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Volumn 5, Issue 5, 2013, Pages 423-427

Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DRUG DEVELOPMENT; MASS SPECTROMETRY; METHODOLOGY;

EID: 84876846773     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.1612     Document Type: Article
Times cited : (81)

References (29)
  • 1
    • 4944255180 scopus 로고    scopus 로고
    • Reaction discovery enabled by DNA-templated synthesis and in vitro selection
    • Kanan, M. W., Rozenman, M. M., Sakurai, K., Snyder, T. M. & Liu, D. R. Reaction discovery enabled by DNA-templated synthesis and in vitro selection. Nature 431, 545-549 (2004
    • (2004) Nature , vol.431 , pp. 545-549
    • Kanan, M.W.1    Rozenman, M.M.2    Sakurai, K.3    Snyder, T.M.4    Liu, D.R.5
  • 2
    • 33846783006 scopus 로고    scopus 로고
    • Discovery of chemical reactions through multidimensional screening
    • Beeler, A. B., Su, S., Singleton, C. A. & Porco, J. A. Jr. Discovery of chemical reactions through multidimensional screening. J. Am. Chem. Soc. 129, 1413-1419 (2007
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 1413-1419
    • Beeler, A.B.1    Su, S.2    Singleton, C.A.3    Porco Jr., J.A.4
  • 3
    • 36849070953 scopus 로고    scopus 로고
    • Development initial application of a hybridization-independent dna-encoded reaction discovery system compatible with organic solvents
    • Rozenman,M.M., Kanan,M.W. & Liu, D. R. Development and initial application of a hybridization-independent, DNA-encoded reaction discovery system compatible with organic solvents. J. Am. Chem. Soc. 129, 14933-14938 (2007
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 14933-14938
    • Rozenman, M.M.1    Kanan, M.W.2    Liu, D.R.3
  • 4
    • 70349110510 scopus 로고    scopus 로고
    • Development of an automated microfluidic reaction platform for multidimensional screening: Reaction discovery employing bicyclo[3.2.1]octanoid scaffolds
    • Goodell, J. R. et al. Development of an automated microfluidic reaction platform for multidimensional screening: Reaction discovery employing bicyclo[3.2.1]octanoid scaffolds. J. Org. Chem. 74, 6169-6180 (2009
    • (2009) J. Org. Chem , vol.74 , pp. 6169-6180
    • Goodell, J.R.1
  • 5
    • 62349121794 scopus 로고    scopus 로고
    • Mass spectrometric screening of chiral catalysts and catalyst mixtures
    • Mueller, C. A., Markert, C., Teichert, A. M. & Pfaltz, A. Mass spectrometric screening of chiral catalysts and catalyst mixtures. Chem. Commun. 13, 1607-1618 (2009
    • (2009) Chem. Commun , vol.13 , pp. 1607-1618
    • Mueller, C.A.1    Markert, C.2    Teichert, A.M.3    Pfaltz, A.4
  • 6
    • 77951671574 scopus 로고    scopus 로고
    • Catalyst selection based on intermediate stability measured by mass spectrometry
    • Wassenaar, J. et al. Catalyst selection based on intermediate stability measured by mass spectrometry. Nature Chem. 2, 417-420 (2010
    • (2010) Nature Chem , vol.2 , pp. 417-420
    • Wassenaar, J.1
  • 7
    • 79953856934 scopus 로고    scopus 로고
    • Determining the enantioselectivity of chiral catalysts by mass spectrometric screening of their racemic forms
    • Ebner, C., Muller, C. A., Markert, C. & Pfaltz, A. Determining the enantioselectivity of chiral catalysts by mass spectrometric screening of their racemic forms. J. Am. Chem. Soc. 133, 4710-4713 (2011
    • (2011) J. Am. Chem. Soc , vol.133 , pp. 4710-4713
    • Ebner, C.1    Muller, C.A.2    Markert, C.3    Pfaltz, A.4
  • 8
    • 79251640637 scopus 로고    scopus 로고
    • A biomolecule-compatible visible-light-induced azide reduction from a DNA-encoded reaction-discovery system
    • Chen, Y., Kamlet, A. S., Steinman, J. B. & Liu, D. R. A biomolecule-compatible visible-light-induced azide reduction from a DNA-encoded reaction-discovery system. Nature Chem. 3, 146-153 (2011
    • (2011) Nature Chem , vol.3 , pp. 146-153
    • Chen, Y.1    Kamlet, A.S.2    Steinman, J.B.3    Liu, D.R.4
  • 9
    • 80052629313 scopus 로고    scopus 로고
    • A simple, multidimensional approach to highthroughput discovery of catalytic reactions
