Targeting tumor microenvironment: The key role of immune system

BioImpacts

Volumn 2, Issue 1, 2012, Pages 1-3

  Barar, Jaleh ^a,b  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer detection; Cancer therapy; Macrophages immune system; Tumor microenvironment

Indexed keywords

CHEMOKINE;

ARTICLE; CANCER INVASION; CELLULAR IMMUNITY; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; LYMPHOCYTE HOMING; MOLECULAR DYNAMICS; PH MEASUREMENT; PROTEIN FUNCTION; TARGET CELL DESTRUCTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

EID: 84876816540     PISSN: 22285652     EISSN: 22285660     Source Type: Journal    
DOI: 10.5681/bi.2012.001     Document Type: Article

References (12)

1. Al-Sarireh B and Eremin O. 2000. Tumour-associated macrophages (TAMS): disordered function, immune suppression and progressive tumour growth. J R Coll Surg Edinb, 45(1), 1-16.
2. Ariztia EV, Lee CJ, Gogoi R and Fishman DA. 2006. The tumor microenvironment: key to early detection. Crit Rev Clin Lab Sci, 43(5-6), 393-425.
3. Augsten M, Hagglof C, Pena C and Ostman A. 2010. A digest on the role of the tumor microenvironment in gastrointestinal cancers. Cancer Microenviron, 3(1), 167-76.
4. Bingle L, Brown NJ and Lewis CE. 2002. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol, 196(3), 254-65.
5. Green CE, Liu T, Montel V, Hsiao G, Lester RD, Subramaniam S, et al. 2009. Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization. PLoS One, 4(8), e6713.
6. Heming TA, Dave SK, Tuazon DM, Chopra AK, Peterson JW and Bidani A. 2001. Effects of extracellular pH on tumour necrosis factor-alpha production by resident alveolar macrophages. Clinical science, 101(3), 267-74.
7. Lardner A. 2001. The effects of extracellular pH on immune function. Journal of leukocyte biology, 69(4), 522-30.
8. Lewis CE and Pollard JW. 2006. Distinct role of macrophages in different tumor microenvironments. Cancer research, 66(2), 605-12.
9. Liao D, Luo Y, Markowitz D, Xiang R and Reisfeld RA. 2009. Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model. PLoS One, 4(11), e7965.
10. Ma XJ, Dahiya S, Richardson E, Erlander M and Sgroi DC. 2009. Gene expression profiling of the tumor microenvironment during breast cancer progression. Breast Cancer Res, 11(1), R7.
11. Osinsky S, Bubnovskaya L, Ganusevich I, Kovelskaya A, Gumenyuk L, Olijnichenko G, et al. 2011. Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: interaction and impact on survival. Clin Transl Oncol, 13(2), 133-8.
12. Shih JU, Ang Y, Jeremy JWC and Pan-Chyr Y 2006. Tumor-Associated Macrophage: Its Role in Cancer Invasion and Metastasis. Journal of Cancer Molecules.