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Volumn 11, Issue 1, 2013, Pages

A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells

Author keywords

DC SIGN; Dendritic cells; Glomerulonephritis; Regulatory T cells

Indexed keywords

CD209 ANTIGEN; CREATININE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NITROGEN; P SELECTIN EPIDERMAL GROWTH FACTOR MONOCLONAL ANTIBODY; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UREA;

EID: 84876806139     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-103     Document Type: Article
Times cited : (11)

References (43)
  • 2
    • 33644638349 scopus 로고    scopus 로고
    • Renal fibrosis: new insights into the pathogenesis and therapeutics
    • 10.1038/sj.ki.5000054, 16408108
    • Liu Y. Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 2006, 69:213-217. 10.1038/sj.ki.5000054, 16408108.
    • (2006) Kidney Int , vol.69 , pp. 213-217
    • Liu, Y.1
  • 3
    • 0031058573 scopus 로고    scopus 로고
    • Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice
    • 10.1038/ki.1997.12, 8995722
    • Huang XR, Tipping PG, Shuo L, Holdsworth SR. Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice. Kidney Int 1997, 51:94-103. 10.1038/ki.1997.12, 8995722.
    • (1997) Kidney Int , vol.51 , pp. 94-103
    • Huang, X.R.1    Tipping, P.G.2    Shuo, L.3    Holdsworth, S.R.4
  • 4
    • 0032920361 scopus 로고    scopus 로고
    • Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis
    • 10.1046/j.1523-1755.1999.00369.x, 10200982
    • Holdsworth SR, Kitching AR, Tipping PG. Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. Kidney Int 1999, 55:1198-1216. 10.1046/j.1523-1755.1999.00369.x, 10200982.
    • (1999) Kidney Int , vol.55 , pp. 1198-1216
    • Holdsworth, S.R.1    Kitching, A.R.2    Tipping, P.G.3
  • 5
    • 0033940316 scopus 로고    scopus 로고
    • Crescentic glomerulonephritis-a manifestation of a nephritogenic Th1 response?
    • Kitching AR, Holdsworth SR, Tipping PG. Crescentic glomerulonephritis-a manifestation of a nephritogenic Th1 response?. Histol Histopathol 2000, 15:993-1003.
    • (2000) Histol Histopathol , vol.15 , pp. 993-1003
    • Kitching, A.R.1    Holdsworth, S.R.2    Tipping, P.G.3
  • 8
    • 66449114439 scopus 로고    scopus 로고
    • New roles revealed for T cells and DCs in glomerulonephritis
    • 10.1172/JCI39071, 2673880, 19422093
    • Kim AH, Markiewicz MA, Shaw AS. New roles revealed for T cells and DCs in glomerulonephritis. J Clin Invest 2009, 119:1074-1076. 10.1172/JCI39071, 2673880, 19422093.
    • (2009) J Clin Invest , vol.119 , pp. 1074-1076
    • Kim, A.H.1    Markiewicz, M.A.2    Shaw, A.S.3
  • 9
    • 75749089957 scopus 로고    scopus 로고
    • T cell cross-talk with kidney dendritic cells in glomerulonephritis
    • 10.1007/s00109-009-0541-5, 19798477
    • Panzer U, Kurts C. T cell cross-talk with kidney dendritic cells in glomerulonephritis. J Mol Med 2010, 88:19-26. 10.1007/s00109-009-0541-5, 19798477.
    • (2010) J Mol Med , vol.88 , pp. 19-26
    • Panzer, U.1    Kurts, C.2
  • 10
    • 7944236487 scopus 로고    scopus 로고
    • Dendritic cells and the immunity/tolerance decision
    • 10.1016/j.mehy.2004.02.061, 15533624
    • Usharauli D. Dendritic cells and the immunity/tolerance decision. Med Hypotheses 2005, 64:112-113. 10.1016/j.mehy.2004.02.061, 15533624.
