Can mycobacterial katG genetic changes in isoniazid-resistant tuberculosis influence human disease features?

International Journal of Tuberculosis and Lung Disease

Volumn 17, Issue 5, 2013, Pages 644-651

  Escalante, Patricio ^a   McKean Cowdin, R ^b   Ramaswamy, S V ^c   Williams Bouyer, N ^d   Teeter, L D ^e   Jones, B E ^f   Graviss, E A ^e  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d University of Texas Medical Branch School of Medicine   (United States)

^e HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

KatG protein; Mycobacterium tuberculosis; Resistance; Virulence

Indexed keywords

ISONIAZID; TUBERCULOSTATIC AGENT;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; CASE CONTROL STUDY; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE ACTIVITY; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; KATG GENE; MALE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPUTUM CULTURE; TREATMENT DURATION; TUBERCULOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CATALASE; CHI-SQUARE DISTRIBUTION; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, BACTERIAL; FEMALE; GENOTYPE; HUMANS; ISONIAZID; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; ODDS RATIO; PHENOTYPE; RETROSPECTIVE STUDIES; SPUTUM; TIME FACTORS; TREATMENT OUTCOME; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY; VIRULENCE; YOUNG ADULT;

EID: 84876817976     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: 10.5588/ijtld.12.0380     Document Type: Article

References (35)

