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Volumn , Issue , 2005, Pages 135-154

Pharmacokinetics of gene delivery in cells

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EID: 84876848321     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/4-431-27879-6_11     Document Type: Chapter
Times cited : (2)

References (81)
  • 1
    • 1642443376 scopus 로고    scopus 로고
    • Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy
    • Akita H, Ito R, Khalil IA, Futaki S, Harashima H (2004) Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy. Mol Ther 9:443-451
    • (2004) Mol Ther , vol.9 , pp. 443-451
    • Akita, H.1    Ito, R.2    Khalil, I.A.3    Futaki, S.4    Harashima, H.5
  • 2
    • 0141851072 scopus 로고    scopus 로고
    • A model for the analysis of nonviral gene therapy
    • Banks GA, Roselli RJ, Chen R, Giorgio TD (2003) A model for the analysis of nonviral gene therapy. Gene Ther 10:1766-1775
    • (2003) Gene Ther , vol.10 , pp. 1766-1775
    • Banks, G.A.1    Roselli, R.J.2    Chen, R.3    Giorgio, T.D.4
  • 3
    • 0032539538 scopus 로고    scopus 로고
    • Monomolecular collapse of plasmid DNA into stable virus-like particles
    • Blessing T, Remy JS, Behr JP (1998) Monomolecular collapse of plasmid DNA into stable virus-like particles. Proc Natl Acad Sci USA 95:1427-1431
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1427-1431
    • Blessing, T.1    Remy, J.S.2    Behr, J.P.3
  • 5
    • 0032859928 scopus 로고    scopus 로고
    • A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA
    • Branden LJ, Mohamed AJ, Smith CI (1999) A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol 17:784-787
    • (1999) Nat Biotechnol , vol.17 , pp. 784-787
    • Branden, L.J.1    Mohamed, A.J.2    Smith, C.I.3
  • 6
  • 7
    • 0001362279 scopus 로고    scopus 로고
    • Enhancement of polylysine-mediated transferrinfection by nuclear localization sequences; polylysine does not function as a nuclear localization sequence
    • Chan CK, Jans DA (1999) Enhancement of polylysine-mediated transferrinfection by nuclear localization sequences; polylysine does not function as a nuclear localization sequence. Hum Gene Ther 10:1695-1702
    • (1999) Hum Gene Ther , vol.10 , pp. 1695-1702
    • Chan, C.K.1    Jans, D.A.2
  • 8
    • 0033764455 scopus 로고    scopus 로고
    • Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modified polylysine
    • Chan CK, Senden T, Jans DA (2000) Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modified polylysine. Gene Ther 7:1690-1697
    • (2000) Gene Ther , vol.7 , pp. 1690-1697
    • Chan, C.K.1    Senden, T.2    Jans, D.A.3
  • 9
    • 0242348399 scopus 로고    scopus 로고
    • Mechanisms and kinetics of liposome cell interaction
    • Duzgunes N, Nir S (1999) Mechanisms and kinetics of liposome cell interaction. Adv. Drug Delivery Rev. 40:3-18
    • (1999) Adv. Drug Delivery Rev , vol.40 , pp. 3-18
    • Duzgunes, N.1    Nir, S.2
  • 10
    • 0029979929 scopus 로고    scopus 로고
    • Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes
    • Erbacher P, Roche AC, Monsigny M, Midoux P (1996) Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes. Exp Cell Res 225:186-194
    • (1996) Exp Cell Res , vol.225 , pp. 186-194
    • Erbacher, P.1    Roche, A.C.2    Monsigny, M.3    Midoux, P.4
  • 11
    • 0029067792 scopus 로고
    • The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer
    • Farhood H, Serbina N, Huang L (1995) The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta 1235:289-295
    • (1995) Biochim Biophys Acta , vol.1235 , pp. 289-295
    • Farhood, H.1    Serbina, N.2    Huang, L.3
  • 14
    • 0042355293 scopus 로고    scopus 로고
    • Caveolaemediated internalization of extracellular HIV-1 Tat fusion proteins visualized in real time
    • Ferrari A, Pellegrini V, Arcangeli C, Fittipaldi A, Giacca M, Beltram F (2003) Caveolaemediated internalization of extracellular HIV-1 Tat fusion proteins visualized in real time. Mol. Ther. 8:284-294
    • (2003) Mol. Ther , vol.8 , pp. 284-294
    • Ferrari, A.1    Pellegrini, V.2    Arcangeli, C.3    Fittipaldi, A.4    Giacca, M.5    Beltram, F.6