    • (2005) Med Hypotheses , vol.64 , pp. 112-113
    • Usharauli, D.1
  • 11
    • 38649090061 scopus 로고    scopus 로고
    • Immunological decision-making: how does the immune system decide to mount a helper T-cell response?
    • 10.1111/j.1365-2567.2007.02719.x, 2433332, 17983439
    • Kaiko GE, Horvat JC, Beagley KW, Hansbro PM. Immunological decision-making: how does the immune system decide to mount a helper T-cell response?. Immunology 2008, 123:326-338. 10.1111/j.1365-2567.2007.02719.x, 2433332, 17983439.
    • (2008) Immunology , vol.123 , pp. 326-338
    • Kaiko, G.E.1    Horvat, J.C.2    Beagley, K.W.3    Hansbro, P.M.4
  • 12
    • 47749112843 scopus 로고    scopus 로고
    • Dendritic cell subsets: their roles in rheumatoid arthritis
    • Lebre MC, Tak PP. Dendritic cell subsets: their roles in rheumatoid arthritis. Acta Reumatol Port 2008, 33:35-45.
    • (2008) Acta Reumatol Port , vol.33 , pp. 35-45
    • Lebre, M.C.1    Tak, P.P.2
  • 13
    • 71649110874 scopus 로고    scopus 로고
    • Immunomodulation by semi-mature dendritic cells: a novel role of Toll-like receptors and interleukin-6
    • 10.1016/j.ijmm.2009.08.010, 19781988
    • Frick JS, Grunebach F, Autenrieth IB. Immunomodulation by semi-mature dendritic cells: a novel role of Toll-like receptors and interleukin-6. Int J Med Microbiol 2010, 300:19-24. 10.1016/j.ijmm.2009.08.010, 19781988.
    • (2010) Int J Med Microbiol , vol.300 , pp. 19-24
    • Frick, J.S.1    Grunebach, F.2    Autenrieth, I.B.3
  • 14
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg ML. Dendritic-cell control of pathogen-driven T-cell polarization. Nature reviews 2003, 93:984-993.
    • (2003) Nature reviews , vol.93 , pp. 984-993
    • Kapsenberg, M.L.1
  • 15
    • 0035955425 scopus 로고    scopus 로고
    • The plasticity of dendritic cell responses to pathogens and their components
    • 10.1126/science.294.5543.870, 11679675
    • Huang Q, Liu D, Majewski P, Schulte LC, Korn JM, Young RA, Lander ES, Hacohen N. The plasticity of dendritic cell responses to pathogens and their components. Science 2001, 294:870-875. 10.1126/science.294.5543.870, 11679675.
    • (2001) Science , vol.294 , pp. 870-875
    • Huang, Q.1    Liu, D.2    Majewski, P.3    Schulte, L.C.4    Korn, J.M.5    Young, R.A.6    Lander, E.S.7    Hacohen, N.8
  • 16
    • 59149106509 scopus 로고    scopus 로고
    • C-type lectins on dendritic cells: key modulators for the induction of immune responses
    • 10.1042/BST0361478, 19021579
    • van Kooyk Y. C-type lectins on dendritic cells: key modulators for the induction of immune responses. Biochem Soc Trans 2008, 36:1478-1481. 10.1042/BST0361478, 19021579.
    • (2008) Biochem Soc Trans , vol.36 , pp. 1478-1481
    • van Kooyk, Y.1
  • 17
    • 70349196800 scopus 로고    scopus 로고
    • Pathogen recognition by DC-SIGN shapes adaptive immunity
    • 10.2217/fmb.09.51, 19722841
    • Geijtenbeek TB, den Dunnen J, Gringhuis SI. Pathogen recognition by DC-SIGN shapes adaptive immunity. Future Microbiol 2009, 4:879-890. 10.2217/fmb.09.51, 19722841.
