, L.5
Abascal, A.6
-
65
-
-
0035018397
-
Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal
-
Adam R, Avisar E, Ariche A et al. Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal. Ann. Surg. Oncol. 8(4), 347-353 (2001).
-
(2001)
Ann. Surg. Oncol.
, vol.8
, Issue.4
, pp. 347-353
-
-
Adam, R.1
Avisar, E.2
Ariche, A.3
-
66
-
-
23844448040
-
Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates
-
Folprecht G, Grothey A, Alberts S, Raab HR, Köhne CH. Neoadjuvant treatment of unresectable colorectal liver metastases: correlation between tumour response and resection rates. Ann. Oncol. 16(8), 1311-1319 (2005).
-
(2005)
Ann. Oncol.
, vol.16
, Issue.8
, pp. 1311-1319
-
-
Folprecht, G.1
Grothey, A.2
Alberts, S.3
Raab, H.R.4
Köhne, C.H.5
-
67
-
-
34347262406
-
The role of chemotherapy in the curative treatment of patients with liver metastases from colorectal cancer
-
viii
-
Leichman L. The role of chemotherapy in the curative treatment of patients with liver metastases from colorectal cancer. Surg. Oncol. Clin. N. Am. 16(3), 537-56, viii (2007).
-
(2007)
Surg. Oncol. Clin. N. Am.
, vol.16
, Issue.3
, pp. 537-556
-
-
Leichman, L.1
-
68
-
-
84863144441
-
Curative strategies for liver metastases from colorectal cancer: A review
-
Zdenkowski N, Chen S, van der Westhuizen A, Ackland S. Curative strategies for liver metastases from colorectal cancer: a review. Oncologist 17(2), 201-211 (2012).
-
(2012)
Oncologist
, vol.17
, Issue.2
, pp. 201-211
-
-
Zdenkowski, N.1
Chen, S.2
Van Der Westhuizen, A.3
Ackland, S.4
-
69
-
-
56749169353
-
Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: Results from a large observational cohort study (BRiTE)
-
Grothey A, Sugrue MM, Purdie DM et al. Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J. Clin. Oncol. 26(33), 5326-5334 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.33
, pp. 5326-5334
-
-
Grothey, A.1
Sugrue, M.M.2
Purdie, D.M.3
-
70
-
-
77951473745
-
The role of chemotherapy in managing patients with resectable liver metastases
-
Halfdanarson TR, Kendrick ML, Grothey A. The role of chemotherapy in managing patients with resectable liver metastases. Cancer J. 16(2), 125-131 (2010).
-
(2010)
Cancer J.
, vol.16
, Issue.2
, pp. 125-131
-
-
Halfdanarson, T.R.1
Kendrick, M.L.2
Grothey, A.3
-
71
-
-
84862026304
-
Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials
-
Bokemeyer C, Van Cutsem E, Rougier P et al. Addition of cetuximab to chemotherapy as first-line treatment for KRAS wild-type metastatic colorectal cancer: pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur. J. Cancer 48(10), 1466-1475 (2012).
-
(2012)
Eur. J. Cancer
, vol.48
, Issue.10
, pp. 1466-1475
-
-
Bokemeyer, C.1
Van Cutsem, E.2
Rougier, P.3
-
72
-
-
73249130298
-
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: The CELIM randomised Phase trial
-
Folprecht G, Gruenberger T, Bechstein WO et al. Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised Phase trial. Lancet Oncol. 11(1), 38-47 (2010).
-
(2010)
Lancet Oncol.
, vol.11
, Issue.1
, pp. 38-47
-
-
Folprecht, G.1
Gruenberger, T.2
Bechstein, W.O.3
-
73
-
-
34447277453
-
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A Phase III randomised controlled trial
-
Koopman M, Antonini NF, Douma J et al. Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a Phase III randomised controlled trial. Lancet 370(9582), 135-142 (2007).
-
(2007)
Lancet
, vol.370
, Issue.9582
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
-
74
-
-
80053384385
-
Fédération Francophone de Cancérologie Digestive (FFCD) 2000-05 Collaborative Group. Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, Phase 3 trial
-
Ducreux M, Malka D, Mendiboure J et al.; Fédération Francophone de Cancérologie Digestive (FFCD) 2000-05 Collaborative Group. Sequential versus combination chemotherapy for the treatment of advanced colorectal cancer (FFCD 2000-05): an open-label, randomised, Phase 3 trial. Lancet Oncol. 12(11), 1032-1044 (2011).
-
(2011)
Lancet Oncol.