  • 15
    • 0036804013 scopus 로고    scopus 로고
    • Arginine-rich peptides: Potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms
    • Futaki S (2002) Arginine-rich peptides: potential for intracellular delivery of macromolecules and the mystery of the translocation mechanisms. Int. J. Pharm. 245:1-7
    • (2002) Int. J. Pharm , vol.245 , pp. 1-7
    • Futaki, S.1
  • 16
    • 0035937124 scopus 로고    scopus 로고
    • Arginine-rich peptides: An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
    • Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y (2001a) Arginine-rich peptides: An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J. Biol. Chem. 276:5836-5840
    • (2001) J. Biol. Chem , vol.276 , pp. 5836-5840
    • Futaki, S.1    Suzuki, T.2    Ohashi, W.3    Yagami, T.4    Tanaka, S.5    Ueda, K.6    Sugiura, Y.7
  • 18
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of cationic liposome-mediated gene delivery by polycations
    • Gao X, Hunag L (1996) Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry 35:1027-1036
    • (1996) Biochemistry , vol.35 , pp. 1027-1036
    • Gao, X.1    Hunag, L.2
  • 21
    • 0035083066 scopus 로고    scopus 로고
    • Intracellular control of gene trafficking using liposomes as drug carriers
    • Harashima H, Shinohara Y, Kiwada H (2001) Intracellular control of gene trafficking using liposomes as drug carriers. Eur J Pharm Sci 13:85-89
    • (2001) Eur J Pharm Sci , vol.13 , pp. 85-89
    • Harashima, H.1    Shinohara, Y.2    Kiwada, H.3
  • 22
    • 0344707080 scopus 로고    scopus 로고
    • The role of helper lipids in cationic liposome-mediated gene transfer
    • Hui SW, Langner M, Zhao YL, Ross P, Hurley E, Chan K (1996) The role of helper lipids in cationic liposome-mediated gene transfer. Biophys J 71:590-599
    • (1996) Biophys J , vol.71 , pp. 590-599
    • Hui, S.W.1    Langner, M.2    Zhao, Y.L.3    Ross, P.4    Hurley, E.5    Chan, K.6
  • 24
    • 0035914989 scopus 로고    scopus 로고
    • Intracellular trafficking and transgene expression of viral and non-viral gene vectors
    • Kamiya H, Tsuchiya H, Yamazaki J, Harashima H (2001) Intracellular trafficking and transgene expression of viral and non-viral gene vectors. Adv. Drug Delivery Rev. 52:153-164
    • (2001) Adv. Drug Delivery Rev , vol.52 , pp. 153-164
    • Kamiya, H.1    Tsuchiya, H.2    Yamazaki, J.3    Harashima, H.4
  • 25
    • 0344120637 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic considerations in gene therapy
    • Kamiya H, Akita H, Harashima H (2003) Pharmacokinetic and pharmacodynamic considerations in gene therapy. Drug Discov Today 8:990-996
    • (2003) Drug Discov Today , vol.8 , pp. 990-996
    • Kamiya, H.1    Akita, H.2    Harashima, H.3
  • 26
    • 0021219156 scopus 로고
    • New procedure for DNA transfection with poly cation and dimethyl sulfoxide
    • Kawai S, Nishizawa M (1984) New procedure for DNA transfection with poly cation and dimethyl sulfoxide. Mol Cell Biol 4:1172-1174
    • (1984) Mol Cell Biol , vol.4 , pp. 1172-1174
    • Kawai, S.1    Nishizawa, M.2
  • 28
    • 1642578411 scopus 로고    scopus 로고
    • Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: Enhanced cellular association by hydrophobic core formation
    • Khalil IA, Futaki S, Niwa M, Baba Y, Kaji N, Kamiya H, Harashima H (2004) Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation. Gene Ther 11:636-644
    • (2004) Gene Ther , vol.11 , pp. 636-644
    • Khalil, I.A.1    Futaki, S.2    Niwa, M.3    Baba, Y.4    Kaji, N.5    Kamiya, H.6    Harashima, H.7
  • 29
    • 0035286969 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery: A mechanistic study
    • Kichler A, Leborgne C, Coeytaux E, Danos O (2001) Polyethylenimine-mediated gene delivery: a mechanistic study. J Gene Med 3:135-144
    • (2001) J Gene Med , vol.3 , pp. 135-144
    • Kichler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 30
    • 0035131596 scopus 로고    scopus 로고
    • Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