    • (2009) Future Microbiol , vol.4 , pp. 879-890
    • Geijtenbeek, T.B.1    den Dunnen, J.2    Gringhuis, S.I.3
  • 18
    • 2542474306 scopus 로고    scopus 로고
    • Self- and nonself-recognition by C-type lectins on dendritic cells
    • 10.1146/annurev.immunol.22.012703.104558, 15032573
    • Geijtenbeek TB, van Vliet SJ, Engering A, 't Hart BA, van Kooyk Y. Self- and nonself-recognition by C-type lectins on dendritic cells. Annu Rev Immunol 2004, 22:33-54. 10.1146/annurev.immunol.22.012703.104558, 15032573.
    • (2004) Annu Rev Immunol , vol.22 , pp. 33-54
    • Geijtenbeek, T.B.1    van Vliet, S.J.2    Engering, A.3    Thart, B.A.4    van Kooyk, Y.5
  • 19
    • 77349117251 scopus 로고    scopus 로고
    • Langerin-expressing dendritic cells in gut-associated lymphoid tissues
    • 10.1111/j.0105-2896.2009.00878.x, 20193022
    • Chang SY, Kweon MN. Langerin-expressing dendritic cells in gut-associated lymphoid tissues. Immunol Rev 2010, 234:233-246. 10.1111/j.0105-2896.2009.00878.x, 20193022.
    • (2010) Immunol Rev , vol.234 , pp. 233-246
    • Chang, S.Y.1    Kweon, M.N.2
  • 20
    • 77349120714 scopus 로고    scopus 로고
    • Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs
    • 10.1111/j.0105-2896.2009.00882.x, 20193029
    • Kerrigan AM, Brown GD. Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs. Immunol Rev 2010, 234:335-352. 10.1111/j.0105-2896.2009.00882.x, 20193029.
    • (2010) Immunol Rev , vol.234 , pp. 335-352
    • Kerrigan, A.M.1    Brown, G.D.2
  • 21
    • 77954534278 scopus 로고    scopus 로고
    • C-type lectin DC-SIGN: an adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity
    • 10.1016/j.cellsig.2010.03.018, 20363321
    • Svajger U, Anderluh M, Jeras M, Obermajer N. C-type lectin DC-SIGN: an adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity. Cell Signal 2010, 22:1397-1405. 10.1016/j.cellsig.2010.03.018, 20363321.
    • (2010) Cell Signal , vol.22 , pp. 1397-1405
    • Svajger, U.1    Anderluh, M.2    Jeras, M.3    Obermajer, N.4
  • 22
    • 79957869125 scopus 로고    scopus 로고
    • DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function
    • 10.1189/jlb.0810463, 21447648
    • Svajger U, Obermajer N, Anderluh M, Kos J, Jeras M. DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function. J Leukocyte Biol 2011, 89:893-905. 10.1189/jlb.0810463, 21447648.
    • (2011) J Leukocyte Biol , vol.89 , pp. 893-905
    • Svajger, U.1    Obermajer, N.2    Anderluh, M.3    Kos, J.4    Jeras, M.5
  • 24
    • 77950627537 scopus 로고    scopus 로고
    • Schistosoma mansoni worm glycolipids induce an inflammatory phenotype in human dendritic cells by cooperation of TLR4 and DC-SIGN
    • 10.1016/j.molimm.2010.01.014, 20170964
    • van Stijn CM, Meyer S, van den Broek M, Bruijns SC, van Kooyk Y, Geyer R, van Die I. Schistosoma mansoni worm glycolipids induce an inflammatory phenotype in human dendritic cells by cooperation of TLR4 and DC-SIGN. Mol Immunol 2010, 47:1544-1552. 10.1016/j.molimm.2010.01.014, 20170964.