, vol.12
, Issue.11
, pp. 1032-1044
-
-
Ducreux, M.1
Malka, D.2
Mendiboure, J.3
-
75
-
-
77955497309
-
Capecitabine, bevacizumab, and mitomycin in first-line treatment of metastatic colorectal cancer: Results of the Australasian Gastrointestinal Trials Group Randomized Phase III MAX Study
-
Tebbutt NC, Wilson K, Gebski VJ et al. Capecitabine, bevacizumab, and mitomycin in first-line treatment of metastatic colorectal cancer: results of the Australasian Gastrointestinal Trials Group Randomized Phase III MAX Study. J. Clin. Oncol. 28(19), 3191-3198 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.19
, pp. 3191-3198
-
-
Tebbutt, N.C.1
Wilson, K.2
Gebski, V.J.3
-
76
-
-
84861724011
-
Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: A subgroup analysis from the AGITG MAX trial: An international randomised controlled trial of Capecitabine, Bevacizumab and Mitomycin C
-
Price TJ, Zannino D, Wilson K et al. Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: a subgroup analysis from the AGITG MAX trial: an international randomised controlled trial of Capecitabine, Bevacizumab and Mitomycin C. Ann. Oncol. 23(6), 1531-1536 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, Issue.6
, pp. 1531-1536
-
-
Price, T.J.1
Zannino, D.2
Wilson, K.3
-
77
-
-
84857565176
-
'Watchful waiting' for metastatic colorectal cancer, antediluvian or an option to be considered again?
-
Price TJ, Townsend AR, Beeke C et al. 'Watchful waiting' for metastatic colorectal cancer, antediluvian or an option to be considered again? Asia. Pac. J. Clin. Oncol. 8(1), 10-13 (2012).
-
(2012)
Asia. Pac. J. Clin. Oncol.
, vol.8
, Issue.1
, pp. 10-13
-
-
Price, T.J.1
Townsend, A.R.2
Beeke, C.3
-
78
-
-
0141993765
-
Pharmacology of oxaliplatin in solid tumor patients with hepatic dysfunction: A preliminary report of the National Cancer Institute Organ Dysfunction Working Group
-
Doroshow JH, Synold TW, Gandara D et al. Pharmacology of oxaliplatin in solid tumor patients with hepatic dysfunction: a preliminary report of the National Cancer Institute Organ Dysfunction Working Group. Semin. Oncol. 30(4 Suppl. 15), 14-19 (2003).
-
(2003)
Semin. Oncol.
, vol.30
, Issue.4 SUPPL. 15
, pp. 14-19
-
-
Doroshow, J.H.1
Synold, T.W.2
Gandara, D.3
-
79
-
-
28444462862
-
Chemotherapy dosing in the setting of liver dysfunction
-
discussion 1063
-
Eklund JW, Trifilio S, Mulcahy MF. Chemotherapy dosing in the setting of liver dysfunction. Oncology (Williston Park, N.Y.) 19(8), 1057-1063; discussion 1063 (2005).
-
(2005)
Oncology (Williston Park, N.Y.)
, vol.19
, Issue.8
, pp. 1057-1063
-
-
Eklund, J.W.1
Trifilio, S.2
Mulcahy, M.F.3
-
80
-
-
0034886371
-
Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction
-
Ong SY, Clarke SJ, Bishop J, Dodds HM, Rivory LP. Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction. Anticancer. Drugs 12(7), 619-625 (2001).
-
(2001)
Anticancer. Drugs
, vol.12
, Issue.7
, pp. 619-625
-
-
Ong, S.Y.1
Clarke, S.J.2
Bishop, J.3
Dodds, H.M.4
Rivory, L.P.5
-
81
-
-
84872948810
-
Rechallenge with oxaliplatin and fluoropyrimidine for metastatic colorectal carcinoma after prior therapy
-
Townsend AR, Bishnoi S, Broadbridge V et al. Rechallenge with oxaliplatin and fluoropyrimidine for metastatic colorectal carcinoma after prior therapy. Am. J. Clin. Oncol. 36(1), 49-52 (2013).
-
(2013)
Am. J. Clin. Oncol.