    • Robbins, D. W. & Hartwig, J. F. A simple, multidimensional approach to highthroughput discovery of catalytic reactions. Science 333, 1423-1427 (2011
    • (2011) Science , vol.333 , pp. 1423-1427
    • Robbins, D.W.1    Hartwig, J.F.2
  • 10
    • 82255173962 scopus 로고    scopus 로고
    • Discovery of an a-amino C-H arylation reaction using the strategy of accelerated serendipity
    • McNally, A., Prier, C. K. & MacMillan, D. W. C. Discovery of an a-amino C-H arylation reaction using the strategy of accelerated serendipity. Science 334, 1114-1117 (2011
    • (2011) Science , vol.334 , pp. 1114-1117
    • McNally, A.1    Prier, C.K.2    MacMillan, D.W.C.3
  • 11
    • 80052599036 scopus 로고    scopus 로고
    • Combinatorial catalysis employing a visible enzymatic reacon in real time: Synthetically versatile (pseudo)halometalation/carbocyclizations
    • Friest, J. A., Broussy, S., Chung,W. J. & Berkowitz, D. B. Combinatorial catalysis employing a visible enzymatic reacon in real time: Synthetically versatile (pseudo)halometalation/carbocyclizations. Angew. Chem. Int. Ed. 50, 8895-8899 (2011
    • (2011) Angew. Chem. Int. Ed. , vol.50 , pp. 8895-8899
    • Friest, J.A.1    Broussy, S.2    Chung, W.J.3    Berkowitz, D.B.4
  • 12
    • 83655197599 scopus 로고    scopus 로고
    • Threecomponent reaction discovery enabled by mass spectrometry of self-assembled monolayers
    • Montavon, T. J., Li, J., Cabrera-Pardo, J. R., Mrksich, M. & Kozmin, S. A. Threecomponent reaction discovery enabled by mass spectrometry of self-assembled monolayers. Nature Chem. 4, 45-51 (2012
    • (2012) Nature Chem , vol.4 , pp. 45-51
    • Montavon, T.J.1    Li, J.2    Cabrera-Pardo, J.R.3    Mrksich, M.4    Kozmin, S.A.5
  • 13
    • 0032560748 scopus 로고    scopus 로고
    • High-throughput screening of solid-state catalyst libraries
    • Senkan, S. M. High-throughput screening of solid-state catalyst libraries. Nature 394, 350-353 (1998
    • (1998) Nature , vol.394 , pp. 350-353
    • Senkan, S.M.1
  • 14
    • 0029401607 scopus 로고
    • Use of the derivatizing agent, 4-aminobenzoic acid 2-(diethylamino)ethyl ester, for high-sensitivity detection of oligosaccharides by electrospray ionization mass spectrometry
    • Yoshino, K., Takao, T., Murata, H. & Shimonishi, Y. Use of the derivatizing agent, 4-aminobenzoic acid 2-(diethylamino)ethyl ester, for high-sensitivity detection of oligosaccharides by electrospray ionization mass spectrometry. Anal. Chem. 67, 4028-4031 (1995
    • (1995) Anal. Chem , vol.67 , pp. 4028-4031
    • Yoshino, K.1    Takao, T.2    Murata, H.3    Shimonishi, Y.4
  • 15
    • 0032435872 scopus 로고    scopus 로고
    • Malononitrile as a new derivatizing reagent for high-sensitivity analysis of oligosaccharides by electrospray ionization mass spectrometry
    • Ahn, Y. H. & Yoo, J. S. Malononitrile as a new derivatizing reagent for high-sensitivity analysis of oligosaccharides by electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 12, 2011-2015 (1998
    • (1998) Rapid Commun. Mass Spectrom , vol.12 , pp. 2011-2015
    • Ahn, Y.H.1    Yoo, J.S.2
  • 16
    • 0035825161 scopus 로고    scopus 로고
    • A mass spectrometric labeling strategy for high-throughput reaction evaluation and optimization: ExploringC-HActivation.Angew
    • Szewczyk, J.W., Zuckerman, R. L., Bergman, R. G. & Ellman, J. A. A mass spectrometric labeling strategy for high-throughput reaction evaluation and optimization: ExploringC-HActivation.Angew. Chem. Int. Ed. 40, 216-219 (2001
    • (2001) Chem. Int. Ed. , vol.40 , pp. 216-219
    • Szewczyk, J.W.1    Zuckerman, R.L.2    Bergman, R.G.3    Ellman, J.A.4
  • 18
    • 84055184868 scopus 로고    scopus 로고
    • Trimethoxyarene as highly ionizable tag for reaction analysis by atmospheric pressure photoionization mass spectrometry (APPI/MS): Exploration of heterocylic synthesis
    • Thuong, M. B. T. et al. Trimethoxyarene as highly ionizable tag for reaction analysis by atmospheric pressure photoionization mass spectrometry (APPI/MS): Exploration of heterocylic synthesis. Eur. J. Org. Chem. 2012, 85-92.