    • (2010) Mol Immunol , vol.47 , pp. 1544-1552
    • van Stijn, C.M.1    Meyer, S.2    van den Broek, M.3    Bruijns, S.C.4    van Kooyk, Y.5    Geyer, R.6    van Die, I.7
  • 25
    • 20444503737 scopus 로고    scopus 로고
    • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin
    • 10.1016/j.jaci.2005.03.036, 15940144
    • Smits HH, Engering A, van der Kleij D, de Jong EC, Schipper K, van Capel TM, Zaat BA, Yazdanbakhsh M, Wierenga EA, van Kooyk Y, Kapsenberg ML. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immun 2005, 115:1260-1267. 10.1016/j.jaci.2005.03.036, 15940144.
    • (2005) J Allergy Clin Immun , vol.115 , pp. 1260-1267
    • Smits, H.H.1    Engering, A.2    van der Kleij, D.3    de Jong, E.C.4    Schipper, K.5    van Capel, T.M.6    Zaat, B.A.7    Yazdanbakhsh, M.8    Wierenga, E.A.9    van Kooyk, Y.10    Kapsenberg, M.L.11
  • 29
    • 10744220446 scopus 로고    scopus 로고
    • Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis
    • 10.1097/01.ASN.0000114553.36258.91, 14978163
    • Kruger T, Benke D, Eitner F, Lang A, Wirtz M, Hamilton-Williams EE, Engel D, Giese B, Müller-Newen G, Floege J, Kurts C. Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. J Am Soc Nephrol 2004, 15:613-621. 10.1097/01.ASN.0000114553.36258.91, 14978163.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 613-621
    • Kruger, T.1    Benke, D.2    Eitner, F.3    Lang, A.4    Wirtz, M.5    Hamilton-Williams, E.E.6    Engel, D.7    Giese, B.8    Müller-Newen, G.9    Floege, J.10    Kurts, C.11
  • 30
    • 79251567975 scopus 로고    scopus 로고
    • The vitamin D analog, TX527, promotes a human CD4 + CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation
    • 10.4049/jimmunol.1000695, 21131424
    • Baeke F, Korf H, Overbergh L, Verstuyf A, Thorrez L, Van Lommel L, Waer M, Schuit F, Gysemans C, Mathieu C. The vitamin D analog, TX527, promotes a human CD4 + CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation. J Immunol 2011, 186:132-142. 10.4049/jimmunol.1000695, 21131424.
    • (2011) J Immunol , vol.186 , pp. 132-142
    • Baeke, F.1    Korf, H.2    Overbergh, L.3    Verstuyf, A.4    Thorrez, L.5    Van Lommel, L.6    Waer, M.7    Schuit, F.8    Gysemans, C.9    Mathieu, C.10
  • 32
    • 3242677783 scopus 로고    scopus 로고
    • Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications
    • 10.1016/j.imlet.2004.04.015, 15234530
    • Rutella S, Lemoli RM. Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications. Immunol Lett 2004, 94:11-26. 10.1016/j.imlet.2004.04.015, 15234530.
    • (2004) Immunol Lett , vol.94 , pp. 11-26
    • Rutella, S.1    Lemoli, R.M.2
  • 33
    • 0028334128 scopus 로고
    • On the pathogenesis of chronic renal failure in primary glomerulopathies: a view from the interstitium
    • Bohle A, Strutz F, Muller GA. On the pathogenesis of chronic renal failure in primary glomerulopathies: a view from the interstitium. Exp Nephrol 1994, 2:205-210.