    • Kircheis R, Wightman L, Schreiber A, Robitza B, Rössler V, Kursa M, Wagner E (2001) Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 8:28-40
    • (2001) Gene Ther , vol.8 , pp. 28-40
    • Kircheis, R.1    Wightman, L.2    Schreiber, A.3    Robitza, B.4    Rössler, V.5    Kursa, M.6    Wagner, E.7
  • 31
    • 3242657221 scopus 로고    scopus 로고
    • Development of a nonviral multifunctional envelope-type nano device by a novel lipid film hydration method
    • Kogure K, Moriguchi R, Sasaki K, Ueno M, Futaki S, Harashima H (2004) Development of a nonviral multifunctional envelope-type nano device by a novel lipid film hydration method. J Cont Release 98:317-323
    • (2004) J Cont Release , vol.98 , pp. 317-323
    • Kogure, K.1    Moriguchi, R.2    Sasaki, K.3    Ueno, M.4    Futaki, S.5    Harashima, H.6
  • 32
    • 0028170358 scopus 로고
    • Multicompartment, numerical model of cellular events in the pharmacokinetics of gene therapies
    • Ledley TS, Ledley FD (1994) Multicompartment, numerical model of cellular events in the pharmacokinetics of gene therapies. Hum Gene Ther 5:679-691
    • (1994) Hum Gene Ther , vol.5 , pp. 679-691
    • Ledley, T.S.1    Ledley, F.D.2
  • 33
    • 0029932762 scopus 로고    scopus 로고
    • Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
    • Lee RJ, Huang L (1996) Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem 271:8481-8487
    • (1996) J Biol Chem , vol.271 , pp. 8481-8487
    • Lee, R.J.1    Huang, L.2
  • 34
    • 0032502017 scopus 로고    scopus 로고
    • Fluorescent virions: Dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells
    • Leopold PL, Ferris B, Grinberg I, Worgall S, Hackett NR, Crystal RG (1998) Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther 9:367-378
    • (1998) Hum Gene Ther , vol.9 , pp. 367-378
    • Leopold, P.L.1    Ferris, B.2    Grinberg, I.3    Worgall, S.4    Hackett, N.R.5    Crystal, R.G.6
  • 35
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipidprotamine-DNA (LPD) complexes
    • Li S, Huang L (1997) In vivo gene transfer via intravenous administration of cationic lipidprotamine-DNA (LPD) complexes. Gene Ther 4:891-900
    • (1997) Gene Ther , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 36
    • 0031851486 scopus 로고    scopus 로고
    • Characterization of cationic lipidprotamine-DNA (LPD) complexes for intravenous gene delivery
    • Li S, Rizzo MA, Bhattacharya S, Huang L (1998) Characterization of cationic lipidprotamine-DNA (LPD) complexes for intravenous gene delivery. Gene Ther 5:930-937
    • (1998) Gene Ther , vol.5 , pp. 930-937
    • Li, S.1    Rizzo, M.A.2    Bhattacharya, S.3    Huang, L.4
  • 37
    • 0032962978 scopus 로고    scopus 로고
    • Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: Implications for intravenous lipofection
    • Li S, Tseng WC, Stolz DB, Wu SP, Watkins SC, Huang L (1999) Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther 6:585-594
    • (1999) Gene Ther , vol.6 , pp. 585-594
    • Li, S.1    Tseng, W.C.2    Stolz, D.B.3    Wu, S.P.4    Watkins, S.C.5    Huang, L.6
  • 39
    • 0032805171 scopus 로고    scopus 로고
    • A nuclear localization signal can enhance both the nuclear transport and expression of 1kb DNA
    • Ludtke JJ, Zhang G, Sebestyen MG, Wolff JA (1999) A nuclear localization signal can enhance both the nuclear transport and expression of 1kb DNA. J Cell Sci 112(Pt 12):2033-2041
    • (1999) J Cell Sci , vol.112 , pp. 2033-2041
    • Ludtke, J.J.1    Zhang, G.2    Sebestyen, M.G.3    Wolff, J.A.4
  • 40
    • 0023772685 scopus 로고
    • Herpes simplex virus infection of the human sensory neuron. An electron microscopy study
    • Lycke E, Hamark B, Johansson M, Krotochwil A, Lycke J, Svennerholm B (1988) Herpes simplex virus infection of the human sensory neuron. An electron microscopy study. Arch Virol 101:87-104
    • (1988) Arch Virol , vol.101 , pp. 87-104
    • Lycke, E.1    Hamark, B.2    Johansson, M.3    Krotochwil, A.4    Lycke, J.5    Svennerholm, B.6
  • 44
    • 0037345795 scopus 로고    scopus 로고
    • Can nuclear localization signals enhance nuclear localization of plasmid DNA?