    • (2012) Eur. J. Org. Chem , pp. 85-92
    • Thuong, M.B.T.1
  • 19
    • 0032184398 scopus 로고    scopus 로고
    • Electron-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry
    • McCarley, T. D., McCarley, R. L. & Limbach, P. A. Electron-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chem. 70, 4376-4379 (1998
    • (1998) Anal. Chem , vol.70 , pp. 4376-4379
    • McCarley, T.D.1    McCarley, R.L.2    Limbach, P.A.3
  • 20
    • 0032875257 scopus 로고    scopus 로고
    • Influence of ionization energy on charge-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry
    • Macha, S. F., McCarley, T. D. & Limbach, P. A. Influence of ionization energy on charge-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chim. Acta 397, 235-245 (1999
    • (1999) Anal. Chim. Acta , vol.397 , pp. 235-245
    • Macha, S.F.1    McCarley, T.D.2    Limbach, P.A.3
  • 21
    • 4143058102 scopus 로고    scopus 로고
    • Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes
    • Zhang, L. & Kozmin, S. A. Brønsted acid-promoted cyclizations of siloxyalkynes with arenes and alkenes. J. Am. Chem. Soc. 126, 10204-10205 (2004
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 10204-10205
    • Zhang, L.1    Kozmin, S.A.2
  • 22
    • 4644331828 scopus 로고    scopus 로고
    • Gold-catalyzed cycloisomerizations of siloxy enynes to cyclohexadienes
    • Zhang, L. & Kozmin, S. A. Gold-catalyzed cycloisomerizations of siloxy enynes to cyclohexadienes. J. Am. Chem. Soc. 126, 11806-11807 (2004
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 11806-11807
    • Zhang, L.1    Kozmin, S.A.2
  • 23
    • 2942687050 scopus 로고    scopus 로고
    • Silver-catalyzed [2+2] cycloadditions of siloxyalkynes
    • Sweis, R., Schramm, M. P. & Kozmin, S. A. Silver-catalyzed [2+2] cycloadditions of siloxyalkynes. J. Am. Chem. Soc. 126, 7442-7443 (2004
    • (2004) J. Am. Chem. Soc , vol.126 , pp. 7442-7443
    • Sweis, R.1    Schramm, M.P.2    Kozmin, S.A.3
  • 24
    • 25844457731 scopus 로고    scopus 로고
    • Brønsted acid-promoted cyclizations of 1-siloxy- 1,5-diynes
    • Sun, J. & Kozmin, S. A. Brønsted acid-promoted cyclizations of 1-siloxy- 1,5-diynes. J. Am. Chem. Soc. 127, 13512-13513 (2005
    • (2005) J. Am. Chem. Soc , vol.127 , pp. 13512-13513
    • Sun, J.1    Kozmin, S.A.2
  • 25
    • 33746747614 scopus 로고    scopus 로고
    • Silver-catalyzed hydroamination of siloxy alkynes
    • Sun, J. & Kozmin, S. A. Silver-catalyzed hydroamination of siloxy alkynes. Angew. Chem. Int. Ed. 45, 4991-4993 (2006
    • (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 4991-4993
    • Sun, J.1    Kozmin, S.A.2
  • 26
    • 84861889756 scopus 로고    scopus 로고
    • Silver-catalyzed inverse electron-demand Diels-Alder reaction of 1,2-diazines with siloxy alkynes
    • Turkmen, Y., Montavon, T. J., Kozmin, S. A. & Rawal, V. H. Silver-catalyzed inverse electron-demand Diels-Alder reaction of 1,2-diazines with siloxy alkynes. J. Am. Chem. Soc. 134, 9062-9065 (2012
    • (2012) J. Am. Chem. Soc , vol.134 , pp. 9062-9065
    • Turkmen, Y.1    Montavon, T.J.2    Kozmin, S.A.3    Rawal, V.H.4
  • 28
    • 0001173186 scopus 로고
    • A regiocontrolled annulation approach to highly substituted aromatic compounds
    • Danheiser, R. L. & Gee, S. K. A regiocontrolled annulation approach to highly substituted aromatic compounds. J. Org. Chem. 49, 1672-1674 (1984
    • (1984) J. Org. Chem , vol.49 , pp. 1672-1674
    • Danheiser, R.L.1    Gee, S.K.2
  • 29
    • 0001182065 scopus 로고
    • Trialkylsilyloxyalkynes: Synthesis and aromatic annulation reactions
    • Danheiser, R. L., Nishida, A. N., Savariar, S. & Trova, M. P. Trialkylsilyloxyalkynes: Synthesis and aromatic annulation reactions. Tetrahedron Lett. 29, 4917-4920 (1988
    • (1988) Tetrahedron Lett , vol.29 , pp. 4917-4920
    • Danheiser, R.L.1    Nishida, A.N.2    Savariar, S.3    Trova, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.