1. Aziz M A, Wright A, Laszlo A, et al. Epidemiology of anti-tuberculosis drug resistance (the Global Project on Anti-tuberculosis Drug Resistance Surveillance): an updated analysis. Lancet 2006; 368: 2142-2154. (Pubitemid 44914009)
2. Ramaswamy S V, Reich R, Dou S J, et al. Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2003; 47: 1241-1250. (Pubitemid 36372035)
3. Ramaswamy S, Musser J M. Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. Tubercle Lung Dis 1998; 79: 3-29. (Pubitemid 29050434)
4. Yu S, Girotto S, Lee C, Magliozzo R S. Reduced affinity for isoniazid in the S315T mutant of Mycobacterium tuberculosis katG is a key factor in antibiotic resistance. J Biol Chem 2003; 278: 14769-14775. (Pubitemid 36799801)
5. Wei C J, Lei B, Musser J M, Tu S C. Isoniazid activation defects in recombinant Mycobacterium tuberculosis catalase-peroxidase (katG) mutants evident in inhA inhibitor production. Antimicrob Agents Chemother 2003; 47: 670-675. (Pubitemid 36158099)
6. Rouse D A, DeVito J A, Li Z, Byer H, Morris S L. Site-directed mutagenesis of the katG gene of Mycobacterium tuberculosis: effects on catalase-peroxidase activities and isoniazid resistance. Mol Microbiol 1996; 22: 583-592. (Pubitemid 26373841)
7. Middlebrook G, Cohn M L. Some observations on the pathogenicity of isoniazid-resistant variants of tubercle bacilli. Science 1953; 118: 297-299.
8. Li Z, Kelley C, Collins F, Rouse D, Morris S. Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs. J Infect Dis 1998; 177: 1030-1035. (Pubitemid 28155158)
9. Bergval I L, Schuitema A R, Klatser P R, Anthony R M. Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance. J Antimicrob Chemother 2009; 64: 515-523.
10. Cattamanchi A, Dantes R B, Metcalfe J Z, et al. Clinical characteristics and treatment outcomes of patients with isoniazid-monoresistant tuberculosis. Clin Infect Dis 2009; 48: 179-185.
11. Hoopes A J, Kammerer J S, Harrington T A, Ijaz K, Armstrong L R. Isoniazid-monoresistant tuberculosis in the United States, 1993 to 2003. Arch Intern Med 2008; 168: 1984-1992.
12. Fox L, Kramer M R, Haim I, Priess R, Metvachuk A, Shitrit D. Comparison of isoniazid-monoresistant tuberculosis with drug-susceptible tuberculosis and multidrug-resistant tuberculosis. Eur J Clin Microbiol Infect Dis 2011; 30: 863-867.
13. Dantes R, Metcalfe J, Kim E, et al. Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid-monoresistant tuberculosis. PLoS ONE 2012; 7: e37956.
14. American Thoracic Society. Targeted tuberculin testing and treatment of latent tuberculosis infection. MMWR Recomm Rep 2000; 49: 1-51.
15. Lipsky B A, Gates J, Tenover F C, Plorde J J. Factors affecting the clinical value of microscopy for acid-fast bacilli. Rev Infect Dis 1984; 6: 214-222.
16. van Embden J D, Cave M D, Crawford J T, et al. Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol 1993; 31: 406-409. (Pubitemid 23028649)
17. Sreevatsan S, Pan X, Stockbauer K E, et al. Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sci USA 1997; 94: 9869-9874. (Pubitemid 27408157)
18. Kleinbaum D, Kupper L, Muller K, Nizam A. Applied regression analysis and other multivariable methods. 3rd ed. Boston, MA, USA: Duxbury Press, 1998.
19. Kremer K, Glynn J R, Lillebaek T, et al. Definition of the Beijing/W lineage of Mycobacterium tuberculosis on the basis of genetic markers. J Clin Microbiol 2004; 42: 4040-4049. (Pubitemid 39296121)
20. Rhee J T, Piatek A S, Small P M, et al. Molecular epidemiologic evaluation of transmissibility and virulence of Mycobacterium tuberculosis. J Clin Microbiol 1999; 37: 1764-1770. (Pubitemid 29235220)
21. Aaron L, Saadoun D, Calatroni I, et al. Tuberculosis in HIV-infected patients: a comprehensive review. Clin Microbiol Infect 2004; 10: 388-398. (Pubitemid 38714564)
22. Collins F M. Mycobacterial disease, immunosuppression and acquired immunodeficiency syndrome. Clin Microbiol Rev 1989; 2: 360-377. (Pubitemid 19249267)
23. Yang Z, Kong Y, Wilson F, et al. Identification of risk factors for extra-pulmonary tuberculosis. Clin Infect Dis 2004; 38: 199-205. (Pubitemid 38113027)
24. Hu Y, Ma X, Graviss E A, Wang W, Jiang W, Xu B. A major subgroup of Beijing family Mycobacterium tuberculosis is associated with multidrug resistance and increased transmissibility. Epidemiol Infect 2011; 139: 130-138.
25. Smith I. Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clin Microbiol Rev 2003; 16: 463-496. (Pubitemid 36871317)
26. Benator D, Bhattacharya M, Bozeman L, et al. Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial. Lancet 2002; 360: 528-534.
27. Kan B, Berggren I, Ghebremichael S, et al. Extensive transmission of an isoniazid-resistant strain of Mycobacterium tuberculosis in Sweden. Int J Tuberc Lung Dis 2008; 12: 199-204. (Pubitemid 351212413)
28. Maguire H, Brailsford S, Carless J, et al. Large outbreak of isoniazid-monoresistant tuberculosis in London, 1995 to 2006: case-control study and recommendations. Euro Surveill 2011; 16.
29. Gagneux S, Burgos M V, DeRiemer K, et al. Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis. PLoS Pathog 2006; 2: e61.
30. van Doorn H R, de Haas P E, Kremer K, Vandenbroucke-Grauls C M, Borgdorff M W, van Soolingen D. Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The Netherlands. Clin Microbiol Infect 2006; 12: 769-775. (Pubitemid 43983802)
31. Pym A S, Saint-Joanis B, Cole S T. Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans. Infect Immun 2002; 70: 4955-4960.
32. Ly L H, Russell M I, McMurray D N. Cytokine profiles in primary and secondary pulmonary granulomas of guinea pigs with tuberculosis. Am J Respir Cell Mol Biol 2008; 38: 455-462. (Pubitemid 351758692)
33. Yang Z, Yang D, Kong Y, et al. Clinical relevance of Mycobacterium tuberculosis plcD gene mutations. Am J Respir Crit Care Med 2005; 171: 1436-1442. (Pubitemid 40800518)
34. Kong Y, Cave M D, Zhang L, et al. Association between Mycobacterium tuberculosis Beijing/W lineage strain infection and extrathoracic tuberculosis: insights from epidemiologic and clinical characterization of the three principal genetic groups of M. tuberculosis clinical isolates. J Clin Microbiol 2007; 45: 409-414.
35. Fernando S L, Saunders B M, Sluyter R, et al. A polymorphism in the P2X7 gene increases susceptibility to extra-pulmonary tuberculosis. Am J Respir Crit Care Med 2007; 175: 360-366.