    • Nagasaki T, Myohoji T, Tachibana T, Futaki S, Tamagaki S (2003) Can nuclear localization signals enhance nuclear localization of plasmid DNA? Bioconjug Chem 14:282-286
    • (2003) Bioconjug Chem , vol.14 , pp. 282-286
    • Nagasaki, T.1    Myohoji, T.2    Tachibana, T.3    Futaki, S.4    Tamagaki, S.5
  • 45
    • 0034164025 scopus 로고    scopus 로고
    • Interactions of peptides with liposomes: Pore formation and fusion
    • Nir S, Nieva JL (2000) Interactions of peptides with liposomes: pore formation and fusion. Prog. Lipid Res. 39:181-206
    • (2000) Prog. Lipid Res , vol.39 , pp. 181-206
    • Nir, S.1    Nieva, J.L.2
  • 46
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood componets, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schüller S, Kircheis R, Wagner E (1999) PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood componets, extended circulation in blood and potential for systemic gene delivery. Gene Ther 6:595-605
    • (1999) Gene Ther , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schüller, S.3    Kircheis, R.4    Wagner, E.5
  • 47
    • 18744389736 scopus 로고    scopus 로고
    • Polyethylenimine-mediated cellular uptake, nucleus trafficking and expression of cytokine plasmid DNA
    • Oh YK, Suh D, Kim JM, Choi HG, Shin K, Ko JJ (2002) Polyethylenimine-mediated cellular uptake, nucleus trafficking and expression of cytokine plasmid DNA. Gene Ther 9:1627-1632
    • (2002) Gene Ther , vol.9 , pp. 1627-1632
    • Oh, Y.K.1    Suh, D.2    Kim, J.M.3    Choi, H.G.4    Shin, K.5    Ko, J.J.6
  • 48
    • 0343938838 scopus 로고    scopus 로고
    • DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
    • Oupicky D, Konak C, Ulbrich K, Wolfert MA, Seymour LW (2000) DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. J Control Release 65:149-171
    • (2000) J Control Release , vol.65 , pp. 149-171
    • Oupicky, D.1    Konak, C.2    Ulbrich, K.3    Wolfert, M.A.4    Seymour, L.W.5
  • 49
    • 0023883581 scopus 로고
    • PH-dependent fusion of phosphatidyl choline small vesicles
    • Parente RA, Nir S, Szoka FC (1988) pH-dependent fusion of phosphatidyl choline small vesicles. J. Biol. Chem. 263:4724-4730
    • (1988) J. Biol. Chem , vol.263 , pp. 4724-4730
    • Parente, R.A.1    Nir, S.2    Szoka, F.C.3
  • 50
    • 0024996257 scopus 로고
    • Association of a pH-sensitive peptide with membrane vesicles: Role of amino acid sequence
    • Parente RA, Nadasdi L, Subbarao NK, Szoka FC (1990) Association of a pH-sensitive peptide with membrane vesicles: role of amino acid sequence. Biochemistry 29:8713-8719
    • (1990) Biochemistry , vol.29 , pp. 8713-8719
    • Parente, R.A.1    Nadasdi, L.2    Subbarao, N.K.3    Szoka, F.C.4
  • 51
    • 0028199067 scopus 로고
    • The influence of endosomedisruptive peptides on gene transfer using synthetic virus-like gene transfer systems
    • Plank C, Oberhauser B, Mechtler K, Koch C, Wagner E (1994) The influence of endosomedisruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem 269:12918-12924
    • (1994) J Biol Chem , vol.269 , pp. 12918-12924
    • Plank, C.1    Oberhauser, B.2    Mechtler, K.3    Koch, C.4    Wagner, E.5
  • 52
    • 0032571392 scopus 로고    scopus 로고
    • Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard H, Remy JS, Loussouarn G, Demolombe S, Behr JP, Escande D (1998) Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 273:7507-7511
    • (1998) J Biol Chem , vol.273 , pp. 7507-7511
    • Pollard, H.1    Remy, J.S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.P.5    Escande, D.6
  • 53
    • 0033657521 scopus 로고    scopus 로고
    • Novel Tat-peptide chelates for direct transduction of Technetium-99 nm and Rhenium into human cells for imaging and radio therapy