    • (1994) Exp Nephrol , vol.2 , pp. 205-210
    • Bohle, A.1    Strutz, F.2    Muller, G.A.3
  • 34
    • 23944511241 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells inhibit experimental anti-glomerular basement membrane glomerulonephritis in mice
    • 10.1681/ASN.2004100837, 15788479
    • Wolf D, Hochegger K, Wolf AM, Rumpold HF, Gastl G, Tilg H, Mayer G, Gunsilius E, Rosenkranz AR. CD4+CD25+ regulatory T cells inhibit experimental anti-glomerular basement membrane glomerulonephritis in mice. J Am Soc Nephrol 2005, 16:1360-1370. 10.1681/ASN.2004100837, 15788479.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1360-1370
    • Wolf, D.1    Hochegger, K.2    Wolf, A.M.3    Rumpold, H.F.4    Gastl, G.5    Tilg, H.6    Mayer, G.7    Gunsilius, E.8    Rosenkranz, A.R.9
  • 35
    • 35948929764 scopus 로고    scopus 로고
    • Role of T cells and dendritic cells in glomerular immunopathology
    • 10.1007/s00281-007-0096-x, 17955242
    • Kurts C, Heymann F, Lukacs-Kornek V, Boor P, Floege J. Role of T cells and dendritic cells in glomerular immunopathology. Semin Immunopathol 2007, 29:317-335. 10.1007/s00281-007-0096-x, 17955242.
    • (2007) Semin Immunopathol , vol.29 , pp. 317-335
    • Kurts, C.1    Heymann, F.2    Lukacs-Kornek, V.3    Boor, P.4    Floege, J.5
  • 36
    • 34547152610 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and the quest for transplant tolerance
    • 10.1038/nri2132, 17627284
    • Morelli AE, Thomson AW. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol 2007, 7:610-621. 10.1038/nri2132, 17627284.
    • (2007) Nat Rev Immunol , vol.7 , pp. 610-621
    • Morelli, A.E.1    Thomson, A.W.2
  • 37
    • 0034919344 scopus 로고    scopus 로고
    • Dendritic cells as a tool to induce anergic and regulatory T cells
    • 10.1016/S1471-4906(01)01952-4, 11429324
    • Jonuleit H, Schmitt E, Steinbrink K, Enk AH. Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol 2001, 22:394-400. 10.1016/S1471-4906(01)01952-4, 11429324.
    • (2001) Trends Immunol , vol.22 , pp. 394-400
    • Jonuleit, H.1    Schmitt, E.2    Steinbrink, K.3    Enk, A.H.4
  • 38
    • 0042971652 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells
    • 10.1146/annurev.immunol.21.120601.141040, 12615891
    • Steinman RM, Hawiger D, Nussenzweig MC. Tolerogenic dendritic cells. Annu Rev Immunol 2003, 21:685-711. 10.1146/annurev.immunol.21.120601.141040, 12615891.
    • (2003) Annu Rev Immunol , vol.21 , pp. 685-711
    • Steinman, R.M.1    Hawiger, D.2    Nussenzweig, M.C.3
  • 39
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?
    • Lutz MB, Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?. Trends Immunol 2003, 23:445-449.
    • (2003) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 40
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: the tolerogenic function of immature dendritic cells
    • 10.1046/j.1440-1711.2002.01115.x, 12225384
    • Mahnke K, Schmitt E, Bonifaz L, Enk AH, Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002, 80:477-483. 10.1046/j.1440-1711.2002.01115.x, 12225384.
    • (2002) Immunol Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 41
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance
    • 10.1073/pnas.231606698, 117564, 11773639
    • Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A 2002, 99:351-358. 10.1073/pnas.231606698, 117564, 11773639.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 42
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • 10.1084/jem.20011341, 2196016, 11781361
    • Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, Bogdan C, Erb K, Schuler G, Lutz MB. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med 2002, 195:15-21. 10.1084/jem.20011341, 2196016, 11781361.
    • (2002) J Exp Med , vol.195 , pp. 15-21
    • Menges, M.1    Rossner, S.2    Voigtlander, C.3    Schindler, H.4    Kukutsch, N.A.5    Bogdan, C.6    Erb, K.7    Schuler, G.8    Lutz, M.B.9
  • 43
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • 10.1038/39614, 9338786
    • Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, Roncarolo MG. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997, 389:737-742. 10.1038/39614, 9338786.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    de Vries, J.E.6    Roncarolo, M.G.7


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