Pharmacogenomics screening of HLA-B*1502 in epilepsy patients: How we do it in the UKM medical centre, Malaysia

Neurology Asia

Volumn 18, Issue SUPPL. 1, 2013, Pages 27-29

  Then, Sue Mian ^a   Rani, Zam Zureena Mohd ^a   Raymond, Azman Ali ^b   Jamal, Rahman ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b UNIVERSITI KEBANGSAAN MALAYSIA MEDICAL CENTER   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; HLA B ANTIGEN;

ANTICONVULSANT THERAPY; ARTICLE; CONTROLLED STUDY; COST CONTROL; COST EFFECTIVENESS ANALYSIS; DNA SEQUENCE; DRUG ERUPTION; DRUG SAFETY; EPILEPSY; GENETIC SCREENING; GENOTYPING TECHNIQUE; GOLD STANDARD; HEALTH CARE COST; HUMAN; MALAYSIA; MULTIPLEX POLYMERASE CHAIN REACTION; PHARMACOGENOMICS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 84876827993     PISSN: 18236138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Arif H, Buchsbaum R, Weintraub D, et al. Comparison and predictors of rash associated with 15 antiepileptic drugs. Neurology 2007; 68:1701-9.
2. Lim KS, Kwan P, Tan CT. Association of HLAB* 1502 allele and carbamazepine-induced severe adverse cutaneous drug reaction among Asians, a review. Neurol Asia 2008; 13:15-21.
3. Farkas R: Carbamazepine (marketed as CABATROL, EQUETRO, TEGRETOL and genericics): Stevens-Johnson syndrome, toxic epidermal necrolysis, and HLALA-B*1502. FDA Drug Safety Newsletter 2008; 1(3):35-7.
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9. Malaysian Society of Neurosciences. Consensus guidelines on the management of epilepsy 2010. In: Clinical Practice Guidelines [online]. Available at: http://www.neuro.org.my/pdf/ConsensusGuideline sontheManagementofEpilepsy2010.pdf
10. Then SM, Rani ZZM, Raymond AA, Ratnaningrum S, Jamal R. Frequency of the HLA-B*1502 allele contributing to carbamazepine-induced hypersensitivity reactions in a cohort of Malaysian epilepsy patients. Asian Pacific Journal of Allergy and Immunology 2011; 29(3):290-3.