    • Polyakov V, Sharma V, Dahlheimer JL, Pica CM, Luker GD, Piwnica-Worms D (2000) Novel Tat-peptide chelates for direct transduction of Technetium-99 nm and Rhenium into human cells for imaging and radio therapy. Bioconjugate Chem 11:762-771
    • (2000) Bioconjugate Chem , vol.11 , pp. 762-771
    • Polyakov, V.1    Sharma, V.2    Dahlheimer, J.L.3    Pica, C.M.4    Luker, G.D.5    Piwnica-Worms, D.6
  • 56
    • 0038176513 scopus 로고    scopus 로고
    • Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells
    • Rudolph C, Plank C, Lausier J, Schillinger U, Muller RH, Rosenecker J (2003) Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells. J Biol Chem 278:11411-11418
    • (2003) J Biol Chem , vol.278 , pp. 11411-11418
    • Rudolph, C.1    Plank, C.2    Lausier, J.3    Schillinger, U.4    Muller, R.H.5    Rosenecker, J.6
  • 57
    • 0034237577 scopus 로고    scopus 로고
    • Protein transduction: Unrestricted delivery into all cells?
    • Schwarze SR, Hruska KA, Dowdy SF (2000) Protein transduction: unrestricted delivery into all cells? Trends Cell Biol. 10, 290-295
    • (2000) Trends Cell Biol , vol.10 , pp. 290-295
    • Schwarze, S.R.1    Hruska, K.A.2    Dowdy, S.F.3
  • 59
    • 0030896925 scopus 로고    scopus 로고
    • Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus
    • Sodeik B, Ebersold MW, Helenius A (1997) Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J Cell Biol 136:1007-1021
    • (1997) J Cell Biol , vol.136 , pp. 1007-1021
    • Sodeik, B.1    Ebersold, M.W.2    Helenius, A.3
  • 60
    • 0030866647 scopus 로고    scopus 로고
    • Protamine sulfate enhances lipid-mediated gene transfer
    • Sorgi FL, Bhattacharya S, Huang L (1997) Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther 4:961-968
    • (1997) Gene Ther , vol.4 , pp. 961-968
    • Sorgi, F.L.1    Bhattacharya, S.2    Huang, L.3
  • 62
    • 0037169486 scopus 로고    scopus 로고
    • Possible existence of common internalisation mechanisms among arginine-rich peptides
    • Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y (2002) Possible existence of common internalisation mechanisms among arginine-rich peptides. J. Biol. Chem. 277:2437-2443
    • (2002) J. Biol. Chem , vol.277 , pp. 2437-2443
    • Suzuki, T.1    Futaki, S.2    Niwa, M.3    Tanaka, S.4    Ueda, K.5    Sugiura, Y.6
  • 64
    • 0036110686 scopus 로고    scopus 로고
    • Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes
    • Tachibana R, Harashima H, Ide N, Ukitsu S, Ohta Y, Suzuki N, Kikuchi H, Shinohara Y, Kiwada H (2002) Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes. Pharm Res 19:377-381
    • (2002) Pharm Res , vol.19 , pp. 377-381
    • Tachibana, R.1    Harashima, H.2    Ide, N.3    Ukitsu, S.4    Ohta, Y.5    Suzuki, N.6    Kikuchi, H.7    Shinohara, Y.8    Kiwada, H.9
  • 65
    • 0035915018 scopus 로고    scopus 로고
    • Quantitative studies on the nuclear transport of plasmid DNA and gene expression employing nonviral vectors
    • Tachibana R, Harashima H, Shinohara Y, Kiwada H (2001) Quantitative studies on the nuclear transport of plasmid DNA and gene expression employing nonviral vectors. Adv Drug Deliv Rev 52:219-226
    • (2001) Adv Drug Deliv Rev , vol.52 , pp. 219-226
    • Tachibana, R.1    Harashima, H.2    Shinohara, Y.3    Kiwada, H.4
  • 68
    • 0030775528 scopus 로고    scopus 로고
    • The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
    • Tang MX, Szoka FC (1997) The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther 4:823-832
    • (1997) Gene Ther , vol.4 , pp. 823-832
    • Tang, M.X.1    Szoka, F.C.2
  • 69
    • 0344494606 scopus 로고    scopus 로고
    • No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA
    • Tanimoto M, Kamiya H, Minakawa N, Matsuda A, Harashima H (2003) No enhancement of nuclear entry by direct conjugation of a nuclear localization signal peptide to linearized DNA. Bioconjug Chem 14:1197-1202
    • (2003) Bioconjug Chem , vol.14 , pp. 1197-1202
    • Tanimoto, M.1    Kamiya, H.2    Minakawa, N.3    Matsuda, A.4    Harashima, H.5
  • 70
    • 0345275894 scopus 로고    scopus 로고
    • Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential
    • Terrone D, Sang S L W, Roudaia L, Silvius JR (2003) Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential. Biochemistry 42:13787-13799
    • (2003) Biochemistry , vol.42 , pp. 13787-13799
    • Terrone, D.1    Sang, S.L.W.2    Roudaia, L.3    Silvius, J.R.4
  • 71
    • 0035902477 scopus 로고    scopus 로고
    • Tat peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in presence of metabolic inhibitors
    • Torchilin VP, Rammohan R, Weissig V, Levchenko TS (2001) Tat peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in presence of metabolic inhibitors. Proc. Natl. Acad. Sci. USA 98:8786-8791
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8786-8791
    • Torchilin, V.P.1    Rammohan, R.2    Weissig, V.3    Levchenko, T.S.4
  • 73
    • 0033553126 scopus 로고    scopus 로고
    • Mitosis enhances transgene expression of plasmid delivered by cationic liposomes
    • Tseng WC, Haselton FR, Giorgio TD (1999) Mitosis enhances transgene expression of plasmid delivered by cationic liposomes. Biochim Biophys Acta 1445:53-64
    • (1999) Biochim Biophys Acta , vol.1445 , pp. 53-64
    • Tseng, W.C.1    Haselton, F.R.2    Giorgio, T.D.3
  • 74
    • 0035189482 scopus 로고    scopus 로고
    • Quantitative analysis of synthetic gene delivery vector design properties
    • Varga CM, Hong K, Lauffenburger DA (2001) Quantitative analysis of synthetic gene delivery vector design properties. Mol Ther 4:438-446
    • (2001) Mol Ther , vol.4 , pp. 438-446
    • Varga, C.M.1    Hong, K.2    Lauffenburger, D.A.3
  • 75
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia JS, Stan RV, Dowdy SF (2004) Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat. Med. 10:310-315
    • (2004) Nat. Med , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 76
    • 0032580528 scopus 로고    scopus 로고
    • Effects of membrane-active agents in gene delivery
    • Wagner E (1998) Effects of membrane-active agents in gene delivery. J Control Release 53:155-158
    • (1998) J Control Release , vol.53 , pp. 155-158
    • Wagner, E.1
  • 77
    • 0026655684 scopus 로고
    • Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
    • Wagner E, Plank C, Zatloukal K, Cotten M, Birnstiel ML (1992) Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci U S A 89:7934-7938
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 7934-7938
    • Wagner, E.1    Plank, C.2    Zatloukal, K.3    Cotten, M.4    Birnstiel, M.L.5
  • 80
    • 0033618353 scopus 로고    scopus 로고
    • Nuclear import of plasmid DNA in digitoninpermeabilized cells requires both cytoplasmic factors and specific DNA sequences
    • Wilson GL, Dean BS, Wang G, Dean DA (1999) Nuclear import of plasmid DNA in digitoninpermeabilized cells requires both cytoplasmic factors and specific DNA sequences. J Biol Chem 274:22025-22032
    • (1999) J Biol Chem , vol.274 , pp. 22025-22032
    • Wilson, G.L.1    Dean, B.S.2    Wang, G.3    Dean, D.A.4
  • 81
    • 0033524453 scopus 로고    scopus 로고
    • Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus
    • Zanta MA, Belguise-Valladier P, Behr JP (1999) Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 96:91-96
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 91-96
    • Zanta, M.A.1    Belguise-Valladier, P.2    Behr, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.