, vol.36
, Issue.1
, pp. 49-52
-
-
Townsend, A.R.1
Bishnoi, S.2
Broadbridge, V.3
-
82
-
-
33644843853
-
OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer -a GERCOR study
-
Tournigand C, Cervantes A, Figer A et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer -a GERCOR study. J. Clin. Oncol. 24(3), 394-400 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.3
, pp. 394-400
-
-
Tournigand, C.1
Cervantes, A.2
Figer, A.3
-
83
-
-
73349089651
-
Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? the GERCOR OPTIMOX2 Study
-
Chibaudel B, Maindrault-Goebel F, Lledo G et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study. J. Clin. Oncol. 27(34), 5727-5733 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.34
, pp. 5727-5733
-
-
Chibaudel, B.1
Maindrault-Goebel, F.2
Lledo, G.3
-
84
-
-
79955506636
-
Intermittent versus continuous chemotherapy in advanced colorectal cancer: A randomised 'GISCAD' trial
-
Italian Group for the Study of Gastrointestinal Cancer-GISCAD
-
Labianca R, Sobrero A, Isa L et al.; Italian Group for the Study of Gastrointestinal Cancer-GISCAD. Intermittent versus continuous chemotherapy in advanced colorectal cancer: a randomised 'GISCAD' trial. Ann. Oncol. 22(5), 1236-1242 (2011).
-
(2011)
Ann. Oncol.
, vol.22
, Issue.5
, pp. 1236-1242
-
-
Labianca, R.1
Sobrero, A.2
Isa, L.3
-
85
-
-
79955153377
-
South Australian clinical registry for metastatic colorectal cancer
-
Neo EL, Beeke C, Price T et al. South Australian clinical registry for metastatic colorectal cancer. ANZ J. Surg. 81(5), 352-357 (2011).
-
(2011)
ANZ J. Surg.
, vol.81
, Issue.5
, pp. 352-357
-
-
Neo, E.L.1
Beeke, C.2
Price, T.3
-
86
-
-
84871720057
-
Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): A randomised Phase 3 trial
-
ML18147 Study Investigators
-
Bennouna J, Sastre J, Arnold D et al.; ML18147 Study Investigators. Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised Phase 3 trial. Lancet Oncol. 14(1), 29-37 (2013).
-
(2013)
Lancet Oncol.
, vol.14
, Issue.1
, pp. 29-37
-
-
Bennouna, J.1
Sastre, J.2
Arnold, D.3
-
87
-
-
84879793359
-
Results of a Phase III randomized, double-blind, placebo-controlled, multicenter trial (CORRECT) of regorafenib plus best supportive care (BSC) versus placebo plus BSC in patients (pts) with metastatic colorectal cancer (mCRC) who have progressed after standard therapies
-
San Francisco, CA, USA 19-21 January 2012 (Abstract LBA385)
-
Grothey A, Sobrero AF, Siena S et al. Results of a Phase III randomized, double-blind, placebo-controlled, multicenter trial (CORRECT) of regorafenib plus best supportive care (BSC) versus placebo plus BSC in patients (pts) with metastatic colorectal cancer (mCRC) who have progressed after standard therapies. Presented at: 2012 Gastrointestinal Cancers Symposium. San Francisco, CA, USA, 19-21 January 2012 (Abstract LBA385).
-
2012 Gastrointestinal Cancers Symposium
-
-
Grothey, A.1
Sobrero, A.F.2
Siena, S.3
-
88
-
-
84866925889
-
TAS-102 monotherapy for pretreated metastatic colorectal cancer: A doubleblind, randomised, placebo-controlled Phase 2 trial
-
Yoshino T, Mizunuma N, Yamazaki K et al. TAS-102 monotherapy for pretreated metastatic colorectal cancer: a doubleblind, randomised, placebo-controlled Phase 2 trial. Lancet Oncol. 13(10), 993-1001 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, Issue.10
, pp. 993-1001
-
-
Yoshino, T.1
Mizunuma, N.2
Yamazaki, K.3
-
89
-
-
84866143308
-
Phase III randomized trial of cetuximab (CET) plus either brivanib alaninate (BRIV) or placebo in patients (pts) with metastatic (MET) chemotherapy refractory K-RAS wild-type (WT) colorectal carcinoma (CRC): The NCIC Clinical Trials Group and AGITG CO.20 trial
-
Siu LL, Shapiro JD, Jonker DsJ et al. Phase III randomized trial of cetuximab (CET) plus either brivanib alaninate (BRIV) or placebo in patients (pts) with metastatic (MET) chemotherapy refractory K-RAS wild-type (WT) colorectal carcinoma (CRC): The NCIC Clinical Trials Group and AGITG CO.20 trial. J. Clin. Oncol. 30(Suppl. 4), Abstract 386 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.SUPPL. 4
, pp. 386
-
-
Siu, L.L.1
Shapiro, J.D.2
Jonker, D.S.J.3
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